List of works - Elisabetta Cerbai

5-HT2 receptors enable cardiac differentiation of mouse embryonic stem cells

ATP Modulates Cell Proliferation and Elicits Two Different Electrophysiological Responses in Human Mesenchymal Stem Cells

article

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

scientific article published on 18 August 2010

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

scientific article

Altered Ca and Na Homeostasis in Human Hypertrophic Cardiomyopathy: Implications for Arrhythmogenesis

scientific article published on 16 October 2018

Angiotensin AT2 receptor: the younger sibling attracts attention

scientific article published in April 2004

Angiotensin-II Drives Human Satellite Cells Toward Hypertrophy and Myofibroblast Trans-Differentiation by Two Independent Pathways

scientific article published on 03 October 2019

Antiarrhythmic properties of naloxone: an electrophysiological study on sheep cardiac Purkinje fibers

scientific article published on 01 March 1989

Arterial hypertension and atrial fibrillation: standard and advanced echocardiography from diagnosis to prognostication.

scientific article published on 14 December 2017

Atrial natriuretic peptide modulates the hyperpolarization-activated current (If) in human atrial myocytes

scientific article

Beating to time: calcium clocks, voltage clocks, and cardiac pacemaker activity

scientific article published on 16 January 2009

Beta 1- and beta 2-adrenoceptors in sheep cardiac ventricular muscle

scientific article published in July 1992

Beta-adrenoceptor subtypes in young and old rat ventricular myocytes: a combined patch-clamp and binding study.

scientific article published on September 1995

Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes

scientific article published on November 2016

Calcium-Dependent Electrophysiological Alterations in Hypertrophied Rat Cardiomyocytes

scientific article published on 01 December 1996

Cardiac and electrophysiological effects of primary and refined extracts from Leonurus cardiaca L. (Ph.Eur.).

scientific article published on 16 November 2009

Cardiac effects of 3-iodothyronamine: a new aminergic system modulating cardiac function

scientific article

Cardiac electrophysiologic effects of a new calcium antagonist, lacidipine

scientific article published on April 1, 1990

Cardiac electrophysiological effects of a new dihydropyridine calcium antagonist (BBR 2160).

scientific article published in January 1991

Cellular electrophysiological aspects of myocardial protection

scientific article published on 01 March 1995

Characteristics of L-type calcium channel blockade by lacidipine in guinea-pig ventricular myocytes.

scientific article published on February 1997

Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation

scientific article published on 22 August 2007

Characterization of the hyperpolarization-activated current, I(f), in ventricular myocytes isolated from hypertensive rats

scientific article published on 01 December 1994

Chronic atrial fibrillation alters the functional properties of If in the human atrium

scientific article

Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy

scientific article published on 9 October 2017

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure

scientific article

Defining the diagnostic effectiveness of genes for inclusion in panels: the experience of two decades of genetic testing for hypertrophic cardiomyopathy at a single center

scientific article published on 06 June 2018

Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current.

scientific article published in February 2005

Design, synthesis, and preliminary biological evaluation of new isoform-selective f-current blockers

scientific article published on September 2010

Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction

scientific article published on 01 April 2019

Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach

scientific article published on 25 January 2007

Do amniotic fluid-derived stem cells differentiate into neurons in vitro?

scientific article published in March 2008

Does recombinant human interleukin-11 exert direct electrophysiologic effects on single human atrial myocytes?

scientific article published in March 2002

EC18 as a Tool To Understand the Role of HCN4 Channels in Mediating Hyperpolarization-Activated Current in Tissues

scientific article published on 06 February 2019

Editorial: The Role of Calcium Handling in Heart Failure and Heart Failure Associated Arrhythmias

scientific article published on 22 January 2019

Effect of 5-HT4 receptor stimulation on the pacemaker current If in human isolated atrial myocytes

scientific article published on 01 December 1998

Effect of BBR 2160 on ICa recorded from guinea-pig isolated myocytes.

scientific article published in September 1990

Effects of chronic atrial fibrillation on active and passive force generation in human atrial myofibrils.

scientific article published on 13 May 2010

Electrophysiologic changes in heart failure: focus on pacemaker channels

scientific article published on February 2009

Electrophysiologic effects of lercanidipine on repolarizing potassium currents

scientific article

Electrophysiological Basis for the Enhanced Cardiac Arrhythmogenic Effect of Isoprenaline in Aged Spontaneously Hypertensive Rats

scientific article published on 01 July 1994

Electrophysiological characterization of cardiac β2-adrenoceptors in sheep Purkinje fibers

scientific article published on 01 August 1990

Electrophysiological characterization of isolated human atrial myocytes exposed to tegaserod.

scientific article published on 30 December 2009

Electrophysiological effects mediated by the stimulation of cardiac beta 2-adrenoceptors with tulobuterol.

scientific article published in January 1987

Electrophysiological effects of ivabradine in dog and human cardiac preparations: Potential antiarrhythmic actions

scientific article published on 02 August 2011

Enhanced ROS production by NADPH oxidase is correlated to changes in antioxidant enzyme activity in human heart failure

scientific article published on 3 November 2009

Expression of the hyperpolarization-activated current, I(f), in cultured adult rat ventricular cardiomyocytes and its modulation by hypertrophic factors

scientific article published on 5 February 2008

Fetal bovine serum enables cardiac differentiation of human embryonic stem cells

scientific article published on 25 April 2007

From in vivo plasma composition to in vitro cardiac electrophysiology and in silico virtual heart: the extracellular calcium enigma

scientific article published in June 2009

Frontiers in Cardiovascular Biology: a forum for exploratory basic science and translational research from the ESC Council for Basic Cardiovascular Sciences

scientific article published on 10 June 2016

Functional coupling of angiotensin II type 1 receptor with insulin resistance of energy substrate uptakes in immortalized cardiomyocytes (HL-1 cells).

scientific article published on 5 November 2007

Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes

scientific article

Functional remodeling in post-myocardial infarcted rats: focus on beta-adrenoceptor subtypes.

scientific article published on 19 January 2006

Growth factor-induced mobilization of cardiac progenitor cells reduces the risk of arrhythmias, in a rat model of chronic myocardial infarction.

scientific article

Heart rate reduction with ivabradine prevents the global phenotype of left ventricular remodeling

article

Histamine and abnormal automaticity in barium- and strophanthidin-treated sheep Purkinje fibers.

scientific article published on August 1990

Holt–Oram Syndrome and Atrial Fibrillation

scientific article published on 01 June 2008

Human amniotic fluid stem cell differentiation along smooth muscle lineage

Hyperpolarization-activated cyclic-nucleotide-gated channels: pathophysiological, developmental, and pharmacological insights into their function in cellular excitability

scientific article published on 03 July 2018

I(f) in non-pacemaker cells: role and pharmacological implications.

scientific article

Identifying needs and opportunities for advancing translational research in cardiovascular disease

article published in 2009

Impact of detubulation on force and kinetics of cardiac muscle contraction.

scientific article

Influence of postnatal-development on If occurrence and properties in neonatal rat ventricular myocytes

article

Ionic basis of action potential prolongation of hypertrophied cardiac myocytes isolated from hypertensive rats of different ages

scientific article published on 01 August 1994

Isolated cardiac cells for electropharmacological studies

scientific article

Isolation and functional characterization of human ventricular cardiomyocytes from fresh surgical samples

scientific article published on 21 April 2014

Italy's stem-cell challenge gaining momentum

scientific article published in Nature

Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy

scientific article published on 27 December 2012

Late sodium current inhibitors to treat exercise-induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium.

scientific article

Lercanidipine and T-type calcium current

scientific article published on 01 June 2018

Letter to the Editor

scientific article published on 14 April 2019

Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair

scientific article published on 17 October 2017

Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh

scientific article published in May 2000

Long-term treatment of spontaneously hypertensive rats with losartan and electrophysiological remodeling of cardiac myocytes

scientific article published on 01 January 2000

Long-term treatment with ivabradine in post-myocardial infarcted rats counteracts f-channel overexpression

scientific article

Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats

scientific article published on 22 June 2009

Mathematical modelling of the action potential of human embryonic stem cell derived cardiomyocytes.

scientific article published on 28 August 2012

Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy

scientific article published on 15 September 2015

Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing.

scientific article

Modulation of cardiac ionic homeostasis by 3-iodothyronamine.

scientific article published on 27 February 2009

Modulation of the pacemaker current If by β-adrenoceptor subtypes in ventricular myocytes isolated from hypertensive and normotensive rats

scientific article published on 01 April 1999

Molecular and functional development of cardiomyocytes differentiated from human embryonic stem cells

article

Molecular and functional evidence of HCN4 and caveolin-3 interaction during cardiomyocyte differentiation from human embryonic stem cells

scientific article published on 27 February 2013

Molecular basis of funny current (If) in normal and failing human heart.

scientific article published on 11 May 2008

Myocardial 123I-metaiodobenzylguanidine imaging in hypertension and left ventricular hypertrophy

scientific article published on 10 August 2017

NADPH oxidase-dependent redox signaling in human heart failure: Relationship between the left and right ventricle

scientific article published in April 2007

Nitric oxide/reactive oxygen species generation and nitroso/redox imbalance in heart failure: from molecular mechanisms to therapeutic implications.

scientific article published on 29 September 2010

Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors.

scientific article

Novel blockers of hyperpolarization-activated current with isoform selectivity in recombinant cells and native tissue

scientific article

Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.

scientific article published on 20 December 2015

Oleuropein aglycon prevents cytotoxic amyloid aggregation of human amylin.

scientific article

Optical Investigation of Action Potential and Calcium Handling Maturation of hiPSC-Cardiomyocytes on Biomimetic Substrates

scientific article published on 03 August 2019

Optogenetics design of mechanistically-based stimulation patterns for cardiac defibrillation.

scientific article

P633Ranolazine reduces arrhythmogeneicity in transgenic mouse models of hypertrophic cardiomyopathy

Pathogenesis of Hypertrophic Cardiomyopathy is Mutation Rather Than Disease Specific: A Comparison of the Cardiac Troponin T E163R and R92Q Mouse Models.

scientific article published on 22 July 2017

Pharmacological modulation of the hyperpolarization-activated current (I f) in human atrial myocytes: focus on G protein-coupled receptors

scientific article published in March 2005

Prenatal Exposure to Carbon Monoxide Affects Postnatal Cellular Electrophysiological Maturation of the Rat Heart

scientific article published on 12 January 2004

Prenatal exposure to carbon monoxide delays postnatal cardiac maturation

scientific article published on 19 July 2010

Probing cell activity in random access modality

Probing the spatiotemporal relationship between intracellular Ca2+release and action potential propagation in cardiomyocytes by ultrafast multi-photon random access microscopy

Prolonged propionyl-L-carnitine pre-treatment of rabbit: biochemical, hemodynamic and electrophysiological effects on myocardium.

scientific article published in March 1992

Protective effect of darodipine, a calcium antagonist, on rat cardiomyocytes against oxygen radical-mediated injury

scientific article published in December 1997

Quantitative assessment of passive electrical properties of the cardiac T-tubular system by FRAP microscopy.

scientific article

R4496C RyR2 mutation impairs atrial and ventricular contractility

scientific article published on 14 December 2015

Ranolazine Prevents Phenotype Development in a Mouse Model of Hypertrophic Cardiomyopathy.

scientific article published in March 2017

Real-time optical manipulation of cardiac conduction in intact hearts

scientific article published on 07 August 2018

Regulation of intracellular Na(+) in health and disease: pathophysiological mechanisms and implications for treatment

scientific article

Reply to Entcheva: The impact of T-tubules on action potential propagation in cardiac tissue.

scientific article

Resistant hypertension: an overview.

scientific article published on 5 September 2017

Response to Letter Regarding Article, “Late Sodium Current Inhibition Reverses Electromechanical Dysfunction in Human Hypertrophic Cardiomyopathy”

scientific article published on 01 September 2013

Restoration of cardiomyocyte functional properties by angiotensin II receptor blockade in diabetic rats

scientific article

Role of potassium currents in cardiac arrhythmias

scientific article published on 24 July 2008

Selective Blockade of HCN1/HCN2 Channels as a Potential Pharmacological Strategy Against Pain

scientific article published on 08 November 2018

Selective HCN1 block as a strategy to control oxaliplatin-induced neuropathy.

scientific article published on 12 January 2018

Selective Pharmacological Inhibition of the Pacemaker Channel Isoforms (HCN1-4) as New Possible Therapeutical Targets ⬇️

scientific article published on January 1, 2011

Selectivity of different calcium antagonists on T- and L-type calcium currents in guinea-pig ventricular myocytes

scientific article published in December 2002

Sex-related differences in chronic heart failure

scientific article published in March 2018

Simultaneous recording of t-tubular electrical activity and Ca2+-release in heart failure

Survey of barium in Italian drinking water supplies

article

Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes.

scientific article published in December 2018

T-Tubular Electrical Defects Contribute to Blunted β-Adrenergic Response in Heart Failure.

scientific article

Temperature modulates calcium homeostasis and ventricular arrhythmias in myocardial preparations

scientific article published on 01 March 1994

Tension generation and relaxation in single myofibrils from human atrial and ventricular myocardium

scientific article published on 23 November 2006

The Hyperpolarization-Activated Cyclic Nucleotide-Gated Channels: from Biophysics to Pharmacology of a Unique Family of Ion Channels.

scientific article

The Properties of the Pacemaker Current IFin Human Ventricular Myocytes are Modulated by Cardiac Disease

scientific article published on 01 March 2001

The alpha subunit of the GTP binding protein activates muscarinic potassium channels of the atrium

scientific article

The effect of losartan treatment on the response of diabetic cardiomyocytes to ATP depletion

scientific article published on 13 November 2010

The effects of gender on electrical therapies for the heart: physiology, epidemiology, and access to therapies: A report from the XII Congress of the Italian Association on Arrhythmology and Cardiostimulation (AIAC).

scientific article

The hyperpolarization-activated cyclic nucleotide-gated 4 channel as a potential anti-seizure drug target

scientific article published on 04 May 2020

The importance of integrated left atrial evaluation: From hypertension to heart failure with preserved ejection fraction.

scientific article published on 28 December 2017

The pacemaker current I(f) in single human atrial myocytes and the effect of beta-adrenoceptor and A1-adenosine receptor stimulation.

scientific article

The role of temperature on the development of oscillatory afterpotentials and triggered activity

article

The transverse-axial tubular system of cardiomyocytes

scientific article published on 12 July 2013

Treatment with irbesartan counteracts the functional remodeling of ventricular myocytes from hypertensive rats

scientific article published in May 2003

Updates on HCN Channels in the Heart: Function, Dysfunction and Pharmacology

scientific article published on 31 May 2015

n-3 polyunsaturated fatty acids supplementation decreases asymmetric dimethyl arginine and arachidonate accumulation in aging spontaneously hypertensive rats

scientific article published on 14 September 2004

List of works by Elisabetta Cerbai

5-HT2 receptors enable cardiac differentiation of mouse embryonic stem cells

ATP Modulates Cell Proliferation and Elicits Two Different Electrophysiological Responses in Human Mesenchymal Stem Cells

Acetaminophen, via its reactive metabolite N-acetyl-p-benzo-quinoneimine and transient receptor potential ankyrin-1 stimulation, causes neurogenic inflammation in the airways and other tissues in rodents

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

Altered Ca and Na Homeostasis in Human Hypertrophic Cardiomyopathy: Implications for Arrhythmogenesis

Angiotensin AT2 receptor: the younger sibling attracts attention

Angiotensin-II Drives Human Satellite Cells Toward Hypertrophy and Myofibroblast Trans-Differentiation by Two Independent Pathways

Antiarrhythmic properties of naloxone: an electrophysiological study on sheep cardiac Purkinje fibers

Arterial hypertension and atrial fibrillation: standard and advanced echocardiography from diagnosis to prognostication.

Atrial natriuretic peptide modulates the hyperpolarization-activated current (If) in human atrial myocytes

Beating to time: calcium clocks, voltage clocks, and cardiac pacemaker activity

Beta 1- and beta 2-adrenoceptors in sheep cardiac ventricular muscle

Beta-adrenoceptor subtypes in young and old rat ventricular myocytes: a combined patch-clamp and binding study.

Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes

Calcium-Dependent Electrophysiological Alterations in Hypertrophied Rat Cardiomyocytes

Cardiac and electrophysiological effects of primary and refined extracts from Leonurus cardiaca L. (Ph.Eur.).

Cardiac effects of 3-iodothyronamine: a new aminergic system modulating cardiac function

Cardiac electrophysiologic effects of a new calcium antagonist, lacidipine

Cardiac electrophysiological effects of a new dihydropyridine calcium antagonist (BBR 2160).

Cellular electrophysiological aspects of myocardial protection

Characteristics of L-type calcium channel blockade by lacidipine in guinea-pig ventricular myocytes.

Characterization of a novel SCN5A mutation associated with Brugada syndrome reveals involvement of DIIIS4-S5 linker in slow inactivation

Characterization of the hyperpolarization-activated current, I(f), in ventricular myocytes isolated from hypertensive rats

Chronic atrial fibrillation alters the functional properties of If in the human atrium

Content of mitochondrial calcium uniporter (MCU) in cardiomyocytes is regulated by microRNA-1 in physiologic and pathologic hypertrophy

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure

Defining the diagnostic effectiveness of genes for inclusion in panels: the experience of two decades of genetic testing for hypertrophic cardiomyopathy at a single center

Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current.

Design, synthesis, and preliminary biological evaluation of new isoform-selective f-current blockers

Development of Light-Responsive Liquid Crystalline Elastomers to Assist Cardiac Contraction

Developmental changes in cardiomyocytes differentiated from human embryonic stem cells: a molecular and electrophysiological approach

Do amniotic fluid-derived stem cells differentiate into neurons in vitro?

Does recombinant human interleukin-11 exert direct electrophysiologic effects on single human atrial myocytes?

EC18 as a Tool To Understand the Role of HCN4 Channels in Mediating Hyperpolarization-Activated Current in Tissues

Editorial: The Role of Calcium Handling in Heart Failure and Heart Failure Associated Arrhythmias

Effect of 5-HT4 receptor stimulation on the pacemaker current If in human isolated atrial myocytes

Effect of BBR 2160 on ICa recorded from guinea-pig isolated myocytes.

Effects of chronic atrial fibrillation on active and passive force generation in human atrial myofibrils.

Electrophysiologic changes in heart failure: focus on pacemaker channels

Electrophysiologic effects of lercanidipine on repolarizing potassium currents

Electrophysiological Basis for the Enhanced Cardiac Arrhythmogenic Effect of Isoprenaline in Aged Spontaneously Hypertensive Rats

Electrophysiological characterization of cardiac β2-adrenoceptors in sheep Purkinje fibers

Electrophysiological characterization of isolated human atrial myocytes exposed to tegaserod.

Electrophysiological effects mediated by the stimulation of cardiac beta 2-adrenoceptors with tulobuterol.

Electrophysiological effects of ivabradine in dog and human cardiac preparations: Potential antiarrhythmic actions

Enhanced ROS production by NADPH oxidase is correlated to changes in antioxidant enzyme activity in human heart failure

Expression of the hyperpolarization-activated current, I(f), in cultured adult rat ventricular cardiomyocytes and its modulation by hypertrophic factors

Fetal bovine serum enables cardiac differentiation of human embryonic stem cells

From in vivo plasma composition to in vitro cardiac electrophysiology and in silico virtual heart: the extracellular calcium enigma

Frontiers in Cardiovascular Biology: a forum for exploratory basic science and translational research from the ESC Council for Basic Cardiovascular Sciences

Functional coupling of angiotensin II type 1 receptor with insulin resistance of energy substrate uptakes in immortalized cardiomyocytes (HL-1 cells).

Functional expression of the hyperpolarization-activated, non-selective cation current I(f) in immortalized HL-1 cardiomyocytes

Functional remodeling in post-myocardial infarcted rats: focus on beta-adrenoceptor subtypes.

Growth factor-induced mobilization of cardiac progenitor cells reduces the risk of arrhythmias, in a rat model of chronic myocardial infarction.

Heart rate reduction with ivabradine prevents the global phenotype of left ventricular remodeling

Histamine and abnormal automaticity in barium- and strophanthidin-treated sheep Purkinje fibers.

Holt–Oram Syndrome and Atrial Fibrillation

Human amniotic fluid stem cell differentiation along smooth muscle lineage

Hyperpolarization-activated cyclic-nucleotide-gated channels: pathophysiological, developmental, and pharmacological insights into their function in cellular excitability

I(f) in non-pacemaker cells: role and pharmacological implications.

Identifying needs and opportunities for advancing translational research in cardiovascular disease

Impact of detubulation on force and kinetics of cardiac muscle contraction.

Influence of postnatal-development on If occurrence and properties in neonatal rat ventricular myocytes

Ionic basis of action potential prolongation of hypertrophied cardiac myocytes isolated from hypertensive rats of different ages

Isolated cardiac cells for electropharmacological studies

Isolation and functional characterization of human ventricular cardiomyocytes from fresh surgical samples

Italy's stem-cell challenge gaining momentum

Late sodium current inhibition reverses electromechanical dysfunction in human hypertrophic cardiomyopathy

Late sodium current inhibitors to treat exercise-induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium.

Lercanidipine and T-type calcium current

Letter to the Editor

Liquid Crystalline Networks toward Regenerative Medicine and Tissue Repair

Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh

Long-term treatment of spontaneously hypertensive rats with losartan and electrophysiological remodeling of cardiac myocytes

Long-term treatment with ivabradine in post-myocardial infarcted rats counteracts f-channel overexpression

Losartan counteracts the hyper-reactivity to angiotensin II and ROCK1 over-activation in aortas isolated from streptozotocin-injected diabetic rats

Mathematical modelling of the action potential of human embryonic stem cell derived cardiomyocytes.

Mechanisms of pro-arrhythmic abnormalities in ventricular repolarisation and anti-arrhythmic therapies in human hypertrophic cardiomyopathy

Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing.