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List of works by Heidi Welch

A Rac1-independent role for P-Rex1 in melanoblasts

scientific article published on 30 July 2014

Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.

scientific article

Characterization of the Rac guanine nucleotide exchange factor P-Rex1 in platelets

scientific article

Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase

scientific article

Expression of Azurophil and specific granule proteins during differentiation of NB4 cells in neutrophils ⬇️

scientific article published on May 1, 1998

Gbetagammas and the Ras binding domain of p110gamma are both important regulators of PI(3)Kgamma signalling in neutrophils

scientific article published on 15 October 2006

Hck Is Activated by Opsonized Zymosan and A23187 in Distinct Subcellular Fractions of Human Granulocytes

scientific article published in Journal of Biological Chemistry

Integrin activation by P-Rex1 is required for selectin-mediated slow leukocyte rolling and intravascular crawling

scientific article published on 23 January 2013

Lyn and Fgr are activated in distinct membrane fractions of human granulocytic cells ⬇️

scientific article published on October 23, 1997

Membrane translocation of P-Rex1 is mediated by G protein betagamma subunits and phosphoinositide 3-kinase

scientific article

Nonreceptor Protein-Tyrosine Kinases in Neutrophil Activation

scientific article published on 01 June 1996

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.

scientific article published on 23 December 2014

P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses

scientific journal article

P-Rex1 cooperates with PDGFRβ to drive cellular migration in 3D microenvironments

scientific article

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils

scientific article published on 21 March 2014

P-Rex1 is required for efficient melanoblast migration and melanoma metastasis

scientific article

P-Rex1, a PtdIns(3,4,5)P3- and Gbetagamma-regulated guanine-nucleotide exchange factor for Rac

scientific article

P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination

scientific article

P-Rex2, a new guanine-nucleotide exchange factor for Rac

scientific article

PI 3-kinase

scientific article published on 01 November 1998

PI3K and RAC signalling in leukocyte and cancer cell migration.

scientific article published on May 2006

Phosphoinositide 3-kinase-dependent activation of Rac.

scientific article

Protein Kinase B and Rac Are Activated in Parallel within a Phosphatidylinositide 3OH-kinase-controlled Signaling Pathway ⬇️

scientific article published on May 1, 1998

PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis

scientific article published on 23 October 2020

Purification of P-Rex1 from neutrophils and nucleotide exchange assay

scientific article

Rac-GTPases and Rac-GEFs in neutrophil adhesion, migration and recruitment

scientific article published on 11 May 2018

Regulation and function of P-Rex family Rac-GEFs

scientific article

Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits

scientific article

Signalling via phosphoinositide 3OH kinases.

scientific article published on November 1997

The Rac-FRET mouse reveals tight spatiotemporal control of Rac activity in primary cells and tissues

scientific article published on 13 March 2014

The guanine-nucleotide-exchange factor P-Rex1 is activated by protein phosphatase 1α.

scientific article

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