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List of works by Nigel Stallard

A Comparison of Methods for Adaptive Treatment Selection

article published in 2008

A Practical Comparison of Group-Sequential and Adaptive Designs

scientific article published on 01 January 2005

A cluster randomised controlled trial of the efficacy of a brief walking intervention delivered in primary care: study protocol

scientific article

A cluster randomized controlled trial of the effectiveness and cost-effectiveness of intermediate care clinics for diabetes (ICCD): study protocol for a randomized controlled trial

scientific article

A comparison of methods for constructing confidence intervals after phase II/III clinical trials

scientific article published on 31 October 2013

A comparison of methods for treatment selection in seamless phase II/III clinical trials incorporating information on short-term endpoints

scientific article published on January 2015

A conditional error function approach for subgroup selection in adaptive clinical trials ⬇️

scientific article published on August 3, 2012

A confirmatory seamless phase II/III clinical trial design incorporating short-term endpoint information

scientific article published on 26 February 2010

A group-sequential design for clinical trials with treatment selection

article by Nigel Stallard & Tim Friede published 20 December 2008 in Statistics in Medicine

A hierarchical Bayesian model for predicting the functional consequences of amino-acid polymorphisms

article

A hybrid procedure for detecting global treatment effects in multivariate clinical trials: theory and applications to fMRI studies

scientific article published on 15 December 2011

A multi-stage drop-the-losers design for multi-arm clinical trials.

scientific article published on 16 September 2014

A new sighting study for the fixed concentration procedure to allow for gender differences

scientific article

A newly devised scoring system for prediction of mortality in patients with colorectal cancer: a prospective study

scientific article

A novel adaptive design strategy increases the efficiency of clinical trials in secondary progressive multiple sclerosis

scientific article published on 26 August 2010

A parametric multistate model for the analysis of carcinogenicity experiments

article

A statistical evaluation of the effects of gender differences in assessment of acute inhalation toxicity

scientific article

A study of the efficacy and cost-effectiveness of MRSA screening and monitoring on surgical wards using a new, rapid molecular test (EMMS).

scientific article

A systematic literature review of the risk factors associated with children entering public care

scientific article published on 05 December 2012

Action following the discovery of a global association between the whole genome and adverse event risk in a clinical drug-development programme

scientific article published on October 2009

Adaptive Multivariate Global Testing

scientific article published on 13 June 2014

Adaptive designs for clinical trials assessing biomarker-guided treatment strategies.

scientific article published on 25 March 2014

Adaptive designs for confirmatory clinical trials with subgroup selection.

scientific article published on January 2014

Adaptive seamless clinical trials using early outcomes for treatment or subgroup selection: Methods, simulation model and their implementation in R

scientific article published on 02 March 2020

Advanced life support cardiac arrest scenario test evaluation

scientific article published on 13 July 2007

An Adaptive Group Sequential Design for Phase II/III Clinical Trials that Select a Single Treatment From Several

article by Patrick J. Kelly et al published July 2005 in Journal of Biopharmaceutical Statistics

An R package for implementing simulations for seamless phase II/III clinical trials using early outcomes for treatment selection

An alternative approach to the analysis of animal carcinogenicity studies

scientific article published in June 1996

Approximately optimal designs for phase II clinical studies

scientific article published in July 1998

Bayesian graphical models for genomewide association studies

scientific article published on 30 May 2006

Bayesian modelling of multivariate quantitative traits using seemingly unrelated regressions

scientific article published in May 2005

Can we convert between outcome measures of disability for chronic low back pain?

scientific article published in May 2015

Changing case Order to Optimise patterns of Performance in mammography Screening (CO-OPS): study protocol for a randomized controlled trial

scientific article published on 10 January 2014

Clinical Trials in Oncology

Comments on the draft guidance on "adaptive design clinical trials for drugs and biologics" of the U.S. Food and Drug Administration

scientific article published in November 2010

Comparison of Bayesian and frequentist group-sequential clinical trial designs

scientific article published on 07 January 2020

Comparison of the spending function method and the Christmas tree correction for group sequential trials

scientific article published in July 1996

Conditionally unbiased estimation in phase II/III clinical trials with early stopping for futility

scientific article published on 15 February 2013

Correction

scholarly article published in Statistics in Medicine

Correction: ‘A conditional error function approach for subgroup selection in adaptive clinical trials’

Data-driven treatment selection for seamless phase II/III trials incorporating early-outcome data

scientific article

Decision-making in a phase II clinical trial: a new approach combining Bayesian and frequentist concepts

article

Decision-theoretic designs for phase II clinical trials allowing for competing studies

scientific article published in June 2003

Decision-theoretic designs for small trials and pilot studies: A review

scientific article published on 05 June 2015

Designing a seamless phase II/III clinical trial using early outcomes for treatment selection: an application in multiple sclerosis

scientific article

Designing a series of decision‐theoretic phase II trials in a small population ⬇️

scientific article published on August 24, 2012

Determination of the optimal sample size for a clinical trial accounting for the population size

scientific article published on 17 May 2016

Directions for new developments on statistical design and analysis of small population group trials

scientific article published on 14 June 2016

Dose selection in seamless phase II/III clinical trials based on efficacy and safety.

scientific article published in March 2009

Editorial for the Biometrical Journal Special Issue ISCB 2016

scientific article published on 01 March 2018

Effect of Using the Same vs Different Order for Second Readings of Screening Mammograms on Rates of Breast Cancer Detection: A Randomized Clinical Trial

scientific article published on May 2016

Effectiveness and cost-effectiveness of a universal parenting skills programme in deprived communities: multicentre randomised controlled trial

scientific article

Effectiveness of a web-based cognitive-behavioral tool to improve mental well-being in the general population: randomized controlled trial

scientific article published on 31 December 2012

Emergency nurse practitioners and doctors consulting with patients in an emergency department: a comparison of communication skills and satisfaction

scientific article published in June 2009

Estimating numbers of infectious units from serial dilution assays

article

Estimating the magnitude of carcinogenic effects in long-term animal studies.

scientific article

Estimation after subpopulation selection in adaptive seamless trials

scientific article published on 22 April 2015

Estimation following selection of the largest of two normal means

article

Evaluating the quality of subgroup analyses in randomized controlled trials of therapist-delivered interventions for nonspecific low back pain: a systematic review.

scientific article published on April 2014

Evaluating the relationship between moral values and vaccine hesitancy in Great Britain during the COVID-19 pandemic: A cross-sectional survey

scientific article published on 14 July 2022

Evaluation of the effectiveness and cost-effectiveness of Families for Health V2 for the treatment of childhood obesity: study protocol for a randomized controlled trial

scientific article published on 20 March 2013

Exact group-sequential designs for clinical trials with randomized play-the-winner allocation

scientific article published in February 2002

Exercise or manual physiotherapy compared with a single session of physiotherapy for osteoporotic vertebral fracture: three-arm PROVE RCT

scientific article published on 01 August 2019

Facet-joint injections for people with persistent non-specific low back pain (FIS): study protocol for a randomised controlled feasibility trial

scientific article

Flexible selection of a single treatment incorporating short-term endpoint information in a phase II/III clinical trial

scientific article

Flexible sequential designs for multi-arm clinical trials

article published in 2014

Group-Sequential Methods for Adaptive Seamless Phase II/III Clinical Trials ⬇️

scientific article published on July 1, 2011

HIV self-testing alone or with additional interventions, including financial incentives, and linkage to care or prevention among male partners of antenatal care clinic attendees in Malawi: An adaptive multi-arm, multi-stage cluster randomised trial

article

Health service use in families where children enter public care: a nested case control study using the General Practice Research Database

scientific article

How do hospital professionals involved in a randomised controlled trial perceive the value of genotyping vs. PCR-ribotyping for control of hospital acquired C. difficile infections?

scientific article

Improving the efficiency of advanced life support training: a randomized, controlled trial.

scientific article published in July 2012

In 'big bang' major incidents do triage tools accurately predict clinical priority?: a systematic review of the literature.

scientific article published on May 2011

Including a time-of-year effect in the analysis of a matched case-control study

scientific article published in October 2004

Interim analyses and sequential designs in phase III studies

scientific article

Local impact of the English arm of the UK Bowel Cancer Screening Pilot study

scientific article

Measuring the impact and costs of a universal group based parenting programme: protocol and implementation of a trial

scientific article

Methods for identification and confirmation of targeted subgroups in clinical trials: A systematic review

scientific article

Morbidity from diarrhoea, cough and fever among young children in Nigeria.

scientific article published in July 2008

Motor Neuron Disease Systematic Multi-Arm Adaptive Randomised Trial (MND-SMART): a multi-arm, multi-stage, adaptive, platform, phase III randomised, double-blind, placebo-controlled trial of repurposed drugs in motor neuron disease

scientific article published in 2022

OPTIMA prelim: a randomised feasibility study of personalised care in the treatment of women with early breast cancer

scientific article published in February 2016

Optimal adaptive designs for acute oral toxicity assessment

article

Optimal choice of the number of treatments to be included in a clinical trial

scientific article published in April 2009

Optimal sample sizes for phase II clinical trials and pilot studies

scientific article published on 3 November 2011

Optimized adaptive enrichment designs

scientific article published in January 2017

Parenting and health in mid-childhood: a longitudinal study

article

Performance characteristics of five triage tools for major incidents involving traumatic injuries to children.

scientific article published on 10 November 2015

Phase II Clinical Trials

Physiotherapy Rehabilitation for Osteoporotic Vertebral Fracture (PROVE): study protocol for a randomised controlled trial.

scientific article published on 14 January 2014

Physiotherapy rehabilitation for osteoporotic vertebral fracture-a randomised controlled trial and economic evaluation (PROVE trial)

scientific article published on 12 November 2019

Planning multi-arm screening studies within the context of a drug development program

scientific article published on 26 March 2013

Point estimates and confidence regions for sequential trials involving selection

article

Practical guidelines for adaptive seamless phase II/III clinical trials that use Bayesian methods

scientific article published on 22 March 2012

Recent advances in methodology for clinical trials in small populations: the InSPiRe project

scientific article published on 25 October 2018

Reducing animal numbers in the fixed-dose procedure

scientific article published in April 1995

Reduction in the rate of methicillin-resistant Staphylococcus aureus acquisition in surgical wards by rapid screening for colonization: a prospective, cross-over study

scientific article published in 2010

Refinement of the Clinical Scenario Evaluation Framework for Assessment of Competing Development Strategies with an Application to Multiple Sclerosis

article

Repeated challenge with prion disease: the risk of infection and impact on incubation period

scientific article

Repeated measures proportional odds logistic regression analysis of ordinal score data in the statistical software package R

scholarly article by Nick R. Parsons et al published January 2009 in Computational Statistics & Data Analysis

Sample Size Determination for Phase II Clinical Trials Based on Bayesian Decision Theory

scientific article published on March 1, 1998

Seamless phase II/III designs

scientific article published on 19 August 2010

Selecting breast cancer patients for chemotherapy: the opening of the UK OPTIMA trial.

scientific article published on 23 December 2012

Sequential designs for phase III clinical trials incorporating treatment selection

scientific article published in March 2003

Sequential genome-wide association studies for monitoring adverse events in the clinical evaluation of new drugs

article

Sequentially testing for a gene-drug interaction in a genomewide analysis

scientific article published in May 2008

Should randomised controlled trials be the “gold standard” for research on preventive interventions for children?

article by Sarah Stewart‐Brown et al published 9 December 2011 in Journal of Children s Services

Simple tests for the external validation of mortality prediction scores.

scientific article published in February 2009

Socioeconomic risk, parenting during the preschool years and child health age 6 years

scientific article published on 14 December 2006

Statistical design and analysis of pharmacogenetic trials

article

Statistical evaluation of an acute dermal toxicity test using the dermal fixed dose procedure

article

Statistical evaluation of the Fixed Concentration Procedure for acute inhalation toxicity assessment

article

Statistical evaluation of the revised fixed-dose procedure

Stopping rules for phase II studies

scientific article

Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions

scientific article

The System-Wide Effect of Real-Time Audiovisual Feedback and Postevent Debriefing for In-Hospital Cardiac Arrest: The Cardiopulmonary Resuscitation Quality Improvement Initiative

scientific article

The effect of real-time CPR feedback and post event debriefing on patient and processes focused outcomes: a cohort study: trial protocol

scientific article published on 18 October 2011

The effects of a brief intervention to promote walking on Theory of Planned Behavior constructs: a cluster randomized controlled trial in general practice

scientific article

The fixed-dose procedure and the acute-toxic-class method: a mathematical comparison

scientific article published in December 1995

Two-stage designs for phase II cancer trials with ordinal responses

scientific article

Using the NIHR Research Design Service

Utilizing rapid multiple-locus variable-number tandem-repeat analysis typing to aid control of hospital-acquired Clostridium difficile Infection: a multicenter study

scientific article

Value of information methods to design a clinical trial in a small population to optimise a health economic utility function.

scientific article published on 8 February 2018

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