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List of works by Refaat B. Hamed

A natural solution to photoprotection and isolation of the potent polyene antibiotic, marinomycin A

scientific article published on 21 May 2019

Biocatalytic production of bicyclic β-lactams with three contiguous chiral centres using engineered crotonases

scientific article published on 24 January 2019

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.

scientific article published on 12 January 2010

Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

article

Crotonases: Nature’s Exceedingly Convertible Catalysts

Evidence for the slow reaction of hypoxia-inducible factor prolyl hydroxylase 2 with oxygen

scientific article

Evidence that thienamycin biosynthesis proceeds via C-5 epimerization: ThnE catalyzes the formation of (2S,5S)-trans-carboxymethylproline.

scientific article published in January 2009

Factor-inhibiting hypoxia-inducible factor (FIH) catalyses the post-translational hydroxylation of histidinyl residues within ankyrin repeat domains

scientific article

Iron-mediated cleavage of C-C bonds in vicinal tricarbonyl compounds in water

scientific article published in January 2009

Living GenoChemetics by hyphenating synthetic biology and synthetic chemistry in vivo

scientific article

Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde

scientific article published in March 2010

Oxygenase-catalyzed ribosome hydroxylation occurs in prokaryotes and humans

scientific article

Photoactivable peptides for identifying enzyme–substrate and protein–protein interactions

scientific article published on 13 December 2010

Self-hydroxylation of the splicing factor lysyl hydroxylase, JMJD6

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases

scientific article published on 3 April 2011

Stereoselective Production of Dimethyl-Substituted Carbapenams via Engineered Carbapenem Biosynthesis Enzymes

Stereoselective preparation of lipidated carboxymethyl-proline/pipecolic acid derivatives via coupling of engineered crotonases with an alkylmalonyl-CoA synthetase

scientific article published on 9 October 2013

Studies on the selectivity of proline hydroxylases reveal new substrates including bicycles

scientific article published on 28 October 2019

Synthesis of regio- and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis.

scientific article

The 2-Oxoglutarate-Dependent Oxygenase JMJD6 Catalyses Oxidation of Lysine Residues to give 5S-Hydroxylysine Residues

scientific article published on 18 January 2011

The enzymes of β-lactam biosynthesis

scientific article

Thioester Hydrolysis and CC Bond Formation by Carboxymethylproline Synthase from the Crotonase Superfamily

scientific article published on 01 January 2008

Use of Methylmalonyl-CoA Epimerase in Enhancing Crotonase Stereoselectivity.

scientific article