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List of works by Sophie Lestavel

A High Concentration of Melatonin Inhibits In Vitro LDL Peroxidation But Not Oxidized LDL Toxicity Toward Cultured Endothelial Cells

article

A novel splice site mutation of the LDL receptor gene in a Tunisian hypercholesterolemic family.

scientific article published on 4 March 2008

Activation of intestinal peroxisome proliferator-activated receptor-α increases high-density lipoprotein production

scientific article published on 26 July 2012

Apolipoprotein AII enrichment of HDL enhances their affinity for class B type I scavenger receptor but inhibits specific cholesteryl ester uptake

scientific article

Beneficial effects of exercise in a transgenic mouse model of Alzheimer's disease-like Tau pathology.

scientific article published on 4 May 2011

Bile Acid Alterations Are Associated With Insulin Resistance, but Not With NASH, in Obese Subjects

scientific article

CYS127S (FH-Kairouan) and D245N (FH-Tozeur) mutations in the LDL receptor gene in Tunisian families with familial hypercholesterolaemia

scientific article

Cholesterol homeostasis is controlled by peroxisome proliferator-activated receptor alpha in human macrophages

Daily melatonin supplementation in mice increases atherosclerosis in proximal aorta

scientific article

Defective VLDL metabolism and severe atherosclerosis in mice expressing human apolipoprotein E isoforms but lacking the LDL receptor

scientific article published in August 2004

Early-glycation of apolipoprotein E: effect on its binding to LDL receptor, scavenger receptor A and heparan sulfates.

scientific article

Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity

scientific article

Farnesoid X receptor inhibits glucagon-like peptide-1 production by enteroendocrine L cells

scientific article

Ffar2 expression regulates leukaemic cell growth in vivo.

scientific article published on 5 September 2017

Food-Derived Hemorphins Cross Intestinal and Blood-Brain Barriers In Vitro

scientific article

HDL3 binds to glycosylphosphatidylinositol-anchored proteins to activate signalling pathways

scientific article published on 01 August 1997

High-density-lipoprotein subfraction 3 interaction with glycosylphosphatidylinositol-anchored proteins.

scientific article published on December 1997

Human free apolipoprotein A-I and artificial pre-beta-high-density lipoprotein inhibit eNOS activity and NO release.

scientific article published in July 2004

Immunological and functional properties of in vitro oxidized low density lipoprotein

scientific article published on 01 May 1995

Influence of Roux-en-Y gastric bypass on plasma bile acid profiles: a comparative study between rats, pigs and humans.

scientific article published on 22 March 2016

Intestinal bile acid receptors are key regulators of glucose homeostasis

scientific article published on 16 November 2016

Intestine-specific regulation of PPARalpha gene transcription by liver X receptors

scientific article published on 19 June 2008

Lipid free apolipoprotein E binds to the class B Type I scavenger receptor I (SR-BI) and enhances cholesteryl ester uptake from lipoproteins

scientific article (publication date: 27 September 2002)

Liver X Receptor Regulates Triglyceride Absorption Through Intestinal Down-regulation of Scavenger Receptor Class B, Type 1.

scientific article published on 18 November 2015

Liver X receptor activation controls intracellular cholesterol trafficking and esterification in human macrophages

scientific article

Liver X receptor activation induces the uptake of cholesteryl esters from high density lipoproteins in primary human macrophages

scientific article

Modified low density lipoproteins activate human macrophages to secrete immunoreactive endothelin

scientific article published on 01 November 1991

Mutation screening of the LDLR gene and ApoB gene in patients with a phenotype of familial hypercholesterolemia and normal values in a functional LDL receptor/apolipoprotein B assay

article

Niemann-Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine

scientific article published on 5 January 2006

P-glycoprotein and cytochrome P450 3A4 involvement in risperidone transport using an in vitro Caco-2/TC7 model and an in vivo model

scientific article

PPAR (peroxisome proliferator-activated receptors) et paroi vasculaire : implications dans l'athérosclérose

article published in 2001

PPARs regulate genes involved in cholesterol homeostasis in human monocyte/macrophages

article

PPARβ/δ activation induces enteroendocrine L cell GLP-1 production

scientific article

Peroxisome proliferator-activated receptor alpha controls cellular cholesterol trafficking in macrophages

scientific article

Peroxisome proliferator-activated receptor alpha reduces cholesterol esterification in macrophages

scientific article

Reconstitution of hepatitis C virus envelope glycoproteins into liposomes as a surrogate model to study virus attachment

scientific article published on 5 April 2002

Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.

scientific article

Retrograde cholesterol transport in the human Caco-2/TC7 cell line: a model to study trans-intestinal cholesterol excretion in atherogenic and diabetic dyslipidemia

scientific article published on 28 October 2016

Rexinoid bexarotene modulates triglyceride but not cholesterol metabolism via gene-specific permissivity of the RXR/LXR heterodimer in the liver

scientific article

Role of Serum Amyloid A During Metabolism of Acute-Phase HDL by Macrophages

scientific article published on 01 March 2000

Roux-en-Y gastric bypass increases systemic but not portal bile acid concentrations by decreasing hepatic bile acid uptake in minipigs

SR-BI does not require raft/caveola localisation for cholesteryl ester selective uptake in the human adrenal cell line NCI-H295R.

scientific article published on February 2003

Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction.

scientific article published on 4 April 2017

The RXR Agonist Bexarotene Improves Cholesterol Homeostasis and Inhibits Atherosclerosis Progression in a Mouse Model of Mixed Dyslipidemia

article

The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis

Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance

scientific article published on 17 April 2017

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