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List of works by Paul Bishop

A novel Ocular Anaesthetic Scoring System, OASS, tool to measure both motor and sensory function following local anaesthesia.

scientific article

A novel peripherin/RDS mutation resulting in a retinal dystrophy with phenotypic variation

scientific article

Adult vitreous structure and postnatal changes

scientific article published on 29 February 2008

Age and Smoking Related Changes in Metal Ion Levels in Human Lens: Implications for Cataract Formation

scientific article published on 21 January 2016

Age-dependent changes in heparan sulfate in human Bruch's membrane: implications for age-related macular degeneration

scientific article published on 29 July 2014

Age-dependent changes in the basal retinovitreous adhesion

scientific article published on May 2003

Age-related changes on the surface of vitreous collagen fibrils

scientific article published in April 2004

Age-related macular degeneration and the role of the complement system.

scientific article published on 21 March 2015

Age-related macular degeneration: the importance of family history as a risk factor

article

An immune dot-blot test for the diagnosis of ocular infection with Chlamydia trachomatis

scientific article published on January 1991

Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI

scientific article published on 07 August 2020

Assessment of Proteins Associated With Complement Activation and Inflammation in Maculae of Human Donors Homozygous Risk at Chromosome 1 CFH-to-F13B.

scientific article published in July 2015

Axial structure of the heterotypic collagen fibrils of vitreous humour and cartilage.

scientific article

Bilateral subfoveal choroidal neovascularization in Turner's syndrome: coincidence or consequence?

scientific article published on 01 October 1999

Characterisation of the metabolome of ocular tissues and post-mortem changes in the rat retina.

scientific article

Characterization of opticin and evidence of stable dimerization in solution

scientific article

Characterization of opticin digestion by proteases involved in osteoarthritis development

scientific article published on 8 July 2013

Cleavage of structural components of mammalian vitreous by endogenous matrix metalloproteinase-2

scientific article published in April 1996

Cleavage of structural components of mammalian vitreous by endogenous matrix metalloproteinase-2.

scientific article published in April 1996

Collagen fibril organisation in mammalian vitreous by freeze etch/rotary shadowing electron microscopy

scientific article

Complement factor H and age-related macular degeneration: the role of glycosaminoglycan recognition in disease pathology.

scientific article published on October 2010

Complementing the Sugar Code: Role of GAGs and Sialic Acid in Complement Regulation

scientific article

Concentration of various trace elements in the rat retina and their distribution in different structures

article

Crystal structure of the biglycan dimer and evidence that dimerization is essential for folding and stability of class I small leucine-rich repeat proteoglycans

scientific article published on 17 March 2006

Crystal structure of the dimeric protein core of decorin, the archetypal small leucine-rich repeat proteoglycan.

scientific article

Deficient copper concentrations in dried-defatted hepatic tissue from ob/ob mice: A potential model for study of defective copper regulation in metabolic liver disease.

scientific article published on 20 March 2015

Discovery and functional analysis of a retinitis pigmentosa gene, C2ORF71

scientific article

Effects of hyaluronan lyase, hyaluronidase, and chondroitin ABC lyase on mammalian vitreous gel.

scientific article

Extraction and characterisation of the intact form of bovine vitreous type IX collagen

scientific article published on 01 May 1992

Extraction and characterization of the tissue forms of collagen types II and IX from bovine vitreous.

scientific article published on April 1994

Extraction of the intact form of type IX collagen from mammalian vitreous

scientific article published on 01 November 1991

Fibulin 5 forms a compact dimer in physiological solutions

scientific article

Focus on molecules: opticin

scientific article

Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration

scientific article

Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3

scientific article

Glycan localization within the human interphotoreceptor matrix and photoreceptor inner and outer segments.

scientific article

Glycosidic enzymes enhance retinal transduction following intravitreal delivery of AAV2.

scientific article

Identification in vitreous and molecular cloning of opticin, a novel member of the family of leucine-rich repeat proteins of the extracellular matrix

scientific article

Identification of alternatively spliced variants of type II procollagen in vitreous

scientific article published on 01 August 1994

Identification of factor H-like protein 1 as the predominant complement regulator in Bruch's membrane: implications for age-related macular degeneration.

scientific article published on 10 October 2014

Identification of opticin, a member of the small leucine-rich repeat proteoglycan family, in human articular tissues: a novel target for MMP-13 in osteoarthritis

scientific article published on 4 March 2008

Immunolocalisation of opticin in the human eye

scientific article

Impaired binding of the age-related macular degeneration-associated complement factor H 402H allotype to Bruch's membrane in human retina.

scientific article

Introduction to metabolomics and its applications in ophthalmology.

scientific article published on 18 March 2016

Iron, zinc, and copper in retinal physiology and disease

scientific article

LRRCE: a leucine-rich repeat cysteine capping motif unique to the chordate lineage

scientific article

Lectin binding sites in normal, scarred, and lattice dystrophy corneas

scientific article

Light and X-ray scattering show decorin to be a dimer in solution.

scientific article published on 21 February 2003

Localisation of opticin in human proliferative retinal disease

scientific article

Localization of pN-type IIA procollagen on adult bovine vitreous collagen fibrils

scientific article published on 01 May 2000

Mapping the differential distribution of glycosaminoglycans in the adult human retina, choroid, and sclera

scientific article

Mapping the differential distribution of proteoglycan core proteins in the adult human retina, choroid, and sclera

scientific article

Matrix metalloproteinase-1 associates with intracellular organelles and confers resistance to lamin A/C degradation during apoptosis

scientific article

Matrix metalloproteinases and their natural inhibitors.

scientific article published in October 2000

Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA).

scientific article published on 30 April 2012

Missense and nonsense mutations in the alternatively-spliced exon 2 ofCOL2A1cause the ocular variant of Stickler syndrome

scientific article published on 01 January 2008

Molecular findings from 537 individuals with inherited retinal disease.

scientific article published on 11 May 2016

Neoplastic transformation of ciliary body epithelium is associated with loss of opticin expression

scientific article published on 27 September 2006

No evidence of association between complement factor I genetic variant rs10033900 and age-related macular degeneration

scientific article published on 12 October 2011

Novel mutations in the small leucine-rich repeat protein/proteoglycan (SLRP) genes in high myopia.

scientific article

On the calculation of the binding force between decorin and collagen

scientific article published on 03 March 2006

Ophthalmology in the post-genomic era

scientific article

Opticin binds to heparan and chondroitin sulfate proteoglycans.

scientific article

Opticin exerts its anti-angiogenic activity by regulating extracellular matrix adhesiveness

scientific article

Opticin, a small leucine-rich proteoglycan, is uniquely expressed and translocated to the nucleus of chronic lymphocytic leukemia cells.

scientific article published on 28 August 2013

Opticin: a potent anti-angiogenic/antiproliferative agent for breast cancer therapy

scientific article published on 18 May 2010

Photocoagulation of subfoveal choroidal neovascular membranes in age related macular degeneration: the impact of the macular photocoagulation study in the United Kingdom and Republic of Ireland

scientific article

Pyoderma gangrenosum and necrotising sclerokeratitis

scientific article published on 01 May 1998

Ranibizumab for the management of Sorsby fundus dystrophy

scientific article published on 26 October 2012

Ranibizumab versus bevacizumab to treat neovascular age-related macular degeneration: one-year findings from the IVAN randomized trial

scientific article published on 11 May 2012

Regulation of eye size by the retinal basement membrane and vitreous body

scientific article published in August 2006

Repeatability of visual function measures in age-related macular degeneration.

scientific article published on 25 July 2013

Restoration of Vision with Ectopic Expression of Human Rod Opsin

scientific article published on 28 July 2015

Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration.

scientific article published in January 2015

Routine versus As-Needed Bevacizumab with 12-Weekly Assessment Intervals for Neovascular Age-Related Macular Degeneration

scientific article published in July 2015

Seven new loci associated with age-related macular degeneration

scientific article

Solar retinopathy in a patient with bipolar affective disorder.

scientific article published on February 2006

Species specific membrane anchoring of nyctalopin, a small leucine-rich repeat protein

scientific article published on 19 May 2005

Structural correlations in the family of small leucine-rich repeat proteins and proteoglycans

scientific article published on 19 May 2006

Structural effects of fibulin 5 missense mutations associated with age-related macular degeneration and cutis laxa

scientific article

Structural macromolecules and supramolecular organisation of the vitreous gel.

scientific article

Structure, chromosomal location, and tissue-specific expression of the mouse opticin gene

scientific article

The Royal College of Ophthalmologists Guidelines on AMD: Executive Summary

scientific article published on 25 October 2013

The biochemical structure of mammalian vitreous

scientific article published on January 1996

The introduction of verteporfin photodynamic therapy in the UK: PDT users group (PDTUG) surveillance programme report 1.

scientific article published on 16 March 2007

The large chondroitin sulphate proteoglycan versican in mammalian vitreous

scientific article

The proteoglycan glycomatrix: a sugar microenvironment essential for complement regulation.

scientific article

The role of complement in age-related macular degeneration: heparan sulphate, a ZIP code for complement factor H?

scientific article published on 07 December 2013

The role of extracellular matrix in retinal vascular development and preretinal neovascularization

scientific article published on April 2015

The role of the posterior ciliary body in the biosynthesis of vitreous humour.

scientific article

The vitreous glycoprotein opticin inhibits preretinal neovascularization

scientific journal article

Tissue-specific host recognition by complement factor H is mediated by differential activities of its glycosaminoglycan-binding regions

scientific article

Type VI collagen is present in human and bovine vitreous

scientific article published on 01 November 1996

Vision impairment and dual sensory problems in middle age. ⬇️

scientific article

Vitrectomy for primary symptomatic vitreous opacities: an evidence-based review.

scientific article published on 4 March 2016

Vitreous as a substrate for vitreolysis.

scientific article published on 03 June 2009

Vitreous phenotype: genotype correlation in Stickler syndrome

scientific article published on 01 January 2002

Whole Genome Sequencing Increases Molecular Diagnostic Yield Compared with Current Diagnostic Testing for Inherited Retinal Disease.

scientific article published on 9 February 2016

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