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List of works by Alejandro Brun

A DNA vaccine encoding ubiquitinated Rift Valley fever virus nucleoprotein provides consistent immunity and protects IFNAR(-/-) mice upon lethal virus challenge.

scientific article published on 5 May 2011

A protective bivalent vaccine against Rift Valley fever and bluetongue

scientific article published on 30 July 2020

A single immunization with MVA expressing GnGc glycoproteins promotes epitope-specific CD8+-T cell activation and protects immune-competent mice against a lethal RVFV infection

scientific article published on 11 July 2013

Altered lymphocyte homeostasis after oral prion infection in mouse

scientific article published on 07 December 2007

An African swine fever virus gene with similarity to the T-lymphocyte surface antigen CD2 mediates hemadsorption.

scientific article

Antigen delivery systems for veterinary vaccine development. Viral-vector based delivery systems

scientific article published on December 2008

Bead-based suspension array for simultaneous detection of antibodies against the Rift Valley fever virus nucleocapsid and Gn glycoprotein ⬇️

scientific article published on March 16, 2012

Chimpanzee Adenovirus Vaccine Provides Multispecies Protection against Rift Valley Fever

scientific article published on 5 February 2016

Current strategies for subunit and genetic viral veterinary vaccine development.

scientific article published on 21 February 2011

DNA vaccination can break immunological tolerance to PrP in wild-type mice and attenuates prion disease after intracerebral challenge

scientific article published on October 2006

DNA vaccination regimes against Schmallenberg virus infection in IFNAR-/- mice suggest two targets for immunization.

scientific article published on 21 February 2017

Design and construction of African swine fever virus chimeras incorporating foreign viral epitopes.

scientific article published on January 1999

Detection and identification of Rift Valley fever virus in mosquito vectors by quantitative real-time PCR.

scientific article published on 25 July 2012

Different behavior toward bovine spongiform encephalopathy infection of bovine prion protein transgenic mice with one extra repeat octapeptide insert mutation.

scientific article published in March 2004

Discrimination of sheep susceptible and resistant to transmissible spongiform encephalopathies by an haplotype specific monoclonal antibody

scientific article published on 05 July 2007

Distribution of the cellular prion protein (PrPC) in brains of livestock and domesticated species

scientific article published on 7 September 2006

Early detection of PrPres in BSE-infected bovine PrP transgenic mice

scientific article published in April 2003

Efficacy assessment of an MVA vectored Rift Valley Fever vaccine in lambs

scientific article published on 14 June 2014

Efficacy of different DNA and MVA prime-boost vaccination regimens against a Rift Valley fever virus (RVFV) challenge in sheep 12 weeks following vaccination

scientific article published on 21 February 2018

Elements modulating the prion species barrier and its passage consequences

scientific article (publication date: 2014)

European ring trial to evaluate ELISAs for the diagnosis of infection with Rift Valley fever virus

scientific article published on 26 September 2012

Experimental infection of young adult European breed sheep with Rift Valley fever virus field isolates.

scientific article published on October 2010

Generation and application of monoclonal antibodies against Rift Valley fever virus nucleocapsid protein NP and glycoproteins Gn and Gc.

scientific article published on 8 October 2013

Genomics of Viruses

High-yield expression of a viral peptide vaccine in transgenic plants

scientific article

Immunization with DNA Plasmids Coding for Crimean-Congo Hemorrhagic Fever Virus Capsid and Envelope Proteins and/or Virus-Like Particles Induces Protection and Survival in Challenged Mice

scientific article

Immunogenicity and efficacy of a chimpanzee adenovirus-vectored Rift Valley fever vaccine in mice

scientific article

Lethal Mutagenesis of Rift Valley Fever Virus Induced by Favipiravir

scientific article published in 2019

Lymphoplasmacytic Endotheliitis and Anterior Uveitis in Sheep Infected Experimentally with Rift Valley Fever Virus ⬇️

scientific article published on May 24, 2011

MVA Vectored Vaccines Encoding Rift Valley Fever Virus Glycoproteins Protect Mice against Lethal Challenge in the Absence of Neutralizing Antibody Responses

scientific article published on 12 February 2020

Microspheres-prime/rMVA-boost vaccination enhances humoral and cellular immune response in IFNAR(-/-) mice conferring protection against serotypes 1 and 4 of bluetongue virus.

scientific article published on 16 March 2017

Modeling Arboviral Infection in Mice Lacking the Interferon Alpha/Beta Receptor

scientific article published on 08 January 2019

Pathological Characterization Of IFNAR(-/-) Mice Infected With Bluetongue Virus Serotype 4

scientific article

Potential application of silver nanoparticles to control the infectivity of Rift Valley fever virus in vitro and in vivo

scientific article

Priming with DNA plasmids encoding the nucleocapsid protein and glycoprotein precursors from Rift Valley fever virus accelerates the immune responses induced by an attenuated vaccine in sheep.

scientific article

Protection against Rift Valley fever virus infection in mice upon administration of interferon-inducing RNA transcripts from the FMDV genome

scientific article published on 25 June 2014

Protection against lethal Rift Valley fever virus (RVFV) infection in transgenic IFNAR(-/-) mice induced by different DNA vaccination regimens.

scientific article published on 25 February 2010

Proteinase K enhanced immunoreactivity of the prion protein-specific monoclonal antibody 2A11.

scientific article

Recombinant Rift Valley fever viruses encoding bluetongue virus (BTV) antigens: Immunity and efficacy studies upon a BTV-4 challenge

scientific article published on 04 December 2020

Reduced susceptibility to bovine spongiform encephalopathy prions in transgenic mice expressing a bovine PrP with five octapeptide repeats.

scientific article

Rift valley fever: recent insights into pathogenesis and prevention

scientific article

Subclinical bovine spongiform encephalopathy infection in transgenic mice expressing porcine prion protein.

scientific article published in May 2004

Transgenic mice expressing bovine PrP with a four extra repeat octapeptide insert mutation show a spontaneous, non-transmissible, neurodegenerative disease and an expedited course of BSE infection.

scientific article published on 19 October 2005

Understanding Rift Valley fever: contributions of animal models to disease characterization and control

scientific article published on 26 February 2015

Vaccines and Vaccination for Veterinary Viral Diseases: A General Overview.

scientific article published on January 2016

Vertical transmission of bovine spongiform encephalopathy prions evaluated in a transgenic mouse model.

scientific article

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