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List of works by Andrew Badley

Acquired T-cell sensitivity to TRAIL mediated killing during HIV infection is regulated by CXCR4-gp120 interactions.

scientific article published on July 2005

Altering cell death pathways as an approach to cure HIV infection

scientific article published on 11 July 2013

Analysis of HIV Protease Killing Through Caspase 8 Reveals a Novel Interaction Between Caspase 8 and Mitochondria

scientific article published on 27 December 2007

Anti-apoptotic mechanisms of HIV: lessons and novel approaches to curing HIV

scientific article published on 30 December 2012

Attenuated T-lymphocyte response to HIV therapy in individuals receiving HMG-CoA reductase inhibitors

scientific article published in May 2003

Augmented Curation of Unstructured Clinical Notes from a Massive EHR System Reveals Specific Phenotypic Signature of Impending COVID-19 Diagnosis

scientific article published on 23 April 2020

Benchmarking evolutionary tinkering underlying human-viral molecular mimicry shows multiple host pulmonary-arterial peptides mimicked by SARS-CoV-2

scientific article published on 02 October 2020

Beneficial effect of TRAIL on HIV burden, without detectable immune consequences

scientific article

Blockade of HERG channels by HIV protease inhibitors.

scientific article published on February 2005

Both HIV-Infected and Uninfected Cells Express TRAILshort, Which Confers TRAIL Resistance upon Bystander Cells within the Microenvironment

scientific article published on 20 December 2017

CD4 T Cells Treated with gp120 Acquire a CD45R0+/CD45RA+ Phenotype.

scientific article published on April 2009

COVID-associated pediatric hospitalization and ICU admission trends across a multi-state health system and the broader US population

CXCR4 Tropic HIV-1 gp120 Inhibition of SDF-1α-Induced Chemotaxis Requires Lck and is Associated with Cofilin Phosphorylation

scientific article

Can HIV Be Cured and Should We Try?

scientific article published on 2 May 2015

Cardiothoracic Transplant Recipient Mycoplasma hominis: An Uncommon Infection with Probable Donor Transmission.

scientific article

Casp8p41 and HIV.

scientific article published on 22 August 2015

Casp8p41 expression in primary T cells induces a proinflammatory response

scientific article published on June 2010

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation

scientific article

Casp8p41 generated by HIV protease kills CD4 T cells through direct Bak activation.

scientific article

Casp8p41: The Protean Mediator of Death in CD4 T-cells that Replicate HIV

scientific article

Choice of antiretroviral therapy differentially impacts survival of HIV-infected CD4 T cells

scientific article

Correction: Both HIV-Infected and Uninfected Cells Express TRAILshort, Which Confers TRAIL Resistance upon Bystander Cells within the Microenvironment

scientific article published on 13 July 2018

Development of monoclonal gammopathy precedes the development of Epstein-Barr virus-induced posttransplant lymphoproliferative disorder ⬇️

scientific article published on September 1, 1996

Differential effects of interleukin-7 and interleukin-15 on NK cell anti-human immunodeficiency virus activity

scientific article

Disseminated coccidioidomycosis in a liver transplant recipient with negative serology: use of polymerase chain reaction.

scientific article

Early changes in T-cell activation predict antiretroviral success in salvage therapy of HIV infection

scientific article

Elimination of senescent neutrophils by TNF-related apoptosis-inducing [corrected] ligand

scientific article published in July 2005

Extensive virologic and immunologic characterization in an HIV-infected individual following allogeneic stem cell transplant and analytic cessation of antiretroviral therapy: A case study.

scientific article published on 28 November 2017

Glycoprotein 120 binding to CXCR4 causes p38-dependent primary T cell death that is facilitated by, but does not require cell-associated CD4

scientific article published on 01 April 2007

HIV Protease Cleavage of Procaspase 8 is Necessary for Death of HIV-Infected Cells

scientific article published on January 2008

HIV Protease-Generated Casp8p41, When Bound and Inactivated by Bcl2, Is Degraded by the Proteasome.

scientific article published on 11 April 2018

HIV VprR77Q mutation does not influence clinical response of individuals initiating highly active antiretroviral therapy

scientific article published on July 2006

HIV elite control is associated with reduced TRAILshort expression

scientific article published on 01 September 2019

HIV gp120 induces, NF-kappaB dependent, HIV replication that requires procaspase 8

scientific article

HIV induces TRAIL sensitivity in hepatocytes

scientific article

HIV protease inhibitors impact on apoptosis.

scientific article published on January 2008

HIV protease inhibitors modulate apoptosis signaling in vitro and in vivo

scientific article published on May 2007

HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice

scientific article published on June 2008

HIV replication, inflammation, and the effect of starting antiretroviral therapy on plasma asymmetric dimethylarginine, a novel marker of endothelial dysfunction

scientific article

HIV-1 Tat protein suppresses cholangiocyte toll-like receptor 4 expression and defense against Cryptosporidium parvum

scientific article

Heme oxygenase-1 regulates the immune response to influenza virus infection and vaccination in aged mice

scientific article

How much gp120 is there?

scientific article published on 01 April 2010

Human immunodeficiency virus envelope protein Gp120 induces proliferation but not apoptosis in osteoblasts at physiologic concentrations.

scientific article

Human immunodeficiency virus reactivation by phorbol esters or T-cell receptor ligation requires both PKCalpha and PKCtheta

scientific article published on August 2005

Human immunodeficiency virus type 1 protease cleaves procaspase 8 in vivo

scientific article published on 18 April 2007

Increased thymic output in HIV-negative patients after antiretroviral therapy

scientific article published in September 2005

Increasing procaspase 8 expression using repurposed drugs to induce HIV infected cell death in ex vivo patient cells

scientific article

Infected cell killing by HIV-1 protease promotes NF-kappaB dependent HIV-1 replication

scientific article

Influence of mitochondrial control of apoptosis on the pathogenesis, complications and treatment of HIV infection

scientific article

Influence of proteasome inhibitors on apoptosis

scientific article

Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor

scientific article

Intracellular Casp8p41 content is inversely associated with CD4 T cell count

scientific article

Investigation of Efavirenz Discontinuation in Multi-ethnic Populations of HIV-positive Individuals by Genetic Analysis

scientific article

Isolation of a TRAIL antagonist from the serum of HIV-infected patients.

scientific article

Longitudinal laboratory testing tied to PCR diagnostics in COVID-19 patients reveals temporal evolution of distinctive coagulopathy signatures

scientific article published on 24 May 2020

MCP-1 is up-regulated in unstressed and stressed HO-1 knockout mice: Pathophysiologic correlates

scientific article published on 01 August 2005

Maintenance of the HIV Reservoir Is Antagonized by Selective BCL2 Inhibition

scientific article published on 22 March 2017

Making sense of how HIV kills infected CD4 T cells: implications for HIV cure

scientific article published on 3 July 2014

Mechanisms of HIV-associated lymphocyte apoptosis: 2010 ⬇️

scientific article published on November 11, 2010

Mitochondrion-mediated apoptosis in HIV-1 infection

scientific article

Nelfinavir/ritonavir reduces acinar injury but not inflammation during mouse caerulein pancreatitis

scientific article published on 12 March 2009

Patients with discordant responses to antiretroviral therapy have impaired killing of HIV-infected T cells.

scientific article

Plasma IL-6 levels following corticosteroid therapy as an indicator of ICU length of stay in critically ill COVID-19 patients

scientific article published on 15 March 2021

Polymorphism in tumor necrosis factor-related apoptosis-inducing ligand receptor 1 is associated with poor viral response to interferon-based hepatitis C virus therapy in HIV/hepatitis C virus-coinfected individuals.

scientific article

Porphyria cutanea tarda and human immunodeficiency virus: two cases associated with hepatitis C.

scientific article published in September 1998

Prime, Shock, and Kill: Priming CD4 T Cells from HIV Patients with a BCL-2 Antagonist before HIV Reactivation Reduces HIV Reservoir Size

scientific article published on 3 February 2016

Prophylaxis of cytomegalovirus infection in liver transplantation: a randomized trial comparing a combination of ganciclovir and acyclovir to acyclovir. NIDDK Liver Transplantation Database ⬇️

scientific article published on July 15, 1997

Rejection severity directly correlates with myocyte apoptosis in pig-to-baboon cardiac xenotransplantation

scientific article

Renal hemodynamic, inflammatory, and apoptotic responses to lipopolysaccharide in HO-1-/- mice

scientific article published in June 2007

Renal upregulation of HO-1 reduces albumin-driven MCP-1 production: implications for chronic kidney disease

scientific article published on 12 September 2006

Resistance to apoptosis: mechanism for the development of HIV reservoirs.

scientific article published on July 2003

SDF-1α degrades whereas glycoprotein 120 upregulates Bcl-2 interacting mediator of death extralong isoform: implications for the development of T cell memory

scientific article

Short communication: CD4 T cell declines occurring during suppressive antiretroviral therapy reflect continued production of Casp8p41.

scientific article

TRAIL dependent fratricidal killing of gp120 primed hepatocytes by HCV core expressing hepatocytes

scientific article

TRAILshort Protects against CD4 T Cell Death during Acute HIV Infection

scientific article published on 12 June 2019

The Biology of TRAIL and the Role of TRAIL-Based Therapeutics in Infectious Diseases

scientific article

The HIV-1-specific protein Casp8p41 induces death of infected cells through Bax/Bak

scientific article

The TRAIL to viral pathogenesis: the good, the bad and the ugly

scientific article

The human immunodeficiency virus type 1 tat protein enhances Cryptosporidium parvum-induced apoptosis in cholangiocytes via a Fas ligand-dependent mechanism

scientific article published on 21 November 2006

Transcriptional Regulation of the Human FasL Promoter-Enhancer Region ⬇️

scientific article published on February 20, 1998

Transient loss of HIV-1 DNA in an HIV-1 positive patient after kidney transplantation: A case report.

scientific article

Twenty years of human immunodeficiency virus care at the Mayo Clinic: Past, present and future

scientific article

Vpr R77Q is associated with long-term nonprogressive HIV infection and impaired induction of apoptosis

scientific article

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