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List of works by Nacho Aguilo

A human dendritic cell-based in vitro model to assess Mycobacterium tuberculosis SO2 vaccine immunogenicity

scientific article published on 20 May 2014

A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component

scientific article

Antigen-specific primed cytotoxic T cells eliminate tumour cells in vivo and prevent tumour development, regardless of the presence of anti-apoptotic mutations conferring drug resistance.

scientific article published on 9 May 2018

Attenuated Mycobacterium tuberculosis SO2 vaccine candidate is unable to induce cell death.

scientific article

Autoimmune lymphoproliferative syndrome (ALPS) in a patient with a new germline Fas gene mutation

article

Bim is a crucial regulator of apoptosis induced by Mycobacterium tuberculosis.

scientific article

Breaking Transmission with Vaccines: The Case of Tuberculosis.

scientific article published on July 2017

Cell cycle regulation by FasL and Apo2L/TRAIL in human T-cell blasts. Implications for autoimmune lymphoproliferative syndromes.

scientific article published on 15 May 2008

ERK5 knockdown generates mouse leukemia cells with low MHC class I levels that activate NK cells and block tumorigenesis.

scientific article

ESX-1-induced apoptosis during mycobacterial infection: to be or not to be, that is the question

scientific article

ESX-1-induced apoptosis is involved in cell-to-cell spread of Mycobacterium tuberculosis

scientific article published on 2 August 2013

Elucidating sources and roles of granzymes A and B during bacterial infection and sepsis

scientific article published on 10 July 2014

Evaluation of the Mycobacterium tuberculosis SO2 vaccine using a natural tuberculosis infection model in goats.

scientific article published on 3 May 2017

Evaluation of the immunogenicity and diagnostic interference caused by M. tuberculosis SO2 vaccination against tuberculosis in goats.

scientific article published on 25 September 2015

Granzyme A Is Expressed in Mouse Lungs during Mycobacterium tuberculosis Infection but Does Not Contribute to Protection In Vivo

scientific article

Granzyme B of cytotoxic T cells induces extramitochondrial reactive oxygen species production via caspase-dependent NADPH oxidase activation.

scientific article

Human NK cells activated by EBV(+) lymphoblastoid cells overcome anti-apoptotic mechanisms of drug resistance in haematological cancer cells.

scientific article published on 9 January 2015

Hyper-attenuated MTBVAC erp mutant protects against tuberculosis in mice

scientific article

IFNα signaling through PKC-θ is essential for antitumor NK cell function

scientific article

IL-17-dependent SIgA-mediated protection against nasal Bordetella pertussis infection by live attenuated BPZE1 vaccine

scientific article published on 16 August 2018

Impaired anti-leukemic immune response in PKCtheta-deficient mice

scientific article published on 06 May 2008

Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference

scientific article published on 21 December 2020

Klebsiella pneumoniae survives within macrophages by avoiding delivery to lysosomes

scientific article published on 4 June 2015

MHC-I modulation due to changes in tumor cell metabolism regulates tumor sensitivity to CTL and NK cells

scientific article

MTBVAC from discovery to clinical trials in tuberculosis-endemic countries

scientific article

MTBVAC vaccine is safe, immunogenic and confers protective efficacy against Mycobacterium tuberculosis in newborn mice

scientific article published on 30 November 2015

MTBVAC-Based TB-HIV Vaccine Is Safe, Elicits HIV-T Cell Responses, and Protects against in Mice

article

MTBVAC: Attenuating the Human Pathogen of Tuberculosis (TB) Toward a Promising Vaccine against the TB Epidemic.

scientific article

Mitochondrial respiratory chain and thioredoxin reductase regulate intermembrane Cu,Zn-superoxide dismutase activity: implications for mitochondrial energy metabolism and apoptosis

scientific journal article

Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion

scientific article

Mycobacterium tuberculosis infection prevents asthma and abrogates eosinophilopoiesis in an experimental model

scientific article published on 14 June 2019

New insights into the transposition mechanisms of IS6110 and its dynamic distribution between Mycobacterium tuberculosis Complex lineages.

scientific article published on 12 April 2018

Oxidative phosphorylation induces de novo expression of the MHC class I in tumor cells through the ERK5 pathway.

scientific article published on 20 August 2010

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

scientific article published on 19 September 2016

Protective immunity afforded by attenuated, PhoP-deficient Mycobacterium tuberculosis is associated with sustained generation of CD4+ T-cell memory

scientific article published on 27 December 2011

Protein kinase C-theta is required for NK cell activation and in vivo control of tumor progression.

scientific article published in February 2009

Pulmonary Mycobacterium bovis BCG vaccination confers dose-dependent superior protection compared to that of subcutaneous vaccination

scientific article published on 5 February 2014

Pulmonary but Not Subcutaneous Delivery of BCG Vaccine Confers Protection to Tuberculosis-Susceptible Mice by an Interleukin 17-Dependent Mechanism.

scientific article published on 22 October 2015

Reactogenicity to major tuberculosis antigens absent in BCG is linked to improved protection against Mycobacterium tuberculosis

scientific article

Recent developments in tuberculosis vaccines

article

The induction of Bim expression in human T-cell blasts is dependent on nonapoptotic Fas/CD95 signaling

scientific article published on 24 October 2006

Therapeutic efficacy of the live-attenuated Mycobacterium tuberculosis vaccine, MTBVAC, in a preclinical model of bladder cancer.

scientific article published on 6 April 2018

Vacunación frente a tuberculosis

scientific article published on 05 April 2018

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