List of works - Jacques-Antoine Haefliger

A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-Cells

scientific article (publication date: 2016)

A knowledge-based approach to automatic detection of the spinal cord in CT images.

scientific article published in December 2002

A new role for extracellular Ca2+ in gap-junction remodeling: studies in humans and rats

scientific article

Acute inflammation decreases the expression of connexin 40 in mouse lung.

scientific article

Atorvastatin-loaded hydrogel affects the smooth muscle cells of human veins

scientific article published on 26 September 2013

Cell-to-cell communications via connexins: function and alterations in endothelial and smooth muscle cells of vessels

scientific article published on 01 September 2000

Cellular localization, expression and regulation of neuropeptide Y in kidneys of hypertensive rats

scientific article published on 01 June 1999

Chronic hypertension alters the expression of Cx43 in cardiovascular muscle cells

scientific article published on 01 April 2000

Comparison of an LH-RH analogue (Goeserelin acetate, 'Zoladex') with combined androgen blockade in advanced prostate cancer: final survival results of an international multicentre randomized-trial. International Prostate Cancer Study Group

scientific article published on 01 February 2000

Comparison of the organization and fine structure of a chicken and a Xenopus laevis vitellogenin gene

scientific article published in November 1987

Complementary DNA cloning of complement C8 beta and its sequence homology to C9.

scholarly article

Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6

scientific article

Connexin 43 expression in human hypertrophied heart due to pressure and volume overload.

scientific article published on 27 February 2009

Connexin implication in the control of the murine beta-cell mass

scientific article published on 01 August 2011

Connexin-36 contributes to control function of insulin-producing cells.

scientific article published on 22 May 2003

Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity.

scientific article published on 4 October 2013

Connexin37 in normal and pathological development of mouse heart and great arteries

scientific article published on 01 June 2000

Connexin37-Dependent Mechanisms Selectively Contribute to Modulate Angiotensin II -Mediated Hypertension

scientific article published on 01 April 2019

Connexin40 regulates renin production and blood pressure

scientific article published on 11 July 2007

Connexin43 Inhibition Prevents Human Vein Grafts Intimal Hyperplasia

scientific article published on 23 September 2015

Connexin43-dependent mechanism modulates renin secretion and hypertension

scientific article

Connexins 40 and 43 are differentially regulated within the kidneys of rats with renovascular hypertension

scientific article published on 01 July 2001

Connexins 43 and 26 are differentially increased after rat bladder outlet obstruction

scientific article published in April 2002

Connexins and M3 muscarinic receptors contribute to heterogeneous Ca(2+) signaling in mouse aortic endothelium

scientific article published on 01 February 2013

Connexins protect mouse pancreatic β cells against apoptosis.

scientific article published on 7 November 2011

Contribution of connexins to the function of the vascular wall.

scientific article published on May 2004

Cx36 and the function of endocrine pancreas

scientific journal article

Cx36 is a target of Beta2/NeuroD1, which associates with prenatal differentiation of insulin-producing β cells.

scientific article

Cx36 preferentially connects beta-cells within pancreatic islets

scientific article published on 01 May 2000

Effects of chronic atrial fibrillation on gap junction distribution in human and rat atria

scientific article published on 01 September 2001

Endothelial Connexin37 and Connexin40 participate in basal but not agonist-induced NO release.

scientific article published on 22 July 2015

Ex vivo pulsatile perfusion of human saphenous veins induces intimal hyperplasia and increased levels of the plasminogen activator inhibitor 1.

scientific article published on 28 August 2010

Expression and regulation of connexins in cultured ventricular myocytes isolated from adult rat hearts

scientific article published on 15 January 2002

Expression of connexin36 in the adult and developing rat brain.

scientific article published in May 2000

Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping ⬇️

scientific article (publication date: 25 January 1992)

Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells.

scientific article published on 3 April 2008

Glucose represses connexin36 in insulin-secreting cells.

scientific article published on November 2005

Hyperglycemia downregulates Connexin36 in pancreatic islets via the upregulation of ICER-1/ICER-1γ.

scientific article published on 17 May 2013

Hypertension differentially affects the expression of the gap junction protein connexin43 in cardiac myocytes and aortic smooth muscle cells

scientific article published on 01 January 1997

Hypertension increases connexin43 in a tissue-specific manner

scientific article published on 01 February 1997

Hypoxic contraction of small pulmonary arteries from normal and endotoxemic rats: fundamental role of NO

scientific article published on 01 April 1999

ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells.

scientific article published on 11 December 2007

In vivoin vitro effects of somatostatin and insulin on glucagon release in a human glucagonoma ⬇️

scientific article published on May 1, 1997

Increased connexin43 expression in human saphenous veins in culture is associated with intimal hyperplasia

scientific article published in June 2005

Increased expression of renal cyclooxygenase-2 and neuronal nitric oxide synthase in hypertensive Cx40-deficient mice.

scientific article published on 24 September 2008

Increased vulnerability to kainic acid-induced epileptic seizures in mice underexpressing the scaffold protein Islet-Brain 1/JIP-1.

scientific article

Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor.

scientific article

Insulin-secreting beta-cell dysfunction induced by human lipoproteins

scientific article published on 18 February 2003

Insulinoma Associated with a Case of Multiple Endocrine Neoplasia Type I: Functional Somatostatin Receptors and Abnormal Glucose-Induced Insulin Secretion ⬇️

scientific article published on January 1, 1997

Intercellular calcium waves in primary cultured rat mesenteric smooth muscle cells are mediated by connexin43.

scientific article published on April 2012

Interplay between connexin40 and nitric oxide signaling during hypertension.

scientific article

Intravaginal and subcutaneous immunization induced vaccine specific CD8 T cells and tumor regression in the bladder.

scientific article

Intravesical Ty21a Vaccine Promotes Dendritic Cells and T Cell-Mediated Tumor Regression in the MB49 Bladder Cancer Model

scientific article published on 29 January 2019

Islet-brain1/JNK-interacting protein-1 is required for early embryogenesis in mice

scientific article published on 4 June 2001

Isolation and complete structure of the lymphocyte serine protease granzyme G, a novel member of the granzyme multigene family in murine cytolytic T lymphocytes. Evolutionary origin of lymphocyte proteases.

scientific article published on September 1989

Lack of association between connexin40 polymorphisms and coronary artery disease

scientific article published on 8 February 2012

Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta.

scientific article published on 27 August 2010

Neuronal traits are required for glucose-induced insulin secretion

scientific article published on May 2004

Neuropeptide Y secretion from a human insulinoma

scientific article published on 01 March 1996

Nitric Oxide Deficit Drives Intimal Hyperplasia in Mouse Models of Hypertension

scientific article

Perivascular sustained release of atorvastatin from a hydrogel-microparticle delivery system decreases intimal hyperplasia

scientific article

Phosphorylation-dependent dimerization and subcellular localization of islet-brain 1/c-Jun N-terminal kinase-interacting protein 1.

scientific article published in December 2007

Procedure for human saphenous veins ex vivo perfusion and external reinforcement

scientific article published in October 2014

REST represses a subset of the pancreatic endocrine differentiation program.

scientific article published on 5 July 2015

Reassessing the role of Staphylococcus aureus clumping factor and fibronectin-binding protein by expression in Lactococcus lactis.

scientific article

Reduction of connexin36 content by ICER-1 contributes to insulin-secreting cells apoptosis induced by oxidized LDL particles

scientific article (publication date: 2013)

Release of macrophage migration inhibitory factor by neuroendocrine-differentiated LNCaP cells sustains the proliferation and survival of prostate cancer cells.

scientific article

Renin and angiotensin II receptor gene expression in kidneys of renal hypertensive rats

scientific article published on 01 November 1995

Restoration of connexin 40 (Cx40) in Renin-producing cells reduces the hypertension of Cx40 null mice

scientific article published on 10 March 2014

Role of Connexins and Pannexins in the Pancreas.

scientific article

Role of hemodynamic forces in the ex vivo arterialization of human saphenous veins.

scientific article published on 23 January 2013

Sepsis up-regulates the expression of connexin 40 in rat aortic endothelium.

scientific article published in June 2005

Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain

scientific journal article

Specific silencing of the REST target genes in insulin-secreting cells uncovers their participation in beta cell survival

scientific article

Splice variant-specific stabilization of JNKs by IB1/JIP1.

scientific article published on 31 July 2007

Sporadic cases of dilated cardiomyopathies associated with atrioventricular conduction defects are not linked to mutation within the connexins 40 and 43 genes.

scientific article published in December 1999

Store-operated Ca2+ Entry Mediated by Orai1 and TRPC1 Participates to Insulin Secretion in Rat β-Cells.

scientific article

Structural and functional characterization of complement c8γ, a member of the lipocalin protein family ⬇️

scientific article published on January 1, 1991

Structural homology of human complement component C8 gamma and plasma protein HC: identity of the cysteine bond pattern

scientific article published in December 1987

Swimming prevents vulnerable atherosclerotic plaque development in hypertensive 2-kidney, 1-clip mice by modulating angiotensin II type 1 receptor expression independently from hemodynamic changes

scientific article

Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion

scientific article published on 13 February 2016

The processing routes determined by negatively charged residues in DR1-restricted T cell determinants.

scientific article published on October 1997

The repressor element silencing transcription factor (REST)-mediated transcriptional repression requires the inhibition of Sp1.

scientific article published on 4 November 2004

The scaffold protein IB1/JIP-1 controls the activation of JNK in rat stressed urothelium.

scientific article published in January 2002

The transcriptional repressor REST determines the cell-specific expression of the human MAPK8IP1 gene encoding IB1 (JIP-1)

scientific article

Tumor-Microenvironment Characterization of the MB49 Non-Muscle-Invasive Bladder-Cancer Orthotopic Model towards New Therapeutic Strategies

scientific article published in 2022

Variations in IB1/JIP1 expression regulate susceptibility of beta-cells to cytokine-induced apoptosis irrespective of C-Jun NH2-terminal kinase signaling

scientific article

[Connexins, renin and hypertension].

scientific article

[Gap functions and diseases]

scientific article published on 01 April 2005

[Gap junctions and secretion]

scientific article published on 01 April 2005

[Is molecular biology useful to the practitioner?]

scientific article published on 01 March 1997

List of works by Jacques-Antoine Haefliger

A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing β-Cells

A knowledge-based approach to automatic detection of the spinal cord in CT images.

A new role for extracellular Ca2+ in gap-junction remodeling: studies in humans and rats

Acute inflammation decreases the expression of connexin 40 in mouse lung.

Atorvastatin-loaded hydrogel affects the smooth muscle cells of human veins

Cell-to-cell communications via connexins: function and alterations in endothelial and smooth muscle cells of vessels

Cellular localization, expression and regulation of neuropeptide Y in kidneys of hypertensive rats

Chronic hypertension alters the expression of Cx43 in cardiovascular muscle cells

Comparison of an LH-RH analogue (Goeserelin acetate, 'Zoladex') with combined androgen blockade in advanced prostate cancer: final survival results of an international multicentre randomized-trial. International Prostate Cancer Study Group

Comparison of the organization and fine structure of a chicken and a Xenopus laevis vitellogenin gene

Complementary DNA cloning of complement C8 beta and its sequence homology to C9.

Complete primary structure and functional characterization of the sixth component of the human complement system. Identification of the C5b-binding domain in complement C6

Connexin 43 expression in human hypertrophied heart due to pressure and volume overload.

Connexin implication in the control of the murine beta-cell mass

Connexin-36 contributes to control function of insulin-producing cells.

Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity.

Connexin37 in normal and pathological development of mouse heart and great arteries

Connexin37-Dependent Mechanisms Selectively Contribute to Modulate Angiotensin II -Mediated Hypertension

Connexin40 regulates renin production and blood pressure

Connexin43 Inhibition Prevents Human Vein Grafts Intimal Hyperplasia

Connexin43-dependent mechanism modulates renin secretion and hypertension

Connexins 40 and 43 are differentially regulated within the kidneys of rats with renovascular hypertension

Connexins 43 and 26 are differentially increased after rat bladder outlet obstruction

Connexins and M3 muscarinic receptors contribute to heterogeneous Ca(2+) signaling in mouse aortic endothelium

Connexins protect mouse pancreatic β cells against apoptosis.

Contribution of connexins to the function of the vascular wall.

Cx36 and the function of endocrine pancreas

Cx36 is a target of Beta2/NeuroD1, which associates with prenatal differentiation of insulin-producing β cells.

Cx36 preferentially connects beta-cells within pancreatic islets

Effects of chronic atrial fibrillation on gap junction distribution in human and rat atria

Endothelial Connexin37 and Connexin40 participate in basal but not agonist-induced NO release.

Ex vivo pulsatile perfusion of human saphenous veins induces intimal hyperplasia and increased levels of the plasminogen activator inhibitor 1.

Expression and regulation of connexins in cultured ventricular myocytes isolated from adult rat hearts

Expression of connexin36 in the adult and developing rat brain.

Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping ⬇️

Functional significance of repressor element 1 silencing transcription factor (REST) target genes in pancreatic beta cells.

Glucose represses connexin36 in insulin-secreting cells.

Hyperglycemia downregulates Connexin36 in pancreatic islets via the upregulation of ICER-1/ICER-1γ.

Hypertension differentially affects the expression of the gap junction protein connexin43 in cardiac myocytes and aortic smooth muscle cells

Hypertension increases connexin43 in a tissue-specific manner

Hypoxic contraction of small pulmonary arteries from normal and endotoxemic rats: fundamental role of NO

ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells.

In vivoin vitro effects of somatostatin and insulin on glucagon release in a human glucagonoma ⬇️

Increased connexin43 expression in human saphenous veins in culture is associated with intimal hyperplasia

Increased expression of renal cyclooxygenase-2 and neuronal nitric oxide synthase in hypertensive Cx40-deficient mice.

Increased vulnerability to kainic acid-induced epileptic seizures in mice underexpressing the scaffold protein Islet-Brain 1/JIP-1.

Insulin secretion is regulated by the glucose-dependent production of islet beta cell macrophage migration inhibitory factor.

Insulin-secreting beta-cell dysfunction induced by human lipoproteins

Insulinoma Associated with a Case of Multiple Endocrine Neoplasia Type I: Functional Somatostatin Receptors and Abnormal Glucose-Induced Insulin Secretion ⬇️

Intercellular calcium waves in primary cultured rat mesenteric smooth muscle cells are mediated by connexin43.

Interplay between connexin40 and nitric oxide signaling during hypertension.

Intravaginal and subcutaneous immunization induced vaccine specific CD8 T cells and tumor regression in the bladder.

Intravesical Ty21a Vaccine Promotes Dendritic Cells and T Cell-Mediated Tumor Regression in the MB49 Bladder Cancer Model

Islet-brain1/JNK-interacting protein-1 is required for early embryogenesis in mice

Isolation and complete structure of the lymphocyte serine protease granzyme G, a novel member of the granzyme multigene family in murine cytolytic T lymphocytes. Evolutionary origin of lymphocyte proteases.

Lack of association between connexin40 polymorphisms and coronary artery disease

Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta.

Neuronal traits are required for glucose-induced insulin secretion

Neuropeptide Y secretion from a human insulinoma

Nitric Oxide Deficit Drives Intimal Hyperplasia in Mouse Models of Hypertension

Perivascular sustained release of atorvastatin from a hydrogel-microparticle delivery system decreases intimal hyperplasia

Phosphorylation-dependent dimerization and subcellular localization of islet-brain 1/c-Jun N-terminal kinase-interacting protein 1.

Procedure for human saphenous veins ex vivo perfusion and external reinforcement

REST represses a subset of the pancreatic endocrine differentiation program.

Reassessing the role of Staphylococcus aureus clumping factor and fibronectin-binding protein by expression in Lactococcus lactis.

Reduction of connexin36 content by ICER-1 contributes to insulin-secreting cells apoptosis induced by oxidized LDL particles

Release of macrophage migration inhibitory factor by neuroendocrine-differentiated LNCaP cells sustains the proliferation and survival of prostate cancer cells.

Renin and angiotensin II receptor gene expression in kidneys of renal hypertensive rats

Restoration of connexin 40 (Cx40) in Renin-producing cells reduces the hypertension of Cx40 null mice

Role of Connexins and Pannexins in the Pancreas.

Role of hemodynamic forces in the ex vivo arterialization of human saphenous veins.

Sepsis up-regulates the expression of connexin 40 in rat aortic endothelium.

Spatial, temporal and subcellular localization of islet-brain 1 (IB1), a homologue of JIP-1, in mouse brain

Specific silencing of the REST target genes in insulin-secreting cells uncovers their participation in beta cell survival

Splice variant-specific stabilization of JNKs by IB1/JIP1.

Sporadic cases of dilated cardiomyopathies associated with atrioventricular conduction defects are not linked to mutation within the connexins 40 and 43 genes.

Store-operated Ca2+ Entry Mediated by Orai1 and TRPC1 Participates to Insulin Secretion in Rat β-Cells.

Structural and functional characterization of complement c8γ, a member of the lipocalin protein family ⬇️

Structural homology of human complement component C8 gamma and plasma protein HC: identity of the cysteine bond pattern