Search filters

List of works by George K Christophides

A comprehensive analysis of malaria transmission in Brazil

article

A large-scale stochastic spatiotemporal model for Aedes albopictus-borne chikungunya epidemiology

scientific article

A novel genetic screen for snRNP assembly factors in yeast identifies a conserved protein, Sad1p, also required for pre-mRNA splicing

scientific article

A serine protease homolog negatively regulates TEP1 consumption in systemic infections of the malaria vector Anopheles gambiae

scientific article published on 8 July 2014

Adaptive divergence between incipient species of Anopheles gambiae increases resistance to Plasmodium

scientific article

Advancing insect vector biology research: a community survey for future directions, research applications and infrastructure requirements

Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements

scientific article published on June 2016

An epigenetic map of malaria parasite development from host to vector

scientific article published on 14 April 2020

An expression map for Anopheles gambiae

scientific article published on December 20, 2011

AnoEST: toward A. gambiae functional genomics

scientific article

Anopheles and Plasmodium: from laboratory models to natural systems in the field

scientific article published on 10 November 2006

Anopheles gambiae PGRPLC-mediated defense against bacteria modulates infections with malaria parasites

scientific article

Anopheles gambiae antiviral immune response to systemic O'nyong-nyong infection

scientific article

Anopheles gambiae blood feeding initiates an anticipatory defense response to Plasmodium berghei.

scientific article

Antibiotic Treatment in Anopheles coluzzii Affects Carbon and Nitrogen Metabolism

scientific article published on 21 August 2020

Antibiotics in ingested human blood affect the mosquito microbiota and capacity to transmit malaria

scientific article

Asaia accelerates larval development of Anopheles gambiae

scientific article published on 26 July 2013

Characterization of Plasmodium developmental transcriptomes in Anopheles gambiae midgut reveals novel regulators of malaria transmission

scientific article (publication date: February 2015)

Climate and human health: the impact of climate change on vector-borne diseases, Paphos, Cyprus (17-19 October 2012)

scientific article published on December 2013

Climate change and vector-borne diseases of humans

scientific article published in April 2015

Climate, environmental and socio-economic change: weighing up the balance in vector-borne disease transmission

scientific article

Comparative and functional genomics of the innate immune system in the malaria vector Anopheles gambiae

scientific article

Comparative genome and proteome analysis of Anopheles gambiae and Drosophila melanogaster

scientific article (publication date: 4 October 2002)

Comparative genomics of insect immunity

scholarly article published 25 June 2009

Comprehensive genetic dissection of the hemocyte immune response in the malaria mosquito Anopheles gambiae.

scientific article

Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa

scientific article

Correction to 'Present and future projections of habitat suitability of the Asian tiger mosquito, a vector of viral pathogens, from global climate simulation'.

scientific article published in September 2015

Detection of viable plasmodium ookinetes in the midguts of anopheles coluzzi using PMA-qrtPCR.

scientific article

Differential Effects of Azithromycin, Doxycycline, and Cotrimoxazole in Ingested Blood on the Vectorial Capacity of Malaria Mosquitoes

scientific article

Discovery and characterization of two Nimrod superfamily members in Anopheles gambiae

scientific article

Effects of mosquito genes on Plasmodium development

scientific article published in March 2004

Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes

scientific article

Expression and function of the Drosophila melanogaster ADH in male Ceratitis capitata adults: a potential strategy for medfly genetic sexing based on gene-transfer technology

scientific article published in June 2001

Flow cytometry analysis of the microbiota associated with the midguts of vector mosquitoes

scientific article

Functional analysis of the three major PGRPLC isoforms in the midgut of the malaria mosquito Anopheles coluzzii

scientific article published on 21 November 2019

Functional genomic analysis of midgut epithelial responses in Anopheles during Plasmodium invasion

scientific article

Gene expression in insecticide resistant and susceptible Anopheles gambiae strains constitutively or after insecticide exposure

scientific article published in October 2005

Genetic dissection of Anopheles gambiae gut epithelial responses to Serratia marcescens

scientific article

Genome expression analysis of Anopheles gambiae: responses to injury, bacterial challenge, and malaria infection

scientific article

Genomic analysis of Drosophila chromosome underreplication reveals a link between replication control and transcriptional territories

scientific article

Hidden variable analysis of transcription factor cooperativity from microarray time courses

scientific article published in March 2010

Identification and Antibioresistance Characterisation of Culturable Bacteria in the Intestinal Microbiota of Mosquitoes

article

Immune resistance and tolerance strategies in malaria vector and non-vector mosquitoes

scientific article

Immune signaling pathways regulating bacterial and malaria parasite infection of the mosquito Anopheles gambiae

scientific article

Immunity-related genes and gene families in Anopheles gambiae

scientific article published in October 2002

Impact of repeated NeemAzal-treated blood meals on the fitness of Anopheles stephensi mosquitoes

scientific article

In vitro and ex vivo activity of an Azadirachta indica A.Juss. seed kernel extract on early sporogonic development of Plasmodium in comparison with azadirachtin A, its most abundant constituent

scientific article published on 28 October 2016

Infection intensity-dependent responses of Anopheles gambiae to the African malaria parasite Plasmodium falciparum

scientific article published on 15 August 2011

Innate immunity in the malaria vector Anopheles gambiae: comparative and functional genomics

scientific article published on July 2004

Integral Gene Drives: an "operating system" for population replacement

article

Integral gene drives for population replacement

article

Large-Scale Modelling of the Environmentally-Driven Population Dynamics of Temperate Aedes albopictus (Skuse)

scientific article

Larval diet affects mosquito development and permissiveness to Plasmodium infection

scientific article published on 02 December 2016

Leucine-rich repeat protein complex activates mosquito complement in defense against Plasmodium parasites.

scientific article published on 05 March 2009

Life cycle transcriptome of the malaria mosquito Anopheles gambiae and comparison with the fruitfly Drosophila melanogaster

scholarly article

Male-Specific Protein Disulphide Isomerase Function is Essential for Plasmodium Transmission and a Vulnerable Target for Intervention.

scientific article published on 04 December 2019

Medfly promoters relevant to the sterile insect technique

scientific article published on February 2004

Meeting report of the Mosquito Kolymbari Meeting 2013.

scientific article published on December 2013

Melanotic pathology and vertical transmission of the gut commensal Elizabethkingia meningoseptica in the major malaria vector Anopheles gambiae.

scientific article

Microbiota-induced peritrophic matrix regulates midgut homeostasis and prevents systemic infection of malaria vector mosquitoes.

scientific article

Mosquito genomics. Highly evolvable malaria vectors: the genomes of 16 Anopheles mosquitoes

scientific article published on 27 November 2014

Novel factors of Anopheles gambiae haemocyte immune response to Plasmodium berghei infection.

scientific article published on 9 February 2016

Organization, evolution and expression of a multigene family encoding putative members of the odourant binding protein family in the medfly Ceratitis capitata

scientific article published in April 2000

PIMMS43 is required for malaria parasite immune evasion and sporogonic development in the mosquito vector

scientific article published on 12 March 2020

Paternal effect of the nuclear formin-like protein MISFIT on Plasmodium development in the mosquito vector

scientific article (publication date: August 2009)

Pathogenomics of Culex quinquefasciatus and meta-analysis of infection responses to diverse pathogens

scientific article

Plasmodium berghei P47 is essential for ookinete protection from the Anopheles gambiae complement-like response

scientific article published on 20 July 2017

Plasmodium berghei PIMMS2 promotes ookinete invasion of the Anopheles gambiae mosquito midgut

scientific article published on 30 May 2017

Plasmodium transmission blocking activities of Vernonia amygdalina extracts and isolated compounds

scientific article published on 25 July 2015

Population biology of malaria within the mosquito: density-dependent processes and potential implications for transmission-blocking interventions

scientific article

Present and future projections of habitat suitability of the Asian tiger mosquito, a vector of viral pathogens, from global climate simulation.

scientific article

Proteomic analysis of the Plasmodium male gamete reveals the key role for glycolysis in flagellar motility.

scientific article

SNP genotyping defines complex gene-flow boundaries among African malaria vector mosquitoes.

scientific article

SUUR joins separate subsets of PcG, HP1 and B-type lamin targets in Drosophila

scientific article published in July 2007

Seasonality and locality affect the diversity of Anopheles gambiae and Anopheles coluzzii midgut microbiota from Ghana

scientific article

Sequence-structure-function relations of the mosquito leucine-rich repeat immune proteins.

scientific article

Stability of the effect of silencing fibronectin type III domain-protein 1 (FN3D1) gene on Anopheles arabiensis reared under different breeding site conditions

scientific article published on 19 April 2020

Stimulation of a protease targeting the LRIM1/APL1C complex reveals specificity in complement-like pathway activation in Anopheles gambiae

scientific article published on 08 April 2019

Streamlined SMFA and mosquito dark-feeding regime significantly improve malaria transmission-blocking assay robustness and sensitivity

article

Structure-function analysis of the Anopheles gambiae LRIM1/APL1C complex and its interaction with complement C3-like protein TEP1

scientific article

Testing non-autonomous antimalarial gene drive effectors using self-eliminating drivers in the African mosquito vector Anopheles gambiae

scientific article published on 02 June 2022

The CLIP-domain serine protease homolog SPCLIP1 regulates complement recruitment to microbial surfaces in the malaria mosquito Anopheles gambiae

scientific article published in 2013

The Genome Sequence of the Malaria Mosquito Anopheles gambiae

scientific article

The Peptidoglycan Recognition Proteins PGRPLA and PGRPLB Regulate Anopheles Immunity to Bacteria and Affect Infection by Plasmodium

scientific article published on 12 May 2017

The Plasmodium parasite--a 'new' challenge for insect innate immunity.

scientific article

The effect of silencing immunity related genes on longevity in a naturally occurring Anopheles arabiensis mosquito population from southwest Ethiopia

article

The evolution of the Anopheles 16 genomes project

scientific article published on 08 July 2013

The role of environmental variables on Aedes albopictus biology and chikungunya epidemiology

scientific article

The role of reactive oxygen species on Plasmodium melanotic encapsulation in Anopheles gambiae

scientific article

The serine protease homolog CLIPA14 modulates the intensity of the immune response in the mosquito Anopheles gambiae

scientific article published on 19 September 2017

Toward the Definition of Efficacy and Safety Criteria for Advancing Gene Drive-Modified Mosquitoes to Field Testing

scientific article published on 09 March 2020

Transcription regulation of sex-biased genes during ontogeny in the malaria vector Anopheles gambiae

scientific article

Transcriptional analysis of insecticide resistance in Anopheles stephensi using cross-species microarray hybridization.

scientific article published on 13 April 2007

Transcriptional silencing and activation of paternal DNA during Plasmodium berghei zygotic development and transformation to oocyst

scientific article

Transgenic mosquitoes and malaria transmission

scientific article

Transmission blocking activity of Azadirachta indica and Guiera senegalensis extracts on the sporogonic development of Plasmodium falciparum field isolates in Anopheles coluzzii mosquitoes

scientific article published on 15 April 2014

Transmission blocking immunity in the malaria non-vector mosquito Anopheles quadriannulatus species A

scientific article

VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center

scientific article published on 28 October 2021

Vector and vector-borne disease research: need for coherence, vision and strategic planning

scientific article published on December 2013

VectorBase: a data resource for invertebrate vector genomics

scientific article

VectorBase: a home for invertebrate vectors of human pathogens

scientific article

Widespread divergence between incipient Anopheles gambiae species revealed by whole genome sequences

scientific article

Wind direction and proximity to larval sites determines malaria risk in Kilifi District in Kenya

scientific article published on 14 February 2012