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List of works by Christian Ducho

A biomimetic domino reaction for the concise synthesis of capreomycidine and epicapreomycidine

scientific article published on 23 May 2012

Amalgamation of nucleosides and amino acids in antibiotic biosynthesis: discovery of an L-threonine:uridine-5'-aldehyde transaldolase.

scientific article

Amino acid motifs in natural products: synthesis of O-acylated derivatives of (2S,3S)-3-hydroxyleucine

scientific article

Aminoribosylated Analogues of Muraymycin Nucleoside Antibiotics

Analogues of Muraymycin Nucleoside Antibiotics with Epimeric Uridine-Derived Core Structures

scientific article published on 03 November 2018

Antibacterial Muraymycins from Mutant Strains of Streptomyces sp. NRRL 30471. ⬇️

scientific article published on 19 March 2018

Aryl-substituted and benzo-annulated cyc/osal-derivatives of 2',3'-dideoxy-2',3'-didehydrothymidine monophosphate--correlation of structure, hydrolysis properties and anti-HIV activity

scientific article published in March 2002

Benzyl-functionalized cycloSal-d4T monophosphates

scientific article published in April 2001

Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles.

scientific article published on 12 January 2010

Cellular Targeting of Oligonucleotides by Conjugation with Small Molecules

scientific article published on 16 December 2020

Convergence leads to success: total synthesis of the complex nonribosomal peptide polytheonamide B

scientific article published on 01 July 2010

Crotonase Catalysis Enables Flexible Production of Functionalized Prolines and Carbapenams

article

Enhanced Stability of DNA Oligonucleotides with Partially Zwitterionic Backbone Structures in Biological Media

article published in 2018

Enzymatic Synthesis of the Ribosylated Glycyl-Uridine Disaccharide Core of Peptidyl Nucleoside Antibiotics

scientific article published on 24 May 2018

Enzymatically Cleavable siRNA Prodrugs: a New Paradigm for the Intracellular Delivery of RNA-Based Therapeutics

scientific article published on 12 August 2015

Insights into the Target Interaction of Naturally Occurring Muraymycin Nucleoside Antibiotics

scientific article published on 13 February 2018

Interaction of cycloSal-pronucleotides with cholinesterases from different origins. A structure-activity relationship

scientific article

Lead structures for new antibacterials: stereocontrolled synthesis of a bioactive muraymycin analogue.

scientific article published on 15 October 2014

Mechanism of action of the uridyl peptide antibiotics: an unexpected link to a protein-protein interaction site in translocase MraY.

scientific article

Muraymycin Nucleoside Antibiotics: Structure-Activity Relationship for Variations in the Nucleoside Unit

scientific article published on 19 December 2019

NAA-modified DNA oligonucleotides with zwitterionic backbones: stereoselective synthesis of A-T phosphoramidite building blocks

scientific article

Natural Products at Work: Structural Insights into Inhibition of the Bacterial Membrane Protein MraY.

scientific article published on 11 August 2016

Non-inhibition of acetylcholinesterase by cycloSal nucleotides

scientific article published in May 2003

Novel 5'-deoxy nucleosyl amino acid scaffolds for the synthesis of muraymycin analogues

scientific article published on 01 May 2010

Novel cyclosal nucleotides with reduced inhibitory potency toward human butyrylcholinesterase

scientific article published on 01 January 2005

Oligonucleotide analogues with cationic backbone linkages.

scientific article

Oligonucleotides with Cationic Backbone and Their Hybridization with DNA: Interplay of Base Pairing and Electrostatic Attraction

scientific article published on 19 October 2017

Pyridoxal-5'-phosphate-dependent alkyl transfer in nucleoside antibiotic biosynthesis

scientific article published on 01 June 2020

Specific, Sensitive, and Quantitative Detection of HER-2 mRNA Breast Cancer Marker by Fluorescent Light-Up Hybridization Probes

scientific article published on 31 March 2020

Stereoselective C-C bond formation catalysed by engineered carboxymethylproline synthases

scientific article published on 3 April 2011

Stereoselective Synthesis of Uridine-Derived Nucleosyl Amino Acids

scientific article published on 21 November 2011

Structure-based gene targeting discovery of sphaerimicin, a bacterial translocase I inhibitor

scientific article

Synthesis and properties of DNA oligonucleotides with a zwitterionic backbone structure

scientific article published on 01 November 2014

Synthesis of regio- and stereoselectively deuterium-labelled derivatives of L-glutamate semialdehyde for studies on carbapenem biosynthesis.

scientific article

The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.

scientific article published on 8 April 2015

The bacterial cell envelope as delimiter of anti-infective bioavailability - An in vitro permeation model of the Gram-negative bacterial inner membrane.

scientific article published on 18 October 2016

The enzymes of β-lactam biosynthesis

scientific article

Thioester Hydrolysis and CC Bond Formation by Carboxymethylproline Synthase from the Crotonase Superfamily

scientific article published on 01 January 2008

Total Synthesis of Dansylated Park's Nucleotide for High-Throughput MraY Assays.

scientific article

cycloSal-d4TMP pronucleotides structural variations, mechanistic insights and antiviral activity.

scientific article

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