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List of works by Jane Freeman

A five year outbreak of methicillin-susceptible Staphylococcus aureus phage type 53,85 in a regional neonatal unit ⬇️

scientific article published in February 2000

Activity of vancomycin against epidemic Clostridium difficile strains in a human gut model

scientific article

Antibiotic activity against genotypically distinct and indistinguishable Clostridium difficile isolates

scientific article published on 01 February 2001

Antibiotics and Clostridium difficile

scientific article

Co-amoxiclav induces proliferation and cytotoxin production of Clostridium difficile ribotype 027 in a human gut model

scientific article published on 25 January 2012

Comparison of oritavancin versus vancomycin as treatments for clindamycin-induced Clostridium difficile PCR ribotype 027 infection in a human gut model

scientific article published on 4 September 2008

Comparison of planktonic and biofilm-associated communities of Clostridium difficile and indigenous gut microbiota in a triple-stage chemostat gut model

scientific article

Comparison of the effect of detergent versus hypochlorite cleaning on environmental contamination and incidence of Clostridium difficile infection

scientific article

Comparison of the efficacy of ramoplanin and vancomycin in both in vitro and in vivo models of clindamycin-induced Clostridium difficile infection

scientific article

Complete Genome Sequence of the Hypervirulent Bacterium Clostridium difficile Strain G46, Ribotype 027.

scientific article published on 26 March 2015

Development and validation of a chemostat gut model to study both planktonic and biofilm modes of growth of Clostridium difficile and human microbiota ⬇️

scientific article

Effect of metronidazole on growth and toxin production by epidemic Clostridium difficile PCR ribotypes 001 and 027 in a human gut model

scientific article published on 5 May 2007

Effectiveness of a short (4 day) course of oritavancin in the treatment of simulated Clostridium difficile infection using a human gut model

scientific article published on 21 June 2012

Effects of cefotaxime and desacetylcefotaxime upon Clostridium difficile proliferation and toxin production in a triple-stage chemostat model of the human gut.

scientific article published on 29 May 2003

Effects of control interventions on Clostridium difficile infection in England: an observational study ⬇️

scientific article published on 24 January 2017

Effects of exposure of Clostridium difficile PCR ribotypes 027 and 001 to fluoroquinolones in a human gut model

scientific article published on 18 August 2008

Effects of piperacillin/tazobactam on Clostridium difficile growth and toxin production in a human gut model

scientific article published on 28 April 2005

Efficacy of hospital cleaning agents and germicides against epidemic Clostridium difficile strains

scientific article published on 15 June 2007

Efficacy of surotomycin in an in vitro gut model of Clostridium difficile infection

scientific article published on 9 May 2014

Emergence of reduced susceptibility to metronidazole in Clostridium difficile

scientific article

Epidemic Clostridium difficile

Evaluation of NVB302 versus vancomycin activity in an in vitro human gut model of Clostridium difficile infection

scientific article

Evaluation of antimicrobial activity of ceftaroline against Clostridium difficile and propensity to induce C. difficile infection in an in vitro human gut model

scientific article published on 3 April 2013

Evaluation of linezolid for the treatment of Clostridium difficile infection caused by epidemic strains using an in vitro human gut model

scientific article published on 18 April 2011

Evaluation of the effect of oritavancin on Clostridium difficile spore germination, outgrowth and recovery

scientific article published on 11 June 2013

Evidence to support the existence of subgroups within the UK epidemic Clostridium difficile strain (PCR ribotype 1).

scientific article published in May 2003

In Vitro Activities of MCB3681 and Eight Comparators against Clostridium difficile Isolates with Known Ribotypes and Diverse Geographical Spread ⬇️

scientific article published on 19 December 2016

In vitro activity of cadazolid against clinically relevant Clostridium difficile isolates and in an in vitro gut model of C. difficile infection

scientific article published on 14 October 2013

In vitro activity of new generation fluoroquinolones against genotypically distinct and indistinguishable Clostridium difficile isolates

scientific article published on 01 October 2000

In vitro susceptibility of Clostridium difficile to SMT19969 and comparators, as well as the killing kinetics and post-antibiotic effects of SMT19969 and comparators against C. difficile ⬇️

scientific article published on 3 February 2015

In vitro susceptibility of genotypically distinct and clonal Clostridium difficile strains to oritavancin

scientific article published on 7 July 2008

Increased rate of DNA recovery from United Kingdom epidemic Clostridium difficile PCR ribotype 1 strains stored cryogenically

scientific article

Investigating the effect of supplementation on Clostridium difficile spore recovery in two solid agars ⬇️

scientific article published on 31 January 2018

Long-term surveillance of cefotaxime and piperacillin-tazobactam prescribing and incidence of Clostridium difficile diarrhoea

scientific article published on 26 May 2004

Measurement of toxin production by Clostridium difficile

scientific article published in The Lancet

Mecillinam: a low-risk antimicrobial agent for induction of Clostridium difficile infection in an in vitro human gut model

scientific article published on 11 February 2009

Microbiological factors affecting Clostridium difficile recurrence ⬇️

scientific article published on 2 December 2017

Mixed infection by Clostridium difficile in an in vitro model of the human gut

article

Models for the study of Clostridium difficile infection

scientific article

Molecular epidemiology of endemic Clostridium difficile infection and the significance of subtypes of the United Kingdom epidemic strain (PCR ribotype 1)

scientific article

Nitazoxanide is active against Clostridium difficile strains with reduced susceptibility to metronidazole

scientific article published in 2011

Oritavancin does not induce Clostridium difficile germination and toxin production in hamsters or a human gut model

scientific article published on 16 August 2012

Pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes

scientific article published on 13 October 2014

Predictive values of models of Clostridium difficile infection

scientific article published on 09 January 2015

Recurrence of dual-strain Clostridium difficile infection in an in vitro human gut model ⬇️

scientific article published on 29 April 2015

Reduced susceptibility of Clostridium difficile to metronidazole.

scientific article

Role of cephalosporins in the era of Clostridium difficile infection ⬇️

scientific article

SMT19969 as a treatment for Clostridium difficile infection: an assessment of antimicrobial activity using conventional susceptibility testing and an in vitro gut model ⬇️

scientific article published on 3 September 2014

Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease ⬇️

scientific article (publication date: 2013)

Successful treatment of simulated Clostridium difficile infection in a human gut model by fidaxomicin first line and after vancomycin or metronidazole failure

scientific article published on 3 September 2013

Surveillance for resistance to metronidazole and vancomycin in genotypically distinct and UK epidemic Clostridium difficile isolates in a large teaching hospital

scientific article

Susceptibility of Clostridium difficile Isolates of Varying Antimicrobial Resistance Phenotypes to SMT19969 and 11 Comparators ⬇️

scientific article

The ClosER study: results from a three-year pan-European longitudinal surveillance of antibiotic resistance among prevalent Clostridium difficile ribotypes, 2011-2014. ⬇️

scientific article published on 21 October 2017

The changing epidemiology of Clostridium difficile infections

scientific article (publication date: July 2010)

The effects of storage conditions on viability of Clostridium difficile vegetative cells and spores and toxin activity in human faeces ⬇️

scientific article published in February 2003

Tigecycline does not induce proliferation or cytotoxin production by epidemic Clostridium difficile strains in a human gut model

scientific article published on 8 October 2006

Tolevamer is not efficacious in the neutralization of cytotoxin in a human gut model of Clostridium difficile infection

scientific article published on 17 February 2009

Update on Clostridium difficile from the European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Vienna, Austria, April 22-25, 2017.

scientific article published in December 2017

Use of highly discriminatory fingerprinting to analyze clusters of Clostridium difficile infection cases due to epidemic ribotype 027 strains

scientific article published on 23 January 2008

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