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List of works by Leah C. Kottyan

17β-Estradiol protects the esophageal epithelium from IL-13-induced barrier dysfunction and remodeling

scientific article published on 20 December 2018

A Novel Pkhd1 Mutation Interacts with the Nonobese Diabetic Genetic Background To Cause Autoimmune Cholangitis

scientific article

A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus

scholarly article by Zubin Patel published in April 2018

Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations

scientific article published on 26 October 2013

Assessment of active play, inactivity and perceived barriers in an inner city neighborhood.

scientific article published on June 2014

Association of eosinophilic esophagitis and hypertrophic cardiomyopathy.

scientific article published on 02 October 2015

Association of systemic lupus erythematosus with uranium exposure in a community living near a uranium-processing plant: a nested case-control study

scientific article

Calpain-14 and its association with eosinophilic esophagitis.

scientific article published on 25 January 2017

Comprehensive Review of Steroid-Sensitive Nephrotic Syndrome Genetic Risk Loci and Transcriptional Regulation as a Possible Mechanistic Link to Disease Risk

scientific article published on 16 October 2020

DNA repair in lupus

scientific article published on 18 September 2014

Eosinophil viability is increased by acidic pH in a cAMP- and GPR65-dependent manner

scientific article published on 29 July 2009

Eosinophilic esophagitis (EoE) genetic susceptibility is mediated by synergistic interactions between EoE-specific and general atopic disease loci

scientific article published on 9 November 2017

Eosinophilic esophagitis-linked calpain 14 is an IL-13-induced protease that mediates esophageal epithelial barrier impairment.

scientific article published on April 2016

Erratum: Therapeutic Targeting of Follicular T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells

scientific article published on 25 August 2020

Genetic Associations with Gestational Duration and Spontaneous Preterm Birth

scientific article published on 6 September 2017

Genetic architecture distinguishes systemic juvenile idiopathic arthritis from other forms of juvenile idiopathic arthritis: clinical and therapeutic implications

article

Genetic influences on susceptibility to rheumatoid arthritis in African-Americans

scientific article published on 01 March 2019

Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.

scientific article published on 29 June 2012

Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitis

article

Genetic variants with gene regulatory effects are associated with diisocyanate-induced asthma

journal article published in 2018

Genetic, Inflammatory, and Epithelial Cell Differentiation Factors Control Expression of Human Calpain-14

scientific article published on 07 March 2019

Genetics of eosinophilic esophagitis

scientific article published on 22 February 2017

Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease

scientific article

Global discovery of lupus genetic risk variant allelic enhancer activity

scientific article published on 12 March 2021

HLA-DRB1*11 and variants of the MHC class II locus are strong risk factors for systemic juvenile idiopathic arthritis

scientific article

IL-33 promotes type 1 cytokine expression via p38 MAPK in human NK cells

scientific article published on 04 February 2020

IRF5 gene polymorphisms in melanoma

scientific article

Identification of novel coding mutation in C1qA gene in an African-American pedigree with lupus and C1q deficiency

scientific article

Immunology of the Ancestral Differences in Eosinophilic Esophagitis

scientific article published on 07 November 2018

Impact of Population Stratification on Family-Based Association in an Admixed Population

scientific article published on 4 May 2015

Imputation and quality control steps for combining multiple genome-wide datasets

scientific article

Increased susceptibility of 129SvEvBrd mice to IgE-Mast cell mediated anaphylaxis

scientific article

Inference of Causal Relationships Between Genetic Risk Factors for Cardiometabolic Phenotypes and Female‐Specific Health Conditions

scientific article published in 2023

Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression

scientific article

Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery

scientific article published on 06 April 2022

Lupus risk variants in the PXK locus alter B-cell receptor internalization

scientific article

Making it big in allergy

scientific article published in January 2015

Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus

scientific article published on 03 December 2020

Meta-analysis of differential gene co-expression: application to lupus

scientific article published on January 2015

Modeling of multivariate longitudinal phenotypes in family genetic studies with Bayesian multiplicity adjustment

scientific article published on 17 June 2014

Nanovesicle-targeted Kv1.3 knockdown in memory T cells suppresses CD40L expression and memory phenotype

scientific article published on 16 March 2016

New developments in patients with eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERS Symposium at the 2018 American Academy of Allergy, Asthma & Immunology Meeting

article published in 2018

Noncoding Variants as Genetic Contributors to Autoimmune Disease Pathogenesis

scientific article published on 01 February 2020

Novel variations in the adiponectin gene (ADIPOQ) may affect distribution of oligomeric complexes

scientific article published on 14 December 2012

On family-based genome-wide association studies with large pedigrees: observations and recommendations.

scientific article published on 17 June 2014

Phenome-wide association study (PheWAS) in EMR-linked pediatric cohorts, genetically links PLCL1 to speech language development and IL5-IL13 to Eosinophilic Esophagitis

scientific article

Runx1 shapes the chromatin landscape via a cascade of direct and indirect targets

scientific article published on 10 June 2021

SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression

scientific article published on 08 January 2021

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay (EMSA) and DNA-affinity Precipitation Assay (DAPA)

scientific article

Suppression of Inflammasome Activation by IRF8 and IRF4 in cDCs Is Critical for T Cell Priming

scientific article published on 01 May 2020

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share

scientific article

The Promise and Peril of Natural Killer Cell Therapies in Pulmonary Infection

scientific article published on 13 May 2020

The antiprotease SPINK7 serves as an inhibitory checkpoint for esophageal epithelial inflammatory responses

scientific article published on 01 June 2018

The effect of inversion at 8p23 on BLK association with lupus in Caucasian population

scientific article

The genetic etiology of eosinophilic esophagitis

scientific article published on 01 January 2020

The struggle to find reliable results in exome sequencing data: filtering out Mendelian errors

scientific article

The transcription factor ZEB2 drives the formation of age-associated B cells

scientific article published on 25 January 2024

Therapeutic Targeting of Follicular T Cells with Chimeric Antigen Receptor-Expressing Natural Killer Cells

scientific article published on 25 March 2020

Transancestral mapping and genetic load in systemic lupus erythematosus

scientific article published on 17 July 2017

Transcription factors operate across disease loci, with EBNA2 implicated in autoimmunity

scientific article published on 16 April 2018

Twin and family studies reveal strong environmental and weaker genetic cues explaining heritability of eosinophilic esophagitis

scientific article

Using Mendelian inheritance errors as quality control criteria in whole genome sequencing data set.

scientific article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 are associated with gestational duration

article

Variants in the fetal genome near pro-inflammatory cytokine genes on 2q13 associate with gestational duration

scientific article published on 02 September 2019

WAO International Scientific Conference (WISC 2016) Abstracts: Jerusalem, Israel. 6–9 December 2016.

scientific article published on 20 June 2017

Whole exome sequencing for familial bicuspid aortic valve identifies putative variants

scientific article published in August 2014

Whole-exome sequencing uncovers oxidoreductases DHTKD1 and OGDHL as linkers between mitochondrial dysfunction and eosinophilic esophagitis

scientific article published on 19 April 2018

X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome

scientific article published on 29 December 2015

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