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List of works by Yves Lepelletier

A RasGAP SH3 peptide aptamer inhibits RasGAP-Aurora interaction and induces caspase-independent tumor cell death

scientific article

A Subset of Human Dendritic Cells Expresses IgA Fc Receptor (CD89), Which Mediates Internalization and Activation Upon Cross-Linking by IgA Complexes

scientific article published on 01 January 2001

A neuronal receptor, neuropilin-1, is essential for the initiation of the primary immune response

article

A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients

scientific article published on 30 October 2003

A neutralizing monoclonal antibody (mAb A24) directed against the transferrin receptor induces apoptosis of tumor T lymphocytes from ATL patients

APN/CD13 is over-expressed by Psoriatic fibroblasts and is modulated by CGRP and IL-4 but not by retinoic acid treatment

scientific article

Apoptosis-induced proteinase 3 membrane expression is independent from degranulation

scientific article published on 2 October 2003

Arsenic/interferon specifically reverses 2 distinct gene networks critical for the survival of HTLV-1-infected leukemic cells

scientific article

Blood CD34-c-Kit+ cell rate correlates with aggressive forms of systemic mastocytosis and behaves like a mast cell precursor

scientific article published on 30 August 2011

Common variable immunodeficiency is associated with defective functions of dendritic cells

scientific article

Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.

scientific article published on 22 May 2005

Control of human thymocyte migration by Neuropilin-1/Semaphorin-3A-mediated interactions

scholarly article

Current concepts and treatment advances in systemic mastocytosis

scientific article published on 10 April 2008

Current concepts regarding the HTLV-1 receptor complex

scientific article

DOR-1, A novel CD10+ stromal cell line derived from progressive Langerhans cell histiocytosis of bone.

scientific article published on February 2005

Depletion of the novel protein PHACTR-1 from human endothelial cells abolishes tube formation and induces cell death receptor apoptosis

scientific article

Deregulation of microRNA involved in hematopoiesis and the immune response in HTLV-I adult T-cell leukemia

scientific article published on 26 February 2009

Differential expression and function of IgA receptors (CD89 and CD71) during maturation of dendritic cells

scientific article published on 15 September 2004

Differentiation of Langerhans cells in Langerhans cell histiocytosis

scientific article published on 01 March 2001

Disruption of phactr-1 pathway triggers pro-inflammatory and pro-atherogenic factors: New insights in atherosclerosis development.

scientific article published on 9 September 2015

Does Cysteine Rule (CysR) Complete the CendR Principle? Increase in Affinity of Peptide Ligands for NRP-1 Through the Presence of N-Terminal Cysteine

scientific article published on 13 March 2020

EAPB0203, a member of the imidazoquinoxaline family, inhibits growth and induces caspase-dependent apoptosis in T-cell lymphomas and HTLV-I-associated adult T-cell leukemia/lymphoma

scientific article

Efficacy and mechanism of action of the proteasome inhibitor PS-341 in T-cell lymphomas and HTLV-I associated adult T-cell leukemia/lymphoma

scientific article

Engagement of Transferrin Receptor by Polymeric IgA1: Evidence for a Positive Feedback Loop Involving Increased Receptor Expression and Mesangial Cell Proliferation in IgA Nephropathy

article

Establishment and Characterization of a Stromal Cell Line Derived From a Patient With Thoracic Endometriosis

scientific article published on 28 February 2019

Free HTLV-1 induces TLR7-dependent innate immune response and TRAIL relocalization in killer plasmacytoid dendritic cells

scientific article published on 10 December 2009

Galectin-1 and semaphorin-3A are two soluble factors conferring T-cell immunosuppression to bone marrow mesenchymal stem cell

scientific article published in July 2010

Human Muscle Progenitor Cells Displayed Immunosuppressive Effect through Galectin-1 and Semaphorin-3A

scientific article published on 23 April 2012

Human bone marrow adipocytes block granulopoiesis through neuropilin-1-induced granulocyte colony-stimulating factor inhibition.

scientific article

Human erythroleukemia: is the two-hit model of mouse leukemogenesis valid in human disease?

scientific article published on 31 May 2007

Immunological alterations and associated diseases in mandrills (Mandrillus sphinx) naturally co-infected with SIV and STLV.

scientific article published on 7 March 2014

Immunosuppressive role of semaphorin-3A on T cell proliferation is mediated by inhibition of actin cytoskeleton reorganization

scientific article published on 01 July 2006

Inhibition of both focal adhesion kinase and fibroblast growth factor receptor 2 pathways induces anti-tumor and anti-angiogenic activities

scientific article

Inhibitory effect of semaphorin-3A, a known axon guidance molecule, in the human thymocyte migration induced by CXCL12

scholarly article by Flavia Garcia et al published 30 August 2011 in Journal of Leukocyte Biology

Mast cell leukemia: identification of a new c-Kit mutation, dup(501-502), and response to masitinib, a c-Kit tyrosine kinase inhibitor.

scientific article published on 28 April 2012

NRPa-308, a new neuropilin-1 antagonist, exerts in vitro anti-angiogenic and anti-proliferative effects and in vivo anti-cancer effects in a mouse xenograft model

scientific article published on 27 October 2017

Natural antibodies sustain differentiation and maturation of human dendritic cells

scholarly article

Neuropilin-1 is involved in human T-cell lymphotropic virus type 1 entry

scientific article published on July 2006

Neuropilin-1 peptide-like ligands with proline mimetics, tested using the improved chemiluminescence affinity detection method

scientific article published on 25 January 2019

Neuropilin-1 regulates a new VEGF-induced gene, Phactr-1, which controls tubulogenesis and modulates lamellipodial dynamics in human endothelial cells.

scientific article

Neuropilins, semaphorins, and their role in thymocyte development

scientific article published on February 2009

Neuropilin‐1 is not a marker of human Foxp3+ Treg

scientific article published on 01 June 2009

New therapeutic approaches for adult T-cell leukaemia

scientific article

No association between Langerhans cell histiocytosis and human herpes virus 8.

scientific article published in September 2002

Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence

scientific article published on 28 March 2006

Prevention of mantle lymphoma tumor establishment by routing transferrin receptor toward lysosomal compartments

scientific article published on February 2007

Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells.

scientific article

RasV12 induces Survivin/AuroraB pathway conferring tumor cell apoptosis resistance.

scientific article published on 31 March 2010

Recent advances in adult T-cell leukemia therapy: focus on a new anti-transferrin receptor monoclonal antibody

scientific article published on 27 September 2007

Retinoids regulate survival and antigen presentation by immature dendritic cells

scientific article

Semaphorin 3F and neuropilin-2 control the migration of human T-cell precursors

scientific article

Short interfering RNA (siRNA), a novel therapeutic tool acting on angiogenesis

scientific article published on 6 July 2007

Structure-based discovery of a small non-peptidic Neuropilins antagonist exerting in vitro and in vivo anti-tumor activity on breast cancer model.

scientific article

Synthesis and structure-activity relationship of non-peptidic antagonists of neuropilin-1 receptor.

scientific article

Synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK inhibitors with anti-angiogenic activity

scientific article

T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells

scientific article published on 22 February 2007

Tax unleashed: fulminant Tax-positive Adult T-cell Leukemia/Lymphoma after failed allogeneic stem cell transplantation.

scientific article published in December 2009

Telomeres and telomerase: relevance and future prospects in systemic lupus erythematosus

scientific article published on 2 April 2010

The telomere/telomerase system in autoimmune and systemic immune-mediated diseases

scientific article published on 06 May 2010

Toll-like receptor 3 regulates cord blood-derived endothelial cell function in vitro and in vivo

scientific article published on 8 June 2013

Toll-like receptor control of glucocorticoid-induced apoptosis in human plasmacytoid predendritic cells (pDCs).

scientific article

Urea-Peptide Hybrids as VEGF-A<sub>165</sub>/NRP-1 Complex Inhibitors with Improved Receptor Affinity and Biological Properties

scientific article published on 23 December 2020

p120-Ras GTPase activating protein (RasGAP): a multi-interacting protein in downstream signaling

scientific article

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