List of works - Eva-María Priego

5'-O-Tritylated Nucleoside Derivatives: Inhibition of Thymidine Phosphorylase and Angiogenesis

scientific article published on 04 May 2006

5‘-O-Tritylinosine and Analogues as Allosteric Inhibitors of Human Thymidine Phosphorylase

scientific article published on 01 September 2006

9-Arylpurines as a novel class of enterovirus inhibitors.

scientific article

A New Photoactive and Highly Soluble C60−TTF−C60Dimer: Charge Separation and Recombination

scientific article published on 01 December 2000

Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase

scientific article published in January 2002

Antivascular and antitumor properties of the tubulin-binding chalcone TUB091

scientific article

Antiviral activity of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones against chikungunya virus targeting the viral capping nsP1.

scientific article published on 12 June 2017

Blocking Blood Flow to Solid Tumors by Destabilizing Tubulin: An Approach to Targeting Tumor Growth.

scientific article published on 27 June 2016

Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia

scientific article published on 26 February 2019

Chikungunya virus drug discovery: still a long way to go?

scientific article published on 14 June 2019

Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity.

scientific article published on 10 February 2018

Design and Synthesis of New 6-Nitro and 6-Amino-3,3a,4,5-Tetrahydro-2H-Benzo[g]indazole Derivatives: Antiproliferative and Antibacterial Activity

scientific article published on 21 November 2019

Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the αT5 loop

scientific article published on 21 March 2019

Efficient synthesis and anti-enteroviral activity of 9-arylpurines

scientific article published on 17 January 2012

Genome bioinformatic analysis of nonsynonymous SNPs

scientific article

High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.

scientific article published on 9 March 2018

Identification of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones as novel inhibitors of Chikungunya virus replication

scientific article

Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation.

scientific article published on 12 March 2018

Inhibition of the Replication of Different Strains of Chikungunya Virus by 3-Aryl-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones.

scientific article

Intramolecular cation-pi interactions as the driving force to restrict the conformation of certain nucleosides

scientific article published in March 2010

Microwave-assisted synthesis of C-8 aryl and heteroaryl inosines and determination of their inhibitory activities against Plasmodium falciparum purine nucleoside phosphorylase.

scientific article

Mitochondrial thymidine kinase inhibitors

scientific article

Novel colchicine-site binders with a cyclohexanedione scaffold identified through a ligand-based virtual screening approach

scientific article published on 9 May 2014

Pyrido[2,1-f]purine-2,4-dione derivatives as a novel class of highly potent human A(3) adenosine receptor antagonists.

scientific article

Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations.

scientific article published on January 2004

Selective human adenosine A3 antagonists based on pyrido[2,1-f]purine-2,4-diones: novel features of hA3 antagonist binding.

scientific article

Structure, physiological role, and specific inhibitors of human thymidine kinase 2 (TK2): present and future.

scientific article published on September 2008

Synthesis and antiproliferative activity of 6-phenylaminopurines.

scientific article published on 30 September 2014

Synthesis and evaluation of thymine-derived carboxamides against mitochondrial thymidine kinase (TK-2) and related enzymes

scientific article published in October 2004

Synthesis and radical coupling of pyridine-bridged pi-extended tetrathiafulvalene (TTF)-type donors and push-pull analogues.

scientific article

The crystal structure of the BAR domain from human Bin1/amphiphysin II and its implications for molecular recognition

scientific article published in October 2006

Thymidine phosphorylase inhibitors: recent developments and potential therapeutic applications

scientific article

Thymidine phosphorylase is noncompetitively inhibited by 5'-O-trityl-inosine (KIN59) and related compounds.

scientific article

Towards new thymidine phosphorylase/PD-ECGF inhibitors based on the transition state of the enzyme reaction

scientific article published in May 2003

List of works by Eva-María Priego

5'-O-Tritylated Nucleoside Derivatives: Inhibition of Thymidine Phosphorylase and Angiogenesis

5‘-O-Tritylinosine and Analogues as Allosteric Inhibitors of Human Thymidine Phosphorylase

9-Arylpurines as a novel class of enterovirus inhibitors.

A New Photoactive and Highly Soluble C60−TTF−C60Dimer: Charge Separation and Recombination

Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase

Antivascular and antitumor properties of the tubulin-binding chalcone TUB091

Antiviral activity of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones against chikungunya virus targeting the viral capping nsP1.

Blocking Blood Flow to Solid Tumors by Destabilizing Tubulin: An Approach to Targeting Tumor Growth.

Chalcones and Chalcone-mimetic Derivatives as Notch Inhibitors in a Model of T-cell Acute Lymphoblastic Leukemia

Chikungunya virus drug discovery: still a long way to go?

Conformational mimetics of the α-methyl chalcone TUB091 binding tubulin: Design, synthesis and antiproliferative activity.

Design and Synthesis of New 6-Nitro and 6-Amino-3,3a,4,5-Tetrahydro-2H-Benzo[g]indazole Derivatives: Antiproliferative and Antibacterial Activity

Diphenyl ether derivatives occupy the expanded binding site of cyclohexanedione compounds at the colchicine site in tubulin by movement of the αT5 loop

Efficient synthesis and anti-enteroviral activity of 9-arylpurines

Genome bioinformatic analysis of nonsynonymous SNPs

High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design.

Identification of [1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones as novel inhibitors of Chikungunya virus replication

Identification of a novel 2-oxindole fluorinated derivative as in vivo antitumor agent for prostate cancer acting via AMPK activation.

Inhibition of the Replication of Different Strains of Chikungunya Virus by 3-Aryl-[1,2,3]triazolo[4,5-d]pyrimidin-7(6H)-ones.

Intramolecular cation-pi interactions as the driving force to restrict the conformation of certain nucleosides

Microwave-assisted synthesis of C-8 aryl and heteroaryl inosines and determination of their inhibitory activities against Plasmodium falciparum purine nucleoside phosphorylase.

Mitochondrial thymidine kinase inhibitors

Novel colchicine-site binders with a cyclohexanedione scaffold identified through a ligand-based virtual screening approach

Pyrido[2,1-f]purine-2,4-dione derivatives as a novel class of highly potent human A(3) adenosine receptor antagonists.

Role of histidine-85 in the catalytic mechanism of thymidine phosphorylase as assessed by targeted molecular dynamics simulations and quantum mechanical calculations.

Selective human adenosine A3 antagonists based on pyrido[2,1-f]purine-2,4-diones: novel features of hA3 antagonist binding.

Structure, physiological role, and specific inhibitors of human thymidine kinase 2 (TK2): present and future.

Synthesis and antiproliferative activity of 6-phenylaminopurines.

Synthesis and evaluation of thymine-derived carboxamides against mitochondrial thymidine kinase (TK-2) and related enzymes

Synthesis and radical coupling of pyridine-bridged pi-extended tetrathiafulvalene (TTF)-type donors and push-pull analogues.

The crystal structure of the BAR domain from human Bin1/amphiphysin II and its implications for molecular recognition

Thymidine phosphorylase inhibitors: recent developments and potential therapeutic applications

Thymidine phosphorylase is noncompetitively inhibited by 5'-O-trityl-inosine (KIN59) and related compounds.

Towards new thymidine phosphorylase/PD-ECGF inhibitors based on the transition state of the enzyme reaction