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List of works by Karl Herrup

ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations

scientific article published on 26 December 2017

ATM is activated by ATP depletion and modulates mitochondrial function through NRF1

scientific article published on 14 January 2019

ATM is activated by ATP depletion and modulates mitochondrial function through NRF1

ATM loss disrupts the autophagy-lysosomal pathway

scientific article published on 05 August 2020

Abnormal Purkinje cell dendrites in lurcher chimeric mice result from a deafferentation-induced atrophy

scientific article published in March 1996

Accumulation of Cytoplasmic DNA Due to ATM Deficiency Activates the Microglial Viral Response System with Neurotoxic Consequences

scientific article published on 12 June 2019

Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence

scientific article published on 21 October 2019

CDK5 activator protein p25 preferentially binds and activates GSK3β

scientific article

Cell number in the inferior olive of nervous and leaner mutant mice

scientific article published on 01 January 2004

Context-Dependent Functions of E2F1: Cell Cycle, Cell Death, and DNA Damage Repair in Cortical Neurons

scientific article published on 15 February 2020

Cytoplasmic ATM in neurons modulates synaptic function

scientific article

DNA Repair Inhibition Leads to Active Export of Repetitive Sequences to the Cytoplasm Triggering an Inflammatory Response

scientific article published on 30 September 2021

DNA damage in the oligodendrocyte lineage and its role in brain aging

scientific article published on 25 May 2016

Dissecting complex genetic interactions that influence the Engrailed-1 limb phenotype

scientific article published in May 2004

EZH2-mediated H3K27 trimethylation mediates neurodegeneration in ataxia-telangiectasia

scientific article

Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice

scientific article published on 06 November 2018

Individual Cytokines Modulate the Neurological Symptoms of ATM Deficiency in a Region Specific Manner(1,2,3)

scientific article published on July 2015

Loopholes in the DNA contract kill neurons

scientific article

Marine bacterial extracts as a new rich source of drugs against Alzheimer's disease

scientific article published on 25 August 2019

Neurons in Vulnerable Regions of the Alzheimer's Disease Brain Display Reduced ATM Signaling.

scientific article published on January 2016

Nucleocytoplasmic Cdk5 is involved in neuronal cell cycle and death in post-mitotic neurons.

scientific article published on 15 April 2011

Optimized splitting of RNA sequencing data by species

Quantitative examination of the deep cerebellar nuclei in the staggerer mutant mouse.

scientific article published in June 1981

Re-imagining Alzheimer's disease - the diminishing importance of amyloid and a glimpse of what lies ahead.

scientific article

Regional variation and absence of large neurons in the cerebellum of the staggerer mouse

scientific article published on August 17, 1979

Selective vulnerability of neurons in primary cultures and in neurodegenerative diseases.

scientific article published on January 2008

Testing the Neuroprotective Properties of PCSO-524 Using a Neuronal Cell Cycle Suppression Assay

scientific article published on 24 January 2019

The Amyloid Precursor Protein Modulates the Position and Length of the Axon Initial Segment

The Mechanism of Relaxation by Viewing a Japanese Garden: A Pilot Study

scientific article published on 05 June 2020

The amyloid precursor protein modulates the position and length of the axon initial segment offering a new perspective on Alzheimer’s disease genetics

The case for rejecting the amyloid cascade hypothesis.

scientific article published on June 2015

The contributions of unscheduled neuronal cell cycle events to the death of neurons in Alzheimer's disease

scientific article published on January 2012