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List of works by Thomas T Perkins

A Surface-Coupled Optical Trap with 1-bp Precision via Active Stabilization

scientific article published in January 2017

Atomic force microscopy with sub-picoNewton force stability for biological applications.

scientific article

Back-scattered detection provides atomic-scale localization precision, stability, and registration in 3D.

scientific article published in October 2007

Bending and looping of long DNA by Polycomb repressive complex 2 revealed by AFM imaging in liquid

scientific article published on 01 April 2020

Direct Observation of the Reversible Two-State Unfolding and Refolding of an α/β Protein by Single-Molecule Atomic Force Microscopy

scientific article published in July 2015

Dynamics and multiple stable binding modes of DNA intercalators revealed by single-molecule force spectroscopy

scientific article published on 09 December 2011

FEATHER: Automated Analysis of Force Spectroscopy Unbinding and Unfolding Data via a Bayesian Algorithm

article

Force Spectroscopy with 9-μs Resolution and Sub-pN Stability by Tailoring AFM Cantilever Geometry.

scientific article

Force-activated DNA substrates for probing individual proteins interacting with single-stranded DNA.

scientific article

Going Vertical To Improve the Accuracy of Atomic Force Microscopy Based Single-Molecule Force Spectroscopy

scientific article

Hidden dynamics in the unfolding of individual bacteriorhodopsin proteins.

scientific article

High-Precision Single-Molecule Characterization of the Folding of an HIV RNA Hairpin by Atomic Force Microscopy

scientific article published on 24 September 2018

Imaging DNA Equilibrated onto Mica in Liquid Using Biochemically Relevant Deposition Conditions

scientific article published on 05 April 2019

Improved Force Spectroscopy Using Focused-Ion-Beam-Modified Cantilevers

scientific article published on 31 October 2016

Improved Free-Energy Landscape Quantification Illustrated with a Computationally Designed Protein-Ligand Interaction

scientific article

Improved free-energy landscape reconstruction of bacteriorhodopsin highlights local variations in unfolding energy.

scientific article published in March 2018

Improved single molecule force spectroscopy using micromachined cantilevers

scientific article published on 01 April 2014

Integrating a high-force optical trap with gold nanoposts and a robust gold-DNA bond

scientific article

Label-free optical imaging of membrane patches for atomic force microscopy.

scientific article

Nano-chemical infrared imaging of membrane proteins in lipid bilayers.

scientific article published on 2 December 2013

Optimizing 1-μs-Resolution Single-Molecule Force Spectroscopy on a Commercial Atomic Force Microscope

scientific article

Optimizing bead size reduces errors in force measurements in optical traps.

scientific article

Optimizing force spectroscopy by modifying commercial cantilevers: Improved stability, precision, and temporal resolution

scientific article published on 19 January 2016

Overstretching DNA at 65 pN does not require peeling from free ends or nicks

scientific article published on 05 January 2011

Precision surface-coupled optical-trapping assay with one-basepair resolution

scientific article

Quantifying the Initial Unfolding of Bacteriorhodopsin Reveals Retinal Stabilization

scientific article published on 09 January 2019

Rapid Characterization of a Mechanically Labile α-Helical Protein Enabled by Efficient Site-Specific Bioconjugation

scientific article

Relaxation of a single DNA molecule observed by optical microscopy

scientific article published in May 1994

Routine and timely sub-picoNewton force stability and precision for biological applications of atomic force microscopy.

scientific article

Self-diffusion of an entangled DNA molecule by reptation

scientific article published on 01 November 1995

Sequence-dependent nanometer-scale conformational dynamics of individual RecBCD-DNA complexes

scientific article published on 24 May 2016

Sequence-dependent pausing of single lambda exonuclease molecules.

scientific article

Single polymer dynamics in an elongational flow

scientific article

Single-molecule optical-trapping measurements with DNA anchored to an array of gold nanoposts.

scientific article

Single-molecule studies of RecBCD.

scientific article published in January 2010

Stabilization of an optical microscope to 0.1 nm in three dimensions

scientific article

Stretching of a single tethered polymer in a uniform flow

scientific article

TFIIA Changes the Conformation of the DNA in TBP/TATA Complexes and Increases their Kinetic Stability

scientific article published on 29 June 2007

Ultrastable atomic force microscopy: atomic-scale stability and registration in ambient conditions

scientific article

Ultrastable atomic force microscopy: improved force and positional stability.

scientific article

Ultrastable measurement platform: sub-nm drift over hours in 3D at room temperature.

scientific article published on June 2015

Ångström-precision optical traps and applications.

scientific article published on January 2014

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