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List of works by Sven Diederichs

A Rap GTPase interactor, RADIL, mediates migration of neural crest precursors

scientific article

A cautionary tale of sense-antisense gene pairs: independent regulation despite inverse correlation of expression

scientific article published on 20 October 2017

A functional yeast survival screen of tumor-derived cDNA libraries designed to identify anti-apoptotic mammalian oncogenes

scientific article

A high-throughput screen identifies the long non-coding RNA DRAIC as a regulator of autophagy

scientific article published on 14 March 2019

A novel long non-coding RNA from NBL2 pericentromeric macrosatellite forms a perinucleolar aggregate structure in colon cancer.

scientific article published in June 2018

A pan-cancer analysis of synonymous mutations

scientific article published on 12 June 2019

A pan-cancer analysis reveals nonstop extension mutations causing SMAD4 tumour suppressor degradation

scientific article published on 27 July 2020

A systemic transcriptome analysis reveals the regulation of neural stem cell maintenance by an E2F1-miRNA feedback loop

scientific article published on 8 February 2013

Adjuvant therapy with small hairpin RNA interference prevents non-small cell lung cancer metastasis development in mice

scientific article

Alternative splicing affects the subcellular localization of Drosha

scientific article published on 16 May 2016

Analyses of the genomic methylation status of the human cyclin A1 promoter by a novel real-time PCR-based methodology

scientific article

Analysis of the genetic interactions between Cyclin A1, Atm and p53 during spermatogenesis

scientific article published on 01 November 2007

Arginine vasopressin-dependent and AVP-independent mechanisms of renal fluid absorption during thirsting despite glucocorticoid-mediated vasopressin suppression.

scientific article

Argonaute proteins regulate microRNA stability: Increased microRNA abundance by Argonaute proteins is due to microRNA stabilization

scientific article published on 01 November 2011

Argonaute-3 activates the let-7a passenger strand microRNA.

scientific article published on 02 October 2013

Cell-type specific regulation of the human 11beta-hydroxysteroid dehydrogenase type 1 promoter

scientific article

Challenges of CRISPR/Cas9 applications for long non-coding RNA genes.

scientific article

Coexpression of Argonaute-2 enhances RNA interference toward perfect match binding sites

scientific article

Cyclin A1 and gametogenesis in fertile and infertile patients: a potential new molecular diagnostic marker

scientific article published in September 2002

Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function

scientific article (publication date: April 2001)

Cyclin A1 is highly expressed in aggressive testicular germ cell tumors

scientific article published on 01 February 2003

Cyclin A1, the alternative A-type cyclin, contributes to G1/S cell cycle progression in somatic cells

scientific article

DNA damage response involves modulation of Ku70 and Rb functions by cyclin A1 in leukemia cells

scientific article published on August 2007

Designer epigenome modifiers enable robust and sustained gene silencing in clinically relevant human cells

scientific article published on 10 March 2018

Detection of functionally active melanocortin receptors and evidence for an immunoregulatory activity of alpha-melanocyte-stimulating hormone in human dermal papilla cells

scientific article published on 4 August 2005

Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression.

scientific article published in December 2007

Epigenetic inactivation of the p53-induced long noncoding RNA TP53 target 1 in human cancer

scientific article

Epigenetically deregulated microRNA-375 is involved in a positive feedback loop with estrogen receptor alpha in breast cancer cells

scientific article

Evaluation of fluorescence in situ hybridization techniques to study long non-coding RNA expression in cultured cells

scientific article

Expression patterns of mitotic and meiotic cell cycle regulators in testicular cancer and development.

scientific article published in August 2005

From junk to master regulators of invasion: lncRNA functions in migration, EMT and metastasis

scientific article published on 15 February 2016

Functionally defective germline variants of sialic acid acetylesterase in autoimmunity

scientific article

Generation of murine tumor cell lines deficient in MHC molecule surface expression using the CRISPR/Cas9 system

scientific article

Genome-wide methylation screen in low-grade breast cancer identifies novel epigenetically altered genes as potential biomarkers for tumor diagnosis.

scientific article published on 28 August 2012

Identification of interaction partners and substrates of the cyclin A1-CDK2 complex

scientific article published on 24 May 2004

Identification of metastasis-associated receptor tyrosine kinases in non-small cell lung cancer

scientific article

Identification, quantification and bioinformatic analysis of RNA-dependent proteins by RNase treatment and density gradient ultracentrifugation using R-DeeP

scientific article published on 24 February 2020

Inhibitor of cyclin-dependent kinase (CDK) interacting with cyclin A1 (INCA1) regulates proliferation and is repressed by oncogenic signaling

scientific article

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma

article

Invasion front-specific expression and prognostic significance of microRNA in colorectal liver metastases

scientific article

LIMT is a novel metastasis inhibiting lncRNA suppressed by EGF and downregulated in aggressive breast cancer

scientific article published on August 2016

LINC00261 and the Adjacent Gene FOXA2 Are Epithelial Markers and Are Suppressed during Lung Cancer Tumorigenesis and Progression

scientific article published on 28 December 2018

Long Noncoding RNAs in Lung Cancer

scientific article published on 03 June 2015

Long noncoding RNA HOTTIP/HOXA13 expression is associated with disease progression and predicts outcome in hepatocellular carcinoma patients

scientific article

Long noncoding RNA: "LNCs" to cancer

scientific article published on 31 January 2014

Loop-miRs: active microRNAs generated from single-stranded loop regions

scientific article published on 10 April 2013

Loss of expression of HDAC-recruiting methyl-CpG-binding domain proteins in human cancer

scientific article

Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development

scientific article published on August 2012

Many roads to maturity: microRNA biogenesis pathways and their regulation

scientific article (publication date: March 2009)

Methylation of the cyclin A1 promoter correlates with gene silencing in somatic cell lines, while tissue-specific expression of cyclin A1 is methylation independent

scientific article

Micro-terminator: 'Hasta la vista, lncRNA!'

scientific article published on 01 April 2015

MicroRNA Northern blotting, precursor cloning, and Ago2-improved RNA interference.

scientific article

MicroRNA biogenesis and cancer

scientific article published on 01 January 2011

Mitochondrial mutations in human cancer: Curation of translation

scientific article published on 5 September 2017

Mitotic Diversity in Homeostatic Human Interfollicular Epidermis

scientific article published on 28 January 2016

Molecular biology: Rap and chirp about X inactivation

scientific article published in May 2015

Non-coding RNA and disease

scientific article published on 01 June 2012

Non-coding RNA in hepatocellular carcinoma: Mechanisms, biomarkers and therapeutic targets

scientific article

Noncoding RNA gene silencing through genomic integration of RNA destabilizing elements using zinc finger nucleases

scientific article

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1).

scientific article

Pulmonary metastasectomy for thyroid cancer as salvage therapy for radioactive iodine-refractory metastases

scientific article published on 30 October 2017

R-DeeP: Proteome-wide and Quantitative Identification of RNA-Dependent Proteins by Density Gradient Ultracentrifugation

scientific article published on 07 May 2019

RNA meets disease in paradise

scientific article published in November 2011

RNA motifs and combinatorial prediction of interactions, stability and localization of noncoding RNAs

scientific article published on 12 November 2018

RNA-binding proteins regulate the expression of the immune activating ligand MICB.

scientific article published on 13 June 2014

Risk factors associated with a low glomerular filtration rate in primary aldosteronism

scientific article

Rosiglitazone decreases 11beta-hydroxysteroid dehydrogenase type 1 in subcutaneous adipose tissue.

scientific article published on 6 June 2007

S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer

scientific article

Self-assembly is important for TIP47 function in mannose 6-phosphate receptor transport

scientific article (publication date: 2003)

Sequence variations of microRNAs in human cancer: alterations in predicted secondary structure do not affect processing.

scientific article published on June 2006

Systematic analysis of migration factors by MigExpress identifies essential cell migration control genes in non-small cell lung cancer

scientific article published on 14 May 2021

Targeting LINC00673 expression triggers cellular senescence in lung cancer

scientific article published on 07 December 2018

The Circular RNA Landscape of Non-Small Cell Lung Cancer Cells

scientific article published on 28 April 2020

The Long Noncoding RNA Cancer Susceptibility 9 and RNA Binding Protein Heterogeneous Nuclear Ribonucleoprotein L Form a Complex and Coregulate Genes Linked to AKT Signaling

scientific article published on 12 October 2018

The cancer-associated microprotein CASIMO1 controls cell proliferation and interacts with squalene epoxidase modulating lipid droplet formation

scientific article published on 16 May 2018

The cyclin A1-CDK2 complex regulates DNA double-strand break repair.

scientific article published on October 2004

The dark matter of the cancer genome: aberrations in regulatory elements, untranslated regions, splice sites, non-coding RNA and synonymous mutations

scientific article

The diagnosis and treatment of primary hyperaldosteronism in Germany: results on 555 patients from the German Conn Registry

scientific article published on May 2009

The four dimensions of noncoding RNA conservation.

scientific article published on 07 March 2014

The hallmarks of cancer: a long non-coding RNA point of view.

scientific article

The lncRNA VELUCT strongly regulates viability of lung cancer cells despite its extremely low abundance.

scientific article

The lncRNA lincNMR regulates nucleotide metabolism via a YBX1 - RRM2 axis in cancer

scientific article published on 25 June 2020

The long non-coding RNA LINC00152 is essential for cell cycle progression through mitosis in HeLa cells

scientific article

The noncoding RNA MALAT1 is a critical regulator of the metastasis phenotype of lung cancer cells

scientific article

Translocation products in acute myeloid leukemia activate the Wnt signaling pathway in hematopoietic cells.

scientific article published on April 2004

Tumor suppressive microRNAs miR-34a/c control cancer cell expression of ULBP2, a stress-induced ligand of the natural killer cell receptor NKG2D.

scientific article

Tumor-derived exosomes modulate PD-L1 expression in monocytes.

scientific article published in July 2017

[Non-coding RNA in malignant tumors. A new world of tumor biomarkers and target structures in cancer cells]

scientific article published on 01 October 2010

circ2GO: A Database Linking Circular RNAs to Gene Function

scientific article published on 14 October 2020

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