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List of works by Xin Wang

5-Fluorouracil derivatives from the sponge Phakellia fusca.

scientific article

A Novel Model of P-Glycoprotein Inhibitor Screening Using Human Small Intestinal Organoids

scientific article published on 22 September 2016

A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice

scientific article

A note on CYP2J2-mediated terfenadine hydroxylation in human liver microsomes

scientific article published on 02 July 2014

A novel biosensor based on intestinal 3D organoids for detecting the function of BCRP.

scientific article

Ailanthone targets p23 to overcome MDV3100 resistance in castration-resistant prostate cancer

scientific article published on 13 December 2016

Assessment of the inhibition risk of shikonin on cytochrome P450 via cocktail inhibition assay

scientific article published on 20 September 2017

CRISPR knockout rat cytochrome P450 3A1/2 model for advancing drug metabolism and pharmacokinetics research

scientific article published on 20 February 2017

Characterization of in vitro Mrp2 transporter model based on intestinal organoids

scientific article published on 23 August 2019

Comprehensive assessment of Cucurbitacin E related hepatotoxicity and drug-drug interactions involving CYP3A and P-glycoprotein

scientific article published on 9 January 2017

Design and optimization of novel hydroxamate-based histone deacetylase inhibitors of Bis-substituted aromatic amides bearing potent activities against tumor growth and metastasis.

scientific article

Design and optimization of the cocktail assay for rapid assessment of the activity of UGT enzymes in human and rat liver microsomes

scientific article published on 20 July 2018

Development and Characterization of MDR1 (Mdr1a/b) CRISPR/Cas9 Knockout Rat Model

scientific article published on 26 November 2018

Development of a validated LC-MS/MS method for the determination of ailanthone in rat plasma with application to pharmacokinetic study

scientific article published on 31 October 2014

Effects of Salvia miltiorrhiza extract on the liver CYP3A activity in humans and rats

scientific article published on 21 March 2011

Effects of cucurbitacin e, a tetracyclic triterpene compound from Cucurbitaceae, on the pharmacokinetics and pharmacodynamics of warfarin in rats.

scientific article published on 13 October 2014

Effects of major tanshinones isolated from Danshen (Salvia miltiorrhiza) on rat CYP1A2 expression and metabolism of model CYP1A2 probe substrates.

scientific article published on 28 April 2009

Effects of the aqueous extract from Salvia miltiorrhiza Bunge on caffeine pharmacokinetics and liver microsomal CYP1A2 activity in humans and rats.

scientific article published on August 2010

Evaluation of enzyme inhibition kinetics in drug-drug interactions

scientific article published on 23 October 2014

Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS/MS and cocktail approach

scientific article published on 22 June 2016

Evaluation of the inhibition risk of shikonin on human and rat UDP-glucuronosyltransferases (UGT) through the cocktail approach

scientific article published on 23 May 2019

Generation and Characterization of Cytochrome P450 2J3/10 CRISPR/Cas9 Knockout Rat Model

scientific article published on 01 September 2020

In vitro and in vivo evaluation of cucurbitacin E on rat hepatic CYP2C11 expression and activity using LC-MS/MS.

scientific article

Inhibitory effect of tanshinones on rat CYP3A2 and CYP2C11 activity and its structure-activity relationship

scientific article published on 22 January 2011

Inhibitory effects of celastrol on rat liver cytochrome P450 1A2, 2C11, 2D6, 2E1 and 3A2 activity.

scientific article

Investigation of cytochrome P450 1A2 and 3A inhibitory properties of Danshen tincture

scientific article

Investigation of cytochrome P450 inhibitory properties of maslinic acid, a bioactive compound from Olea europaea L., and its structure-activity relationship

scientific article published on 23 October 2014

LG308, a Novel Synthetic Compound with Antimicrotubule Activity in Prostate Cancer Cells, Exerts Effective Antitumor Activity.

scientific article published on 16 September 2015

Measurement of Rhodamine 123 in Three-Dimensional Organoids: A Novel Model for P-Glycoprotein Inhibitor Screening

scientific article published on 6 April 2016

Modification and Biological Evaluation of a Series of 1,5-Diaryl-1,2,4-triazole Compounds as Novel Agents against Pancreatic Cancer Metastasis through Targeting Myoferlin

scientific article published on 08 May 2019

New insights into the androgen biotransformation in prostate cancer: A regulatory network among androgen, androgen receptors and UGTs

scientific article published on 26 February 2016

Organic anion transport polypeptide 1b2 selectively affects the pharmacokinetic interaction between paclitaxel and sorafenib in rats

scientific article published on 19 August 2019

Pharmacokinetic interaction studies of tanshinones with tolbutamide, a model CYP2C11 probe substrate, using liver microsomes, primary hepatocytes and in vivo in the rat.

scientific article published on 12 August 2009

Pharmacokinetics of metronidazole in pregnant patients with bacterial vaginosis.

scientific article

Plant natural product plumbagin presents potent inhibitory effect on human cytochrome P450 2J2 enzyme

scientific article published on 26 December 2017

Quantification of nucleotides and their sugar conjugates in biological samples: Purposes, instruments and applications

scientific article published on 08 June 2018

Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer

scientific article published on 07 December 2020

Systemic regulation of L-carnitine in nutritional metabolism in zebrafish, Danio rerio

scientific article published on 19 January 2017

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