List of works - Andrew Billin

A 13-amino acid amphipathic alpha-helix is required for the functional interaction between the transcriptional repressor Mad1 and mSin3A

scientific article published on 01 November 1999

A Fibrosis-Independent Hepatic Transcriptomic Signature Identifies Novel Drivers of Disease Progression in Primary Sclerosing Cholangitis

scientific article published on 03 August 2020

A new, highly selective murine peroxisome proliferator-activated receptor δ agonist increases responsiveness to thermogenic stimuli and glucose uptake in skeletal muscle in obese mice ⬇️

scientific article published on January 27, 2011

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

scientific article (publication date: 31 May 2011)

Co-crystal structure guided array synthesis of PPARgamma inverse agonists

scientific article

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

scientific article

Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle.

scientific article published on 22 December 2015

Discovery of a novel class of PPARdelta partial agonists

scientific article

ERRgamma regulates cardiac, gastric, and renal potassium homeostasis

scientific article

Expression profiling of peroxisome proliferator-activated receptor-delta (PPAR-delta) in mouse tissues using tissue microarray

scientific article published on 02 March 2007

Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility

scientific article published on 19 August 2015

Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression

scholarly article

Helix 1/8 interactions influence the activity of nuclear receptor ligand-binding domains.

scientific article published on 19 June 2003

Hematopoietic, CNS And Skeletal Muscle Stem Cells As Drug Targets: Opportunities, Progress And Challenges ⬇️

scientific article published on April 1, 2012

Histone deacetylase activity is required for full transcriptional repression by mSin3A

scientific article (publication date: 2 May 1997)

Human and mouse skeletal muscle stem cells: convergent and divergent mechanisms of myogenesis.

scientific article

Identification and characterization of a selective peroxisome proliferator-activated receptor beta/delta (NR1C2) antagonist.

scientific article published on November 2007

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes

scientific article (publication date: 9 May 2003)

Isolation of a family of Drosophila POU domain genes expressed in early development ⬇️

scientific article published on June 1, 1991

Lack of evidence for GDF11 as a rejuvenator of aged skeletal muscle satellite cells.

scientific article published on 28 March 2016

Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.

scientific article

Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms.

scientific article published on 24 September 2007

Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes

scientific article published on 3 January 2007

Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells.

scientific article

Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors

scientific article

Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARbeta/delta ligand GW0742.

scientific article

MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network

scientific article

PPAR-β/δ agonists for Type 2 diabetes and dyslipidemia: an adopted orphan still looking for a home

article by Andrew Billin published 22 September 2008 in Expert Opinion on Investigational Drugs

PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.

scientific article published on 3 April 2007

PPARbeta/delta selectively induces differentiation and inhibits cell proliferation

scientific article published in January 2006

Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines.

scientific article published on 4 November 2007

Phenoxyacetic acids as PPARδ partial agonists: synthesis, optimization, and in vivo efficacy

scientific article

Post-transcriptional regulation of ITGB6 protein levels in damaged skeletal muscle

scientific article published on 2 February 2014

Regulation of expression domains and effects of ectopic expression reveal gap gene-like properties of the linked pdm genes of Drosophila

scientific article

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

scientific article

SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors

scientific article

Satellite cell therapy - from mice to men

scientific article published on 31 January 2013

Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3

scientific article (publication date: July 2011)

Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity

scientific article

The Mlx network: evidence for a parallel Max-like transcriptional network that regulates energy metabolism.

scientific article

The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS-9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis

scientific article published on 10 March 2019

The Nop60B gene of Drosophila encodes an essential nucleolar protein that functions in yeast

scientific article

The next generation of PPAR drugs: do we have the tools to find them?

scientific article published on 2 June 2007

Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist.

scientific article

List of works by Andrew Billin

A 13-amino acid amphipathic alpha-helix is required for the functional interaction between the transcriptional repressor Mad1 and mSin3A

A Fibrosis-Independent Hepatic Transcriptomic Signature Identifies Novel Drivers of Disease Progression in Primary Sclerosing Cholangitis

A new, highly selective murine peroxisome proliferator-activated receptor δ agonist increases responsiveness to thermogenic stimuli and glucose uptake in skeletal muscle in obese mice ⬇️

Bromodomain protein Brd3 associates with acetylated GATA1 to promote its chromatin occupancy at erythroid target genes

Co-crystal structure guided array synthesis of PPARgamma inverse agonists

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis

Discovery of Novel Small Molecules that Activate Satellite Cell Proliferation and Enhance Repair of Damaged Muscle.

Discovery of a novel class of PPARdelta partial agonists

ERRgamma regulates cardiac, gastric, and renal potassium homeostasis

Expression profiling of peroxisome proliferator-activated receptor-delta (PPAR-delta) in mouse tissues using tissue microarray

Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility

Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression

Helix 1/8 interactions influence the activity of nuclear receptor ligand-binding domains.

Hematopoietic, CNS And Skeletal Muscle Stem Cells As Drug Targets: Opportunities, Progress And Challenges ⬇️

Histone deacetylase activity is required for full transcriptional repression by mSin3A

Human and mouse skeletal muscle stem cells: convergent and divergent mechanisms of myogenesis.

Identification and characterization of a selective peroxisome proliferator-activated receptor beta/delta (NR1C2) antagonist.

Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes

Isolation of a family of Drosophila POU domain genes expressed in early development ⬇️

Lack of evidence for GDF11 as a rejuvenator of aged skeletal muscle satellite cells.

Ligand activation of peroxisome proliferator-activated receptor beta inhibits colon carcinogenesis.

Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) attenuate colon carcinogenesis through independent signaling mechanisms.

Ligand activation of peroxisome proliferator-activated receptor-beta/delta(PPARbeta/delta) inhibits cell growth of human N/TERT-1 keratinocytes

Mechano-growth factor peptide, the COOH terminus of unprocessed insulin-like growth factor 1, has no apparent effect on myoblasts or primary muscle stem cells.

Mlx, a novel Max-like BHLHZip protein that interacts with the Max network of transcription factors

Modulation of LPS-induced pulmonary neutrophil infiltration and cytokine production by the selective PPARbeta/delta ligand GW0742.

MondoA, a novel basic helix-loop-helix-leucine zipper transcriptional activator that constitutes a positive branch of a max-like network

PPAR-β/δ agonists for Type 2 diabetes and dyslipidemia: an adopted orphan still looking for a home

PPARbeta/delta protects against experimental colitis through a ligand-independent mechanism.

PPARbeta/delta selectively induces differentiation and inhibits cell proliferation

Peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) ligands inhibit growth of UACC903 and MCF7 human cancer cell lines.

Phenoxyacetic acids as PPARδ partial agonists: synthesis, optimization, and in vivo efficacy

Post-transcriptional regulation of ITGB6 protein levels in damaged skeletal muscle

Regulation of expression domains and effects of ectopic expression reveal gap gene-like properties of the linked pdm genes of Drosophila

Rhabdomyosarcoma: current challenges and their implications for developing therapies.

SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors

Satellite cell therapy - from mice to men

Structural basis and specificity of acetylated transcription factor GATA1 recognition by BET family bromodomain protein Brd3

Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity

The Mlx network: evidence for a parallel Max-like transcriptional network that regulates energy metabolism.

The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS-9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis

The Nop60B gene of Drosophila encodes an essential nucleolar protein that functions in yeast

The next generation of PPAR drugs: do we have the tools to find them?

Triglyceride:high-density lipoprotein cholesterol effects in healthy subjects administered a peroxisome proliferator activated receptor delta agonist.