List of works - Victor Faundez

A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles.

scientific article

A comprehensive strategy to identify stoichiometric membrane protein interactomes.

scientific article

A function for the AP3 coat complex in synaptic vesicle formation from endosomes

scientific journal article

A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia

scientific article

ADP ribosylation factor 1 is required for synaptic vesicle budding in PC12 cells.

scientific article

AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells

scientific article

Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear

scientific article published on 03 July 2019

An AP-3-dependent mechanism drives synaptic-like microvesicle biogenesis in pancreatic islet beta-cells.

scientific article

An MBoC Favorite: Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons.

scientific article published in June 2012

Anatomical localization of Cav3.1 calcium channels and electrophysiological effects of T-type calcium channel blockade in the motor thalamus of MPTP-treated monkeys

scientific article

Axons Sprout and Microtubules Increase After Local Inhibition of RNA Synthesis, and Microtubules Decrease after Inhibition of Protein Synthesis: A Morphometric Study of Rat Sural Nerves

scientific article published on 01 October 1991

BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes

scientific article

BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes

scientific journal article

BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia.

scientific article published on 2 June 2017

Calibers and microtubules of nerve fibers: differential effect of undernutrition in developing and adult rats

scientific article

Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene.

scientific article published on 26 April 2011

Cellular and molecular mechanisms of neurodevelopmental disorders

scientific article published on 22 February 2017

Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells

scientific article

Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis.

scientific article

Ciprofibrate, a carcinogenic peroxisome proliferator, increases the phosphorylation of epidermal-growth-factor receptor in isolated rat hepatocytes

scientific article published on 01 August 1993

Cross-species analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion

scientific article published in 2023

Desmosome assembly and disassembly are membrane raft-dependent

scientific article (publication date: 2014)

Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus.

scientific article published on 10 March 2017

EMBO workshop al fin del mundo: a meeting on membrane trafficking and its implication for polarity and diseases

scientific article published on 01 July 2015

Endosomal recycling regulates Anthrax Toxin Receptor 1/Tumor Endothelial Marker 8-dependent cell spreading.

scientific article

Epidermal growth factor receptor in synaptic fractions of the rat central nervous system

scientific journal article

FMRP attenuates activity dependent modifications in the mitochondrial proteome

scientific article published on 30 April 2021

Gene dosage in the dysbindin schizophrenia susceptibility network differentially affect synaptic function and plasticity

scientific article

Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.

scientific article

Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content

scientific article published on 17 November 2020

Hermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampus

scientific journal article

Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.

scientific article published on 14 November 2008

Identification of the Interactome of a Palmitoylated Membrane Protein, Phosphatidylinositol 4-Kinase Type II Alpha.

scientific article published in January 2016

Integrative biological simulation praxis: Considerations from physics, philosophy, and data/model curation practices.

scientific article published on 29 November 2017

Intermediate filaments and vesicular membrane traffic: the odd couple's first dance?

scientific article

Intracellular chloride channels: determinants of function in the endosomal pathway.

scientific article published on 11 May 2004

Isolation of labile multi-protein complexes by in vivo controlled cellular cross-linking and immuno-magnetic affinity chromatography

scientific article

Isolation of synaptic vesicles

scientific article published in December 2004

MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons.

scientific article

Mechanisms of VE-cadherin processing and degradation in microvascular endothelial cells.

scientific article published on 6 March 2003

Metazoan cell biology of the HOPS tethering complex

scientific article

Microtubules and calibers in developing axons.

scientific article

Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus

scientific article published on 14 July 2021

Molecular Systems Biology of Neurodevelopmental Disorders, Rett Syndrome as an Archetype

scientific article published on 17 July 2019

Molecular basis of neurodegeneration and neurodevelopmental defects in Menkes disease

scientific article

Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes.

scientific article

Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes.

scientific article

Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes

scientific article

Neuronal and immune synapses on the move at traffic

scientific article published on 01 March 2015

Neuronal and non-neuronal functions of the AP-3 sorting machinery

scientific article published on February 2007

Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor.

scientific article

Neuronal zinc stores are modulated by non-steroidal anti-inflammatory drugs: an optical analysis in cultured hippocampal neurons

scientific article published on 20 October 2005

On the endosomal function and gene nomenclature of human SPE-39.

scientific article published in March 2011

Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism

scientific article

Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic

scientific journal article

Phosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesicles

scientific article

Presynaptic membrane retrieval and endosome biology: defining molecularly heterogeneous synaptic vesicles

scientific article published on October 2013

Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1.

scientific article published in March 2012

Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees

scientific article

Ratiometric two-photon microscopy reveals attomolar copper buffering in normal and Menkes mutant cells

scientific article published on 03 June 2019

Reconstitution of synaptic vesicle biogenesis from PC12 cell membranes

scientific article

Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles

scientific journal article

SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity

scientific article

SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery

scientific article

Saccharomyces cerevisiae Npc2p is a functionally conserved homologue of the human Niemann-Pick disease type C 2 protein, hNPC2.

scientific article

Schizophrenia: the "BLOC" may be in the endosomes

scientific article published on 20 October 2009

Sex-dimorphic effects of biogenesis of lysosome-related organelles complex-1 deficiency on mouse perinatal brain development

scientific article published on 20 May 2020

Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior

scientific article published on 04 March 2019

Teaching resources. Chloride concentration and pH along the endosomal pathway

scientific article published on 18 May 2004

The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform

scientific article

The Endolysosomal System and Proteostasis: From Development to Degeneration

scientific article published on 01 October 2018

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin

scientific article published on 22 September 2016

The N-ethylmaleimide-sensitive factor and dysbindin interact to modulate synaptic plasticity.

scientific article published on May 2015

The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse

scientific article published on December 2016

The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors.

scientific article

The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes.

scientific article

The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3.

scientific article

Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathway

scientific article published on 14 March 2011

Trafficking mechanisms of P-type ATPase copper transporters

scientific article published on 29 March 2019

Translating molecular advances in Down syndrome and Fragile X syndrome into therapies

scientific article published on 07 June 2018

Vesicles derived via AP-3-dependent recycling contribute to asynchronous release and influence information transfer

scientific article

Vglut1 and ZnT3 co-targeting mechanisms regulate vesicular zinc stores in PC12 cells

scientific journal article

p120-Catenin regulates clathrin-dependent endocytosis of VE-cadherin

scientific article

p120-catenin binding masks an endocytic signal conserved in classical cadherins.

scientific article

List of works by Victor Faundez

A biochemical and functional protein complex involving dopamine synthesis and transport into synaptic vesicles.

A comprehensive strategy to identify stoichiometric membrane protein interactomes.

A function for the AP3 coat complex in synaptic vesicle formation from endosomes

A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia

ADP ribosylation factor 1 is required for synaptic vesicle budding in PC12 cells.

AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells

Adaptor protein-3 complex is required for Vangl2 trafficking and planar cell polarity of the inner ear

An AP-3-dependent mechanism drives synaptic-like microvesicle biogenesis in pancreatic islet beta-cells.

An MBoC Favorite: Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons.

Anatomical localization of Cav3.1 calcium channels and electrophysiological effects of T-type calcium channel blockade in the motor thalamus of MPTP-treated monkeys

Axons Sprout and Microtubules Increase After Local Inhibition of RNA Synthesis, and Microtubules Decrease after Inhibition of Protein Synthesis: A Morphometric Study of Rat Sural Nerves

BLOC-1 Brings Together the Actin and Microtubule Cytoskeletons to Generate Recycling Endosomes

BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes

BLOC-1 is required for selective membrane protein trafficking from endosomes to primary cilia.

Calibers and microtubules of nerve fibers: differential effect of undernutrition in developing and adult rats

Cell biology of the BLOC-1 complex subunit dysbindin, a schizophrenia susceptibility gene.

Cellular and molecular mechanisms of neurodevelopmental disorders

Cellular levels of p120 catenin function as a set point for cadherin expression levels in microvascular endothelial cells

Chemical-genetic disruption of clathrin function spares adaptor complex 3-dependent endosome vesicle biogenesis.

Ciprofibrate, a carcinogenic peroxisome proliferator, increases the phosphorylation of epidermal-growth-factor receptor in isolated rat hepatocytes

Cross-species analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion

Desmosome assembly and disassembly are membrane raft-dependent

Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus.

EMBO workshop al fin del mundo: a meeting on membrane trafficking and its implication for polarity and diseases

Endosomal recycling regulates Anthrax Toxin Receptor 1/Tumor Endothelial Marker 8-dependent cell spreading.

Epidermal growth factor receptor in synaptic fractions of the rat central nervous system

FMRP attenuates activity dependent modifications in the mitochondrial proteome

Gene dosage in the dysbindin schizophrenia susceptibility network differentially affect synaptic function and plasticity

Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.

Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content

Hermansky-Pudlak protein complexes, AP-3 and BLOC-1, differentially regulate presynaptic composition in the striatum and hippocampus

Hermansky-Pudlak syndrome protein complexes associate with phosphatidylinositol 4-kinase type II alpha in neuronal and non-neuronal cells.

Identification of the Interactome of a Palmitoylated Membrane Protein, Phosphatidylinositol 4-Kinase Type II Alpha.

Integrative biological simulation praxis: Considerations from physics, philosophy, and data/model curation practices.

Intermediate filaments and vesicular membrane traffic: the odd couple's first dance?

Intracellular chloride channels: determinants of function in the endosomal pathway.

Isolation of labile multi-protein complexes by in vivo controlled cellular cross-linking and immuno-magnetic affinity chromatography

Isolation of synaptic vesicles

MeCP2 regulates the synaptic expression of a Dysbindin-BLOC-1 network component in mouse brain and human induced pluripotent stem cell-derived neurons.

Mechanisms of VE-cadherin processing and degradation in microvascular endothelial cells.

Metazoan cell biology of the HOPS tethering complex

Microtubules and calibers in developing axons.

Mitochondrial Proteostasis Requires Genes Encoded in a Neurodevelopmental Syndrome Locus

Molecular Systems Biology of Neurodevelopmental Disorders, Rett Syndrome as an Archetype

Molecular basis of neurodegeneration and neurodevelopmental defects in Menkes disease

Mutations in the BLOC-1 subunits dysbindin and muted generate divergent and dosage-dependent phenotypes.

Neurodevelopmental disease mechanisms, primary cilia, and endosomes converge on the BLOC-1 and BORC complexes.

Neurodevelopmental disorders: mechanisms and boundary definitions from genomes, interactomes and proteomes

Neuronal and immune synapses on the move at traffic

Neuronal and non-neuronal functions of the AP-3 sorting machinery

Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor.

Neuronal zinc stores are modulated by non-steroidal anti-inflammatory drugs: an optical analysis in cultured hippocampal neurons

On the endosomal function and gene nomenclature of human SPE-39.

Pemphigus vulgaris IgG-induced desmoglein-3 endocytosis and desmosomal disassembly are mediated by a clathrin- and dynamin-independent mechanism

Phosphatidylinositol-4-kinase type II alpha contains an AP-3-sorting motif and a kinase domain that are both required for endosome traffic

Phosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesicles

Presynaptic membrane retrieval and endosome biology: defining molecularly heterogeneous synaptic vesicles

Quantitative proteomic and genetic analyses of the schizophrenia susceptibility factor dysbindin identify novel roles of the biogenesis of lysosome-related organelles complex 1.

Rare Disease Mechanisms Identified by Genealogical Proteomics of Copper Homeostasis Mutant Pedigrees

Ratiometric two-photon microscopy reveals attomolar copper buffering in normal and Menkes mutant cells

Reconstitution of synaptic vesicle biogenesis from PC12 cell membranes

Roles of BLOC-1 and adaptor protein-3 complexes in cargo sorting to synaptic vesicles

SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity

SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery

Saccharomyces cerevisiae Npc2p is a functionally conserved homologue of the human Niemann-Pick disease type C 2 protein, hNPC2.

Schizophrenia: the "BLOC" may be in the endosomes

Sex-dimorphic effects of biogenesis of lysosome-related organelles complex-1 deficiency on mouse perinatal brain development

Systems Analysis of the 22q11.2 Microdeletion Syndrome Converges on a Mitochondrial Interactome Necessary for Synapse Function and Behavior

Teaching resources. Chloride concentration and pH along the endosomal pathway

The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform

The Endolysosomal System and Proteostasis: From Development to Degeneration

The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin

The N-ethylmaleimide-sensitive factor and dysbindin interact to modulate synaptic plasticity.

The Proteome of BLOC-1 Genetic Defects Identifies the Arp2/3 Actin Polymerization Complex to Function Downstream of the Schizophrenia Susceptibility Factor Dysbindin at the Synapse

The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors.

The neuronal form of adaptor protein-3 is required for synaptic vesicle formation from endosomes.

The subcellular localization of the Niemann-Pick Type C proteins depends on the adaptor complex AP-3.

Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathway

Trafficking mechanisms of P-type ATPase copper transporters