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List of works by Ross D. Hannan

A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells.

scientific article

A functional genetic screen defines the AKT-induced senescence signaling network

scientific article published on 08 July 2019

A functional siRNA screen identifies genes modulating angiotensin II-mediated EGFR transactivation.

scientific article published on 17 September 2013

A novel mouse model of atherosclerotic plaque instability for drug testing and mechanistic/therapeutic discoveries using gene and microRNA expression profiling

scientific article

A novel role for the Pol I transcription factor UBTF in maintaining genome stability through the regulation of highly transcribed Pol II genes

scientific article

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

scientific article published on 22 January 2019

A specific role for AKT3 in the genesis of ovarian cancer through modulation of G(2)-M phase transition

scientific article published in December 2006

AKT promotes rRNA synthesis and cooperates with c-MYC to stimulate ribosome biogenesis in cancer

scientific article

AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-Myc B-cell lymphoma in vivo

scientific article published on 13 February 2013

AKT-independent PI3-K signaling in cancer - emerging role for SGK3.

scientific article published on 26 August 2013

Adenovirus-mediated delivery of relaxin reverses cardiac fibrosis

scientific article published on 22 September 2007

Adrenergic agents, but not triiodo-L-thyronine induce c-fos and c-myc expression in the rat heart

scientific article published in March 1991

Amino acid-dependent signaling via S6K1 and MYC is essential for regulation of rDNA transcription

scientific article published on 30 June 2016

An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF

scientific article (publication date: November 2001)

Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis

scientific article

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

scientific article published on 26 May 2020

Cardiac hypertrophy in vivo is associated with increased expression of the ribosomal gene transcription factor UBF.

scientific article

Cardiac hypertrophy: a matter of translation.

scientific article

Cardiovascular role of urotensin II: effect of chronic infusion in the rat.

scientific article published in October 2004

Cellular regulation of ribosomal DNA transcription:both rat and Xenopus UBF1 stimulate rDNA transcription in 3T3 fibroblasts

scientific article

Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere

scientific article

Chromatin organization and expression

scientific article published on 14 April 2008

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

scientific article

Combined angiotensin and endothelin receptor blockade attenuates adverse cardiac remodeling post-myocardial infarction in the rat: possible role of transforming growth factor beta(1).

scientific article

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas

scientific article published on 12 February 2013

Conditional inactivation of Upstream Binding Factor reveals its epigenetic functions and the existence of a somatic nucleolar precursor body

scientific article

Cross talk between corticosteroids and alpha-adrenergic signalling augments cardiomyocyte hypertrophy: a possible role for SGK1.

scientific article

Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models

scientific article

Dysregulation of the basal RNA polymerase transcription apparatus in cancer

scientific article published on May 2013

Expression of c-fos and related genes in the rat heart in response to norepinephrine.

scientific article

Expression, regulation and putative nutrient-sensing function of taste GPCRs in the heart

scientific article

First-in-Human RNA Polymerase I Transcription Inhibitor CX-5461 in Patients with Advanced Hematologic Cancers: Results of a Phase I Dose-Escalation Study

scientific article published on 15 May 2019

Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

scientific article published on 25 August 2015

Hfp inhibits Drosophila myc transcription and cell growth in a TFIIH/Hay-dependent manner

scientific article

Hfp, the Drosophila homolog of the mammalian c-myc transcriptional-repressor and tumor suppressor FIR, inhibits dmyc transcription and cell growth.

scientific article published in April 2011

Hijacking epidermal growth factor receptors by angiotensin II: new possibilities for understanding and treating cardiac hypertrophy.

scientific article

Identification of a mammalian RNA polymerase I holoenzyme containing components of the DNA repair/replication system.

scientific article published on September 1999

Implications of epithelial-mesenchymal plasticity for heterogeneity in colorectal cancer.

scientific article

Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population

scientific article

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

scientific article

Inositol polyphosphate 1-phosphatase is a novel antihypertrophic factor

scientific article

Localization of c-myc protooncogene expression in the rat heart in vivo and in the isolated, perfused heart following treatment with norepinephrine

scientific article published on 01 April 1994

MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation

scientific article published on 29 July 2004

Migration of Small Ribosomal Subunits on the 5' Untranslated Regions of Capped Messenger RNA

scientific article published on 10 September 2019

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity

scientific article published on 01 March 2015

PR55α-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity.

scientific article published on 17 March 2014

Proliferation of neointimal smooth muscle cells after arterial injury. Dependence on interactions between fibroblast growth factor receptor-2 and fibroblast growth factor-9

scientific journal article

Regulation of rDNA transcription factors during cardiomyocyte hypertrophy induced by adrenergic agents

scientific article published on 01 April 1995

Regulation of rDNA transcription in response to growth factors, nutrients and energy

scientific article

Regulation of ribosomal DNA transcription during contraction-induced hypertrophy of neonatal cardiomyocytes.

scientific article

Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression

scientific article published on 10 July 2020

Synergistic inhibition of ovarian cancer cell growth by combining selective PI3K/mTOR and RAS/ERK pathway inhibitors

scientific article published on 3 September 2013

Targeting RNA polymerase I to treat MYC-driven cancer.

scientific article published on 10 March 2014

Targeting RNA polymerase I transcription and the nucleolus for cancer therapy

scientific article

Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth.

scientific article published on 15 December 2010

Targeting the nucleolus for cancer-specific activation of p53.

scientific article published on 28 August 2013

The 'Odd Pols' are even when it comes to controlling cell function. Conference on RNA Polymerases I and III.

scientific article published on 31 October 2008

The RNA polymerase I transcription inhibitor CX-5461 cooperates with topoisomerase 1 inhibition by enhancing the DNA damage response in homologous recombination-proficient high-grade serous ovarian cancer

scientific article published on 11 November 2020

The long noncoding RNA lncNB1 promotes tumorigenesis by interacting with ribosomal protein RPL35

scientific article published on 05 November 2019

The mTORC1 inhibitor everolimus prevents and treats Eμ-Myc lymphoma by restoring oncogene-induced senescence

scientific article published on 14 December 2012

The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy

scientific article

The renin-angiotensin system and cancer: old dog, new tricks.

scientific article published on 22 October 2010

Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation

scientific article published on 11 July 2008

Urotensin II promotes hypertrophy of cardiac myocytes via mitogen-activated protein kinases

scientific article

Urotensin II: the old kid in town.

scientific article published on May 2004

Widespread FRA1-dependent control of mesenchymal transdifferentiation programs in colorectal cancer cells

scientific article

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