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List of works by John Tregoning

A "prime-pull" vaccine strategy has a modest effect on local and systemic antibody responses to HIV gp140 in mice

scientific article

A Comparison of Red Fluorescent Proteins to Model DNA Vaccine Expression by Whole Animal In Vivo Imaging

scientific article published on 19 June 2015

A Multi-Component Prime-Boost Vaccination Regimen with a Consensus MOMP Antigen Enhances Chlamydia trachomatis Clearance

scientific article published on 28 April 2016

A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease

scientific article published on May 2016

A Single-Stranded Oligonucleotide Inhibits Toll-Like Receptor 3 Activation and Reduces Influenza A (H1N1) Infection

scientific article published on 12 September 2019

A potential molecular mechanism for hypersensitivity caused by formalin-inactivated vaccines

article

Adjuvanted influenza vaccines

scientific article published on 25 January 2018

Alveolar macrophages are a major determinant of early responses to viral lung infection but do not influence subsequent disease development

scientific article published on 20 February 2008

Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis

scientific article published on 01 December 2019

CD25+ natural regulatory T cells are critical in limiting innate and adaptive immunity and resolving disease following respiratory syncytial virus infection

scientific article

CD71 targeting boosts immunogenicity of sublingually delivered influenza haemagglutinin antigen and protects against viral challenge in mice

scientific article published on 16 April 2016

Childhood infections, the developing immune system, and the origins of asthma.

scientific article published in December 2004

Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy

scientific article published on 24 September 2018

Comparative Metabolomic Sampling of Upper and Lower Airways by Four Different Methods to Identify Biochemicals That May Support Bacterial Growth

scientific article published on 18 December 2018

Comparative analysis of enzymatically produced novel linear DNA constructs with plasmids for use as DNA vaccines

scientific article

DNA Vaccines Encoding Antigen Targeted to MHC Class II Induce Influenza-Specific CD8(+) T Cell Responses, Enabling Faster Resolution of Influenza Disease

scientific article published on 23 August 2016

Dapagliflozin-lowered blood glucose reduces respiratory Pseudomonas aeruginosa infection in diabetic mice

scientific article published on 13 February 2017

Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model

scientific article

Delayed sequelae of neonatal respiratory syncytial virus infection are dependent on cells of the innate immune system

scientific article published on 30 October 2013

Delivery of cytokines by recombinant virus in early life alters the immune response to adult lung infection

scientific article

Development of a custom pentaplex sandwich immunoassay using Protein-G coupled beads for the Luminex® xMAP® platform

scientific article

Differences in nasal immunoglobulin A responses to influenza vaccine strains after live attenuated influenza vaccine (LAIV) immunization in children

scientific article published on 15 November 2019

Differential chemokine expression following respiratory virus infection reflects Th1- or Th2-biased immunopathology.

scientific article

Effect of a Russian-backbone live-attenuated influenza vaccine with an updated pandemic H1N1 strain on shedding and immunogenicity among children in The Gambia: an open-label, observational, phase 4 study

scientific article published on 21 June 2019

Expression of tetanus toxin Fragment C in tobacco chloroplasts

scientific article

From parade ground to PI.

scientific article published in January 2018

Genetic susceptibility to the delayed sequelae of neonatal respiratory syncytial virus infection is MHC dependent.

scientific article published on 4 October 2010

Glucopyranosyl Lipid Adjuvant (GLA), a Synthetic TLR4 agonist, promotes potent systemic and mucosal responses to intranasal immunization with HIVgp140.

scientific article

How will you judge me if not by impact factor? ⬇️

scientific article published in Nature

Identification of novel macrolides with antibacterial, anti-inflammatory and type I and III IFN-augmenting activity in airway epithelium

scientific article published on 25 July 2016

Inflammatory responses to influenza vaccination at the extremes of age.

scientific article published on 4 April 2017

Interferon-Induced Transmembrane Protein 1 Restricts Replication of Viruses That Enter Cells via the Plasma Membrane

scientific article published on 05 March 2019

Interleukin 18 coexpression during respiratory syncytial virus infection results in enhanced disease mediated by natural killer cells

scientific article

Intravaginal immunization using the recombinant HIV-1 clade-C trimeric envelope glycoprotein CN54gp140 formulated within lyophilized solid dosage forms

scientific article

MF59 Mediates Its B Cell Adjuvanticity by Promoting T Follicular Helper Cells and Thus Germinal Center Responses in Adult and Early Life.

scientific article published on 13 April 2015

Metformin reduces airway glucose permeability and hyperglycaemia-induced Staphylococcus aureus load independently of effects on blood glucose

scientific article published on 24 May 2013

Modulating airway glucose to reduce respiratory infections

scientific article published on 07 January 2019

Mucosal application of gp140 encoding DNA polyplexes to different tissues results in altered immunological outcomes in mice.

scientific article

Neonatal antibody responses are attenuated by interferon-γ produced by NK and T cells during RSV infection

scientific article published on 18 March 2013

New advances in the production of edible plant vaccines: chloroplast expression of a tetanus vaccine antigen, TetC.

scientific article published on April 2004

No researcher is too junior to fix science.

scientific article

P02-03. Screening of potential adjuvants for induction of pro-IgA factors.

scientific article

PHiD-CV induces anti-Protein D antibodies but does not augment pulmonary clearance of nontypeable Haemophilus influenzae in mice.

scientific article

Partial Attenuation of Respiratory Syncytial Virus with a Deletion of a Small Hydrophobic Gene Is Associated with Elevated Interleukin-1β Responses

scientific article published on 17 June 2015

Pre-existing influenza specific nasal IgA or nasal viral infection does not affect live attenuated influenza vaccine immunogenicity in children

scientific article published on 13 December 2020

Preexposure to CpG protects against the delayed effects of neonatal respiratory syncytial virus infection

scientific article

Pregnancy has a minimal impact on the acute transcriptional signature to vaccination

scientific article published on 25 March 2020

Protection against tetanus toxin using a plant-based vaccine

scientific article published on 01 April 2005

RSV 2005: Global impact, changing concepts, and new challenges.

scientific article published in January 2005

Recombinant Haemagglutinin Derived From the Ciliated Protozoan Tetrahymena thermophila Is Protective Against Influenza Infection

scientific article published on 13 November 2019

Respiratory Viral Infection Alters the Gut Microbiota by Inducing Inappetence

scientific article published on 18 February 2020

Respiratory syncytial virus after the SARS-CoV-2 pandemic — what next?

scientific article published on 13 July 2022

Respiratory viral infections in infants: causes, clinical symptoms, virology, and immunology

scientific article published in January 2010

Role of CCL11 in eosinophilic lung disease during respiratory syncytial virus infection

scientific article

Role of CCL5 (RANTES) in viral lung disease.

scientific article

Role of airway glucose in bacterial infections in patients with chronic obstructive pulmonary disease.

scientific article published on 13 December 2017

Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses.

scientific article published on 5 December 2017

Ten Simple Rules to becoming a principal investigator

scientific article published on 20 February 2020

The chemokine MIP1alpha/CCL3 determines pathology in primary RSV infection by regulating the balance of T cell populations in the murine lung.

scientific article

The impact of timing of maternal influenza immunization on infant antibody levels at birth

scientific article published on 02 December 2018

The role of T cells in the enhancement of respiratory syncytial virus infection severity during adult reinfection of neonatally sensitized mice

scientific article published on 13 February 2008

The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit

scientific article published on 11 February 2019

Thymic stromal lymphopoietin (TSLP) acts as a potent mucosal adjuvant for HIV-1 gp140 vaccination in mice

scientific article

Use of the Microparticle Nanoscale Silicon Dioxide as an Adjuvant To Boost Vaccine Immune Responses against Influenza Virus in Neonatal Mice.

scientific article published on 24 February 2016

Vaccines for COVID-19

scientific article published on 15 September 2020

Virally delivered cytokines alter the immune response to future lung infections

scientific article

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