List of works - Marc Mendillo

A conserved MutS homolog connector domain interface interacts with MutL homologs

scientific article

A genome-wide siRNA screen identifies proteasome addiction as a vulnerability of basal-like triple-negative breast cancer cells

scientific article published on August 2013

Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system.

scientific article

Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene

scientific article

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

scientific article

Coupling distant sites in DNA during DNA mismatch repair.

scholarly article

DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals.

scientific article published on 07 October 2013

Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway

scientific article (publication date: October 2013)

Escherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivo

scientific article

FIREWORKS: a bottom-up approach to integrative coessentiality network analysis

scientific article published on 16 December 2020

Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E).

scientific article

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

scientific article

HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state

scientific article published on 16 March 2022

High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

scientific article published on 31 October 2011

Inhibition of Msh6 ATPase activity by mispaired DNA induces a Msh2(ATP)-Msh6(ATP) state capable of hydrolysis-independent movement along DNA.

scientific article published in April 2006

Luminidependens (LD) is an Arabidopsis protein with prion behavior.

scientific article

Probing DNA- and ATP-mediated conformational changes in the MutS family of mispair recognition proteins using deuterium exchange mass spectrometry

scientific article

Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq

scientific article published on 12 November 2020

The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection

scientific article (publication date: February 2014)

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

scientific article

Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state

scientific article

List of works by Marc Mendillo

A conserved MutS homolog connector domain interface interacts with MutL homologs

A genome-wide siRNA screen identifies proteasome addiction as a vulnerability of basal-like triple-negative breast cancer cells

Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system.

Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome

Coupling distant sites in DNA during DNA mismatch repair.

DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals.

Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway

Escherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivo

FIREWORKS: a bottom-up approach to integrative coessentiality network analysis

Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E).

HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers

HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state

High levels of nuclear heat-shock factor 1 (HSF1) are associated with poor prognosis in breast cancer

Inhibition of Msh6 ATPase activity by mispaired DNA induces a Msh2(ATP)-Msh6(ATP) state capable of hydrolysis-independent movement along DNA.

Luminidependens (LD) is an Arabidopsis protein with prion behavior.

Probing DNA- and ATP-mediated conformational changes in the MutS family of mispair recognition proteins using deuterium exchange mass spectrometry

Quantitative and multiplexed chemical-genetic phenotyping in mammalian cells with QMAP-Seq

The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection

The reprogramming of tumor stroma by HSF1 is a potent enabler of malignancy

Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state