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List of works by Calvin Yu-Chian Chen

A Novel Algorithm for Identification of Activated Cryptic 5′ Splice Sites

scientific article published on January 1, 2012

A novel integrated framework and improved methodology of computer-aided drug design.

scientific article published on January 2013

A novel perspective on designing the inhibitor of HER2 receptor

A possible solution for hair loss by inhibiting corticotropin-releasing factor (CRF) receptor from traditional Chinese medicine

scientific article published on 2 September 2013

An investigation of small GTPases in relation to liver tumorigenesis using traditional Chinese medicine.

scientific article

Beware of docking!

scientific article published on 24 December 2014

Chalcone derivatives inhibit human platelet aggregation and inhibit growth in human bladder cancer cells

scientific article

Computational design of apolipoprotein E4 inhibitors for Alzheimer's disease therapy from traditional Chinese medicine.

scientific article

Computational screening and design of traditional Chinese medicine (TCM) to block phosphodiesterase-5.

scientific article published on 8 August 2009

DNA-binding studies of AV-153, an antimutagenic and DNA repair-stimulating derivative of 1,4-dihydropiridine

scientific article published on 10 July 2014

Design of glucagon-like Peptide-1 receptor agonist for diabetes mellitus from traditional chinese medicine.

scientific article

Developing hypothetical inhibition mechanism of novel urea transporter B inhibitor

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Discovery of potent inhibitors for phosphodiesterase 5 by virtual screening and pharmacophore analysis

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Drug design for neuropathic pain regulation from traditional Chinese medicine

scientific article published on 30 January 2013

Drug design of cyclin-dependent kinase 2 inhibitor for melanoma from traditional Chinese medicine.

scientific article

Evaluation of correlation of cell cycle proteins and Ki-67 interaction in paranasal sinus inverted papilloma prognosis and squamous cell carcinoma transformation

scientific article

High performance screening, structural and molecular dynamics analysis to identify H1 inhibitors from TCM Database@Taiwan

scientific article published on October 19, 2011

How to design a drug for the disordered proteins?

scientific article

Identification of Potent EGFR Inhibitors from TCM Database@Taiwan

scientific article published on October 13, 2011

Identification of tyrosinase inhibitors from traditional Chinese medicines for the management of hyperpigmentation

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Identifying HER2 inhibitors from natural products database

scientific article

In Silico Identification of Potent PPAR-γ Agonists from Traditional Chinese Medicine: A Bioactivity Prediction, Virtual Screening, and Molecular Dynamics Study

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In Silico Identification of Potent Pancreatic Triacylglycerol Lipase Inhibitors from Traditional Chinese Medicine

scientific article published on September 6, 2012

In Silico Insight into Potent of Anthocyanin Regulation of FKBP52 to Prevent Alzheimer's Disease.

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In Silico Investigation of Cytochrome P450 2C9 in relation to Aging Using Traditional Chinese Medicine.

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In Silico Investigation of Potential PARP-1 Inhibitors from Traditional Chinese Medicine.

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In silico design for adenosine monophosphate-activated protein kinase agonist from traditional chinese medicine for treatment of metabolic syndromes.

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In silico design of BACE1 inhibitor for Alzheimer's disease by traditional Chinese medicine.

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In silico investigation of potential SRC kinase ligands from traditional Chinese medicine

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In silico investigation of potential TRAF6 inhibitor from traditional Chinese medicine against cancers

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In silico investigation of traditional Chinese medicine compounds to inhibit human histone deacetylase 2 for patients with Alzheimer's disease

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Insight into HIV of IFN-induced myxovirus resistance 2 (MX2) expressed by traditional Chinese medicine

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Insight into molecular dynamics simulation of BRAF(V600E) and potent novel inhibitors for malignant melanoma

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Investigation of anti-infection mechanism of lactoferricin and splunc-1.

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Investigation of the novel lead of melanocortin 1 receptor for pigmentary disorders.

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Lead Screening for Chronic Obstructive Pulmonary Disease of IKK2 Inhibited by Traditional Chinese Medicine

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Lead discovery for Alzheimer's disease related target protein RbAp48 from traditional Chinese medicine.

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Lead screening for CXCR4 of the human HIV infection receptor inhibited by traditional Chinese medicine

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Ligand-based and structure-based investigation for Alzheimer's disease from traditional chinese medicine

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May disordered protein cause serious drug side effect?

scientific article published on 31 October 2013

Mechanism of BAG1 repair on Parkinson’s disease-linked DJ1 mutation

scientific article published on January 1, 2012

Memory enhancement by traditional Chinese medicine?

scientific article published on 19 December 2012

Network pharmacology-based approach of novel traditional Chinese medicine formula for treatment of acute skin inflammation in silico

scientific article published on 14 September 2017

Pharmacological chaperone design for reducing risk factor of Parkinson's disease from traditional chinese medicine

scientific article published on 19 January 2014

Possible inhibitor from traditional Chinese medicine for the β form of calcium-dependent protein kinase type II in the treatment of major depressive disorder

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Potential smoothened inhibitor from traditional Chinese medicine against the disease of diabetes, obesity, and cancer

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Residue-based design of small molecule inhibitor for H1N1, H5N1 and H7N1 mutants

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TCM Database@Taiwan: the world's largest traditional Chinese medicine database for drug screening in silico

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The inhibition of folylpolyglutamate synthetase (folC) in the prevention of drug resistance in Mycobacterium tuberculosis by traditional Chinese medicine

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Traditional Chinese medicine application in HIV: an in silico study

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Traditional Chinese medicine as dual guardians against hypertension and cancer?

scientific article published on 12 June 2012

Treatment of acute lymphoblastic leukemia from traditional chinese medicine

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Treatment of cardiovascular disease by traditional Chinese medicine against pregnane X receptor

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Treatment of rheumatoid arthritis with traditional chinese medicine.

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Two birds with one stone? Possible dual-targeting H1N1 inhibitors from traditional Chinese medicine

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Uroporphyrinogen Decarboxylase as a Potential Target for Specific Components of Traditional Chinese Medicine: A Virtual Screening and Molecular Dynamics Study

scientific article published on November 29, 2012

When modern technology meets ancient traditional chinese medicine

scientific article published on 19 February 2015

iScreen: world's first cloud-computing web server for virtual screening and de novo drug design based on TCM database@Taiwan

scientific article