List of works by Felipe J Chaves

6C.04: INTEGRATED SNP ANALYSIS AND METABOLOMIC PROFILES OF METABOLIC SYNDROME.

scientific article published on June 2015

8-oxo-7,8-dihydro-2'-deoxyguanosine as a marker of DNA oxidative stress in individuals with combined familiar hyperlipidemia

scientific article published in June 2008

A gene-environment interaction analysis of plasma selenium with prevalent and incident diabetes: The Hortega study

scientific article

A new PCSK9 gene promoter variant affects gene expression and causes autosomal dominant hypercholesterolemia.

scientific article

A novel CYBA variant, the -675A/T polymorphism, is associated with essential hypertension

scientific article (publication date: August 2007)

A single point mutation in the low-density lipoprotein receptor switches the degradation of its mature protein from the proteasome to the lysosome.

scientific article published on 21 February 2006

A three-allelic polymorphic system in exon 12 of the LDL receptor gene is highly informative for segregation analysis of familial hypercholesterolemia in the Spanish population

scientific article published on 01 July 1996

Additional information on ApoB R3500Q mutation in Spain

scientific article published on 01 June 2003

Altered glutathione system is associated with the presence of distal symmetric peripheral polyneuropathy in type 2 diabetic subjects.

scientific article

Analysis of Sequence Variations in the LDL Receptor Gene in Spain: General Gene Screening or Search for Specific Alterations?

article

Angiotensin II AT1 receptor gene polymorphism and microalbuminuria in essential hypertension

scientific article published on 01 April 2001

Antioxidant Activities and Oxidative Stress Byproducts in Human Hypertension ⬇️

scientific article published on April 21, 2003

Antioxidant enzyme mRNA expression in conjunctival epithelium of healthy human subjects.

scientific article

Arsenic exposure, diabetes-related genes and diabetes prevalence in a general population from Spain

scientific article published on 21 February 2018

Association between AT C573T polymorphism and cardiovascular risk factors in myocardial infarction

scientific article published on 07 June 2010

Association of C677T polymorphism in MTHFR gene, high homocysteine and low HDL cholesterol plasma values in heterozygous familial hypercholesterolemia

scientific article published in January 2009

Association of a mineralocorticoid receptor gene polymorphism with hypertension in a Spanish population.

scientific article published on 26 March 2009

Association of selected ABC gene family single nucleotide polymorphisms with postprandial lipoproteins: results from the population-based Hortega study

scientific article published on 29 January 2010

Benchmarking different approaches for Norovirus genome assembly in metagenome samples

scientific article published on 24 November 2021

Body weight changes and the A-6G polymorphism of the angiotensinogen gene

article

C-reactive protein and incidence of type 2 diabetes in the Pizarra study.

scientific article published on 20 December 2012

Circulating mononuclear cells nuclear factor-kappa B activity, plasma xanthine oxidase, and low grade inflammatory markers in adult patients with familial hypercholesterolaemia

scientific article published on 11 December 2009

Clinical and biochemical characteristics of familial ligand-defective apo B-100 in a South European population

scientific article published in October 2004

Coexistence of EGFR, KRAS, BRAF, and PIK3CA Mutations and ALK Rearrangement in a Comprehensive Cohort of 326 Consecutive Spanish Nonsquamous NSCLC Patients.

scientific article published on 27 April 2017

Common variants of the liver fatty acid binding protein gene influence the risk of type 2 diabetes and insulin resistance in Spanish population

scientific article

Conjunctival Mucin mRNA Expression in Contact Lens Wear

scientific article published in September 2009

DNA methylation patterns in newborns exposed to tobacco in utero

scientific article

Dietary polyunsaturated fatty acids may increase plasma LDL-cholesterol and plasma cholesterol concentrations in carriers of an ABCG1 gene single nucleotide polymorphism: Study in two Spanish populations

article

Different impacts of cardiovascular risk factors on oxidative stress.

scientific article

Discordant Response of Glutathione and Thioredoxin Systems in Human Hypertension?

scientific article published on 01 April 2007

Do Genes Modify the Association of Selenium and Lipid Levels?

article

ELOVL6 genetic variation is related to insulin sensitivity: a new candidate gene in energy metabolism

scientific article

Effects of marathon running on plasma total homocysteine concentrations

scientific article published on 13 April 2005

Enhanced reduction in oxidative stress and altered glutathione and thioredoxin system response to unsaturated fatty acid load in familial hypercholesterolemia

scientific article published on 15 September 2014

Evaluation of clinical diagnosis criteria of familial ligand defective apoB 100 and lipoprotein phenotype comparison between LDL receptor gene mutations affecting ligand-binding domain and the R3500Q mutation of the apoB gene in patients from a Sout

scientific article

Gene expression profile following an oral unsaturated fat load in abdominal obese subjects.

scientific article published on 8 March 2018

Genetic Variants in CCNB1 Associated With Differential Gene Transcription and Risk of Coronary In-Stent Restenosis

article

Genetic bases of urinary albumin excretion and related traits in hypertension

scientific article published on February 2010

Genetic diagnosis of familial hypercholesterolemia in a South European outbreed population: influence of low-density lipoprotein (LDL) receptor gene mutations on treatment response to simvastatin in total, LDL, and high-density lipoprotein cholester

scientific article

Genomic and Metabolomic Profile Associated to Clustering of Cardio-Metabolic Risk Factors.

scientific article

Genomic and metabolomic profile associated to microalbuminuria.

scientific article

Ghrelin Gene Variants Influence on Metabolic Syndrome Components in Aged Spanish Population.

scientific article published on 16 September 2015

Ghrelin attenuates hepatocellular injury and liver fibrogenesis in rodents and influences fibrosis progression in humans

scientific article published in March 2010

Glucose impairment and ghrelin gene variants are associated to cognitive dysfunction

scientific article published on 12 March 2014

How ineffective hypertension control in subjects treated with angiotensin-converting enzyme inhibitors is related to polymorphisms in the renin-angiotensin-aldosterone system

scientific article published on 20 January 2010

Human and experimental evidence supporting a role for osteopontin in alcoholic hepatitis.

scientific article published on 19 August 2013

Human epithelium from conjunctival impression cytology expresses MUC7 mucin gene.

scientific article

Hypertension and the fat-soluble vitamins A, D and E.

scientific article

Identification of candidate polymorphisms on stress oxidative and DNA damage repair genes related with clinical outcome in breast cancer patients.

scientific article published on 5 December 2012

Identification of novel SLC3A1 gene mutations in Spanish cystinuria families and association with clinical phenotypes

scientific article published in March 2005

Immune-unreactive urinary albumin as a predictor of cardiovascular events: the Hortega Study

scientific article published on 01 April 2019

Impact of cardiovascular risk factors on oxidative stress and DNA damage in a high risk Mediterranean population

scientific article published in December 2009

Impact of obesity-related genes in Spanish population

scientific article

Impact of the components of metabolic syndrome on oxidative stress and enzymatic antioxidant activity in essential hypertension.

scientific article published on 26 October 2006

Importance of HDL cholesterol levels and the total/ HDL cholesterol ratio as a risk factor for coronary heart disease in molecularly defined heterozygous familial hypercholesterolaemia

scientific article

In silico epigenetics of metal exposure and subclinical atherosclerosis in middle aged men: pilot results from the Aragon Workers Health Study.

scientific article published in June 2018

Inadequate Cytoplasmic Antioxidant Enzymes Response Contributes to the Oxidative Stress in Human Hypertension

scientific article published on 01 January 2007

Incidence of diabetes mellitus in Spain as results of the nation-wide cohort di@bet.es study

scientific article published on 17 February 2020

Increased Urinary Exosomal MicroRNAs in Patients with Systemic Lupus Erythematosus.

scientific article published on 21 September 2015

Increased oxidative stress levels and normal antioxidant enzyme activity in circulating mononuclear cells from patients of familial hypercholesterolemia

scientific article published in October 2009

Increased plasma xanthine oxidase activity is related to nuclear factor kappa beta activation and inflammatory markers in familial combined hyperlipidemia

scientific article published on 17 September 2009

Inefficient arterial hypertension control in patients with metabolic syndrome and its link to renin–angiotensin–aldosterone system polymorphisms

scientific article published on 07 April 2011

Influence of FH Valencia 1 and 2 mutations of the LDL receptor gene on the response to simvastatin in subjects with molecularly defined heterozygous familial hypercholesterolemia in Spain

scientific article

Influence of LDL receptor gene mutations and the R3500Q mutation of the apoB gene on lipoprotein phenotype of familial hypercholesterolemic patients from a South European population

scientific article published in December 2003

Influence of microsomal triglyceride transfer protein promoter polymorphism -493 GT on fasting plasma triglyceride values and interaction with treatment response to atorvastatin in subjects with heterozygous familial hypercholesterolaemia

scientific article published in April 2005

Influence of plasma lipids, APOE genotype and type of LDL receptor gene mutations on myocardial infarction in subjects with familial hypercholesterolemia

scientific article published in May 2002

Influence of the I/D polymorphism of the angiotensin-converting enzyme gene on the outcome of microalbuminuria in essential hypertension

scientific article published on 01 January 2000

Iron deficiency is associated with Hypothyroxinemia and Hypotriiodothyroninemia in the Spanish general adult population: Di@bet.es study.

scientific article published on 26 April 2018

LDL particle size and composition and incident cardiovascular disease in a South-European population: The Hortega-Liposcale Follow-up Study

scientific article published on 29 March 2018

Large rearrangements of the LDL receptor gene and lipid profile in a FH Spanish population.

scientific article

Levels of mucin gene expression in normal human conjunctival epithelium in vivo.

scientific article published on November 2003

Metabolically healthy but obese, a matter of time? Findings from the prospective Pizarra study.

scientific article published on 4 April 2013

Metabolomic profiling in blood from umbilical cords of low birth weight newborns

scientific article published on 9 July 2012

Microalbuminuria and oxidative stress in essential hypertension

scientific article published in May 2004

Molecular genetics of familial hypercholesterolemia in Spain: Ten novel LDLR mutations and population analysis

article

Mutational analysis of BRCA1 and BRCA2 genes in Spanish women with early-onset breast cancer

scientific article published on 12 March 2000

Mutational analysis of BRCA1 and BRCA2 in Mediterranean Spanish women with early-onset breast cancer: identification of three novel pathogenic mutations

scientific article published in November 2003

Normal human conjunctival epithelium expresses MUC13, MUC15, MUC16 and MUC17 mucin genes

scientific article published in July 2003

Ocular mucin gene expression levels as biomarkers for the diagnosis of dry eye syndrome.

scientific article published on 28 October 2011

One-year follow-up of clinical, metabolic and oxidative stress profile of morbid obese patients after laparoscopic sleeve gastrectomy. 8-oxo-dG as a clinical marker.

scientific article published on 14 February 2017

Oxidative stress and antioxidant enzyme values in lymphomonocytes after an oral unsaturated fat load test in familial hypercholesterolemic subjects

scientific article published on 13 October 2012

Oxidative stress in susceptibility to breast cancer: study in Spanish population

scientific article

Plasma Lp(a) values in familial hypercholesterolemia and its relation to coronary heart disease

scientific article published on 01 February 1999

Plasma homocysteine levels are associated with ulceration of the foot in patients with type 2 diabetes mellitus

scientific article published in February 2010

Plasma homocysteine levels are independently associated with the severity of peripheral polyneuropathy in type 2 diabetic subjects

scientific article published on 01 June 2012

Plasma selenium levels and oxidative stress biomarkers: A gene–environment interaction population-based study

article

Polymorphism insertion/deletion of the ACE gene and ambulatory blood pressure circadian variability in essential hypertension

scientific article published on 01 February 2001

Polymorphisms in endothelin system genes, arsenic levels and obesity risk.

scientific article

Polymorphisms in the SCD1 gene are associated with indices of stearoyl CoA desaturase activity and obesity: a prospective study.

scientific article

Polymorphisms of antioxidant enzymes, blood pressure and risk of hypertension

scientific article published on 01 March 2011

Polymorphisms of the UCP2 gene are associated with body fat distribution and risk of abdominal obesity in Spanish population.

scientific article published on 23 August 2011

Polymorphisms of the angiotensinogen gene and the outcome of microalbuminuria in essential hypertension: a 3-year follow-up study

scientific article published in January 2004

Polymorphisms of the renin-angiotensin system influence height in normotensive women in a Spanish population

scientific article published in May 2004

Population-Based National Prevalence of Thyroid Dysfunction in Spain and Associated Factors: Di@bet.es Study

scientific article published on 11 November 2016

Postprandial Changes in Chemokines Related to Early Atherosclerotic Processes in Familial Hypercholesterolemic Subjects: A Preliminary Study

scientific article published on 25 January 2016

Reduced penetrance of autosomal dominant hypercholesterolemia in a high percentage of families: importance of genetic testing in the entire family

scientific article published on 30 July 2011

Renin polymorphisms and haplotypes are associated with blood pressure levels and hypertension risk in postmenopausal women

scientific article

Renin-angiotensin system gene polymorphisms: relationship with blood pressure and microalbuminuria in telmisartan-treated hypertensive patients

scientific article published in January 2005

Risk factors associated with retinal vein occlusion

scientific article published on 18 February 2014

Semiquantitative multiplex PCR: a useful tool for large rearrangement screening and characterization.

scientific article

Serum sCD163 levels are associated with type 2 diabetes mellitus and are influenced by coffee and wine consumption: results of the Di@bet.es study

scientific article

Seven DNA polymorphisms in the LDL receptor gene: application to the study of familial hypercholesterolemia in Spain

scientific article published on 01 July 1996

The gut mycobiome composition is linked to carotid atherosclerosis.

scientific article

The nutrigenetic influence of the interaction between dietary vitamin E and TXN and COMT gene polymorphisms on waist circumference: a case control study

scientific article

The relation between obesity, abdominal fat deposit and the angiotensin-converting enzyme gene I/D polymorphism and its association with coronary heart disease.

scientific article published in January 2005

Urinary 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxo-dG), a reliable oxidative stress marker in hypertension

scientific article published on 01 May 2007

Urinary dedifferentiated podocytes as a non-invasive biomarker of lupus nephritis

Urinary levels of sirtuin-1 associated with disease activity in lupus nephritis

scientific article published on 12 February 2018

VISMapper: ultra-fast exhaustive cartography of viral insertion sites for gene therapy.

scientific article published on 20 September 2017

Xanthine oxidoreductase polymorphisms: influence in blood pressure and oxidative stress levels

scientific article published on 01 August 2007

[Correlation between plasma concentrations of homocysteine and diabetic polyneuropathy evaluated with the Semmes-Weinstein monofilament test in patients with type 2 diabetes mellitus]

scientific article published on 18 January 2013

[Determinants of postprandial lipemia measured as diurnal triglyceride profile in non diabetic normolipidemic subjects].

scientific article published in October 2005

[Effect of gender and obesity on postprandial lipemia in non-diabetic normolipidemic subjects and subjects with familial combined hyperlipidemia]

scientific article published on 01 May 2006

[Familial defect of apo B-100 in subjects with clinically diagnosed primary hypercholesterolemia: identification of the first family with this disorder in Spain]

scientific article published on 01 June 1999

[Familial hypercholesterolemia and plasma Lp(a) levels: 2 cardiovascular risk factors]

scientific article published on 01 February 1999

[Familial hypercholesterolemia: molecular identification and characterization of the first compound homozygote in Spain]

scientific article published on 01 March 1998

[Genetic polymorphisms of the renin-angiotensin system and essential hypertension]

scientific article published on 01 April 2002

[Insertion/deletion polymorphism of the gene encoding for angiotensin-converting enzyme and microalbuminuria in essential arterial hypertension]

scientific article published on 01 May 1999

[Plasma IL-18 levels are related to insulin and are modulated by IL-18 gene polymorphisms]

scientific article published on 20 July 2015

[Plasma lipoprotein (a) values in familial defective ligand apo B 100 in a South European population]

scientific article published on 01 July 2004

[Remediable glucocorticoid hyperaldosteronism: molecular diagnosis]

scientific article published on 01 November 1999

[Renin-angiotensin system genetic polymorphisms and essential hypertension in the Spanish population]

scientific article published on 01 November 2001

mRNA expression profiles obtained from microdissected pancreatic cancer cells can predict patient survival

scientific article published on 3 August 2017

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