List of works - Dennis G. Hall

3-Boronoacrolein as an exceptional heterodiene in the highly enantio- and diastereoselective Cr(III)-catalyzed three-component [4+2]/allylboration

scientific article published in August 2003

A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepacia

scientific article

A mild and general solid-phase method for the synthesis of chiral polyamines. Solution studies on the cleavage of borane-amine intermediates from the reduction of secondary amides.

scientific article

A surprising substituent effect provides a superior boronic acid catalyst for mild and metal-free direct Friedel-Crafts alkylations and prenylations of neutral arenes

scientific article published on 10 February 2015

A three-component reaction for diversity-oriented synthesis of polysubstituted piperidines: solution and solid-phase optimization of the first tandem aza[4+2]/allylboration

scientific article published in January 2003

Alpha-hydroxyalkyl heterocycles via chiral allylic boronates: Pd-catalyzed borylation leading to a formal enantioselective isomerization of allylic ether and amine.

scientific article published in July 2009

An improved class of sugar-binding boronic acids, soluble and capable of complexing glycosides in neutral water

scientific article published on 01 April 2006

Boronic Acids as Bioorthogonal Probes for Site-Selective Labeling of Proteins

scientific article published on 23 August 2018

Boronic acid catalysis as a mild and versatile strategy for direct carbo- and heterocyclizations of free allylic alcohols

scientific article published on 15 May 2012

Boronic acid catalysis for mild and selective [3+2] dipolar cycloadditions to unsaturated carboxylic acids.

scientific article published in May 2010

Brønsted acid-catalyzed allylboration: short and stereodivergent synthesis of all four eupomatilone diastereomers with crystallographic assignments

scientific article

Catalytic asymmetric synthesis of a potent thiomarinol antibiotic.

scientific article

Catalytic asymmetric synthesis of palmerolide A via organoboron methodology

scientific article published on 01 October 2009

Catalytic enantioselective allyl- and crotylboration of aldehydes using chiral diol x SnCl4 complexes. optimization, substrate scope and mechanistic investigations

scientific article published on 7 June 2008

Catalytic enantioselective and catalyst-controlled diastereofacial-selective additions of allyl- and crotylboronates to aldehydes using chiral Brønsted acids

scientific article published in April 2006

Catalytic enantioselective diversity-oriented synthesis of a small library of polyhydroxylated pyrans inspired from thiomarinol antibiotics

scientific article

Catalytic enantioselective preparation of alpha-substituted allylboronates: one-pot addition to functionalized aldehydes and a route to chiral allylic trifluoroborate reagents

scientific article published on 01 January 2007

Catalytic enantioselective three-component hetero-[4+2] cycloaddition/allylboration approach to alpha-hydroxyalkyl pyrans: scope, limitations, and mechanistic proposal

scientific article published in April 2006

Combinatorial [correction of Combinational] chemistry gives cell biology some muscle

scientific article published on 01 March 2000

Combinatorial approach to selective multivalent ion pairing in mixed aqueous-organic media using bead-supported libraries of unnatural polyamines.

scientific article

Concise synthesis and antimalarial activity of all four mefloquine stereoisomers using a highly enantioselective catalytic borylative alkene isomerization

scientific article published on July 2013

Conjugation of quinones with natural polyamines: toward an expanded antitrypanosomatid profile

scientific article

Design of a nonreductive method for chemoselective cleavage of hydrazines in the presence of unsaturations: application to a stereoconvergent three-component synthesis of (-)-methyl palustramate

scientific article published in November 2004

Design, synthesis and structure of a frustrated benzoxaborole and its applications in the complexation of amines, amino acids, and protein modification

scientific article published on 27 April 2020

Design, synthesis, and screening of a library of peptidyl bis(boroxoles) as oligosaccharide receptors in water: identification of a receptor for the tumor marker TF-antigen disaccharide

scientific article

Diastereocontrolled Monoprotodeboronation of β-Sulfinimido gem-Bis(boronates): A General and Stereoselective Route to α,β-Disubstituted β-Aminoalkylboronates

scientific article published on 18 July 2018

Direct amidation of carboxylic acids catalyzed by ortho-iodo arylboronic acids: catalyst optimization, scope, and preliminary mechanistic study supporting a peculiar halogen acceleration effect

scientific article published on 26 September 2012

Direct and waste-free amidations and cycloadditions by organocatalytic activation of carboxylic acids at room temperature

scientific article published on 01 January 2008

Direct mono-N-methylation of solid-supported amino acids: a useful application of the Matteson rearrangement of alpha-aminoalkylboronic esters

scientific article published on 01 May 2001

Diversity-oriented synthesis and preliminary biological screening of highly substituted five-membered lactones and lactams originating from an allyboration of aldehydes and imines

scientific article

Dramatic rate enhancement with preservation of stereospecificity in the first metal-catalyzed additions of allylboronates

scientific article published in October 2002

Effect of additives on the stereochemical integrity and reactivity of alpha-alkoxycarbonyl alkenylcopper intermediates. Optimal conditions for the synthesis of isomerically pure tetrasubstituted alkenes

scientific article published in July 2003

Enantioselective preparation and chemoselective cross-coupling of 1,1-diboron compounds ⬇️

scientific article published on September 25, 2011

Fast and Tight Boronate Formation for Click Bioorthogonal Conjugation

scientific article

Fast and Tight Boronate Formation for Click Bioorthogonal Conjugation

scientific article published in 2016

Fragmentation enables complexity in the first total synthesis of vinigrol

scientific article published on 01 March 2010

General solid-phase approach to the synthesis of chiral triazacycloalkane ligands with stereogenic backbone substituents

scientific article published on 01 July 2002

High-Throughput Ligand Screening Enables the Enantioselective Conjugate Borylation of Cyclobutenones to Access Synthetically Versatile Tertiary Cyclobutylboronates

scientific article published on 31 October 2019

Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase

scientific article published on 22 September 2009

In Situ Forming, Dual-Crosslink Network, Self-Healing Hydrogel Enabled by a Bioorthogonal Nopoldiol–Benzoxaborolate Click Reaction with a Wide pH Range

scientific article published in 2019

Injectable Self-Healing Zwitterionic Hydrogels Based on Dynamic Benzoxaborole-Sugar Interactions with Tunable Mechanical Properties

scientific article published on 16 January 2018

Investigation of nonspecific effects of different dyes in the screening of labeled carbohydrates against immobilized proteins

scientific article

Label-free detection of enhanced saccharide binding at pH 7.4 to nanoparticulate benzoboroxole based receptor units

scientific article published on 01 November 2011

Lewis acid catalyzed allylboration: discovery, optimization, and application to the formation of stereogenic quaternary carbon centers

scientific article published on 01 June 2004

Lewis acids catalyze the addition of allylboronates to aldehydes by electrophilic activation of the dioxaborolane in a closed transition structure

scientific article published in April 2004

Mechanism of action of an imidopiperidine inhibitor of human polynucleotide kinase/phosphatase

scientific article

Mild Oxidative Cleavage of Borane-Amine Adducts from Amide Reductions: Efficient Solution- and Solid-Phase Synthesis of N-Alkylamino Acids and Chiral Oligoamines

scientific article published on 01 February 1999

Mild silver(I)-mediated regioselective iodination and bromination of arylboronic acids

scientific article published on 01 June 2010

Multiresponsive and Self-Healing Hydrogel via Formation of Polymer-Nanogel Interfacial Dynamic Benzoxaborole Esters at Physiological pH

scientific article published on 15 November 2019

Multistep phase-switch synthesis by using liquid-liquid partitioning of boronic acids: productive tags with an expanded repertoire of compatible reactions

scientific article published on 9 February 2010

N,N-Diethanolaminomethyl Polystyrene: An Efficient Solid Support to Immobilize Boronic Acids

scientific article published on 01 October 1999

Nanoencapsulation of Novel Inhibitors of PNKP for Selective Sensitization to Ionizing Radiation and Irinotecan and Induction of Synthetic Lethality.

scientific article published on 24 April 2018

Novel isomerically pure tetrasubstituted allylboronates: stereocontrolled synthesis of alpha-exomethylene gamma-lactones as aldol-like adducts with a stereogenic quaternary carbon center

scientific article published on 01 February 2002

Optimization of Reaction and Substrate Activation in the Stereoselective Cross-Coupling of Chiral 3,3-Diboronyl Amides

scientific article published on 01 July 2015

Optimization of three- and four-component reactions for polysubstituted piperidines: application to the synthesis and preliminary biological screening of a prototype library

scientific article

Phase-switch synthesis with boronic acids as productive tags

scientific article published on 01 March 2007

Practical and efficient multigram preparation of a camphor-derived diol for the enantioselective Lewis acid catalyzed allylboration of aldehydes

scientific article published in May 2005

Rationally improved chiral Brønsted acid for catalytic enantioselective allylboration of aldehydes with an expanded reagent scope.

scientific article published in June 2009

Reaction Optimization, Scalability, and Mechanistic Insight on the Catalytic Enantioselective Desymmetrization of 1,1-Diborylalkanes via Suzuki-Miyaura Cross-Coupling

scientific article published on 01 April 2015

Recent advances in the activation of boron and silicon reagents for stereocontrolled allylation reactions

scientific article published in October 2003

Resin-to-resin suzuki coupling of solid supported arylboronic acids

scientific article published on 01 May 2000

Ring Structure and Aromatic Substituent Effects on the pK a of the Benzoxaborole Pharmacophore

scientific article

Scandium-catalyzed allylboration of aldehydes as a practical method for highly diastereo- and enantioselective construction of homoallylic alcohols

scientific article published in August 2003

Scope and Mechanism of a True Organocatalytic Beckmann Rearrangement with a Boronic Acid/Perfluoropinacol System under Ambient Conditions

scientific article published on 22 March 2018

Screening of a combinatorial library of synthetic polyamines displaying selectivity in multiple ion-pairing interactions with model polyanionic compounds in aqueous organic solutions

scientific article

Simple, Stable, and Versatile Double-Allylation Reagents for the Stereoselective Preparation of Skeletally Diverse Compounds

scientific article published on 22 February 2007

Solid phase syntheses of polyamine toxins HO-416b and PhTX-433. Use of an efficient polyamide reduction strategy that facilitates access to branched analogues

scientific article published in June 2000

Solid-phase synthesis of cleavable N-arylmaleimides: applications in 1,3-dipolar cycloaddition and in thiol scavenging

scientific article published on 01 November 2001

Solution- and solid-phase strategies for the design, synthesis, and screening of libraries based on natural product templates: a comprehensive survey.

scientific article

Spatiotemporal Control of Synergistic Gel Disintegration Consisting of Boroxole- and Glyco-Based Polymers via Photoinduced Proton Transfer

scientific article published on 29 September 2014

Stereoselective and Regiodivergent Allylic Suzuki-Miyaura Cross-Coupling of 2-Ethoxydihydropyranyl Boronates: Synthesis and Confirmation of Absolute Stereochemistry of Diospongin B

scientific article published on 20 August 2015

Stereoselective preparation of β-aryl-β-boronyl enoates and their copper-catalyzed enantioselective conjugate reduction

scientific article published on 15 August 2012

Synergic "Click" Boronate/Thiosemicarbazone System for Fast and Irreversible Bioorthogonal Conjugation in Live Cells.

scientific article published on 11 September 2017

Synthesis and high performance liquid chromatography/electrospray mass spectrometry single-bead decoding of split-pool structural libraries of polyamines supported on polystyrene and polystyrene/ethylene glycol resins.

scientific article

Synthesis and preliminary antibacterial evaluation of simplified thiomarinol analogs

scientific article published on 9 January 2008

Synthesis of chiral heterocycles by ligand-controlled regiodivergent and enantiospecific Suzuki Miyaura cross-coupling.

scientific article published on 18 November 2014

Synthesis of the non-peptidic snail toxin 6-bromo-2-mercaptotryptamine dimer (BrMT)(2), its lower and higher thio homologs and their ability to modulate potassium ion channels

scientific article

Tandem Aza

scientific article published on 01 November 2000

Three-component sequential aza[4+2] cycloaddition/allylboration/retro-sulfinyl-ene reaction: a new stereocontrolled entry to palustrine alkaloids and other 2,6-disubstituted piperidines

scientific article published on 01 April 2004

Total synthesis of (+)-chinensiolide B via tandem allylboration/lactonization

scientific article published in February 2010

Triflic acid-catalyzed additions of 2-alkoxycarbonyl allylboronates to aldehydes. Study of scope and mechanistic investigation of the reaction stereochemistry

scientific article published on 01 February 2007

Universal solid-phase approach for the immobilization, derivatization, and resin-to-resin transfer reactions of boronic acids.

scientific article

Unsymmetrical Diarylmethanes by Ferroceniumboronic Acid Catalyzed Direct Friedel-Crafts Reactions with Deactivated Benzylic Alcohols: Enhanced Reactivity due to Ion-Pairing Effects

scientific article

Wanted: new multicomponent reactions for generating libraries of polycyclic natural products

scientific article published in June 2005

List of works by Dennis G. Hall

3-Boronoacrolein as an exceptional heterodiene in the highly enantio- and diastereoselective Cr(III)-catalyzed three-component [4+2]/allylboration

A Pipeline for Screening Small Molecules with Growth Inhibitory Activity against Burkholderia cenocepacia

A mild and general solid-phase method for the synthesis of chiral polyamines. Solution studies on the cleavage of borane-amine intermediates from the reduction of secondary amides.

A surprising substituent effect provides a superior boronic acid catalyst for mild and metal-free direct Friedel-Crafts alkylations and prenylations of neutral arenes

A three-component reaction for diversity-oriented synthesis of polysubstituted piperidines: solution and solid-phase optimization of the first tandem aza[4+2]/allylboration

Alpha-hydroxyalkyl heterocycles via chiral allylic boronates: Pd-catalyzed borylation leading to a formal enantioselective isomerization of allylic ether and amine.

An improved class of sugar-binding boronic acids, soluble and capable of complexing glycosides in neutral water

Boronic Acids as Bioorthogonal Probes for Site-Selective Labeling of Proteins

Boronic acid catalysis as a mild and versatile strategy for direct carbo- and heterocyclizations of free allylic alcohols

Boronic acid catalysis for mild and selective [3+2] dipolar cycloadditions to unsaturated carboxylic acids.

Brønsted acid-catalyzed allylboration: short and stereodivergent synthesis of all four eupomatilone diastereomers with crystallographic assignments

Catalytic asymmetric synthesis of a potent thiomarinol antibiotic.

Catalytic asymmetric synthesis of palmerolide A via organoboron methodology

Catalytic enantioselective allyl- and crotylboration of aldehydes using chiral diol x SnCl4 complexes. optimization, substrate scope and mechanistic investigations

Catalytic enantioselective and catalyst-controlled diastereofacial-selective additions of allyl- and crotylboronates to aldehydes using chiral Brønsted acids

Catalytic enantioselective diversity-oriented synthesis of a small library of polyhydroxylated pyrans inspired from thiomarinol antibiotics

Catalytic enantioselective preparation of alpha-substituted allylboronates: one-pot addition to functionalized aldehydes and a route to chiral allylic trifluoroborate reagents

Catalytic enantioselective three-component hetero-[4+2] cycloaddition/allylboration approach to alpha-hydroxyalkyl pyrans: scope, limitations, and mechanistic proposal

Combinatorial [correction of Combinational] chemistry gives cell biology some muscle

Combinatorial approach to selective multivalent ion pairing in mixed aqueous-organic media using bead-supported libraries of unnatural polyamines.

Concise synthesis and antimalarial activity of all four mefloquine stereoisomers using a highly enantioselective catalytic borylative alkene isomerization

Conjugation of quinones with natural polyamines: toward an expanded antitrypanosomatid profile

Design of a nonreductive method for chemoselective cleavage of hydrazines in the presence of unsaturations: application to a stereoconvergent three-component synthesis of (-)-methyl palustramate

Design, synthesis and structure of a frustrated benzoxaborole and its applications in the complexation of amines, amino acids, and protein modification

Design, synthesis, and screening of a library of peptidyl bis(boroxoles) as oligosaccharide receptors in water: identification of a receptor for the tumor marker TF-antigen disaccharide

Diastereocontrolled Monoprotodeboronation of β-Sulfinimido gem-Bis(boronates): A General and Stereoselective Route to α,β-Disubstituted β-Aminoalkylboronates

Direct amidation of carboxylic acids catalyzed by ortho-iodo arylboronic acids: catalyst optimization, scope, and preliminary mechanistic study supporting a peculiar halogen acceleration effect

Direct and waste-free amidations and cycloadditions by organocatalytic activation of carboxylic acids at room temperature

Direct mono-N-methylation of solid-supported amino acids: a useful application of the Matteson rearrangement of alpha-aminoalkylboronic esters

Diversity-oriented synthesis and preliminary biological screening of highly substituted five-membered lactones and lactams originating from an allyboration of aldehydes and imines

Dramatic rate enhancement with preservation of stereospecificity in the first metal-catalyzed additions of allylboronates

Effect of additives on the stereochemical integrity and reactivity of alpha-alkoxycarbonyl alkenylcopper intermediates. Optimal conditions for the synthesis of isomerically pure tetrasubstituted alkenes

Enantioselective preparation and chemoselective cross-coupling of 1,1-diboron compounds ⬇️

Fast and Tight Boronate Formation for Click Bioorthogonal Conjugation

Fast and Tight Boronate Formation for Click Bioorthogonal Conjugation

Fragmentation enables complexity in the first total synthesis of vinigrol

General solid-phase approach to the synthesis of chiral triazacycloalkane ligands with stereogenic backbone substituents

High-Throughput Ligand Screening Enables the Enantioselective Conjugate Borylation of Cyclobutenones to Access Synthetically Versatile Tertiary Cyclobutylboronates

Identification of a small molecule inhibitor of the human DNA repair enzyme polynucleotide kinase/phosphatase

In Situ Forming, Dual-Crosslink Network, Self-Healing Hydrogel Enabled by a Bioorthogonal Nopoldiol–Benzoxaborolate Click Reaction with a Wide pH Range

Injectable Self-Healing Zwitterionic Hydrogels Based on Dynamic Benzoxaborole-Sugar Interactions with Tunable Mechanical Properties

Investigation of nonspecific effects of different dyes in the screening of labeled carbohydrates against immobilized proteins

Label-free detection of enhanced saccharide binding at pH 7.4 to nanoparticulate benzoboroxole based receptor units

Lewis acid catalyzed allylboration: discovery, optimization, and application to the formation of stereogenic quaternary carbon centers

Lewis acids catalyze the addition of allylboronates to aldehydes by electrophilic activation of the dioxaborolane in a closed transition structure

Mechanism of action of an imidopiperidine inhibitor of human polynucleotide kinase/phosphatase

Mild Oxidative Cleavage of Borane-Amine Adducts from Amide Reductions: Efficient Solution- and Solid-Phase Synthesis of N-Alkylamino Acids and Chiral Oligoamines

Mild silver(I)-mediated regioselective iodination and bromination of arylboronic acids

Multiresponsive and Self-Healing Hydrogel via Formation of Polymer-Nanogel Interfacial Dynamic Benzoxaborole Esters at Physiological pH

Multistep phase-switch synthesis by using liquid-liquid partitioning of boronic acids: productive tags with an expanded repertoire of compatible reactions

N,N-Diethanolaminomethyl Polystyrene: An Efficient Solid Support to Immobilize Boronic Acids

Nanoencapsulation of Novel Inhibitors of PNKP for Selective Sensitization to Ionizing Radiation and Irinotecan and Induction of Synthetic Lethality.

Novel isomerically pure tetrasubstituted allylboronates: stereocontrolled synthesis of alpha-exomethylene gamma-lactones as aldol-like adducts with a stereogenic quaternary carbon center

Optimization of Reaction and Substrate Activation in the Stereoselective Cross-Coupling of Chiral 3,3-Diboronyl Amides

Optimization of three- and four-component reactions for polysubstituted piperidines: application to the synthesis and preliminary biological screening of a prototype library

Phase-switch synthesis with boronic acids as productive tags

Practical and efficient multigram preparation of a camphor-derived diol for the enantioselective Lewis acid catalyzed allylboration of aldehydes

Rationally improved chiral Brønsted acid for catalytic enantioselective allylboration of aldehydes with an expanded reagent scope.

Reaction Optimization, Scalability, and Mechanistic Insight on the Catalytic Enantioselective Desymmetrization of 1,1-Diborylalkanes via Suzuki-Miyaura Cross-Coupling

Recent advances in the activation of boron and silicon reagents for stereocontrolled allylation reactions

Resin-to-resin suzuki coupling of solid supported arylboronic acids

Ring Structure and Aromatic Substituent Effects on the pK a of the Benzoxaborole Pharmacophore

Scandium-catalyzed allylboration of aldehydes as a practical method for highly diastereo- and enantioselective construction of homoallylic alcohols

Scope and Mechanism of a True Organocatalytic Beckmann Rearrangement with a Boronic Acid/Perfluoropinacol System under Ambient Conditions

Screening of a combinatorial library of synthetic polyamines displaying selectivity in multiple ion-pairing interactions with model polyanionic compounds in aqueous organic solutions

Simple, Stable, and Versatile Double-Allylation Reagents for the Stereoselective Preparation of Skeletally Diverse Compounds

Solid phase syntheses of polyamine toxins HO-416b and PhTX-433. Use of an efficient polyamide reduction strategy that facilitates access to branched analogues

Solid-phase synthesis of cleavable N-arylmaleimides: applications in 1,3-dipolar cycloaddition and in thiol scavenging

Solution- and solid-phase strategies for the design, synthesis, and screening of libraries based on natural product templates: a comprehensive survey.

Spatiotemporal Control of Synergistic Gel Disintegration Consisting of Boroxole- and Glyco-Based Polymers via Photoinduced Proton Transfer

Stereoselective and Regiodivergent Allylic Suzuki-Miyaura Cross-Coupling of 2-Ethoxydihydropyranyl Boronates: Synthesis and Confirmation of Absolute Stereochemistry of Diospongin B

Stereoselective preparation of β-aryl-β-boronyl enoates and their copper-catalyzed enantioselective conjugate reduction

Synergic "Click" Boronate/Thiosemicarbazone System for Fast and Irreversible Bioorthogonal Conjugation in Live Cells.

Synthesis and high performance liquid chromatography/electrospray mass spectrometry single-bead decoding of split-pool structural libraries of polyamines supported on polystyrene and polystyrene/ethylene glycol resins.

Synthesis and preliminary antibacterial evaluation of simplified thiomarinol analogs

Synthesis of chiral heterocycles by ligand-controlled regiodivergent and enantiospecific Suzuki Miyaura cross-coupling.

Synthesis of the non-peptidic snail toxin 6-bromo-2-mercaptotryptamine dimer (BrMT)(2), its lower and higher thio homologs and their ability to modulate potassium ion channels

Tandem Aza

Three-component sequential aza[4+2] cycloaddition/allylboration/retro-sulfinyl-ene reaction: a new stereocontrolled entry to palustrine alkaloids and other 2,6-disubstituted piperidines