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List of works by Sean Connell

16S rRNA mutations that confer tetracycline resistance in Helicobacter pylori decrease drug binding in Escherichia coli ribosomes

scientific article

A conserved rRNA switch is central to decoding site maturation on the small ribosomal subunit

scientific article published on 04 June 2021

A dedicated translation factor controls the synthesis of the global regulator Fis.

scientific article

A new tRNA intermediate revealed on the ribosome during EF4-mediated back-translocation

scientific article

Backbone and sidechain NMR assignments for the ribosome maturation factor RbfA from Escherichia coli

scientific article published on 15 July 2020

Crystallographic characterization of the ribosomal binding site and molecular mechanism of action of Hygromycin A.

scientific article

Erythromycin, roxithromycin, and clarithromycin: use of slow-binding kinetics to compare their in vitro interaction with a bacterial ribosomal complex active in peptide bond formation

scientific article published in March 2003

GTPase activation of elongation factor EF-Tu by the ribosome during decoding

scientific article

Head swivel on the ribosome facilitates translocation by means of intra-subunit tRNA hybrid sites

scientific article

Heteronuclear NMR investigations of dynamic regions of intact Escherichia coli ribosomes

scholarly article

Incidence of antibiotic resistance in Campylobacter jejuni isolated in Alberta, Canada, from 1999 to 2002, with special reference to tet(O)-mediated tetracycline resistance

scientific article published on September 2004

Inhibition of translation initiation complex formation by GE81112 unravels a 16S rRNA structural switch involved in P-site decoding

scientific article published on 6 April 2016

Mechanism of Tet(O)-mediated tetracycline resistance

scientific article

Protein synthesis at atomic resolution: mechanistics of translation in the light of highly resolved structures for the ribosome.

scientific article

Ribosomal protection proteins and their mechanism of tetracycline resistance

scientific article

Solid-state NMR enhanced by dynamic nuclear polarization as a novel tool for ribosome structural biology

Structural basis for interaction of the ribosome with the switch regions of GTP-bound elongation factors

scientific article

Structural characterization of an alternative mode of tigecycline binding to the bacterial ribosome

scientific article published on 9 March 2015

Structure and conformational variability of the mycobacterium tuberculosis fatty acid synthase multienzyme complex

scientific article

Structure of a 30S pre-initiation complex stalled by GE81112 reveals structural parallels in bacterial and eukaryotic protein synthesis initiation pathways

scientific article published on 15 December 2016

Structure of the ribosome-bound cricket paralysis virus IRES RNA.

scientific article

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning

scientific article

The tetracycline resistance protein Tet(o) perturbs the conformation of the ribosomal decoding centre

scientific article published in September 2002

Translational regulation via L11: molecular switches on the ribosome turned on and off by thiostrepton and micrococcin

scientific article