List of works - Jörg Scheuermann

20 years of DNA-encoded chemical libraries.

scientific article

A DNA-Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition

scientific article published on 01 June 2018

A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks

scientific article published on 14 October 2020

A Small-Molecule Inhibitor of Lin28.

scientific article

A Specific and Covalent JNK-1 Ligand Selected from an Encoded Self-Assembling Chemical Library

scientific article

A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy

scholarly article by Gonçalo J. L. Bernardes et al published 15 December 2011 in Angewandte Chemie International Edition

A monoclonal antibody prevents aggregation of the NBD1 domain of the cystic fibrosis transmembrane conductance regulator

scientific article published on 30 November 2007

A portable albumin binder from a DNA-encoded chemical library

scientific article

Affinity enhancement of protein ligands by reversible covalent modification of neighboring lysine residues

scientific article published on 26 November 2018

Affinity-capture reagents for protein arrays

scientific article

Automated and enhanced extraction of a small molecule-drug conjugate using an enzyme-inhibitor interaction based SPME tool followed by direct analysis by ESI-MS

scientific article published on 30 October 2019

Automated screening for small organic ligands using DNA-encoded chemical libraries.

scientific article

Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format

scientific article published on 05 May 2020

Critical Evaluation of Photo-cross-linking Parameters for the Implementation of Efficient DNA-Encoded Chemical Library Selections

scientific article published on 06 March 2020

DNA-Encoded Chemical Libraries

DNA-encoded chemical libraries

scientific article

DNA-encoded chemical libraries for the discovery of MMP-3 inhibitors

scientific article

DNA-encoded chemical libraries: Achievements and remaining challenges

scientific article published on 23 April 2018

DNA-encoded chemical libraries: a tool for drug discovery and for chemical biology

scientific article

DNA-encoded chemical libraries: advancing beyond conventional small-molecule libraries

scientific article

Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions

scientific article

Diagnostic and therapeutic applications of recombinant antibodies: targeting the extra-domain B of fibronectin, a marker of tumor angiogenesis

scientific article published on January 2004

Discovery of TNF inhibitors from a DNA-encoded chemical library based on diels-alder cycloaddition

scientific article

Discovery of small-molecule interleukin-2 inhibitors from a DNA-encoded chemical library

scientific article

Drug discovery with DNA-encoded chemical libraries

scientific article

Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation.

scientific article published on 26 January 2015

Dual-pharmacophore DNA-encoded chemical libraries

scientific article published on 13 March 2015

Editorial overview: Next generation therapeutics: Creating and exploiting the chemistry of large numbers.

scientific article published on 15 April 2015

Encoded Self-Assembling Chemical Libraries

Encoded self-assembling chemical libraries

scientific article

High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries

scientific article

High-throughput sequencing for the identification of binding molecules from DNA-encoded chemical libraries

scientific article

Hit-Validation Methodologies for Ligands Isolated from DNA-Encoded Chemical Libraries.

scientific article

Identification of structure-activity relationships from screening a structurally compact DNA-encoded chemical library

scientific article published on 3 February 2015

Impact of a Central Scaffold on the Binding Affinity of Fragment Pairs Isolated from DNA-Encoded Self-Assembling Chemical Libraries.

scientific article

Interrogating target-specificity by parallel screening of a DNA-encoded chemical library against closely related proteins

scientific article published on 18 March 2015

Isolation of a small-molecule inhibitor of the antiapoptotic protein Bcl-xL from a DNA-encoded chemical library

scientific article

Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library

scientific article

Isolation of potent and specific trypsin inhibitors from a DNA-encoded chemical library

scientific article

Lead discovery by DNA-encoded chemical libraries

scientific article

Ligand-based vascular targeting of disease

scientific article published on January 2007

On the magnitude of the chelate effect for the recognition of proteins by pharmacophores scaffolded by self-assembling oligonucleotides

scientific article published on February 2006

Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries

scientific article

Quantitative Assessment of Affinity Selection Performance by Using DNA-Encoded Chemical Libraries

scientific article published on 20 February 2019

Quantitative PCR is a Valuable Tool to Monitor the Performance of DNA-Encoded Chemical Library Selections.

scientific article

Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection

scientific article published on 01 January 2020

Screening of copper and palladium-mediated reactions compatible with DNA-encoded chemical libraries

scientific article published on 01 April 2019

Selection of Carbonic Anhydrase IX Inhibitors from One Million DNA-Encoded Compounds

scientific article

Selection of streptavidin binders from a DNA-encoded chemical library

scientific article published in March 2006

Selective fragments for the CREBBP bromodomain identified from an Encoded Self-Assembly Chemical Library

scientific article published on 19 July 2020

Sequence determinants of a microtubule tip localization signal (MtLS).

scientific article

Site-specific traceless coupling of potent cytotoxic drugs to recombinant antibodies for pharmacodelivery

scientific article

Small targeted cytotoxics: current state and promises from DNA-encoded chemical libraries

scientific article

Special edition on DNA-Encoded chemical libraries

scientific article published on 01 December 2020

Systematic evaluation and optimization of modification reactions of oligonucleotides with amines and carboxylic acids for the synthesis of DNA-encoded chemical libraries

scientific article published on 25 July 2014

Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library

scientific article published on 10 June 2015

Unexpected observation of concentration-dependent dissociation rates for antibody–antigen complexes and other macromolecular complexes in competition experiments

article

Versatile protein recognition by the encoded display of multiple chemical elements on a constant macrocyclic scaffold.

scientific article

List of works by Jörg Scheuermann

20 years of DNA-encoded chemical libraries.

A DNA-Encoded Library of Chemical Compounds Based on Common Scaffolding Structures Reveals the Impact of Ligand Geometry on Protein Recognition

A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks

A Small-Molecule Inhibitor of Lin28.

A Specific and Covalent JNK-1 Ligand Selected from an Encoded Self-Assembling Chemical Library

A Traceless Vascular-Targeting Antibody-Drug Conjugate for Cancer Therapy

A monoclonal antibody prevents aggregation of the NBD1 domain of the cystic fibrosis transmembrane conductance regulator

A portable albumin binder from a DNA-encoded chemical library

Affinity enhancement of protein ligands by reversible covalent modification of neighboring lysine residues

Affinity-capture reagents for protein arrays

Automated and enhanced extraction of a small molecule-drug conjugate using an enzyme-inhibitor interaction based SPME tool followed by direct analysis by ESI-MS

Automated screening for small organic ligands using DNA-encoded chemical libraries.

Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format

Critical Evaluation of Photo-cross-linking Parameters for the Implementation of Efficient DNA-Encoded Chemical Library Selections

DNA-Encoded Chemical Libraries

DNA-encoded chemical libraries

DNA-encoded chemical libraries for the discovery of MMP-3 inhibitors

DNA-encoded chemical libraries: Achievements and remaining challenges

DNA-encoded chemical libraries: a tool for drug discovery and for chemical biology

DNA-encoded chemical libraries: advancing beyond conventional small-molecule libraries

Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions

Diagnostic and therapeutic applications of recombinant antibodies: targeting the extra-domain B of fibronectin, a marker of tumor angiogenesis

Discovery of TNF inhibitors from a DNA-encoded chemical library based on diels-alder cycloaddition

Discovery of small-molecule interleukin-2 inhibitors from a DNA-encoded chemical library

Drug discovery with DNA-encoded chemical libraries

Dual-display of small molecules enables the discovery of ligand pairs and facilitates affinity maturation.

Dual-pharmacophore DNA-encoded chemical libraries

Editorial overview: Next generation therapeutics: Creating and exploiting the chemistry of large numbers.

Encoded Self-Assembling Chemical Libraries

Encoded self-assembling chemical libraries

High-throughput sequencing allows the identification of binding molecules isolated from DNA-encoded chemical libraries

High-throughput sequencing for the identification of binding molecules from DNA-encoded chemical libraries

Hit-Validation Methodologies for Ligands Isolated from DNA-Encoded Chemical Libraries.

Identification of structure-activity relationships from screening a structurally compact DNA-encoded chemical library

Impact of a Central Scaffold on the Binding Affinity of Fragment Pairs Isolated from DNA-Encoded Self-Assembling Chemical Libraries.

Interrogating target-specificity by parallel screening of a DNA-encoded chemical library against closely related proteins

Isolation of a small-molecule inhibitor of the antiapoptotic protein Bcl-xL from a DNA-encoded chemical library

Isolation of high-affinity trypsin inhibitors from a DNA-encoded chemical library

Isolation of potent and specific trypsin inhibitors from a DNA-encoded chemical library

Lead discovery by DNA-encoded chemical libraries

Ligand-based vascular targeting of disease

On the magnitude of the chelate effect for the recognition of proteins by pharmacophores scaffolded by self-assembling oligonucleotides

Optimized Reaction Conditions for Amide Bond Formation in DNA-Encoded Combinatorial Libraries

Quantitative Assessment of Affinity Selection Performance by Using DNA-Encoded Chemical Libraries

Quantitative PCR is a Valuable Tool to Monitor the Performance of DNA-Encoded Chemical Library Selections.

Quantitative and Qualitative Analysis of Humoral Immunity Reveals Continued and Personalized Evolution in Chronic Viral Infection

Screening of copper and palladium-mediated reactions compatible with DNA-encoded chemical libraries

Selection of Carbonic Anhydrase IX Inhibitors from One Million DNA-Encoded Compounds

Selection of streptavidin binders from a DNA-encoded chemical library

Selective fragments for the CREBBP bromodomain identified from an Encoded Self-Assembly Chemical Library

Sequence determinants of a microtubule tip localization signal (MtLS).

Site-specific traceless coupling of potent cytotoxic drugs to recombinant antibodies for pharmacodelivery

Small targeted cytotoxics: current state and promises from DNA-encoded chemical libraries

Special edition on DNA-Encoded chemical libraries

Systematic evaluation and optimization of modification reactions of oligonucleotides with amines and carboxylic acids for the synthesis of DNA-encoded chemical libraries

Tankyrase 1 Inhibitors with Drug-like Properties Identified by Screening a DNA-Encoded Chemical Library

Unexpected observation of concentration-dependent dissociation rates for antibody–antigen complexes and other macromolecular complexes in competition experiments

Versatile protein recognition by the encoded display of multiple chemical elements on a constant macrocyclic scaffold.

“Cap-and-Catch” Purification for Enhancing the Quality of Libraries of DNA Conjugates