List of works - Karl Matter

An apical MRCK-driven morphogenetic pathway controls epithelial polarity.

scientific article published on 21 August 2017

Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant

scientific article published on 01 September 1991

Basolateral sorting of LDL receptor in MDCK cells: the cytoplasmic domain contains two tyrosine-dependent targeting determinants

scientific article

Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition

scientific article

Biogenesis of tight junctions: The c-terminal domain of occludin mediates basolateral targeting ⬇️

scientific article published on February 1, 1998

Carbohydrate-mediated Golgi to cell surface transport and apical targeting of membrane proteins ⬇️

scientific article published on April 1, 1998

Control of neural crest induction by MarvelD3-mediated attenuation of JNK signalling

scientific article published on 19 January 2018

Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation

scientific article published on 30 December 2013

Dynamics and functions of tight junctions

scientific article published on 12 January 2010

Epithelial cell adhesion and the regulation of gene expression

scientific article

Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex

scientific article

Epithelial polarity: sorting out the sorters.

scientific article

Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility

scientific article published on 13 February 2019

Epithelial tight junctions, gene expression and nucleo-junctional interplay

scientific article published on May 2007

Fc gamma RII-B1 regulates the presentation of B cell receptor-bound antigens ⬇️

scientific article published on September 1, 1998

Functional analysis of tight junctions

scientific article

Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin

scientific article

Holey barrier: claudins and the regulation of brain endothelial permeability

scientific article

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family

scientific article

Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability

scientific article

Lowe Syndrome protein OCRL1 supports maturation of polarized epithelial cells.

scientific article

Mammalian tight junctions in the regulation of epithelial differentiation and proliferation

scientific article

MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival

scientific article

MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus.

scientific article published on 15 November 2016

Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy

scientific article

Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.

scientific article published on December 2009

Occldin and the Functions of Tight Junctions

scientific article published on 01 January 1999

Occludin modulates transepithelial migration of neutrophils.

scientific article

Organization on the plasma membrane of the retinitis pigmentosa protein RP2: investigation of association with detergent-resistant membranes and polarized sorting ⬇️

scientific article published on June 2003

Ouabain modulates epithelial cell tight junction.

scientific article

PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium

scientific article

Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposure

scientific article published in November 2007

RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity

scientific article

Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA

scientific article

Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin

scientific article

Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2

scientific article

Rho signaling and tight junction functions

scientific article published on February 2010

Signalling at tight junctions during epithelial differentiation and microbial pathogenesis

scientific article

Signalling to and from tight junctions

scientific article

SnapShot: Epithelial Tight Junctions

scientific article published on 01 May 2014

Sorting of endogenous plasma membrane proteins occurs from two sites in cultured human intestinal epithelial cells (Caco-2).

scientific article published on February 1990

Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis

scientific article published on 23 January 2011

Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion

scientific article (publication date: 2012)

Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival

scientific article

Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells.

scientific article

TOPORS, implicated in retinal degeneration, is a cilia-centrosomal protein

scientific article

The Cytoplasmic Domains of a β1 Integrin Mediate Polarization in Madin-Darby Canine Kidney Cells by Selective Basolateral Stabilization ⬇️

scientific article published on November 6, 1998

The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration

scientific article

The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription

scientific article

The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density

scientific article

The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB.

scientific article

The polarized expression of Na+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells

scientific article

The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice

scientific article

The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesion

scientific article

Tight junctions and the regulation of gene expression

scientific article published on 11 December 2008

Tight junctions as regulators of tissue remodelling

scientific article published on 26 May 2016

Tight junctions at a glance

scientific article

Tight junctions in health and disease

article

Tight junctions: molecular architecture and function

scientific article

Transepithelial migration of neutrophils.

scientific article

Transmembrane proteins of tight junctions.

scientific article

ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation

scientific article

ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells

scientific article

List of works by Karl Matter

An apical MRCK-driven morphogenetic pathway controls epithelial polarity.

Basolateral sorting in MDCK cells requires a distinct cytoplasmic domain determinant

Basolateral sorting of LDL receptor in MDCK cells: the cytoplasmic domain contains two tyrosine-dependent targeting determinants

Binding of GEF-H1 to the tight junction-associated adaptor cingulin results in inhibition of Rho signaling and G1/S phase transition

Biogenesis of tight junctions: The c-terminal domain of occludin mediates basolateral targeting ⬇️

Carbohydrate-mediated Golgi to cell surface transport and apical targeting of membrane proteins ⬇️

Control of neural crest induction by MarvelD3-mediated attenuation of JNK signalling

Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiation

Dynamics and functions of tight junctions

Epithelial cell adhesion and the regulation of gene expression

Epithelial junction formation requires confinement of Cdc42 activity by a novel SH3BP1 complex

Epithelial polarity: sorting out the sorters.

Epithelial polarization in 3D matrix requires DDR1 signaling to regulate actomyosin contractility

Epithelial tight junctions, gene expression and nucleo-junctional interplay

Fc gamma RII-B1 regulates the presentation of B cell receptor-bound antigens ⬇️

Functional analysis of tight junctions

Functional interaction between the ZO-1-interacting transcription factor ZONAB/DbpA and the RNA processing factor symplekin

Holey barrier: claudins and the regulation of brain endothelial permeability

Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family

Identification of a tight junction-associated guanine nucleotide exchange factor that activates Rho and regulates paracellular permeability

Lowe Syndrome protein OCRL1 supports maturation of polarized epithelial cells.

Mammalian tight junctions in the regulation of epithelial differentiation and proliferation

MarvelD3 couples tight junctions to the MEKK1-JNK pathway to regulate cell behavior and survival

MarvelD3 regulates the c-Jun N-terminal kinase pathway during eye development in Xenopus.

Mutations in TOPORS cause autosomal dominant retinitis pigmentosa with perivascular retinal pigment epithelium atrophy

Myosin IXa regulates epithelial differentiation and its deficiency results in hydrocephalus.

Occldin and the Functions of Tight Junctions

Occludin modulates transepithelial migration of neutrophils.

Organization on the plasma membrane of the retinitis pigmentosa protein RP2: investigation of association with detergent-resistant membranes and polarized sorting ⬇️

Ouabain modulates epithelial cell tight junction.

PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium

Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposure

RalA interacts with ZONAB in a cell density-dependent manner and regulates its transcriptional activity

Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpA

Regulation of renal epithelial tight junctions by the von Hippel-Lindau tumor suppressor gene involves occludin and claudin 1 and is independent of E-cadherin

Regulation of tight junction assembly and epithelial morphogenesis by the heat shock protein Apg-2

Rho signaling and tight junction functions

Signalling at tight junctions during epithelial differentiation and microbial pathogenesis

Signalling to and from tight junctions

SnapShot: Epithelial Tight Junctions

Sorting of endogenous plasma membrane proteins occurs from two sites in cultured human intestinal epithelial cells (Caco-2).

Spatially restricted activation of RhoA signalling at epithelial junctions by p114RhoGEF drives junction formation and morphogenesis

Stimulation of cortical myosin phosphorylation by p114RhoGEF drives cell migration and tumor cell invasion

Stress- and Rho-activated ZO-1-associated nucleic acid binding protein binding to p21 mRNA mediates stabilization, translation, and cell survival

Structural requirements and sequence motifs for polarized sorting and endocytosis of LDL and Fc receptors in MDCK cells.

TOPORS, implicated in retinal degeneration, is a cilia-centrosomal protein

The Cytoplasmic Domains of a β1 Integrin Mediate Polarization in Madin-Darby Canine Kidney Cells by Selective Basolateral Stabilization ⬇️

The RhoA activator GEF-H1/Lfc is a transforming growth factor-beta target gene and effector that regulates alpha-smooth muscle actin expression and cell migration

The Y-box factor ZONAB/DbpA associates with GEF-H1/Lfc and mediates Rho-stimulated transcription

The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell density

The heat-shock protein Apg-2 binds to the tight junction protein ZO-1 and regulates transcriptional activity of ZONAB.

The polarized expression of Na+,K+-ATPase in epithelia depends on the association between beta-subunits located in neighboring cells

The tight junction associated signalling proteins ZO-1 and ZONAB regulate retinal pigment epithelium homeostasis in mice

The tumour suppressor DLC2 ensures mitotic fidelity by coordinating spindle positioning and cell-cell adhesion

Tight junctions and the regulation of gene expression

Tight junctions as regulators of tissue remodelling

Tight junctions at a glance

Tight junctions in health and disease

Tight junctions: molecular architecture and function

Transepithelial migration of neutrophils.

Transmembrane proteins of tight junctions.

ZO-1 controls endothelial adherens junctions, cell-cell tension, angiogenesis, and barrier formation

ZONAB promotes proliferation and represses differentiation of proximal tubule epithelial cells