List of works - Leonela Amoasii

A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism

scientific article published on February 2016

CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells

scientific article published on 06 March 2019

Control of Muscle Metabolism by the Mediator Complex

scientific article published on 21 April 2017

Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy

scientific article published in Science

Genome Editing of Monogenic Neuromuscular Diseases: A Systematic Review

scientific article published on 26 September 2016

In vivo non-invasive monitoring of dystrophin correction in a new Duchenne muscular dystrophy reporter mouse

scientific article published on 04 October 2019

Increased expression of wild-type or a centronuclear myopathy mutant of dynamin 2 in skeletal muscle of adult mice leads to structural defects and muscle weakness

scientific article

Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways

scientific journal article

Loss of catalytically inactive lipid phosphatase myotubularin-related protein 12 impairs myotubularin stability and promotes centronuclear myopathy in zebrafish

scientific article (publication date: June 2013)

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

scientific article published on 24 August 2016

Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo

scientific article published on 26 February 2013

Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle

scientific article

Myotubularin phosphoinositide phosphatases in human diseases

scientific article published on January 2012

NURR1 activation in skeletal muscle controls systemic energy homeostasis

scientific article published on 20 May 2019

Phosphatase-dead myotubularin ameliorates X-linked centronuclear myopathy phenotypes in mice

scientific article

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

scientific article published on 31 December 2015

Primary T-tubule and autophagy defects in the phosphoinositide phosphatase Jumpy/MTMR14 knockout mice muscle

scientific article published on 01 January 2012

Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit

scientific article

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy.

scientific article published in November 2017

List of works by Leonela Amoasii

A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism

CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells

Control of Muscle Metabolism by the Mediator Complex

Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy

Genome Editing of Monogenic Neuromuscular Diseases: A Systematic Review

In vivo non-invasive monitoring of dystrophin correction in a new Duchenne muscular dystrophy reporter mouse

Increased expression of wild-type or a centronuclear myopathy mutant of dynamin 2 in skeletal muscle of adult mice leads to structural defects and muscle weakness

Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways

Loss of catalytically inactive lipid phosphatase myotubularin-related protein 12 impairs myotubularin stability and promotes centronuclear myopathy in zebrafish

MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis

Myotubularin and PtdIns3P remodel the sarcoplasmic reticulum in muscle in vivo

Myotubularin controls desmin intermediate filament architecture and mitochondrial dynamics in human and mouse skeletal muscle

Myotubularin phosphoinositide phosphatases in human diseases

NURR1 activation in skeletal muscle controls systemic energy homeostasis

Phosphatase-dead myotubularin ameliorates X-linked centronuclear myopathy phenotypes in mice

Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

Primary T-tubule and autophagy defects in the phosphoinositide phosphatase Jumpy/MTMR14 knockout mice muscle

Receptor activator of NF-kappaB (RANK) stimulates the proliferation of epithelial cells of the epidermo-pilosebaceous unit

Single-cut genome editing restores dystrophin expression in a new mouse model of muscular dystrophy.