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List of works by João E. Fonseca

A complex case of hepatitis in a patient with systemic lupus erythematosus

scientific article published on 01 January 1999

A quantitative comparison of a bone remodeling model with dual-energy X-ray absorptiometry and analysis of the inter-individual biological variability of femoral neck T-score.

scientific article

ANKH and susceptibility to and severity of ankylosing spondylitis.

scientific article published on 15 November 2011

Alterations on peripheral blood B-cell subpopulations in very early arthritis patients.

scientific article published on 7 March 2010

Amyloidosis in a series of 964 Portuguese rheumatoid arthritis patients: comment on the article by Myllykangas-Luosujarvi et al

scientific article published on 01 August 2001

Ankylosing spondylitis susceptibility and severity--contribution of TNF gene promoter polymorphisms at positions -238 and -308.

scientific article

Anti-ribosomal P protein IgG autoantibodies in patients with systemic lupus erythematosus: diagnostic performance and clinical profile.

scientific article

Assessment of laboratory measurements and −308 TNFα gene promoter polymorphisms in normal bone mineral density

article

BAFF and TACI gene expression are increased in patients with untreated very early rheumatoid arthritis

scientific article published on 15 June 2013

Bilateral Evaluation of the Hand and Wrist in Untreated Early Inflammatory Arthritis: A Comparative Study of Ultrasonography and Magnetic Resonance Imaging

scientific article published on 01 June 2013

Bilateral MR imaging of the hand and wrist in early and very early inflammatory arthritis: tenosynovitis is associated with progression to rheumatoid arthritis.

scientific article published on 21 June 2012

Biomechanical effects of inflammatory diseases on bone-rheumatoid arthritis as a paradigm.

scientific article published on 15 February 2009

Biosimilar DMARDs: What Does the Future Hold?

scientific article published on 3 March 2016

Chronic arthritis leads to disturbances in the bone collagen network.

scientific article

Comparative effectiveness and predictors of response to tumour necrosis factor inhibitor therapies in rheumatoid arthritis.

scientific article

Contribution for new genetic markers of rheumatoid arthritis activity and severity: sequencing of the tumor necrosis factor-alpha gene promoter

scientific article published in January 2007

Cross-sectional study of 50 patients with calcium pyrophosphate dihydrate crystal arthropathy

scientific article

Cytokine pattern in very early rheumatoid arthritis favours B-cell activation and survival.

scientific article published on 2 November 2010

Delayed neutrophil apoptosis in very early rheumatoid arthritis patients is abrogated by methotrexate therapy

scientific article published in November 2007

Dexamethasone treatment does not improve the outcome of women with HELLP syndrome: a double-blind, placebo-controlled, randomized clinical trial

scientific article published in November 2005

Dual effects of caspase-1, interleukin-1 beta, tumour necrosis factor-alpha and nerve growth factor receptor in inflammatory myopathies

scientific article published on 01 January 2003

Dynamic contrast-enhanced 3-T magnetic resonance imaging: a method for quantifying disease activity in early polyarthritis

scientific article published on 12 February 2011

Early vascular alterations in SLE and RA patients--a step towards understanding the associated cardiovascular risk

scientific article

Effect of Tumor Necrosis Factor Inhibitor Therapy on Osteoclasts Precursors in Rheumatoid Arthritis

scientific article published on 13 February 2017

Effectiveness and long-term retention of anti-tumour necrosis factor treatment in juvenile and adult patients with juvenile idiopathic arthritis: data from Reuma.pt.

scientific article

Effectiveness of a Referral Program for rheumatoid arthritis and axial spondyloarthritis Diagnosis at Primary Care Centers in Portugal - SIARA STUDY.

scientific article published on 5 March 2018

EpiReumaPt- the study of rheumatic and musculoskeletal diseases in Portugal: a detailed view of the methodology.

scientific article published in April 2015

Factors influencing calcaneus quantitative ultrasound measurements in an urban population.

scientific article

Fibrodysplasia ossificans progressiva: report of two cases

scientific article

Gender-specific effects of genetic variants within Th1 and Th17 cell-mediated immune response genes on the risk of developing rheumatoid arthritis

scientific article

Genetic Predictors of Poor Prognosis in Portuguese Patients with Juvenile Idiopathic Arthritis: Data from Reuma.pt

scientific article

Genome-wide association study and gene expression analysis identifies CD84 as a predictor of response to etanercept therapy in rheumatoid arthritis

scientific article

Global Functional Status in Rheumatoid Arthritis: Disease Duration and Patient Age

scientific article published on 01 February 2002

HLA alleles and HLA-B27 haplotypes associated with susceptibility and severity of ankylosing spondylitis in a Portuguese population.

scientific article published in December 2013

Hemorheological parameters are related to subclinical atherosclerosis in systemic lupus erythematosus and rheumatoid arthritis patients

scientific article published on 22 August 2011

Histology of the synovial tissue: value of semiquantitative analysis for the prediction of joint erosions in rheumatoid arthritis.

scientific article published in September 2000

Identification of La ribonucleoproteins as a component of interchromatin granules

scientific article published in November 1989

Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis.

scientific article

Inflammatory cell infiltrate and RANKL/OPG expression in rheumatoid synovium: comparison with other inflammatory arthropathies and correlation with outcome.

scientific article published in March 2005

Influence of human leucocyte antigen-DRB1 on the susceptibility to rheumatoid arthritis and on the production of anti-cyclic citrullinated peptide antibodies in a Portuguese population

scientific article published on 22 June 2006

Integration of sequence data from a Consanguineous family with genetic data from an outbred population identifies PLB1 as a candidate rheumatoid arthritis risk gene

scientific article

Interleukin-6 as a key player in systemic inflammation and joint destruction.

scientific article published on 02 February 2009

Interleukin-6 promoter polymorphism −174 G/C is associated with nephritis in Portuguese Caucasian systemic lupus erythematosus patients

article

Low bone mineral density in professional scuba divers

scientific article published on 13 January 2004

Low osteocalcin/collagen type I bone gene expression ratio is associated with hip fragility fractures.

scientific article published on 5 September 2012

Lymphotoxin-α 252 A>G polymorphism: a link between disease susceptibility and dyslipidemia in rheumatoid arthritis?

scientific article published in April 2011

Macrophage subpopulations in rheumatoid synovium: reduced CD163 expression in CD4+ T lymphocyte-rich microenvironments.

scientific article

Methotrexate treatment in rheumatoid arthritis: management in clinical remission, common infection and tuberculosis. Results from a systematic literature review.

scientific article published on 08 February 2010

Modulation of IL-17 and Foxp3 expression in the prevention of autoimmune arthritis in mice

scientific article

Mounting data indicate that antimalarials do not prevent mild or severe COVID-19 in rheumatic patients. Response to: 'The role of antimalarials in COVID-19: observational data from a cohort of rheumatic patients' by Favalli et al

scientific article published on 19 June 2020

Neutrophils in rheumatoid arthritis: More than simple final effectors.

scientific article published on 07 January 2010

Normative data for quantitative ultrasound measurement of the calcaneus in a Portuguese population

scientific article

Old drugs, old problems: where do we stand in prediction of rheumatoid arthritis responsiveness to methotrexate and other synthetic DMARDs?

scientific article

Osteoblasts and bone formation.

scientific article

Pachydermoperiostosis in an African patient caused by a Chinese/Japanese SLCO2A1 mutation-case report and review of literature

scientific article published on 05 September 2013

Patient's access to healthcare and treatment in rheumatoid arthritis: the views of stakeholders in Portugal.

scientific article

Patients' access to biologics in rheumatoid arthritis: a comparison between Portugal and other European countries

scientific article

Persistent low grade synovitis without erosive progression in magnetic resonance imaging of rheumatoid arthritis patients treated with infliximab over 1 year

scientific article published on 06 June 2009

Pharmacoeconomics of Biosimilars: What Is There to Gain from Them?

scientific article

Polymorphism at position -308 of the tumour necrosis factor alpha gene and rheumatoid arthritis pharmacogenetics.

scientific article published in May 2005

Potent anti-inflammatory and antiproliferative effects of gambogic acid in a rat model of antigen-induced arthritis

scientific article published on 30 January 2014

Predictors of response and anti-TNF drugs comparative efficacy.

scientific article published on 23 November 2011

Primary biliary cirrhosis in a rheumatoid arthritis patient treated with rituximab, a case-based review

scientific article published on 26 October 2011

Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals

scientific article

Real-world Longterm Effectiveness of Tumor Necrosis Factor Inhibitors in Psoriatic Arthritis Patients from the Rheumatic Diseases Portuguese Register

scientific article published on 01 August 2019

Rebalancing bone turnover in favour of formation with strontium ranelate: implications for bone strength.

scientific article

Reinnervation of post-arthritic joints in the rat

scientific article published on 01 January 1996

Rheumatoid arthritis: what is refractory disease and how to manage it?

scientific article published on 05 May 2011

Rheumatology practice amidst the COVID-19 pandemic: a pragmatic view

scientific article published on 01 June 2020

Rituximab use in pediatric autoimmune diseases: four case reports

scientific article

Severity of rheumatoid arthritis in Portuguese patients: Comment on the article by Drosos et al and on the letter by Ronda et al

scientific article published in February 2000

Should Rheumatoid Arthritis patients be systematically screened for the presence of other autoimmune diseases?

scientific article published on 01 April 2007

Smoking is a predictor of worse trabecular mechanical performance in hip fragility fracture patients.

scientific article published on 14 August 2012

Soluble receptor activator of nuclear factor κB ligand/osteoprotegerin ratio is increased in systemic lupus erythematosus patients

scientific article published on 25 October 2011

Spectrum of ankylosing spondylitis in Portugal. Development of BASDAI, BASFI, BASMI and mSASSS reference centile charts.

scientific article published on 19 October 2011

TNF promoter -308 G>A and LTA 252 A>G polymorphisms in Portuguese patients with systemic lupus erythematosus

article

TRAF1/C5 locus is associated with response to anti-TNF in rheumatoid arthritis

article

TYK2 protein-coding variants protect against rheumatoid arthritis and autoimmunity, with no evidence of major pleiotropic effects on non-autoimmune complex traits

scientific article

The EULAR Study Group for Registers and Observational Drug Studies: comparability of the patient case mix in the European biologic disease modifying anti-rheumatic drug registers

scientific article published on 27 November 2014

The Portuguese version of the Childhood Health Assessment Questionnaire (CHAQ) and the Child Health Questionnaire (CHQ).

scientific article

Treating Rheumatoid Arthritis to Target: multinational recommendations assessment questionnaire

scientific article published on 29 July 2011

Tumor necrosis factor-alpha -308 genotypes influence inflammatory activity and TNF-alpha serum concentrations in children with juvenile idiopathic arthritis

scientific article published on 22 January 2009

Upregulation of inflammatory genes and downregulation of sclerostin gene expression are key elements in the early phase of fragility fracture healing.

scientific article

Using the Juvenile Arthritis Disease Activity Score based on erythrocyte sedimentation rate or C-reactive protein level: results from the Portuguese register

scientific article published in April 2014

Vasculitis-like syndrome associated with Borrelia lusitaniae infection

scientific article

Whole blood transcriptional profiling in ankylosing spondylitis identifies novel candidate genes that might contribute to the inflammatory and tissue-destructive disease aspects

scientific article

[Acta Reumatológica Portuguesa: new horizons].

scientific article published in October 2006

[Diagnosis and treatment of osteoporosis in childhood]

article

[Eating habits and life styles in a Portuguese population--protective and risk factors for osteoporosis]

article

[Guidelines for prescribing and monitoring biologic therapies in juvenile idiopathic arthritis]

scientific article published on 01 January 2007

[Guidelines for the diagnosis and treatment of latent tuberculosis infection and active tuberculosis in patients with inflammatory joint diseases proposed for treatment with tumour necrosis factor alpha antagonist drugs]

article

[Is the response to anti-TNFalpha treatment influenced by the presence of IgM rheumatoid factor, in Rheumatoid Arthritis patients?]

scientific article published on 01 October 2008

[Juvenile cutaneous polyarteritis nodosa associated with streptococcal infection]

article

[Progressive myositis ossificans. Stone man]

scientific article published on 01 July 2001

[Protocol for clinical monitoring of juvenile idiopathic arthritis]

scientific article published on 01 July 2007

[Protocol for clinical monitoring of rheumatoid arthritis [PMAR]--December 2007 update]

scientific article published on 01 October 2007

[Recommendations for the diagnosis and treatment of latent and active tuberculosis in patients with inflammatory joint diseases treated with tumour necrosis factor alpha inhibitors]

scientific article published on 01 July 2006

[Tuberculosis in rheumatic patients treated with tumour necrosis factor alpha antagonists: the Portuguese experience]

article

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