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List of works by Lise Willems

APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis

scientific article published on 18 February 2016

Architectural and functional heterogeneity of hematopoietic stem/progenitor cells in non-del(5q) myelodysplastic syndromes.

scientific article published on 16 November 2016

Autocrine IGF-1/IGF-1R signaling is responsible for constitutive PI3K/Akt activation in acute myeloid leukemia: therapeutic value of neutralizing anti-IGF-1R antibody

scientific article

Clostridium difficile Infection after Allogeneic Hematopoietic Stem Cell Transplantation: Incidence, Risk Factors, and Outcome

scientific article published on 28 February 2012

Dual inhibition of PI3K and mTORC1/2 signaling by NVP-BEZ235 as a new therapeutic strategy for acute myeloid leukemia.

scientific article published on 30 September 2010

High risk of cardiac dysfunction after treatment of secondary acute myeloid leukaemia to breast cancer

scientific article published on 27 January 2009

High risk of cardiac dysfunction after treatment of secondary acute myeloid leukemia following chemotherapy and radiotherapy for breast cancer

scientific article published in February 2010

Inhibiting glutamine uptake represents an attractive new strategy for treating acute myeloid leukemia.

scientific article published on 06 September 2013

IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia

scientific article published on 29 July 2010

Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways.

scientific article

Perspectives on inhibiting mTOR as a future treatment strategy for hematological malignancies

scientific article published on 12 August 2010

Primary bone diffuse large B-cell lymphoma: a retrospective evaluation on 76 cases from French institutional and LYSA studies

scientific article published on 27 April 2016

Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia.

scientific article

Rescue therapy with romiplostim for refractory primary immune thrombocytopenia during pregnancy

scientific article

Role of the PI3K/AKT and mTOR signaling pathways in acute myeloid leukemia.

scientific article

Skin Microvascular Thrombosis in Fusarium Infection in Two Early Biopsied Cases

scientific article

Successful outcome of a disseminated adenovirus infection 6 years after allogeneic bone marrow transplantation

scientific article published on 19 November 2007

Successful treatment of l-asparaginase-induced severe acute hepatotoxicity using mitochondrial cofactors

scientific article published on 14 November 2013

Sustained leukemia-free state and molecular response to sorafenib in a patient with chronic myelomonocytic leukemia in transformation driven by homozygous FLT3-ITD malignant hematopoiesis.

scientific article

Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition

scientific article

The LKB1/AMPK signaling pathway has tumor suppressor activity in acute myeloid leukemia through the repression of mTOR-dependent oncogenic mRNA translation

scientific article published on 28 July 2010

The dual mTORC1 and mTORC2 inhibitor AZD8055 has anti-tumor activity in acute myeloid leukemia.

scientific article published on 6 December 2011

The eukaryotic initiating factor 4E protein is overexpressed, but its level has no prognostic impact in acute myeloid leukaemia.

scientific article published on 14 October 2011