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List of works by Olivier Mignen

A new tool to test active ingredient using lactic acid in vitro, a help to understand cellular mechanism involved in stinging test: An example using a bacterial polysaccharide (Fucogel® ).

scientific article published on 27 December 2017

Agonist activation of arachidonate-regulated Ca2+-selective (ARC) channels in murine parotid and pancreatic acinar cells

scientific article

Arachidonate-regulated Ca2+-selective (ARC) channel activity is modulated by phosphorylation and involves an A-kinase anchoring protein.

scientific article published on 30 June 2005

Are Orai1 and Orai3 channels more important than calcium influx for cell proliferation?

scientific article

Both Orai1 and Orai3 are essential components of the arachidonate-regulated Ca2+-selective (ARC) channels.

scientific article published on 8 November 2007

CD5 and B lymphocyte responses: multifaceted effects through multitudes of pathways and channels

scientific article published on 01 July 2020

CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes

scientific article published on 8 August 2016

Ca2+ protein alpha 1D of CaV1.3 regulates intracellular calcium concentration and migration of colon cancer cells through a non-canonical activity

scientific article

Ca2+ selectivity and fatty acid specificity of the noncapacitative, arachidonate-regulated Ca2+ (ARC) channels

scientific article

Calcineurin directs the reciprocal regulation of calcium entry pathways in nonexcitable cells

scientific article published on 21 July 2003

Calcium Increase and Substance P Release Induced by the Neurotoxin Brevetoxin-1 in Sensory Neurons: Involvement of PAR2 Activation through Both Cathepsin S and Canonical Signaling

scientific article published on 17 December 2020

Calcium Signaling: From Normal B Cell Development to Tolerance Breakdown and Autoimmunity.

scientific article

Calcium and Cell Fate.

scientific article published on 2 March 2016

Calcium entry and the control of calcium oscillations

scientific article published on October 1, 2003

Calcium signaling and cell fate: how can Ca2+ signals contribute to wrong decisions for Chronic Lymphocytic Leukemic B lymphocyte outcome?

scientific article published on January 2015

Calumenin contributes to ER-Ca2+ homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention.

scientific article published on 4 February 2017

Carboxyamidotriazole-induced inhibition of mitochondrial calcium import blocks capacitative calcium entry and cell proliferation in HEK-293 cells

scientific article published on December 2005

Characterization of neurons from adult human skin-derived precursors in serum-free medium : a PCR array and immunocytological analysis

scientific article published in March 2012

Chloride and non-selective cation channels in unstimulated trout red blood cells

scientific article published in August 1998

Constitutive calcium entry and cancer: updated views and insights.

scientific article

Dysregulated Lymphoid Cell Populations in Mouse Models of Systemic Lupus Erythematosus.

scientific article

Function and regulation of TRPM7, as well as intracellular magnesium content, are altered in cells expressing ΔF508-CFTR and G551D-CFTR.

scientific article

High glucose-induced apoptosis through store-operated calcium entry and calcineurin in human umbilical vein endothelial cells

scientific article published on 21 October 2005

High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies

scientific journal article

Major role for TRPV1 and InsP3R in PAR-2-elicited inflammatory mediator production in differentiated human keratinocytes.

scientific article published on 16 February 2018

Measuring Calumenin Impact on ER-Calcium Depletion Using Transient Calumenin Overexpression and Silencing

scientific article published on 01 January 2019

Molecular Dynamics Simulations of Membrane-Bound STIM1 to Investigate Conformational Changes during STIM1 Activation upon Calcium Release.

scientific article published on 2 February 2017

Orai1 subunit stoichiometry of the mammalian CRAC channel pore.

scientific article published on 15 November 2007

Overexpression of certain transient receptor potential and Orai channels in prostate cancer is associated with decreased risk of systemic recurrence after radical prostatectomy

scientific article published on 02 September 2019

Permeation of monovalent cations through the non-capacitative arachidonate-regulated Ca2+ channels in HEK293 cells. Comparison with endogenous store-operated channels.

scientific article published on 2 April 2001

Preliminary Structure-Activity Relationship (SAR) of a Novel Series of Pyrazole SKF-96365 Analogues as Potential Store-Operated Calcium Entry (SOCE) Inhibitors

scientific article published on 14 March 2018

Proteomic identification of calumenin as a G551D-CFTR associated protein

scientific article

Reciprocal regulation of capacitative and arachidonate-regulated noncapacitative Ca2+ entry pathways.

scientific article

SERCA and PMCA pumps contribute to the deregulation of Ca2+ homeostasis in human CF epithelial cells.

scientific article

SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline

scientific article

STIM1 and the noncapacitative ARC channels

scientific article

STIM1 at the plasma membrane as a new target in progressive chronic lymphocytic leukemia

scientific article published on 23 April 2019

STIM1 regulates Ca2+ entry via arachidonate-regulated Ca2+-selective (ARC) channels without store depletion or translocation to the plasma membrane

scientific article published on 07 December 2006

Sustained calcium signalling and caspase-3 activation involve NMDA receptors in thymocytes in contact with dendritic cells.

scientific article

The ARC channel--an endogenous store-independent Orai channel

scientific article published in January 2013

The N-terminal domain of Orai3 determines selectivity for activation of the store-independent ARC channel by arachidonic acid.

scientific article

The Orai1 severe combined immune deficiency mutation and calcium release-activated Ca2+ channel function in the heterozygous condition.

scientific article

The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis.

scientific article published on 23 January 2017

Volume regulation following hypotonic shock in isolated crypts of mouse distal colon

scientific article published on 01 March 1999