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List of works by Stela Rates

Acute and repeated-doses (28 days) toxicity study of Hypericum polyanthemum Klotzsch ex Reichardt (Guttiferare) in mice

article

Acylphloroglucinol Derivatives from Hypericum andinum: Antidepressant-like Activity of Andinin A

scientific article published on 29 September 2014

Acylphloroglucinols from Elaphoglossum crassipes: antidepressant-like activity of crassipin A.

scientific article published on 11 June 2012

Antifungal activity of some Brazilian Hypericum species

scientific article published in March 2005

Biotransformation of LASSBio-579 and pharmacological evaluation of p -hydroxylated metabolite a N -phenylpiperazine antipsychotic lead compound

scientific article published on 20 August 2012

Comparisons between anxiety tests for selection of anxious and non anxious mice

scientific article published on 21 February 2006

Design of new dopamine D2 receptor ligands: biosynthesis and pharmacological evaluation of the hydroxylated metabolite of LASSBio-581.

scientific article published on 10 March 2010

Design, synthesis and pharmacological profile of novel dopamine D2 receptor ligands

scientific article published in November 2003

Determination of pharmacological interactions of uliginosin B, a natural phloroglucinol derivative, with amitriptyline, clonidine and morphine by isobolographic analysis

scientific article

Development and validation of a LC-MS/MS method with electrospray ionization for determination of LASSBio-579 in rat plasma

scientific article published on 18 September 2006

Diene Valepotriates from Valeriana glechomifolia Prevent Lipopolysaccharide-Induced Sickness and Depressive-Like Behavior in Mice

scientific article published on 11 June 2015

Dimeric acylphloroglucinols from Hypericum austrobrasiliense exhibiting antinociceptive activity in mice

scientific article published on 23 December 2015

Double continuous injection preparation method of cyclodextrin inclusion compounds by spray drying

Effect of Storage Time and Conditions on the Diene Valepotriates Content of the Extract of Valeriana glechomifolia Obtained by Supercritical Carbon Dioxide

scientific article published on 23 September 2011

Effects of acute or 3-day treatments of Hypericum caprifoliatum Cham. & Schltdt. (Guttiferae) extract or of two established antidepressants on basal and stress-induced increase in serum and brain corticosterone levels

scientific article

Effects of diene valepotriates from Valeriana glechomifolia on Na+/K+-ATPase activity in the cortex and hippocampus of mice.

scientific article published on 23 January 2015

Immobility behavior during the forced swim test correlates with BNDF levels in the frontal cortex, but not with cognitive impairments

scientific article published on 10 December 2014

In vitro effect of valepotriates isolated from Valeriana glechomifolia on rat P-type ATPases

scientific article

In vivo evaluation of the highly soluble oral β-cyclodextrin-Sertraline supramolecular complexes.

scientific article published on 6 July 2012

Inhibition of cytochrome P450-dependent monooxygenases by an alkaloid fraction from Helietta apiculata markedly potentiate the hypnotic action of pentobarbital

scientific article published in March 1998

LASSBio-1422: a new molecular scaffold with efficacy in animal models of schizophrenia and disorders of attention and cognition

scientific article published on 13 October 2016

LASSBio-579, a prototype antipsychotic drug, and clozapine are effective in novel object recognition task, a recognition memory model

scientific article

Monoamine oxidase inhibitory activity of some Hypericum species native to South Brazil ⬇️

scientific article

Mucoadhesive Amphiphilic Methacrylic Copolymer-Functionalized Poly(ε-caprolactone) Nanocapsules for Nose-to-Brain Delivery of Olanzapine

scientific article published on August 2015

Nanoencapsulation Improves Relative Bioavailability and Antipsychotic Effect of Olanzapine in Rats

scientific article published in August 2015

New insights into pharmacological profile of LASSBio-579, a multi-target N-phenylpiperazine derivative active on animal models of schizophrenia

scientific article published on 19 September 2012

Pharmacokinetic evaluation of LASSBio-579: an N-phenylpiperazine antipsychotic prototype

scientific article published in June 2008

Pharmacokinetics and tissue distribution of a new heterocyclic N-phenylpiperazine derivative (LASSBio-581) in rats

scientific article published in October 2005

Plants popularly used for loosing weight purposes in Porto Alegre, South Brazil

scientific article

Psychopharmacological screening of Pfaffia glomerata Spreng. (Amarathanceae) in rodents.

scientific article published in November 2000

Pyridinic analog of the natural product (-)-spectaline as potential adjuvant for the treatment of central nervous system disorders

scientific article published on 9 March 2015

Repeated forced swimming impairs prepulse inhibition and alters brain-derived neurotrophic factor and astroglial parameters in rats

scientific article published on 20 November 2014

Searching for multi-target antipsychotics: Discovery of orally active heterocyclic N-phenylpiperazine ligands of D2-like and 5-HT1A receptors.

scientific article

Serotonergic neurotransmission mediates hypothermia induced by the N-phenylpiperazine antipsychotic prototypes LASSBio-579 and LASSBio-581.

scientific article

Study of antidepressant-like activity of an enriched phloroglucinol fraction obtained from Hypericum caprifoliatum

scientific article published on 9 October 2013

Survey of plants popularly used for pain relief in Rio Grande do Sul, southern Brazil

article

Synergistic interaction between diene valepotriates from Valeriana glechomifolia Meyer (Valerianaceae) and classical antidepressants: an isobolographic analysis

scientific article

Synthesis and pharmacological evaluation of new N-phenylpiperazine derivatives designed as homologues of the antipsychotic lead compound LASSBio-579.

scientific article published on 30 May 2013

The anti-immobility effect of hyperoside on the forced swimming test in rats is mediated by the D2-like receptors activation

scientific article

The antinociceptive effect of a benzopyran (HP1) isolated from Hypericum polyanthemum in mice hot-plate test is blocked by naloxone.

scientific article published on 22 March 2010

Toxicity and genotoxicity evaluation of Passiflora alata Curtis (Passifloraceae).

scientific article

Uliginosin B presents antinociceptive effect mediated by dopaminergic and opioid systems in mice

scientific article

Uliginosin B, a Possible New Analgesic Drug, Acts by Modulating the Adenosinergic System

scientific article

Uliginosin B, a natural phloroglucinol derivative with antidepressant-like activity, increases Na+,K+-ATPase activity in mice cerebral cortex

Uliginosin B, a natural phloroglucinol derivative, presents a multimediated antinociceptive effect in mice

scientific article published on 13 August 2014

Uliginosin B, a phloroglucinol derivative from Hypericum polyanthemum: a promising new molecular pattern for the development of antidepressant drugs

scientific article

Validated HPLC method for determination of LASSBio-581, a new heterocyclic N-phenylpiperazine derivative, in rat plasma

scientific article

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