List of works - Christopher Heier

Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice

scientific article

Development of electrocardiogram intervals during growth of FVB/N neonate mice

scientific article

ECG in neonate mice with spinal muscular atrophy allows assessment of drug efficacy.

scientific article published on January 2015

Identification of Pathway-Specific Serum Biomarkers of Response to Glucocorticoid and Infliximab Treatment in Children with Inflammatory Bowel Disease

scientific article published on 15 September 2016

Motor neuron rescue in spinal muscular atrophy mice demonstrates that sensory-motor defects are a consequence, not a cause, of motor neuron dysfunction

scientific article published on March 2012

Multi-Omics Identifies Circulating miRNA and Protein Biomarkers for Facioscapulohumeral Dystrophy

scientific article published on 19 November 2020

Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone

scientific article published on 08 June 2018

Non-invasive MRI and spectroscopy of mdx mice reveal temporal changes in dystrophic muscle imaging and in energy deficits

scientific article

SMN transcript stability: could modulation of messenger RNA degradation provide a novel therapy for spinal muscular atrophy?

scientific article published on August 2007

Selective modulation through the glucocorticoid receptor ameliorates muscle pathology in mdx mice

scientific article

TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy

scientific article published on 26 August 2015

The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models

scientific article

VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice

scientific article

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

scientific article

VBP15, a novel anti-inflammatory, is effective at reducing the severity of murine experimental autoimmune encephalomyelitis.

scientific article published on 13 November 2014

VBP15, a novel dissociative steroid compound, reduces NFκB-induced expression of inflammatory cytokines in vitro and symptoms of murine trinitrobenzene sulfonic acid-induced colitis.

scientific article published on 3 June 2016

Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy

scientific article published on 11 February 2019

Δ-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects.

scientific article

List of works by Christopher Heier

Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice

Development of electrocardiogram intervals during growth of FVB/N neonate mice

ECG in neonate mice with spinal muscular atrophy allows assessment of drug efficacy.

Identification of Pathway-Specific Serum Biomarkers of Response to Glucocorticoid and Infliximab Treatment in Children with Inflammatory Bowel Disease

Motor neuron rescue in spinal muscular atrophy mice demonstrates that sensory-motor defects are a consequence, not a cause, of motor neuron dysfunction

Multi-Omics Identifies Circulating miRNA and Protein Biomarkers for Facioscapulohumeral Dystrophy

Muscle miRNAome shows suppression of chronic inflammatory miRNAs with both prednisone and vamorolone

Non-invasive MRI and spectroscopy of mdx mice reveal temporal changes in dystrophic muscle imaging and in energy deficits

SMN transcript stability: could modulation of messenger RNA degradation provide a novel therapy for spinal muscular atrophy?

Selective modulation through the glucocorticoid receptor ameliorates muscle pathology in mdx mice

TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy

The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models

VBP15, a glucocorticoid analogue, is effective at reducing allergic lung inflammation in mice

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

VBP15, a novel anti-inflammatory, is effective at reducing the severity of murine experimental autoimmune encephalomyelitis.

VBP15, a novel dissociative steroid compound, reduces NFκB-induced expression of inflammatory cytokines in vitro and symptoms of murine trinitrobenzene sulfonic acid-induced colitis.

Vamorolone targets dual nuclear receptors to treat inflammation and dystrophic cardiomyopathy

Δ-9,11 modification of glucocorticoids dissociates nuclear factor-κB inhibitory efficacy from glucocorticoid response element-associated side effects.