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List of works by Andrew S Murkin

A beta-fluoroamine inhibitor of purine nucleoside phosphorylase

scientific article published in September 2008

Alteration of the Flexible Loop in 1-Deoxy- d -xylulose-5-phosphate Reductoisomerase Boosts Enthalpy-Driven Inhibition by Fosmidomycin

scientific article

Arsenate and phosphate as nucleophiles at the transition states of human purine nucleoside phosphorylase

scientific article published on 10 March 2011

Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases

scientific article published on 6 February 2008

Commentary: Ohm's law as an analogy for enzyme kinetics

scientific article published on 20 February 2015

Cysteine is the general base that serves in catalysis by isocitrate lyase and in mechanism-based inhibition by 3-nitropropionate

scientific article published on 24 December 2013

DXP reductoisomerase: reaction of the substrate in pieces reveals a catalytic role for the nonreacting phosphodianion group

scientific article published on 20 March 2013

Dehydroalanine-based inhibition of a peptide epimerase from spider venom

scientific article

Femtosecond dynamics coupled to chemical barrier crossing in a Born-Oppenheimer enzyme

scientific article published on 7 November 2011

Highly precise measurement of kinetic isotope effects using 1H-detected 2D [13C,1H]-HSQC NMR spectroscopy

scientific article published in 2012

Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening

scientific article

Immucillins in custom catalytic-site cavities

scientific article published on 19 August 2008

Inverse Solvent Isotope Effects in Enzyme-Catalyzed Reactions

scientific article published on 21 April 2020

Mechanism and inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase

scientific article published on 19 June 2014

Mechanism-based inactivator of isocitrate lyases 1 and 2 from Mycobacterium tuberculosis.

scientific article published on 5 July 2017

Neighboring Group Participation in the Transition State of Human Purine Nucleoside Phosphorylase †

scientific article

New Electrophiles and Strategies for Mechanism-Based and Targeted Covalent Inhibitor Design

scientific article published on 24 April 2019

Phosphate activation in the ground state of purine nucleoside phosphorylase.

scientific article

Plasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal model

scientific article (publication date: 2011)

Pre-steady-state kinetic analysis of 1-deoxy-D-xylulose-5-phosphate reductoisomerase from Mycobacterium tuberculosis reveals partially rate-limiting product release by parallel pathways.

scientific article published on 21 June 2012

Ribocation transition state capture and rebound in human purine nucleoside phosphorylase

scientific article published in September 2009

The Nitro Group as a Masked Electrophile in Covalent Enzyme Inhibition

scientific article published on 23 May 2018

The role of phosphate in a multistep enzymatic reaction: reactions of the substrate and intermediate in pieces

scientific article published on 10 February 2015

Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase

scientific article published on February 2009

Transition state analogue discrimination by related purine nucleoside phosphorylases

scientific article

Transition-state interactions revealed in purine nucleoside phosphorylase by binding isotope effects

scientific article published on 30 January 2008

l -Enantiomers of Transition State Analogue Inhibitors Bound to Human Purine Nucleoside Phosphorylase

scientific article

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