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List of works by James Olzmann

A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation

scientific article published on 10 March 2020

A Proteomic Map to Navigate Subcellular Reorganization in Fatty Liver Disease

scientific article published on 01 October 2018

A Proximity Labeling Strategy Provides Insights into the Composition and Dynamics of Lipid Droplet Proteomes.

scientific article published on 19 December 2017

A Tense Situation: Maintaining ER Homeostasis during Lipid Droplet Budding

scientific article published on 01 July 2019

A VCP inhibitor substrate trapping approach (VISTA) enables proteomic profiling of endogenous ERAD substrates

scientific article published on 7 March 2018

A polyubiquitin chain reaction: parkin recruitment to damaged mitochondria

scientific article published on 22 January 2015

Aggresome formation and neurodegenerative diseases: therapeutic implications

scientific article

Characterization of protein complexes of the endoplasmic reticulum-associated degradation E3 ubiquitin ligase Hrd1.

scientific article published on 14 April 2017

Chemoproteomics-Enabled Covalent Ligand Screening Reveals a Thioredoxin-Caspase 3 Interaction Disruptor That Impairs Breast Cancer Pathogenicity

scientific article published on 11 September 2017

Chemoproteomics-enabled covalent ligand screen reveals a cysteine hotspot in reticulon 4 that impairs ER morphology and cancer pathogenicity

scientific article published on 29 March 2017

Corneal dystrophy-associated R124H mutation disrupts TGFBI interaction with Periostin and causes mislocalization to the lysosome

scientific article

Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition

scientific article published on 08 July 2019

DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy

scientific article published on July 2017

Defining human ERAD networks through an integrative mapping strategy

scientific article

Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum

scientific article

Dynamics and functions of lipid droplets

scientific article published on 01 March 2019

Endoplasmic Reticulum-Associated Degradation and Lipid Homeostasis

scientific article published on 26 May 2016

Establishing the lipid droplet proteome: Mechanisms of lipid droplet protein targeting and degradation

scientific article

Exogenous Monounsaturated Fatty Acids Promote a Ferroptosis-Resistant Cell State

scientific article published on 24 January 2019

Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function

scientific article

Getting a handle on lipid droplets: Insights into ER-lipid droplet tethering

scientific article published on 18 March 2019

Going through a phase

scientific article published on 01 February 2020

Harnessing the anti-cancer natural product nimbolide for targeted protein degradation

scientific article published on 17 June 2019

High glucose-induced oxidative stress and mitochondrial dysfunction in neurons.

scientific article published in November 2002

Identification of Lipid Droplet Proteomes by Proximity Labeling Proteomics Using APEX2

scientific article published on 01 January 2019

In Close Proximity: The Lipid Droplet Proteome and Crosstalk With the Endoplasmic Reticulum

scientific article published on 01 January 2018

Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation

scientific article

Lipid droplet formation is dispensable for endoplasmic reticulum-associated degradation

scientific article

Lipid droplets and lipotoxicity during autophagy

scientific article published on 14 August 2017

Making the cut: intramembrane cleavage by a rhomboid protease promotes ERAD.

scientific article published on October 2012

Mutations associated with Charcot-Marie-Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome-autophagy pathways

scientific article

Optimized protocol for the identification of lipid droplet proteomes using proximity labeling proteomics in cultured human cells

scientific article published on 05 June 2021

Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases

scientific article

PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1

scientific article

Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6

scientific article

Parkin-mediated K63-linked polyubiquitination: a signal for targeting misfolded proteins to the aggresome-autophagy pathway.

scientific article published on 15 October 2007

Parkin-mediated ubiquitin signalling in aggresome formation and autophagy

scientific article

Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells

scientific article published on 09 May 2019

SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells.

scientific article published on 12 September 2009

Selective enrichment of DJ-1 protein in primate striatal neuronal processes: implications for Parkinson's disease

scientific article published on January 2007

Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover

scientific article

Spongiform neurodegeneration-associated E3 ligase Mahogunin ubiquitylates TSG101 and regulates endosomal trafficking

scientific article

The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis

scientific article published on 21 October 2019

The Lipid Droplet Knowledge Portal: A resource for systematic analyses of lipid droplet biology

scientific article published on 01 February 2022

Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate

scientific article

Uncoupling proteins prevent glucose-induced neuronal oxidative stress and programmed cell death

scientific article published in March 2004