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List of works by Rickie Patani

A Liquid to Solid Phase Transition Underlying Pathological Huntingtin Exon1 Aggregation.

scientific article

A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models

scientific article published on 27 October 2017

Abnormal tau phosphorylation in primary progressive multiple sclerosis

scientific article published on 21 March 2010

Abnormally phosphorylated tau is associated with neuronal and axonal loss in experimental autoimmune encephalomyelitis and multiple sclerosis

scientific article published on 21 June 2008

Activin/Nodal inhibition alone accelerates highly efficient neural conversion from human embryonic stem cells and imposes a caudal positional identity

scientific article

Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study

scientific article published on 10 January 2012

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.

scientific article published on 27 February 2011

Chloroquine, the Coronavirus Crisis, and Neurodegeneration: A Perspective

scientific article published on 13 November 2020

Concise Review: The Cellular Conspiracy of Amyotrophic Lateral Sclerosis

scientific article published on 13 December 2017

Dopamine from the brain promotes spinal motor neuron generation during development and adult regeneration.

scientific article published on 23 May 2013

Elucidating Pro-Inflammatory Cytokine Responses after Traumatic Brain Injury in a Human Stem Cell Model

scientific article published on 5 October 2017

Evidence for abnormal tau phosphorylation in early aggressive multiple sclerosis

scientific article published on 14 March 2009

Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons

scientific article published on October 2016

Experimental and therapeutic opportunities for stem cells in multiple sclerosis

scientific article

FUS is lost from nuclei and gained in neurites of motor neurons in a human stem cell model of VCP-related ALS

scientific article published on 30 November 2020

Flexor hallucis brevis spasm

scientific article published on 26 March 2013

G-quadruplex-binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo.

scientific article published on 7 November 2017

Generating Diverse Spinal Motor Neuron Subtypes from Human Pluripotent Stem Cells

scientific article

Harnessing cellular aging in human stem cell models of amyotrophic lateral sclerosis

scientific article published on 19 December 2018

Human Stem Cell-Derived Astrocytes: Specification and Relevance for Neurological Disorders

scientific article

Human embryonic stem cell derived astrocytes mediate non-cell-autonomous neuroprotection through endogenous and drug-induced mechanisms.

scientific article

Human embryonic stem cell-derived neurons as a tool for studying neuroprotection and neurodegeneration

scientific article

Human stem cell-derived astrocytes exhibit region-specific heterogeneity in their secretory profiles

scientific article published on 08 September 2020

Human stem cell-derived neurons: a system to study human tau function and dysfunction

scientific article

Hypothermic Preconditioning Reverses Tau Ontogenesis in Human Cortical Neurons and is Mimicked by Protein Phosphatase 2A Inhibition

scientific article published on 12 December 2015

Hypothermic Preconditioning of Human Cortical Neurons Requires Proteostatic Priming

scientific article

Image‐based deep learning reveals the responses of human motor neurons to stress and <i>VCP</i>‐related ALS

scientific article published in 2021

In vitro prion-like behaviour of TDP-43 in ALS.

scientific article published on 30 August 2016

Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling

scientific article published on April 2011

Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS.

scientific article published on 22 May 2018

Investigating the utility of human embryonic stem cell-derived neurons to model ageing and neurodegenerative disease using whole-genome gene expression and splicing analysis

scientific article published on 10 July 2012

Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength.

scientific article published on 5 April 2018

Lymphomatosis cerebri: a treatable cause of rapidly progressive dementia

scientific article published on 20 May 2014

MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration

scientific article published on 19 May 2021

Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

scientific article published on January 2017

Meta-analysis of human and mouse ALS astrocytes reveals multi-omic signatures of inflammatory reactive states

scientific article published on 28 December 2021

Mild oxidative stress activates Nrf2 in astrocytes, which contributes to neuroprotective ischemic preconditioning.

scientific article published on 21 December 2010

Neural Conversion and Patterning of Human Pluripotent Stem Cells: A Developmental Perspective

scientific article

Paraspeckle components NONO and PSPC1 are not mislocalized from motor neuron nuclei in sporadic ALS

scientific article published on 01 August 2020

Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS

scientific article

Quo vadis motor neuron disease?

scientific article

Reactive astrocytes in ALS display diminished intron retention

scientific article published on 01 April 2021

Regionally encoded functional heterogeneity of astrocytes in health and disease: A perspective

scientific article published on 17 June 2020

Retinoid-independent motor neurogenesis from human embryonic stem cells reveals a medial columnar ground state

scientific article

Stem cells as a resource for regenerative neurology

scientific article published on February 2011

Stress-Specific Spatiotemporal Responses of RNA-Binding Proteins in Human Stem-Cell-Derived Motor Neurons

scientific article published on 06 November 2020

TS or not TS?

scientific article published on 13 March 2013

The FUS about SFPQ in FTLD spectrum disorders

scientific article published on 01 August 2020

The FUS gene is dual-coding with both proteins contributing to FUS-mediated toxicity

scientific article published on 23 November 2020

The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open-label pre-test: post-test study with blinded outcome assessments

scientific article

The translational potential of human induced pluripotent stem cells for clinical neurology : The translational potential of hiPSCs in neurology

scientific article published on 03 December 2016

Three-Dimensional Human iPSC-Derived Artificial Skeletal Muscles Model Muscular Dystrophies and Enable Multilineage Tissue Engineering.

scientific article published in April 2018

Unsupervised Cell Segmentation and Labelling in Neural Tissue Images

scientific article published on 21 April 2021

Using human induced pluripotent stem cells to model cerebellar disease: hope and hype.

scientific article

Using human pluripotent stem cells to study post-transcriptional mechanisms of neurodegenerative diseases

scientific article published on 05 January 2012

Using induced pluripotent stem cells (iPSC) to model human neuromuscular connectivity: promise or reality?

scientific article published on 02 December 2011

Voltage-gated potassium channelopathy: an expanding spectrum of clinical phenotypes

scientific article published on January 10, 2013

Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis

scientific article published on 01 September 2019