List of works - Dana S Hutchinson

AMP-activated protein kinase activation by adrenoceptors in L6 skeletal muscle cells: mediation by alpha1-adrenoceptors causing glucose uptake

scientific article published in March 2006

Adrenoceptor regulation of the mechanistic target of rapamycin in muscle and adipose tissue

scientific article published on 07 April 2019

Adrenoceptors in white, brown, and brite adipocytes

scientific article published on 07 April 2019

Adrenoceptors promote glucose uptake into adipocytes and muscle by an insulin-independent signaling pathway involving mechanistic target of rapamycin complex 2.

scientific article published on 23 December 2016

Agonist effects of zinterol at the mouse and human beta(3)-adrenoceptor

scientific article published on 7 April 2006

Alpha1- and beta1-adrenoceptor signaling fully compensates for beta3-adrenoceptor deficiency in brown adipocyte norepinephrine-stimulated glucose uptake

scientific article published on 21 January 2005

Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?

scientific article

Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus

scientific article published on 31 May 2017

BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β2-adrenoceptors without causing classical receptor desensitization

scientific article published on 20 March 2019

Beta 3-adrenoceptors: their role and regulation in the gastrointestinal tract

article

Beta(2)-Adrenergic activation increases glycogen synthesis in L6 skeletal muscle cells through a signalling pathway independent of cyclic AMP.

scientific article published on 22 November 2006

Beta-adrenoceptors, but not alpha-adrenoceptors, stimulate AMP-activated protein kinase in brown adipocytes independently of uncoupling protein-1.

scientific article

Beta2- and beta3-adrenoceptors activate glucose uptake in chick astrocytes by distinct mechanisms: a mechanism for memory enhancement?

scientific article published on 6 August 2007

CIS is a potent checkpoint in NK cell-mediated tumor immunity

scientific article

Could burning fat start with a brite spark? Pharmacological and nutritional ways to promote thermogenesis

scientific article published on 22 July 2015

DNAM-1 expression marks an alternative program of NK cell maturation.

scientific article published on 26 March 2015

Diphenylene iodonium stimulates glucose uptake in skeletal muscle cells through mitochondrial complex I inhibition and activation of AMP-activated protein kinase

scientific article

Effects of hypoxia-ischemia and inotropes on expression of cardiac adrenoceptors in the preterm fetal sheep

scientific article published on 23 August 2018

Energy metabolism and memory processing: role of glucose transport and glycogen in responses to adrenoceptor activation in the chicken

scientific article published on 06 March 2008

Evidence for pleiotropic signaling at the mouse beta3-adrenoceptor revealed by SR59230A [3-(2-Ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2S-2-propanol oxalate].

scientific article published on December 2004

Factors influencing biased agonism in recombinant cells expressing the human α1A -adrenoceptor

scientific article published on 25 April 2017

Functional domains of the mouse beta(3)-adrenoceptor associated with differential G-protein coupling.

scientific article published on November 2007

Functional domains of the mouse beta3-adrenoceptor associated with differential G protein coupling

scientific article

G protein coupled receptor 18: A potential role for endocannabinoid signaling in metabolic dysfunction.

scientific article published on 03 September 2015

Glucose uptake in brown fat cells is dependent on mTOR complex 2-promoted GLUT1 translocation

scientific article

INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells.

scientific article published in April 2018

Importance of adrenergic receptors in prenatally induced cognitive impairment in the domestic chick.

scientific article

Improving type 2 diabetes through a distinct adrenergic signaling pathway involving mTORC2 that mediates glucose uptake in skeletal muscle.

scientific article

Interaction with Caveolin-1 Modulates G Protein Coupling of Mouse β3-Adrenoceptor ⬇️

scientific article published on April 25, 2012

Ligand-directed signaling at the beta3-adrenoceptor produced by 3-(2-Ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2S-2-propanol oxalate (SR59230A) relative to receptor agonists

scientific article published on 23 August 2007

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.

scientific article

Memory processing in the avian hippocampus involves interactions between beta-adrenoceptors, glutamate receptors, and metabolism

scientific article published on 6 February 2008

Mirabegron: potential off target effects and uses beyond the bladder.

scientific article

Noradrenaline release in the locus coeruleus modulates memory formation and consolidation; roles for α- and β-adrenergic receptors.

scientific article published on 13 August 2010

Orthosteric binding of ρ-Da1a, a natural peptide of snake venom interacting selectively with the α1A-adrenoceptor

scientific article

Peripheral modulation of the endocannabinoid system in metabolic disease

scientific article published on 10 January 2018

Quantification of functional selectivity at the human α(1A)-adrenoceptor.

scientific article published on 26 October 2010

Rapid turnover of glycogen in memory formation

scientific article

Response to Comment on Sato et al. Improving type 2 diabetes through a distinct adrenergic signaling pathway involving mTORC2 that mediates glucose uptake in skeletal muscle. Diabetes 2014;63:4115-4129.

scientific article published in December 2014

Role of beta-adrenoceptors in memory consolidation: beta3-adrenoceptors act on glucose uptake and beta2-adrenoceptors on glycogenolysis

scientific article published on 28 November 2007

Role of β-adrenoceptors in glucose uptake in astrocytes using β-adrenoceptor knockout mice.

scientific article

Rosiglitazone and a β3-Adrenoceptor Agonist Are Both Required for Functional Browning of White Adipocytes in Culture.

scientific article published on 30 May 2018

Shikonin increases glucose uptake in skeletal muscle cells and improves plasma glucose levels in diabetic Goto-Kakizaki rats

scientific article

Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor.

scientific article published on 31 May 2016

Stereoselectivity for interactions of agonists and antagonists at mouse, rat and human beta3-adrenoceptors

scientific article published in January 2004

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.

scientific article published on 9 January 2016

The Janus faces of adrenoceptors: factors controlling the coupling of adrenoceptors to multiple signal transduction pathways.

scientific article

The M3-muscarinic acetylcholine receptor stimulates glucose uptake in L6 skeletal muscle cells by a CaMKK-AMPK-dependent mechanism

scientific article published on 4 March 2010

The PPARγ agonist rosiglitazone promotes the induction of brite adipocytes, increasing β-adrenoceptor-mediated mitochondrial function and glucose uptake.

scientific article

The actions of relaxin family peptides on signal transduction pathways activated by the relaxin family peptide receptor RXFP4.

scientific article published on 26 November 2016

The beta3-adrenoceptor agonist 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]-phenyl]-benzenesulfonamide (L755507) and antagonist (S)-N-[4-[2-[[3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]-e

scientific article published on 6 August 2008

The metabolic effects of mirabegron are mediated primarily by β3 -adrenoceptors

scientific article published on 01 October 2020

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

scientific article published on 27 August 2019

beta(3)-adrenoceptor regulation and relaxation responses in mouse ileum

scientific article

α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes.

scientific article published on 23 November 2017

α₂-Adrenoceptors activate noradrenaline-mediated glycogen turnover in chick astrocytes.

scientific article

β1-Adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β3-adrenergic receptor-knockout mice via nonshivering thermogenesis

article

β2-Adrenoceptor-mediated regulation of glucose uptake in skeletal muscle--ligand-directed signalling or a reflection of system complexity?

scientific article published on 9 May 2013

β2‐Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C‐terminal tail ⬇️

scientific article published on March 1, 2012

List of works by Dana S Hutchinson

AMP-activated protein kinase activation by adrenoceptors in L6 skeletal muscle cells: mediation by alpha1-adrenoceptors causing glucose uptake

Adrenoceptor regulation of the mechanistic target of rapamycin in muscle and adipose tissue

Adrenoceptors in white, brown, and brite adipocytes

Adrenoceptors promote glucose uptake into adipocytes and muscle by an insulin-independent signaling pathway involving mechanistic target of rapamycin complex 2.

Agonist effects of zinterol at the mouse and human beta(3)-adrenoceptor

Alpha1- and beta1-adrenoceptor signaling fully compensates for beta3-adrenoceptor deficiency in brown adipocyte norepinephrine-stimulated glucose uptake

Altered regulation of the PINK1 locus: a link between type 2 diabetes and neurodegeneration?

Assessing the anthelmintic activity of pyrazole-5-carboxamide derivatives against Haemonchus contortus

BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via β2-adrenoceptors without causing classical receptor desensitization

Beta 3-adrenoceptors: their role and regulation in the gastrointestinal tract

Beta(2)-Adrenergic activation increases glycogen synthesis in L6 skeletal muscle cells through a signalling pathway independent of cyclic AMP.

Beta-adrenoceptors, but not alpha-adrenoceptors, stimulate AMP-activated protein kinase in brown adipocytes independently of uncoupling protein-1.

Beta2- and beta3-adrenoceptors activate glucose uptake in chick astrocytes by distinct mechanisms: a mechanism for memory enhancement?

CIS is a potent checkpoint in NK cell-mediated tumor immunity

Could burning fat start with a brite spark? Pharmacological and nutritional ways to promote thermogenesis

DNAM-1 expression marks an alternative program of NK cell maturation.

Diphenylene iodonium stimulates glucose uptake in skeletal muscle cells through mitochondrial complex I inhibition and activation of AMP-activated protein kinase

Effects of hypoxia-ischemia and inotropes on expression of cardiac adrenoceptors in the preterm fetal sheep

Energy metabolism and memory processing: role of glucose transport and glycogen in responses to adrenoceptor activation in the chicken

Evidence for pleiotropic signaling at the mouse beta3-adrenoceptor revealed by SR59230A [3-(2-Ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2S-2-propanol oxalate].

Factors influencing biased agonism in recombinant cells expressing the human α1A -adrenoceptor

Functional domains of the mouse beta(3)-adrenoceptor associated with differential G-protein coupling.

Functional domains of the mouse beta3-adrenoceptor associated with differential G protein coupling

G protein coupled receptor 18: A potential role for endocannabinoid signaling in metabolic dysfunction.

Glucose uptake in brown fat cells is dependent on mTOR complex 2-promoted GLUT1 translocation

INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells.

Importance of adrenergic receptors in prenatally induced cognitive impairment in the domestic chick.

Improving type 2 diabetes through a distinct adrenergic signaling pathway involving mTORC2 that mediates glucose uptake in skeletal muscle.

Interaction with Caveolin-1 Modulates G Protein Coupling of Mouse β3-Adrenoceptor ⬇️

Ligand-directed signaling at the beta3-adrenoceptor produced by 3-(2-Ethylphenoxy)-1-[(1,S)-1,2,3,4-tetrahydronapth-1-ylamino]-2S-2-propanol oxalate (SR59230A) relative to receptor agonists

ML290 is a biased allosteric agonist at the relaxin receptor RXFP1.

Memory processing in the avian hippocampus involves interactions between beta-adrenoceptors, glutamate receptors, and metabolism

Mirabegron: potential off target effects and uses beyond the bladder.

Noradrenaline release in the locus coeruleus modulates memory formation and consolidation; roles for α- and β-adrenergic receptors.

Orthosteric binding of ρ-Da1a, a natural peptide of snake venom interacting selectively with the α1A-adrenoceptor

Peripheral modulation of the endocannabinoid system in metabolic disease

Quantification of functional selectivity at the human α(1A)-adrenoceptor.

Rapid turnover of glycogen in memory formation

Response to Comment on Sato et al. Improving type 2 diabetes through a distinct adrenergic signaling pathway involving mTORC2 that mediates glucose uptake in skeletal muscle. Diabetes 2014;63:4115-4129.

Role of beta-adrenoceptors in memory consolidation: beta3-adrenoceptors act on glucose uptake and beta2-adrenoceptors on glycogenolysis

Role of β-adrenoceptors in glucose uptake in astrocytes using β-adrenoceptor knockout mice.

Rosiglitazone and a β3-Adrenoceptor Agonist Are Both Required for Functional Browning of White Adipocytes in Culture.

Shikonin increases glucose uptake in skeletal muscle cells and improves plasma glucose levels in diabetic Goto-Kakizaki rats

Signal transduction pathways activated by insulin-like peptide 5 at the relaxin family peptide RXFP4 receptor.

Stereoselectivity for interactions of agonists and antagonists at mouse, rat and human beta3-adrenoceptors

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15.

The Janus faces of adrenoceptors: factors controlling the coupling of adrenoceptors to multiple signal transduction pathways.

The M3-muscarinic acetylcholine receptor stimulates glucose uptake in L6 skeletal muscle cells by a CaMKK-AMPK-dependent mechanism

The PPARγ agonist rosiglitazone promotes the induction of brite adipocytes, increasing β-adrenoceptor-mediated mitochondrial function and glucose uptake.

The actions of relaxin family peptides on signal transduction pathways activated by the relaxin family peptide receptor RXFP4.

The beta3-adrenoceptor agonist 4-[[(Hexylamino)carbonyl]amino]-N-[4-[2-[[(2S)-2-hydroxy-3-(4-hydroxyphenoxy)propyl]amino]ethyl]-phenyl]-benzenesulfonamide (L755507) and antagonist (S)-N-[4-[2-[[3-[3-(acetamidomethyl)phenoxy]-2-hydroxypropyl]amino]-e

The metabolic effects of mirabegron are mediated primarily by β3 -adrenoceptors

Therapeutic blockade of activin-A improves NK cell function and antitumor immunity

beta(3)-adrenoceptor regulation and relaxation responses in mouse ileum

α1A-Adrenoceptors activate mTOR signalling and glucose uptake in cardiomyocytes.

α₂-Adrenoceptors activate noradrenaline-mediated glycogen turnover in chick astrocytes.

β1-Adrenergic receptors increase UCP1 in human MADS brown adipocytes and rescue cold-acclimated β3-adrenergic receptor-knockout mice via nonshivering thermogenesis

β2-Adrenoceptor-mediated regulation of glucose uptake in skeletal muscle--ligand-directed signalling or a reflection of system complexity?

β2‐Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C‐terminal tail ⬇️