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List of works by Wooin Lee

A Cancer-Specific Variant of the SLCO1B3 Gene Encodes a Novel Human Organic Anion Transporting Polypeptide 1B3 (OATP1B3) Localized Mainly in the Cytoplasm of Colon and Pancreatic Cancer Cells

scientific article published on December 24, 2012

A common polymorphism in the bile acid receptor farnesoid X receptor is associated with decreased hepatic target gene expression

scientific article published on 22 May 2007

A phase I study of pegylated liposomal doxorubicin and temsirolimus in patients with refractory solid malignancies

scientific article

A phase I trial of SJG-136 (NSC#694501) in advanced solid tumors

scientific article

Activity‐Based Near‐Infrared Fluorescent Probe for LMP7: A Chemical Proteomics Tool for the Immunoproteasome in Living Cells

scientific article published on July 17, 2012

Cancer pharmacogenomics: powerful tools in cancer chemotherapy and drug development

scientific article (publication date: February 2005)

Connectivity map-based drug repositioning of bortezomib to reverse the metastatic effect of GALNT14 in lung cancer

scientific article published on 09 May 2020

Determination of chemically reduced pyrrolobenzodiazepine SJG-136 in human plasma by HPLC-MS/MS: application to an anticancer phase I dose escalation study

scientific article published on 01 January 2008

Development of peptide-based reversing agents for p-glycoprotein-mediated resistance to carfilzomib

scientific article

Differential interactions of nitric oxide donors with rat oxyhemoglobin

scientific article published on 01 August 1999

Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics.

scientific article

Effect of drug transporter genotypes on pravastatin disposition in European- and African-American participants

scientific article

Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition

scientific article

H727 cells are inherently resistant to the proteasome inhibitor carfilzomib, yet require proteasome activity for cell survival and growth

scientific article published on 11 March 2019

Hepatic uptake of the novel antifungal agent caspofungin

scientific article

Inhibitors of the immunoproteasome: current status and future directions

scientific article published on January 2013

Lack of critical involvement of endothelial nitric oxide synthase in vascular nitrate tolerance in mice.

scientific article published on January 2002

Mechanism-based partial inactivation of glutathione S-transferases by nitroglycerin: tyrosine nitration vs sulfhydryl oxidation

scientific article published in March 2003

Next-generation proteasome inhibitors for cancer therapy

scientific article published on 26 March 2018

Novel mechanistic insights into ectodomain shedding of EGFR Ligands Amphiregulin and TGF-α: impact on gastrointestinal cancers driven by secondary bile acids.

scientific article

Overexpression of OATP1B3 confers apoptotic resistance in colon cancer

scientific article published on December 2008

PSMB9 codon 60 polymorphisms have no impact on the activity of the immunoproteasome catalytic subunit B1i expressed in multiple types of solid cancer

scientific article

Phase I and pharmacokinetic study of IHL-305 (PEGylated liposomal irinotecan) in patients with advanced solid tumors

scientific article published on 02 September 2012

Phase I pharmacokinetic and pharmacodynamic study of SJG-136, a novel DNA sequence selective minor groove cross-linking agent, in advanced solid tumors.

scientific article

Polymer micelle formulation for the proteasome inhibitor drug carfilzomib: Anticancer efficacy and pharmacokinetic studies in mice.

scientific article

Polymorphisms in human organic anion-transporting polypeptide 1A2 (OATP1A2): implications for altered drug disposition and central nervous system drug entry

scientific article

Population pharmacokinetics of PEGylated liposomal CPT-11 (IHL-305) in patients with advanced solid tumors

scientific article

Role of hypoxia inducible factor-1α in the regulation of the cancer-specific variant of organic anion transporting polypeptide 1B3 (OATP1B3), in colon and pancreatic cancer.

scientific article published on 4 August 2013

Statistical methods for assays with limits of detection: Serum bile acid as a differentiator between patients with normal colons, adenomas, and colorectal cancer.

scientific article

The immunoproteasome: an emerging therapeutic target

scientific article published on December 2011

The orphan nuclear receptor HNF4alpha determines PXR- and CAR-mediated xenobiotic induction of CYP3A4

scientific article (publication date: February 2003)

Thymidylate synthase genotype-directed chemotherapy for patients with gastric and gastroesophageal junction cancers

scientific article

Transporters and renal drug elimination

scientific article published on January 2004

eNOS-dependent vascular interaction between nitric oxide and calcitonin gene-related peptide in mice: gender selectivity and effects on blood aggregation

scientific article published in January 2003