List of works by Helena Carmo

A Metabolomic Approach for the In Vivo Study of Gold Nanospheres and Nanostars after a Single-Dose Intravenous Administration to Wistar Rats

scientific article published on 12 November 2019

A multiparametric study of gold nanoparticles cytotoxicity, internalization and permeability using an in vitro model of blood-brain barrier. Influence of size, shape and capping agent

scientific article published on 08 June 2019

An insight into the hepatocellular death induced by amphetamines, individually and in combination: the involvement of necrosis and apoptosis

scientific article published on 3 July 2013

Benzo fury: A new trend in the drug misuse scene

scientific article published on 05 February 2019

Biodistribution and metabolic profile of 3,4-dimethylmethcathinone (3,4-DMMC) in Wistar rats through gas chromatography-mass spectrometry (GC-MS) analysis

scientific article published on 18 October 2019

CARDIOTOXICITY STUDIES USING FRESHLY ISOLATED CALCIUM-TOLERANT CARDIOMYOCYTES FROM ADULT RAT

scientific article published on 01 January 2001

CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA)

scientific article

Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP.

scientific article published on 8 April 2017

Combination effects of amphetamines under hyperthermia - the role played by oxidative stress.

scientific article published on 13 June 2013

Comparative metabolism of the designer drug 4-methylthioamphetamine by hepatocytes from man, monkey, dog, rabbit, rat and mouse.

scientific article published on 16 December 2003

Copper enhances isoproterenol toxicity in isolated rat cardiomyocytes: effects on oxidative stress

scientific article

Cu2+-induced isoproterenol oxidation into isoprenochrome in adult rat calcium-tolerant cardiomyocytes

scientific article published in June 2002

Development and validation of a GC/IT-MS method for simultaneous quantitation of para and meta-synephrine in biological samples

scientific article published on 23 February 2010

Diet aid or aid to die: an update on 2,4-dinitrophenol (2,4-DNP) use as a weight-loss product

scientific article published on 20 February 2020

Effect of surface coating on the biodistribution profile of gold nanoparticles in the rat.

scientific article published on 16 September 2011

Efficacy, Stability, and Safety Evaluation of New Polyphenolic Xanthones Towards Identification of Bioactive Compounds to Fight Skin Photoaging

scientific article published on 16 June 2020

Emerging club drugs: 5-(2-aminopropyl)benzofuran (5-APB) is more toxic than its isomer 6-(2-aminopropyl)benzofuran (6-APB) in hepatocyte cellular models

scientific article published on 14 December 2019

Ethanol addictively enhances the in vitro cardiotoxicity of cocaine through oxidative damage, energetic deregulation, and apoptosis

scientific article published on 30 May 2018

Ethanol, the forgotten artifact in cell culture

scientific article published on 6 February 2008

Evaluation of GSH adducts of adrenaline in biological samples

scientific article

GC determination of acetone, acetaldehyde, ethanol, and methanol in biological matrices and cell culture.

scientific article published in April 2009

Gas chromatography-ion trap mass spectrometry method for the simultaneous measurement of MDMA (ecstasy) and its metabolites, MDA, HMA, and HMMA in plasma and urine

scientific article published on 4 February 2010

Hepatotoxicity of piperazine designer drugs: Comparison of different in vitro models

scientific article

Hepatotoxicity of piperazine designer drugs: up-regulation of key enzymes of cholesterol and lipid biosynthesis

scientific article published on 28 January 2016

Hepcidin messenger RNA expression in human lymphocytes

scientific article

Hydrogen peroxide production in mouse tissues after acute d-amphetamine administration. Influence of monoamine oxidase inhibition.

scientific article published in October 2001

Identification of 4-methylthioamphetamine and some of its metabolites in mouse urine by GC-MS after acute administration.

scientific article

Impact of in Vitro Gastrointestinal Digestion and Transepithelial Transport on Antioxidant and ACE-Inhibitory Activities of Brewer's Spent Yeast Autolysate

scientific article

Implementation of an in vitro methodology for phototoxicity evaluation in a human keratinocyte cell line

scientific article published on 02 August 2019

In vitro hepatotoxicity of 'Legal X': the combination of 1-benzylpiperazine (BZP) and 1-(m-trifluoromethylphenyl)piperazine (TFMPP) triggers oxidative stress, mitochondrial impairment and apoptosis.

scientific article published on 29 June 2016

In vitro neurotoxicity evaluation of piperazine designer drugs in differentiated human neuroblastoma SH-SY5Y cells

scientific article

In vitro study of P-glycoprotein induction as an antidotal pathway to prevent cytotoxicity in Caco-2 cells ⬇️

scientific article published on September 21, 2010

Induction and activation of P-glycoprotein by dihydroxylated xanthones protect against the cytotoxicity of the P-glycoprotein substrate paraquat

scientific article published on 25 January 2014

Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity

scientific article published on November 2006

Influence of the surface coating on the cytotoxicity, genotoxicity and uptake of gold nanoparticles in human HepG2 cells.

scientific article published on 25 March 2013

Insights on the relationship between structure vs. toxicological activity of antibacterial rhodamine-labelled 3-hydroxy-4-pyridinone iron(III) chelators in HepG2 cells

scientific article published on 01 October 2018

Mercury fatal intoxication: Two case reports

scientific article published on 12 December 2008

Metabolic interactions between ethanol and MDMA in primary cultured rat hepatocytes.

scientific article published on 17 February 2010

Metabolism of the designer drug 4-bromo-2,5-dimethoxyphenethylamine (2C-B) in mice, after acute administration

scientific article published in November 2004

Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations

scientific article

Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy.

scientific article

Molecular and cellular mechanisms of ecstasy-induced neurotoxicity: an overview.

scientific article

Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis

scientific article published on 05 June 2020

Newly Synthesized Oxygenated Xanthones as Potential P-Glycoprotein Activators: , , and Studies

scientific article published on 15 February 2019

P-glycoprotein induction in Caco-2 cells by newly synthetized thioxanthones prevents paraquat cytotoxicity.

scientific article

Piperazine compounds as drugs of abuse.

scientific article

Piperazine designer drugs elicit toxicity in the alternative in vivo model Caenorhabditis elegans

scientific article published on 22 November 2019

Piperazine designer drugs induce toxicity in cardiomyoblast h9c2 cells through mitochondrial impairment.

scientific article

Protective ability against oxidative stress of brewers' spent grain protein hydrolysates.

scientific article published on 12 February 2017

Quantification of Methadone and Main Metabolites in Nails.

scientific article published on 13 December 2017

Quantification of doping compounds in faecal samples from racing pigeons, by liquid chromatography-tandem mass spectrometry

scientific article published on 04 May 2018

Several transport systems contribute to the intestinal uptake of Paraquat, modulating its cytotoxic effects.

scientific article

Short- and long-term distribution and toxicity of gold nanoparticles in the rat after a single-dose intravenous administration

scientific article published on 15 June 2014

Simultaneous determination of amphetamine derivatives in human urine after SPE extraction and HPLC-UV analysis.

scientific article

Study of the intestinal uptake and permeability of gold nanoparticles using both in vitro and in vivo approaches

scientific article published on 21 January 2020

Synergistic toxicity of ethanol and MDMA towards primary cultured rat hepatocytes

scientific article

Synthetic Cannabinoids JWH-122 and THJ-2201 Disrupt Endocannabinoid-Regulated Mitochondrial Function and Activate Apoptotic Pathways as a Primary Mechanism of In Vitro Nephrotoxicity at In Vivo Relevant Concentrations

scientific article published on 01 June 2019

Synthetic cannabinoids and their impact on neurodevelopmental processes

scientific article published on 23 August 2019

The Synthetic Cannabinoids THJ-2201 and 5F-PB22 Enhance In Vitro CB1 Receptor-Mediated Neuronal Differentiation at Biologically Relevant Concentrations

scientific article published on 30 August 2020

The Use of Feathers from Racing Pigeons for Doping Control Purposes

scientific article published on 01 May 2019

The new psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone) induces oxidative stress, apoptosis, and autophagy in primary rat hepatocytes at human-relevant concentrations

scientific article published on 29 August 2019

The novel psychoactive substance 3-methylmethcathinone (3-MMC or metaphedrone): A review

scientific article published on 03 December 2018

The risky cocktail: what combination effects can we expect between ecstasy and other amphetamines?

scientific article

The synthetic cannabinoid XLR-11 induces in vitro nephrotoxicity by impairment of endocannabinoid-mediated regulation of mitochondrial function homeostasis and triggering of apoptosis

scientific article published on 3 February 2018

Toxicity of amphetamines: an update

scientific article

Toxicogenomics directory of chemically exposed human hepatocytes

scientific article

Toxicological Evaluation of Luminescent Silica Nanoparticles as New Drug Nanocarriers in Different Cancer Cell Lines

scientific article published on 28 July 2018

Water extracts of Brassica oleracea var. costata potentiate paraquat toxicity to rat hepatocytes in vitro.

scientific article published on 30 May 2009

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