List of works by Dominique Heymann

12b80 - Hydroxybisphosphonate Linked Doxorubicin: Bone Targeted Strategy for Treatment of Osteosarcoma

scientific article published on 10 May 2019

3D curved multiplanar cone beam CT reconstruction for intracochlear position assessment of straight electrodes array. A temporal bone and clinical study

scientific article published on 6 September 2016

99mTc-NTP 15-5 assessment of the early therapeutic response of chondrosarcoma to zoledronic acid in the Swarm rat orthotopic model

scientific article published on 20 May 2013

A Disintegrin And Metalloproteinase 12 produced by tumour cells accelerates osteosarcoma tumour progression and associated osteolysis

scientific article published on 13 March 2013

A One-Pot Synthesis of 1-Hydroxy-1,1-bis(phosphonic acid)s Starting from the Corresponding Carboxylic Acids

scientific article published on 25 October 2011

A combination of methotrexate and zoledronic acid prevents bone erosions and systemic bone mass loss in collagen induced arthritis

scientific article

A functional, new short isoform of death receptor 4 in Ewing's sarcoma cell lines may be involved in TRAIL sensitivity/resistance mechanisms

scientific article published on 18 January 2012

A new experimental rat model of osteosarcoma established by intrafemoral tumor cell inoculation, useful for biology and therapy investigations.

scientific article

Adapting palliative radiation therapy for bone metastases during the Covid-19 pandemic: GEMO position paper

scientific article published on 13 April 2020

Advantages of bioluminescence imaging to follow siRNA or chemotherapeutic treatments in osteosarcoma preclinical models

scientific article

Allele-specific Col1a1 silencing reduces mutant collagen in fibroblasts from Brtl mouse, a model for classical osteogenesis imperfecta

scientific article published on 11 September 2013

Analysis of gap junctional intercellular communications using a dielectrophoresis-based microchip

scientific article published on 6 February 2017

Anti-Metastatic Properties of a Marine Bacterial Exopolysaccharide-Based Derivative Designed to Mimic Glycosaminoglycans

scientific article published on 04 March 2016

Anti-PD1 therapy induces lymphocyte-derived exosomal miRNA-4315 release inhibiting Bim-mediated apoptosis of tumor cells

scientific article published on 11 December 2020

Anticancer activity of halofuginone in a preclinical model of osteosarcoma: inhibition of tumor growth and lung metastases

scientific article

Are Fluorescent Organic Nanoparticles Relevant Tools for Tracking Cancer Cells or Macrophages?

scientific article published on 9 November 2015

Association of human growth hormone and calcium phosphate by dynamic compaction:In vitro biocompatibility and bioactivity ⬇️

scientific article published on August 1, 1997

Autophagy in osteoblasts is involved in mineralization and bone homeostasis

scientific article published in January 2014

BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma

scientific article

Bidirectional regulation of bone formation by exogenous and osteosarcoma-derived Sema3A.

scientific article published on 2 May 2018

Biological activities of sustained polymyxin B release from calcium phosphate biomaterial prepared by dynamic compaction: an in vitro study

scientific article published in October 1999

Biology of Bone Sarcomas and New Therapeutic Developments

scientific article published on 13 December 2017

Bisphosphonates: new therapeutic agents for the treatment of bone tumors

scientific article published in July 2004

Blocking HSP90 Addiction Inhibits Tumor Cell Proliferation, Metastasis Development, and Synergistically Acts with Zoledronic Acid to Delay Osteosarcoma Progression

scientific article

Bone Morphogenetic Protein 2 and Transforming Growth Factor β1 Inhibit the Expression of the Proinflammatory Cytokine IL-34 in Rheumatoid Arthritis Synovial Fibroblasts

scientific article published on 17 November 2016

Bone Tumor Environment as a Potential Therapeutic Target in Ewing Sarcoma

scientific article

Bone microenvironment has an influence on the histological response of osteosarcoma to chemotherapy: retrospective analysis and preclinical modeling

scientific article published in November 2017

Bone remodelling and tumour grade modifications induced by interactions between bone and swarm rat chondrosarcoma

scientific article published in October 2002

Cancer stem cells in osteosarcoma

scientific article published on 25 November 2016

Caractérisation de la dormance d’une lignée cellulaire d’ostéosarcome en culture trois-dimensions

scientific article published in 2022

Carotid and femoral atherosclerotic plaques show different morphology

scientific article published in June 2011

Cell-free circulating epimarks in cancer monitoring

scientific article published on 09 January 2020

Cellular activity and signaling induced by osteoprotegerin in osteoclasts: involvement of receptor activator of nuclear factor kappaB ligand and MAPK.

scientific article published on February 2004

Characterization of osteoprotegerin binding to glycosaminoglycans by surface plasmon resonance: role in the interactions with receptor activator of nuclear factor kappaB ligand (RANKL) and RANK.

scientific article published on 30 June 2006

Circulating Tumor Cell-Derived Pre-Clinical Models for Personalized Medicine

Circulating Tumor Cells: A Review of Non-EpCAM-Based Approaches for Cell Enrichment and Isolation

scientific article published on 19 February 2016

Circulating Tumor Cells: The Importance of Single Cell Analysis

scientific article published in 2018

Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma

scientific article

Concise review: embryonic stem cells: a new tool to study osteoblast and osteoclast differentiation

scientific article published on 9 November 2006

Conditioned media from mouse osteosarcoma cells promote MC3T3-E1 cell proliferation using JAKs and PI3-K/Akt signal crosstalk

scientific article published on 18 October 2008

Connexin43 intercellular communication drives the early differentiation of human bone marrow stromal cells into osteoblasts

scientific article published on 30 March 2017

Constitutive expression of TNF-related activation-induced cytokine (TRANCE)/receptor activating NF-κB ligand (RANK)-L by rat plasmacytoid dendritic cells

scientific article

Culturing of cells from giant cell tumour of bone on natural and synthetic calcified substrata: the effect of leukaemia inhibitory factor and vitamin D3 on the resorbing activity of osteoclast-like cells

scientific article published in 1995

Current therapeutic strategies and novel approaches in osteosarcoma

scientific article published on 24 May 2013

Cysteine protease production by human osteosarcoma cells (MG63, SAOS2) and its modulation by soluble factors

scientific article published in May 2000

Cytokine production by human thymic epithelial cells: control by the immune recognition of the neurohypophysial self-antigen.

scientific article

Cytokines, growth factors and osteoclasts

scientific article published on March 1998

Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme

scientific article published on 25 February 2020

DU145 human prostate cancer cells express functional receptor activator of NFkappaB: new insights in the prostate cancer bone metastasis process

scientific article

Damage to inner ear structure during cochlear implantation: Correlation between insertion force and radio-histological findings in temporal bone specimens

scientific article published on 4 November 2016

Design and validation of a tunable inertial microfluidic system for the efficient enrichment of circulating tumor cells in blood

scientific article published in September 2022

Development of enzymo-immunoassays (EIA) for macrophage colony-stimulating factor (M-CSF) and leukaemia inhibitory factor (LIF) by using the same capture and signal generating polyclonal antibody

scientific article published in July 1996

Development of prohibitin ligands against osteoporosis ⬇️

scientific article published on 23 October 2020

Differentiation of osteoblasts from mouse embryonic stem cells without generation of embryoid body

scientific article published in January 2007

Direct anti-cancer effect of oncostatin M on chondrosarcoma.

scientific article published on 6 January 2011

Distinct roles of Bcl-2 and Bcl-Xl in the apoptosis of human bone marrow mesenchymal stem cells during differentiation

scientific article

Dormant, quiescent, tolerant and persister cells: four synonyms for the same target in cancer

scientific article published in November 2018

Downregulation of osteoblast markers and induction of the glial fibrillary acidic protein by oncostatin M in osteosarcoma cells require PKCdelta and STAT3.

scientific article

Drugs in early clinical development for the treatment of osteosarcoma

scientific article published on 15 September 2016

Drugs targeting the bone microenvironment: new therapeutic tools in Ewing's sarcoma?

scientific article published on 20 August 2013

Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma

scientific article

Effect of adding bone marrow to ceramic graft materials with different interconnectivities in lumbar arthrodesis : quantification of bone formation.

scientific article published in December 2012

Effects of leukemia inhibitory factor and oncostatin M on bone mineral formed in in vitro rat bone-marrow stromal cell culture: physicochemical aspects

scientific article published on 18 December 1998

Enhanced tumor regression and tissue repair when zoledronic acid is combined with ifosfamide in rat osteosarcoma

scientific article

Expression of leukemia inhibitory factor by cartilage-forming tumors of bone: an immunohistochemical study

scientific article published in March 1999

Extraosseous bone formation obtained by association of mesenchymal stem cells with a periosteal flap in the rat.

scientific article published in August 2007

Factor VIII-von Willebrand factor complex inhibits osteoclastogenesis and controls cell survival

scientific article published on 16 September 2009

Farnesyl diphosphate synthase is involved in the resistance to zoledronic acid of osteosarcoma cells

scientific article

First preclinical imaging of primary cartilage neoplasm and its local recurrence using 99mTc-NTP 15-5 radiotracer

scientific article

Formulated siRNAs targeting Rankl prevent osteolysis and enhance chemotherapeutic response in osteosarcoma models

scientific article published in October 2011

Genetically-achieved disturbances to the expression levels of TNFSF11 receptors modulate the effects of zoledronic acid on growing mouse skeletons

scientific article published on 28 June 2019

Glycosaminoglycans as potential regulators of osteoprotegerin therapeutic activity in osteosarcoma

scientific article

Glycosaminoglycans inhibit the adherence and the spreading of osteoclasts and their precursors: role in osteoclastogenesis and bone resorption

scientific article published on 20 October 2010

Growth hormone stimulates multinucleated cell formation in long-term bone marrow cultures

scientific article published in January 1998

Growth hormone stimulates the degradation of calcium phosphate biomaterial by human monocytes macrophagesin vitro

scientific article published in April 1998

Growth hormone-loaded macroporous calcium phosphate ceramic: in vitro biopharmaceutical characterization and preliminary in vivo study

scientific article published on 15 June 1998

Hamstring insertion site healing after anterior cruciate ligament reconstruction in patients with symptomatic hardware or repeat rupture: a histologic study in 12 patients

scientific article published in November 2003

Heterotopic implantation of mouse bone-marrow cells: an in vivo model allowing analysis of mineral phases during mineralization processes.

scientific article

Human breast cancer cells educate macrophages toward the M2 activation status

scientific article

Human growth hormone locally released in bone sites by calcium-phosphate biomaterial stimulates ceramic bone substitution without systemic effects: a rabbit study

scientific article published in April 1998

IL-1β and TNFα promote monocyte viability through the induction of GM-CSF expression by rheumatoid arthritis synovial fibroblasts

scientific article published on 17 November 2014

IL-33 is expressed in human osteoblasts, but has no direct effect on bone remodeling

scientific article published on 28 December 2010

IL-34 and M-CSF form a novel heteromeric cytokine and regulate the M-CSF receptor activation and localization.

scientific article

IL-6, RANKL, TNF-alpha/IL-1: interrelations in bone resorption pathophysiology

scientific article published on February 2004

Identification of genomic differences among peripheral arterial beds in atherosclerotic and healthy arteries.

scientific article

Imatinib mesylate exerts anti-proliferative effects on osteosarcoma cells and inhibits the tumour growth in immunocompetent murine models

scientific article (publication date: 2014)

Impact of oncopediatric dosing regimen of zoledronic acid on bone growth: preclinical studies and case report of an osteosarcoma pediatric patient

scientific article published in October 2011

Implication of molecular vascular smooth muscle cell heterogeneity among arterial beds in arterial calcification.

scientific article

In vitro and in vivo discrepancy in inducing apoptosis by mesenchymal stromal cells delivering membrane-bound tumor necrosis factor–related apoptosis inducing ligand in osteosarcoma pre-clinical models

scientific article published in August 2018

Increased levels of leukaemia inhibitory factor (LIF) in urine and tissue culture supernatant from human primary bone tumours

scientific article published in February 1998

Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on oncostatin M signaling

scientific article

Influence of biphasic calcium phosphate granulometry on bone ingrowth, ceramic resorption, and inflammatory reactions: preliminary in vitro and in vivo study

scientific article published in July 1999

Influence of metal ion solutions on rabbit osteoclast activities in vitro

scientific article published in October 2002

Inhibition of BET proteins and epigenetic signaling as a potential treatment for osteoporosis

scientific article published on 23 September 2016

Inhibition of apatite formation by vitronectin

scientific article published in 2000

Inhibition of osteolysis and increase of bone formation after local administration of siRNA-targeting RANK in a polyethylene particle-induced osteolysis model

scientific article published in February 2015

Interaction of Cutibacterium ( formerly Propionibacterium) acnes with bone cells: a step toward understanding bone and joint infection development

scientific article

Interleukin 34 expression is associated with synovitis severity in rheumatoid arthritis patients

scientific article

Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis

scientific article published in May 2010

Interleukin-34 promotes tumor progression and metastatic process in osteosarcoma through induction of angiogenesis and macrophage recruitment

scientific article published on 13 December 2014

Interleukin-6 inhibits receptor activator of nuclear factor kappaB ligand-induced osteoclastogenesis by diverting cells into the macrophage lineage: key role of Serine727 phosphorylation of signal transducer and activator of transcription 3.

scientific article

Jaw osteosarcoma models in mice: first description

Joint bleeding in factor VIII deficient mice causes an acute loss of trabecular bone and calcification of joint soft tissues which is prevented with aggressive factor replacement

scientific article

Key roles of the OPG-RANK-RANKL system in bone oncology

scientific article

Killer dendritic cells link innate and adaptive immunity against established osteosarcoma in rats

scientific article

L-MTP-PE and zoledronic acid combination in osteosarcoma: preclinical evidence of positive therapeutic combination for clinical transfer

scientific article published on 15 February 2016

LPS increases biomaterial degradation by human monocytes in vitro

scientific article published in January 1997

Leukaemia inhibitory factor (LIF) production in pleural effusions: comparison with production of IL-4, IL-8, IL-10 and macrophage-colony stimulating factor (M-CSF)

scientific article published in May 1996

Leukemia inhibitory factor and oncostatin M influence the mineral phases formed in a murine heterotopic calcification model: a Fourier transform-infrared microspectroscopic study

scientific article published in October 1998

Liposomal muramyl tripeptide phosphatidyl ethanolamine: a safe and effective agent against osteosarcoma pulmonary metastases

scientific article

Long term oncostatin M treatment induces an osteocyte-like differentiation on osteosarcoma and calvaria cells

scientific article

Loss of connexin43 expression in Ewing's sarcoma cells favors the development of the primary tumor and the associated bone osteolysis.

scientific article published on 9 January 2013

Loss of miR-198 and -206 during primary tumor progression enables metastatic dissemination in human osteosarcoma

Low-Dose Pesticide Mixture Induces Accelerated Mesenchymal Stem Cell Aging In Vitro

scientific article published on 17 April 2019

Low-Dose Pesticide Mixture Induces Senescence in Normal Mesenchymal Stem Cells (MSC) and Promotes Tumorigenic Phenotype in Premalignant MSC.

scientific article published on 11 November 2016

Maternal RANKL Reduces the Osteopetrotic Phenotype of Null Mutant Mouse Pups

scientific article published on 08 November 2018

Mechanisms of bone repair and regeneration

scientific article published on 08 September 2009

Mechanistic study of the proangiogenic effect of osteoprotegerin

scientific article published on 6 February 2013

Mesenchymal stem cells increase proliferation but do not change quiescent state of osteosarcoma cells: Potential implications according to the tumor resection status

scientific article published on 12 December 2015

Mesenchymal stem cells induce a weak immune response in the rat striatum after allo or xenotransplantation

scientific article published in August 2009

Metastatic osteosarcoma challenged by regorafenib

scientific article published on 23 November 2018

Metatarsal giant cell tumors and giant cell reparative granuloma are similar entities

scientific article published in November 2003

Mifamurtide for the treatment of nonmetastatic osteosarcoma

scientific article published on February 2011

Modulation by soluble factors of gelatinase activities released by osteoblastic cells

scientific article published in November 2000

Modulation of LIF expression in human melanoma cells by oncostatin M

scientific article published in June 1995

Modulatory effects of proteoglycans on proteinase activities

scientific article

Molecular alterations associated with osteosarcoma development

scientific article

Murine Models of Bone Sarcomas

scientific article published on 01 January 2019

NVP-BEZ235, a dual PI3K/mTOR inhibitor, inhibits osteosarcoma cell proliferation and tumor development in vivo with an improved survival rate

scientific article published on 11 December 2013

Novel RANK antagonists for the treatment of bone-resorptive disease: theoretical predictions and experimental validation.

scientific article published in June 2014

Novel anti-cancer strategy in bone tumors by targeting molecular and cellular modulators of bone resorption

scientific article

OPG, RANK and RANK ligand expression in thyroid lesions

scientific article published on 5 June 2008

OPG/membranous--RANKL complex is internalized via the clathrin pathway before a lysosomal and a proteasomal degradation

scientific article published on 5 June 2006

Oncostatin M induces bone loss and sensitizes rat osteosarcoma to the antitumor effect of Midostaurin in vivo

scientific article published on September 2008

Oncostatin M is a growth factor for Ewing sarcoma

scientific article

Oncostatin m, an inflammatory cytokine produced by macrophages, supports intramembranous bone healing in a mouse model of tibia injury

scientific article published in March 2015

Opposite Effects of Soluble Factors Secreted by Adipose Tissue on Proliferating and Quiescent Osteosarcoma Cells

scientific article published on March 2016

Oral administration of edelfosine encapsulated lipid nanoparticles causes regression of lung metastases in pre-clinical models of osteosarcoma

scientific article published in August 2018

Origins of Alterations to Rankl Null Mutant Mouse Dental Root Development

scientific article published on 23 March 2020

Orthopaedic implant failure: aseptic implant loosening--the contribution and future challenges of mouse models in translational research

scientific article published on September 2014

Osteoblastic and osteoclastic differentiation of human mesenchymal stem cells and monocytes in a miniaturized three-dimensional culture with mineral granules.

scientific article

Osteoclastic resorption of biphasic calcium phosphate ceramic in vitro

scientific article published on 5 December 1997

Osteoclastic resorption of calcium phosphate ceramics with different hydroxyapatite/beta-tricalcium phosphate ratios

scientific article published in August 1997

Osteoclasts in RA: diverse origins and functions

scientific article published on 31 May 2013

Osteogenic potential in vitro of human bone marrow cells cultured on macroporous biphasic calcium phosphate ceramic

scientific article published in January 1999

Osteoimmunology of Oral and Maxillofacial Diseases: Translational Applications Based on Biological Mechanisms

scientific article published on 18 July 2019

Osteolytic bone diseases: physiological analogues of bone resorption effectors as alternative therapeutic tools

scientific article

Osteoprotegerin Induces CD34+ Differentiation in Endothelial Progenitor Cells

Osteoprotegerin inhibits bone resorption and prevents tumor development in a xenogenic model of Ewing's sarcoma by inhibiting RANKL

scientific article

Osteoprotegerin regulates cancer cell migration through SDF-1/CXCR4 axis and promotes tumour development by increasing neovascularization

scientific article published on 2 March 2017

Osteoprotegerin, a new actor in vasculogenesis, stimulates endothelial colony-forming cells properties.

scientific article

Osteoprotegerin, pericytes and bone-like vascular calcification are associated with carotid plaque stability

scientific article

Osteoprotegerin: a new therapeutic agent for the treatment of bone disease

scientific article published in December 2001

Osteoprotegerin: multiple partners for multiple functions

scientific article published on July 2013

Osteosarcoma: current status of immunotherapy and future trends (Review).

scientific article

Overexpression of smad7 blocks primary tumor growth and lung metastasis development in osteosarcoma

scientific article

Oxytocin reverses osteoporosis in a sex-dependent manner

scientific article published on 19 May 2015

Oxytocin reverses ovariectomy-induced osteopenia and body fat gain.

scientific article published on 7 February 2014

Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice

scientific article published on 29 May 2019

Paradoxical side effects of bisphosphonates on the skeleton: what do we know and what can we do?

scientific article published on 11 January 2018

Pathogenic potential of Escherichia coli clinical strains from orthopedic implant infections towards human osteoblastic cells

scientific article published on September 2015

Pericyte-like progenitors show high immaturity and engraftment potential as compared with mesenchymal stem cells.

scientific article

Pharmacodynamics of bisphosphonates in arthritis

scientific article published on September 2011

Pharmacological blocking of the osteoclastic biocorrosion of surgical stainless steel in vitro

scientific article published on 10 September 2012

Phenotypic and functional analysis of lymphocytes infiltrating osteolytic tumors: use as a possible therapeutic approach of osteosarcoma

scientific article

Polymyxin B inhibits biphasic calcium phosphate degradation induced by lipopolysaccharide-activated human monocytes/macrophages

scientific article published in May 1998

Potential synergies between matrix proteins and soluble factors on resorption and proteinase activities of rabbit bone cells.

scientific article published in July 2001

Pre-clinical studies of bone regeneration with human bone marrow stromal cells and biphasic calcium phosphate

scientific article published on 13 October 2014

Preclinical evidence of potential craniofacial adverse effect of zoledronic acid in pediatric patients with bone malignancies

scientific article published in November 2014

Preclinical evidence that use of TRAIL in Ewing's sarcoma and osteosarcoma therapy inhibits tumor growth, prevents osteolysis, and increases animal survival

scientific article published on 6 April 2010

Presence of leukaemia inhibitory factor (LIF) and LIF-receptor chain (gp190) in osteoclast-like cells cultured from human giant cell tumour of bone. Ultrastructural distribution

scientific article published in April 1999

Primary Retention of Molars and RANKL Signaling Alteration during Craniofacial Growth

scientific article published on 25 March 2020

Pro-osteoclastic in vitro effect of Polyethylene-like nanoparticles: Involvement in the pathogenesis of implant aseptic loosening

scientific article published on 2 June 2016

Proteases and bone remodelling

scientific article

Proteoglycans and osteolysis

scientific article

Proteoglycans on bone tumor development

scientific article published on 27 May 2010

Proteoglycans: key partners in bone cell biology

scientific article published on August 2007

RANK-RANKL signalling in cancer

scientific article

RANKL directly induces bone morphogenetic protein-2 expression in RANK-expressing POS-1 osteosarcoma cells.

scientific article published on January 2006

RANKL, RANK, osteoprotegerin: key partners of osteoimmunology and vascular diseases

scientific article

RANKL/RANK/OPG: key therapeutic target in bone oncology

scientific article published on September 2008

RANKL/RANK/OPG: new therapeutic targets in bone tumours and associated osteolysis

scientific article published in September 2004

Radiotherapy-induced overexpression of exosomal miRNA-378a-3p in cancer cells limits natural killer cells cytotoxicity

scientific article published on 08 April 2020

Recent advances in TGF-beta effects on chondrocyte metabolism. Potential therapeutic roles of TGF-beta in cartilage disorders.

scientific article

Receptor activator of nuclear factor kappaB ligand (RANKL)/osteoprotegerin (OPG) ratio is increased in severe osteolysis

scientific article published in November 2003

Receptor activator of nuclear factor-kappa B ligand (RANKL) stimulates bone-associated tumors through functional RANK expressed on bone-associated cancer cells?

scientific article published on February 2009

Receptor activator of nuclear factor-kappaB ligand (RANKL) directly modulates the gene expression profile of RANK-positive Saos-2 human osteosarcoma cells.

scientific article published on December 2007

Receptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancers

scientific article

Regulation and function of immunosuppressive molecule human leukocyte antigen G5 in human bone tissue

scientific article published on 16 April 2013

Regulation of osteoclast protease expression by RANKL.

scientific article published in October 2003

Relevance of a new rat model of osteoblastic metastases from prostate carcinoma for preclinical studies using zoledronic acid

scientific article published in February 2008

Relevance of an in vitro osteoclastogenesis system to study receptor activator of NF-kB ligand and osteoprotegerin biological activities

scientific article published on February 2004

Relevance of the POS-1 orthotopic model as an "imaging model" for in vivo and simultaneous monitoring of tumor proliferation and bone remodeling in osteosarcoma

scientific article published in February 2012

Report from the 4th European Bone Sarcoma Networking meeting: focus on osteosarcoma

Role for interleukin-6 in structural joint damage and systemic bone loss in rheumatoid arthritis

scientific article published on 04 May 2010

Role of the OPG/RANK/RANKL triad in calcifications of the atheromatous plaques: comparison between carotid and femoral beds.

scientific article

Safety concern between autologous fat graft, mesenchymal stem cell and osteosarcoma recurrence

scientific article

Sarcoma treatment in the era of molecular medicine

scientific article published on 13 October 2020

Scanning electron microscopic description of cellular activity and mineral changes in feline odontoclastic resorptive lesions.

scientific article published in December 2001

Selective inhibition of BET bromodomain epigenetic signalling interferes with the bone-associated tumour vicious cycle

scientific article published on 19 March 2014

Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw

scientific article published in September 2016

Sex-specific autophagy modulation in osteoblastic lineage: a critical function to counteract bone loss in female

scientific article published on 13 September 2016

Skeletal consequences of RANKL-blocking antibody (IK22-5) injections during growth: Mouse strain disparities and synergic effect with zoledronic acid

scientific article published in April 2015

Small animal models for the study of bone sarcoma pathogenesis:characteristics, therapeutic interests and limitations.

scientific article published on 21 February 2018

Syndecan-1 regulates the biological activities of interleukin-34.

scientific article

Syndromic surveillance: two decades experience of sustainable systems - its people not just data!

article

Synergistic inhibitory effect of apomine and lovastatin on osteosarcoma cell growth.

scientific article published on 12 July 2011

TH1579, MTH1 inhibitor, delays tumour growth and inhibits metastases development in osteosarcoma model

scientific article published on 07 March 2020

TRAIL delivered by mesenchymal stromal/stem cells counteracts tumor development in orthotopic Ewing sarcoma models

scientific article published on 25 August 2016

TRAIL receptor signaling and therapeutic option in bone tumors: the trap of the bone microenvironment.

scientific article published on 09 October 2011

TRAIL-based therapy in pediatric bone tumors: how to overcome resistance

scientific article

Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1.

scientific article published on 19 March 2016

The Challenges of Detecting Circulating Tumor Cells in Sarcoma

scientific article

The Intrinsic and Extrinsic Implications of RANKL/RANK Signaling in Osteosarcoma: From Tumor Initiation to Lung Metastases

article

The Release of Inflammatory Mediators from Acid-Stimulated Mesenchymal Stromal Cells Favours Tumour Invasiveness and Metastasis in Osteosarcoma

scientific article published in 2021

The contribution of immune infiltrates and the local microenvironment in the pathogenesis of osteosarcoma

scientific article published on 2 November 2017

The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling

scientific article

The twin cytokines interleukin-34 and CSF-1: masterful conductors of macrophage homeostasis

scientific article published on 01 January 2021

The vertebral interbody grafting site's low concentration in osteogenic progenitors can greatly benefit from addition of iliac crest bone marrow

scientific article

Therapeutic efficacy of soluble receptor activator of nuclear factor-kappa B-Fc delivered by nonviral gene transfer in a mouse model of osteolytic osteosarcoma

scientific article published on October 2008

Therapeutic relevance of osteoprotegerin gene therapy in osteosarcoma: blockade of the vicious cycle between tumor cell proliferation and bone resorption

scientific article published in August 2007

Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer

scientific article published on 01 May 2022

Tumour Heterogeneity: The Key Advantages of Single-Cell Analysis

scientific article

Ultrastructural evidence in vitro of osteoclast-induced degradation of calcium phosphate ceramic by simultaneous resorption and phagocytosis mechanisms

scientific article published in January 2001

Upmodulation of alpha v beta 1 integrin expression on human tumor cells by human interleukin for DA cells/leukemia inhibitory factor and oncostatin M: correlation with increased cell adhesion on fibronectin.

scientific article

Upmodulation of multinucleated cell formation in long-term human bone marrow cultures by leukaemia inhibitory factor (LIF)

scientific article published in January 1997

Zebrafish xenograft models of cancer and metastasis for drug discovery.

scientific article published on March 2017

Zoledronic acid activates the DNA S-phase checkpoint and induces osteosarcoma cell death characterized by apoptosis-inducing factor and endonuclease-G translocation independently of p53 and retinoblastoma status

scientific article published on 18 October 2006

Zoledronic acid as a new adjuvant therapeutic strategy for Ewing's sarcoma patients

scientific article published on 14 September 2010

Zoledronic acid inhibits pulmonary metastasis dissemination in a preclinical model of Ewing's sarcoma via inhibition of cell migration

scientific article

Zoledronic acid slows down rat primary chondrosarcoma development, recurrent tumor progression after intralesional curretage and increases overall survival.

scientific article

Zoledronic acid suppresses lung metastases and prolongs overall survival of osteosarcoma-bearing mice

scientific article published on December 2005

[Excimer laser-assisted lamellar endothelial keratoplasty (ExALEK): Technique and results].

scientific article published on 27 January 2016

[In vitro assessment of combining osteogenic cells with macroporous calcium-phosphate ceramics]

scientific article published in February 2001

[Modulation of integrin alpha-v-beta-1 expression on human tumor cells by leukemia inhibitory factor (LIF) and oncostatin M (OSM)]

scientific article published in January 1996

mAbs targeting RANKL in bone metastasis treatment

scientific article published in April 2013

mTOR inhibitors (rapamycin and its derivatives) and nitrogen containing bisphosphonates: bi-functional compounds for the treatment of bone tumours

scientific article published on January 2007

miRNA-193a-5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors

scientific article published on 29 July 2016

ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis

scientific article published on 17 March 2016

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