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List of works by Michel Simon

A 4.2 kb upstream region of the human corneodesmosin gene directs site-specific expression in hair follicles and hyperkeratotic epidermis of transgenic mice

scientific article

A new amyloidosis caused by fibrillar aggregates of mutated corneodesmosin.

scientific article published on 6 May 2010

Acefylline activates filaggrin deimination by peptidylarginine deiminases in the upper epidermis

scientific article published on 17 November 2015

Alterations in the desquamation-related proteolytic cleavage of corneodesmosin and other corneodesmosomal proteins in psoriatic lesional epidermis

scientific article published in July 2008

An intronic enhancer driven by NF-κB contributes to transcriptional regulation of peptidylarginine deiminase type I gene in human keratinocytes.

scientific article published on July 2010

Bleomycin hydrolase downregulation in lesional skin of adult atopic dermatitis patients is independent of FLG gene mutations.

scientific article

Corneodesmosomes and corneodesmosin: from the stratum corneum cohesion to the pathophysiology of genodermatoses.

scientific article published on May 2011

Corrigendum to: Defects of corneocyte structural proteins and epidermal barrier in atopic dermatitis.

scientific article published on 21 January 2016

Crucial roles of MZF1 and Sp1 in the transcriptional regulation of the peptidylarginine deiminase type I gene (PADI1) in human keratinocytes.

scientific article published on 13 September 2007

Defects of corneocyte structural proteins and epidermal barrier in atopic dermatitis

scientific article

Deimination and Peptidylarginine Deiminases in Skin Physiology and Diseases

scientific article published on 15 January 2020

Deimination and expression of peptidylarginine deiminases during cutaneous wound healing in mice

scientific article published on 01 May 2011

Deimination is regulated at multiple levels including auto-deimination of peptidylarginine deiminases.

scientific article published on 29 January 2010

Deimination of Human Hornerin Enhances its Processing by Calpain-1 and its Cross-Linking by Transglutaminases

scientific article published on 11 October 2016

Deimination of human filaggrin-2 promotes its proteolysis by calpain 1

scientific journal article

Deimination, Intermediate Filaments and Associated Proteins

scientific article published on 19 November 2020

Effects of environmental skin stressors on filaggrin degradation products: importance for eczema

scientific article published on 01 September 2018

Expression pattern of peptidylarginine deiminase in rat and human Schwann cells.

scientific article published in January 2008

Expression profile of cornified envelope structural proteins and keratinocyte differentiation-regulating proteins during skin barrier repair.

scientific article published in June 2012

Filaggrin Expression and Processing Deficiencies Impair Corneocyte Surface Texture and Stiffness in Mice

scientific article published on 31 August 2019

Filaggrin is expressed in the epithelial cells of the buccal mucosae

scientific article published on 24 September 2014

High TMEM45A expression is correlated to epidermal keratinization.

scientific article published in May 2014

Hornerin is a component of the epidermal cornified cell envelopes ⬇️

scientific article published on January 31, 2011

Hyaluronan Does Not Regulate Human Epidermal Keratinocyte Proliferation and Differentiation

scientific article published on December 2015

In a three-dimensional reconstructed human epidermis filaggrin-2 is essential for proper cornification

scientific article

In vivo quantification of epidermis pigmentation and dermis papilla density with reflectance confocal microscopy: variations with age and skin phototype ⬇️

scientific article published on April 1, 2012

Knockdown of filaggrin in a three-dimensional reconstructed human epidermis impairs keratinocyte differentiation

scientific article published on 13 June 2014

Lamellar bodies of human epidermis: proteomics characterization by high throughput mass spectrometry and possible involvement of CLIP-170 in their trafficking/secretion

scientific article published on 12 July 2008

Latent class analysis categorises chronic hand eczema patients according to skin barrier impairment

scientific article published on 17 November 2019

Long-range enhancer associated with chromatin looping allows AP-1 regulation of the peptidylarginine deiminase 3 gene in differentiated keratinocyte

scientific article

Long-range enhancer differentially regulated by c-Jun and JunD controls peptidylarginine deiminase-3 gene in keratinocytes.

scientific article published on 15 October 2008

Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome

scientific journal article

NF-Y and Sp1/Sp3 are involved in the transcriptional regulation of the peptidylarginine deiminase type III gene (PADI3) in human keratinocytes

scientific article

Nine procaspases are expressed in normal human epidermis, but only caspase-14 is fully processed

scientific article published on 01 March 2007

Peptidyl arginine deiminase type 2 (PAD-2) and PAD-4 but not PAD-1, PAD-3, and PAD-6 are expressed in rheumatoid arthritis synovium in close association with tissue inflammation

scientific article published in November 2007

Peptidylarginine Deiminase Inhibitor Cl-Amidine Attenuates Cornification and Interferes with the Regulation of Autophagy in Reconstructed Human Epidermis

scientific article published on 13 March 2019

Peptidylarginine deiminase isoforms 1-3 are expressed in the epidermis and involved in the deimination of K1 and filaggrin.

scientific article

Peptidylarginine deiminase isoforms are differentially expressed in the anagen hair follicles and other human skin appendages

scientific article published in July 2005

Peptidylarginine deiminases and deiminated proteins at the epidermal barrier

scientific article published on 29 June 2018

Peptidylarginine deiminases and deimination in biology and pathology: relevance to skin homeostasis.

scientific article

Positive change in hand care habits using therapeutic patient education in chronic hand eczema

scientific article published on 07 October 2019

Protease sensitivity of corneodesmosin variants encoded by the six more common CDSN haplotypes

scientific article published on 10 February 2011

Rab11a Is Essential for Lamellar Body Biogenesis in the Human Epidermis.

scientific article

Refined Immunochemical Characterization in Healthy Dog Skin of the Epidermal Cornification Proteins, Filaggrin, and Corneodesmosin

scientific article published on 10 September 2018

Regulation of the expression of peptidylarginine deiminase type II gene (PADI2) in human keratinocytes involves Sp1 and Sp3 transcription factors.

scientific article published in May 2005

Skin barrier in atopic dermatitis.

scientific article published on January 2014

Stabilization of microtubules restores barrier function after cytokine-induced defects in reconstructed human epidermis

scientific article published on 18 April 2018

Staphylococcus aureus density on lesional and nonlesional skin is strongly associated with disease severity in atopic dermatitis

scientific article published on 11 November 2015

The 3′-UTR AACCins5874 in the stratum corneum chymotryptic enzyme gene (SCCE/KLK7), associated with atopic dermatitis; causes an increased mRNA expression without altering its stability

scientific article published in February 2011

The Actin-Based Motor Myosin Vb Is Crucial to Maintain Epidermal Barrier Integrity

scientific article published on 17 January 2019

The Amino-Terminal Part of Human FLG2 Is a Component of Cornified Envelopes

scientific article published on 05 December 2018

The peptidylarginine deiminases expressed in human epidermis differ in their substrate specificities and subcellular locations.

scientific article

Topographical and nano-mechanical characterization of native corneocytes using atomic force microscopy

scientific article published on 28 April 2014

Update on peptidylarginine deiminases and deimination in skin physiology and severe human diseases.

scientific article published on June 2007

Update on the epidermal differentiation complex.

scientific article published on January 2012

Variant PADI3 in Central Centrifugal Cicatricial Alopecia

scientific article published on 13 February 2019

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