List of works - Sven Panke

A genetic replacement system for selection-based engineering of essential proteins

scientific article

A reduction in growth rate of Pseudomonas putida KT2442 counteracts productivity advances in medium-chain-length polyhydroxyalkanoate production from gluconate ⬇️

scientific article (publication date: 22 April 2011)

A separation-integrated cascade reaction to overcome thermodynamic limitations in rare-sugar synthesis.

scientific article published on 16 February 2015

Acoustofluidic medium exchange for preparation of electrocompetent bacteria using channel wall trapping

scientific article published on 09 November 2021

Adsorption behavior of a teicoplanin aglycone bonded stationary phase under harsh overload conditions

scientific article published on 31 March 2007

Analysis of modular bioengineered antimicrobial lanthipeptides at nanoliter scale

scientific article published on 01 April 2019

Archimedes' principle for characterisation of recombinant whole cell biocatalysts.

scientific article published on 14 February 2018

Asymmetric dihydroxylation of aryl olefins by sequential enantioselective epoxidation and regioselective hydrolysis with tandem biocatalysts

scientific article published on 20 February 2009

Biotechnological Development of a Practical Synthesis of Ethyl (S)-2-Ethoxy-3-(p-methoxyphenyl)propanoate (EEHP): Over 100-Fold Productivity Increase from Yeast Whole Cells to Recombinant Isolated Enzymes

article

Carbon metabolism and product inhibition determine the epoxidation efficiency of solvent-tolerant Pseudomonas sp. strain VLB120DeltaC.

scientific article published in December 2007

Characterization of the AlkS/P(alkB)-expression system as an efficient tool for the production of recombinant proteins in Escherichia coli fed-batch fermentations

scientific article published in February 2007

Circumventing the effect of product toxicity: development of a novel two-stage production process for the lantibiotic gallidermin.

scientific article published on 28 December 2006

Clavulanic acid decomposition is catalyzed by the compound itself and by its decomposition products

scientific article published in August 2008

Compartmentalization - A Prerequisite for Maintaining and Changing an Identity

scientific article published in January 2016

Development of a fermentation process based on a defined medium for the production of pregallidermin, a nontoxic precursor of the lantibiotic gallidermin

scientific article published on 6 March 2010

Development of a high cell-density protocol for the production of pregallidermin, a non-toxic precursor of the lantibiotic gallidermin

scientific article published on 20 November 2009

Directed evolution of artificial metalloenzymes for in vivo metathesis

scientific article

Efficient engineering of chromosomal ribosome binding site libraries in mismatch repair proficient Escherichia coli.

scientific article published on 26 September 2017

Efficient recovery of low endotoxin medium-chain-length poly([R]-3-hydroxyalkanoate) from bacterial biomass

scientific article published on 19 January 2007

Engineering in complex systems.

scientific article

Exploiting cell-free systems: Implementation and debugging of a system of biotransformations.

scientific article published in June 2010

Exploiting racemases.

scientific article

Forward design of a complex enzyme cascade reaction

scientific article (publication date: 28 September 2016)

High concentrations of clavulanic acid but not of its degradation products decrease glycerol consumption and oxygen uptake rates in cultures of Streptomyces clavuligerus

scientific article

Highly efficient production of rare sugars D-psicose and L-tagatose by two engineered D-tagatose epimerases.

scientific article

Identification and Characterisation of a pH-stable GFP.

scientific article published on 21 June 2016

In silico genome-scale reconstruction and validation of the Staphylococcus aureus metabolic network.

scientific article

Integrated operation of continuous chromatography and biotransformations for the generic high yield production of fine chemicals.

scientific article

Isolation of monoclonal microcarriers colonized by fluorescent E. coli.

scientific article

Model-based characterization of an amino acid racemase from Pseudomonas putida DSM 3263 for application in medium-constrained continuous processes

scientific article published in November 2007

Model-based identification of optimal operating conditions for amino acid simulated moving bed enantioseparation using a macrocyclic glycopeptide stationary phase

scientific article published on 12 April 2014

Multi-objective optimization for the economic production of d-psicose using simulated moving bed chromatography.

scientific article published on 14 April 2015

Nanosilver on nanostructured silica: Antibacterial activity and Ag surface area

scientific article published on June 2011

New insights on the reorganization of gene transcription in Pseudomonas putida KT2440 at elevated pressure

scientific article published on 28 March 2013

Novel method for high-throughput colony PCR screening in nanoliter-reactors

scientific article published on 12 March 2009

Online medium-throughput respirometry-based OTR measurements in magnetically stirred cultures

scientific article published in October 2007

Optimization of a blueprint for in vitro glycolysis by metabolic real-time analysis

scientific article published on 20 March 2011

Optimization of a whole-cell biocatalyst by employing genetically encoded product sensors inside nanolitre reactors.

scientific article published on 13 July 2015

Periplasmic Screening for Artificial Metalloenzymes.

scientific article

Pilot-scale production of (S)-styrene oxide from styrene by recombinant Escherichia coli synthesizing styrene monooxygenase.

scientific article published on October 2002

Plasmid replication based on the T7 origin of replication requires a T7 RNAP variant and inactivation of ribonuclease H

scientific article published on 01 August 2021

Putative regulatory sites unraveled by network-embedded thermodynamic analysis of metabolome data

scientific article (publication date: 2006)

Putting cells under pressure: a simple and efficient way to enhance the productivity of medium-chain-length polyhydroxyalkanoate in processes with Pseudomonas putida KT2440.

scientific article

Quantifying the origin of released Ag+ ions from nanosilver.

scientific article published on 29 October 2012

Quantitative analysis of bacterial medium-chain-length poly([R]-3-hydroxyalkanoates) by gas chromatography

scientific article published on 16 January 2007

Rational design of a bacterial import system for new-to-nature molecules

scientific article published in 2024

Rationally reduced libraries for combinatorial pathway optimization minimizing experimental effort.

scientific article

Robust at-line quantification of poly(3-hydroxyalkanoate) biosynthesis by flow cytometry using a BODIPY 493/503-SYTO 62 double-staining

scientific article

Semi-rational engineering of an amino acid racemase that is stabilized in aqueous/organic solvent mixtures

scientific article published on 03 June 2020

Simulated moving bed enantioseparation of amino acids employing memory effect-constrained chromatography columns

scientific article published on 9 March 2012

Suitability of teicoplanin-aglycone bonded stationary phase for simulated moving bed enantioseparation of racemic amino acids employing composition-constrained eluents

scientific article published on 24 February 2006

Synthetic biology-paths to moving forward

scientific article published on 01 August 2009

Systematic assignment of thermodynamic constraints in metabolic network models

scientific article

Systematic optimization of interface interactions increases the thermostability of a multimeric enzyme

scientific article published on 26 July 2013

The efficiency of recombinant Escherichia coli as biocatalyst for stereospecific epoxidation.

scientific article

The good of two worlds: increasing complexity in cell-free systems.

scientific article published on 28 March 2013

The production of fine chemicals by biotransformations.

scientific article

Towards functional orthogonalisation of protein complexes: individualisation of GroEL monomers leads to distinct quasihomogeneous single rings.

scientific article

Towards preparative asymmetric synthesis of beta-hydroxy-alpha-amino acids: L-allo-threonine formation from glycine and acetaldehyde using recombinant GlyA.

scientific article published on 21 May 2007

Trends and innovations in industrial biocatalysis for the production of fine chemicals.

scientific article published in August 2004

List of works by Sven Panke

A genetic replacement system for selection-based engineering of essential proteins

A reduction in growth rate of Pseudomonas putida KT2442 counteracts productivity advances in medium-chain-length polyhydroxyalkanoate production from gluconate ⬇️

A separation-integrated cascade reaction to overcome thermodynamic limitations in rare-sugar synthesis.

Acoustofluidic medium exchange for preparation of electrocompetent bacteria using channel wall trapping

Adsorption behavior of a teicoplanin aglycone bonded stationary phase under harsh overload conditions

Analysis of modular bioengineered antimicrobial lanthipeptides at nanoliter scale

Archimedes' principle for characterisation of recombinant whole cell biocatalysts.

Asymmetric dihydroxylation of aryl olefins by sequential enantioselective epoxidation and regioselective hydrolysis with tandem biocatalysts

Biotechnological Development of a Practical Synthesis of Ethyl (S)-2-Ethoxy-3-(p-methoxyphenyl)propanoate (EEHP): Over 100-Fold Productivity Increase from Yeast Whole Cells to Recombinant Isolated Enzymes

Carbon metabolism and product inhibition determine the epoxidation efficiency of solvent-tolerant Pseudomonas sp. strain VLB120DeltaC.

Characterization of the AlkS/P(alkB)-expression system as an efficient tool for the production of recombinant proteins in Escherichia coli fed-batch fermentations

Circumventing the effect of product toxicity: development of a novel two-stage production process for the lantibiotic gallidermin.

Clavulanic acid decomposition is catalyzed by the compound itself and by its decomposition products

Compartmentalization - A Prerequisite for Maintaining and Changing an Identity

Development of a fermentation process based on a defined medium for the production of pregallidermin, a nontoxic precursor of the lantibiotic gallidermin

Development of a high cell-density protocol for the production of pregallidermin, a non-toxic precursor of the lantibiotic gallidermin

Directed evolution of artificial metalloenzymes for in vivo metathesis

Efficient engineering of chromosomal ribosome binding site libraries in mismatch repair proficient Escherichia coli.

Efficient recovery of low endotoxin medium-chain-length poly([R]-3-hydroxyalkanoate) from bacterial biomass

Engineering in complex systems.

Exploiting cell-free systems: Implementation and debugging of a system of biotransformations.

Exploiting racemases.

Forward design of a complex enzyme cascade reaction

High concentrations of clavulanic acid but not of its degradation products decrease glycerol consumption and oxygen uptake rates in cultures of Streptomyces clavuligerus

Highly efficient production of rare sugars D-psicose and L-tagatose by two engineered D-tagatose epimerases.

Identification and Characterisation of a pH-stable GFP.

In silico genome-scale reconstruction and validation of the Staphylococcus aureus metabolic network.

Integrated operation of continuous chromatography and biotransformations for the generic high yield production of fine chemicals.

Isolation of monoclonal microcarriers colonized by fluorescent E. coli.

Model-based characterization of an amino acid racemase from Pseudomonas putida DSM 3263 for application in medium-constrained continuous processes

Model-based identification of optimal operating conditions for amino acid simulated moving bed enantioseparation using a macrocyclic glycopeptide stationary phase

Multi-objective optimization for the economic production of d-psicose using simulated moving bed chromatography.

Nanosilver on nanostructured silica: Antibacterial activity and Ag surface area

New insights on the reorganization of gene transcription in Pseudomonas putida KT2440 at elevated pressure

Novel method for high-throughput colony PCR screening in nanoliter-reactors

Online medium-throughput respirometry-based OTR measurements in magnetically stirred cultures

Optimization of a blueprint for in vitro glycolysis by metabolic real-time analysis

Optimization of a whole-cell biocatalyst by employing genetically encoded product sensors inside nanolitre reactors.

Periplasmic Screening for Artificial Metalloenzymes.

Pilot-scale production of (S)-styrene oxide from styrene by recombinant Escherichia coli synthesizing styrene monooxygenase.

Plasmid replication based on the T7 origin of replication requires a T7 RNAP variant and inactivation of ribonuclease H

Putative regulatory sites unraveled by network-embedded thermodynamic analysis of metabolome data

Putting cells under pressure: a simple and efficient way to enhance the productivity of medium-chain-length polyhydroxyalkanoate in processes with Pseudomonas putida KT2440.

Quantifying the origin of released Ag+ ions from nanosilver.

Quantitative analysis of bacterial medium-chain-length poly([R]-3-hydroxyalkanoates) by gas chromatography

Rational design of a bacterial import system for new-to-nature molecules

Rationally reduced libraries for combinatorial pathway optimization minimizing experimental effort.

Robust at-line quantification of poly(3-hydroxyalkanoate) biosynthesis by flow cytometry using a BODIPY 493/503-SYTO 62 double-staining

Semi-rational engineering of an amino acid racemase that is stabilized in aqueous/organic solvent mixtures

Simulated moving bed enantioseparation of amino acids employing memory effect-constrained chromatography columns

Suitability of teicoplanin-aglycone bonded stationary phase for simulated moving bed enantioseparation of racemic amino acids employing composition-constrained eluents

Synthetic biology-paths to moving forward

Systematic assignment of thermodynamic constraints in metabolic network models

Systematic optimization of interface interactions increases the thermostability of a multimeric enzyme

The efficiency of recombinant Escherichia coli as biocatalyst for stereospecific epoxidation.

The good of two worlds: increasing complexity in cell-free systems.

The production of fine chemicals by biotransformations.

Towards functional orthogonalisation of protein complexes: individualisation of GroEL monomers leads to distinct quasihomogeneous single rings.

Towards preparative asymmetric synthesis of beta-hydroxy-alpha-amino acids: L-allo-threonine formation from glycine and acetaldehyde using recombinant GlyA.

Trends and innovations in industrial biocatalysis for the production of fine chemicals.