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List of works by Antonio Bianco

A Common DIO2 Polymorphism And Alzheimer's Disease Dementia in African And European Americans.

scientific article published on 22 February 2018

A TRbeta-selective agonist confers resistance to diet-induced obesity

scientific article

A novel pathway regulates thyroid hormone availability in rat and human hypothalamic neurosecretory neurons

scientific article

A transgenic mouse model for detection of tissue-specific thyroid hormone action.

scientific article

Absence of myocardial thyroid hormone inactivating deiodinase results in restrictive cardiomyopathy in mice

scientific article

Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis

scientific article

Activation and inactivation of thyroid hormone by deiodinases: local action with general consequences.

scientific article published on February 2008

Adaptive activation of thyroid hormone and energy expenditure

scientific article

Adaptive thermogenesis in hummingbirds.

scientific article

Adenosine 3',5'-monophosphate and thyroid hormone control of uncoupling protein messenger ribonucleic acid in freshly dispersed brown adipocytes

scientific article published on 01 May 1992

Agouti-related protein (AGRP) has a central inhibitory action on the hypothalamic-pituitary-thyroid (HPT) axis; comparisons between the effect of AGRP and neuropeptide Y on energy homeostasis and the HPT axis

scientific article published in October 2002

American Thyroid Association Guide to investigating thyroid hormone economy and action in rodent and cell models

scientific article published on 12 December 2013

Amiodarone and the thyroid physiology, pathophysiology, diagnosis and management

scientific article published on 20 September 2018

An Online Survey of Hypothyroid Patients Demonstrates Prominent Dissatisfaction.

scientific article published on 5 April 2018

An inside job.

scientific article published in July 2007

Atypical expression of type 2 iodothyronine deiodinase in thyrotrophs explains the thyroxine-mediated pituitary thyrotropin feedback mechanism.

scientific article published on 5 January 2006

Bacterial lipopolysaccharide (LPS)-induced type 2 iodothyronine deiodinase (D2) activation in the mediobasal hypothalamus (MBH) is independent of the LPS-induced fall in serum thyroid hormone levels

scientific journal article

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

scientific article

Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases.

scientific article

Calcium-dependent protein kinase-C activity in human adrenocortical neoplasms, hyperplastic adrenals, and normal adrenocortical tissue

scientific article published on 01 September 1994

Cellular and molecular basis of deiodinase-regulated thyroid hormone signaling

scientific article

Cellular and structural biology of the deiodinases

scientific article

Central role of brown adipose tissue thyroxine 5'-deiodinase on thyroid hormone-dependent thermogenic response to cold.

scientific article published on April 1991

Characterization of the nuclear factor-kappa B responsiveness of the human dio2 gene.

scientific article published on 25 May 2006

Chronic cardiac-specific thyrotoxicosis increases myocardial beta-adrenergic responsiveness.

scientific article

Cognitive decline following incident and preexisting diabetes mellitus in a population sample

scientific article published on 21 September 2016

Cold exposure rapidly induces virtual saturation of brown adipose tissue nuclear T3 receptors

scientific article published on 01 October 1988

Combined treatment with caffeic and ferulic acid from Baccharis uncinella C. DC. (Asteraceae) protects against metabolic syndrome in mice.

scientific article published on 2 February 2016

Conversion of thyroxine (T4) to T3 and rT3 in human leucocyte suspension: its application to clinical investigation

scientific article published on 01 March 1985

Corticosterone inhibits uncoupling protein gene expression in brown adipose tissue.

scientific article

Coupling between Nutrient Availability and Thyroid Hormone Activation

scientific article

Covering the base-pairs in iodothyronine deiodinase-1 biology: holes remain in the lineup

scientific article published on 01 October 2009

Crossing the hurdles of thyroid hormone receptor-α activation

scientific article

Defending plasma T3 is a biological priority

scientific article

Deiodinase-mediated thyroid hormone inactivation minimizes thyroid hormone signaling in the early development of fetal skeleton

scientific article

Deiodinases: implications of the local control of thyroid hormone action

scientific article

Development of compensatory thermogenesis in response to overfeeding in hypothyroid rats

scientific article published on 01 August 1999

Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine

scientific article

Differential effects of central leptin, insulin, or glucose administration during fasting on the hypothalamic-pituitary-thyroid axis and feeding-related neurons in the arcuate nucleus.

scientific article published on 6 October 2005

Disruption of beta3 adrenergic receptor increases susceptibility to DIO in mouse.

scientific article published on 26 September 2016

Disruption of thyroid hormone activation in type 2 deiodinase knockout mice causes obesity with glucose intolerance and liver steatosis only at thermoneutrality

scientific article

Disruption of type 2 iodothyronine deiodinase activity in cultured human glial cells by polybrominated diphenyl ethers.

scientific article published on 2 June 2015

Does Sex Bias Play a Role for Dissatisfied Patients With Hypothyroidism?

scientific article published on 09 July 2018

Early Developmental Disruption of Type 2 Deiodinase Pathway in Mouse Skeletal Muscle Does Not Impair Muscle Function.

scientific article published on 14 December 2016

Effects of hypothyroidism on brown adipose tissue adenylyl cyclase activity

scientific article published on 01 December 1996

Effects of rexinoids on thyrotrope function and the hypothalamic-pituitary-thyroid axis

scientific article published on 23 November 2005

Effects of thyroid hormone administration and estrogen deficiency on bone mass of female rats

scientific article published on 01 December 1997

Endoplasmic reticulum stress decreases intracellular thyroid hormone activation via an eIF2a-mediated decrease in type 2 deiodinase synthesis.

scientific article published on 3 November 2011

Endoplasmic reticulum-associated degradation of the human type 2 iodothyronine deiodinase (D2) is mediated via an association between mammalian UBC7 and the carboxyl region of D2.

scientific article

Epicardial adipose tissue has a unique transcriptome modified in severe coronary artery disease

scientific article published on 09 May 2015

Epicardial adipose tissue: emerging physiological, pathophysiological and clinical features

scientific article published on 16 August 2011

Evidence of UCP1-independent regulation of norepinephrine-induced thermogenesis in brown fat

scientific article published on 01 August 2000

Expression patterns of WSB-1 and USP-33 underlie cell-specific posttranslational control of type 2 deiodinase in the rat brain.

scientific article

Extrathyroidal conversion of thyroxine to 3,5,3'-triiodothyronine in cold-acclimated thyroxine-maintained thyroidectomized rats

scientific article published on 01 January 1986

Feeding and metabolism in mice lacking pituitary adenylate cyclase-activating polypeptide

scientific article published on 27 December 2007

For some, L-thyroxine replacement might not be enough: a genetic rationale.

scientific article published in May 2009

Gastrin changes in the gastric antrum G-cells and in serum gastrin levels after 80% jejunoileal resection in rats

scientific article

Guidelines for the treatment of hypothyroidism: prepared by the american thyroid association task force on thyroid hormone replacement

scientific article

Hepatic Inactivation of the Type 2 Deiodinase Confers Resistance to Alcoholic Liver Steatosis

scientific article published on 26 April 2019

Hormonal regulation of malic enzyme and glucose-6-phosphate dehydrogenase in brown adipose tissue

scientific article published on 01 June 1993

Human type 3 iodothyronine selenodeiodinase is located in the plasma membrane and undergoes rapid internalization to endosomes

scientific article published on 4 November 2002

Hypothyroidism and hypertension: fact or myth? - Authors' reply

scientific article published in January 2018

Hypothyroidism.

scientific article

Hypoxia-inducible factor induces local thyroid hormone inactivation during hypoxic-ischemic disease in rats

scientific article

Impaired metabolic effects of a thyroid hormone receptor beta-selective agonist in a mouse model of diet-induced obesity.

scientific article

In vivo dimerization of types 1, 2, and 3 iodothyronine selenodeiodinases

scientific article

Inactivation of the adrenergic receptor β2 disrupts glucose homeostasis in mice

scientific article published on June 2014

Induction of Type 2 Iodothyronine Deiodinase After Status Epilepticus Modifies Hippocampal Gene Expression in Male Mice

scientific article published on 01 August 2018

Influence of body composition on the bone mass of postmenopausal women

scientific article published on 01 November 1997

Influence of mast cells on thyroid function

scientific article published on 01 June 1983

Inhibition of the type 2 iodothyronine deiodinase underlies the elevated plasma TSH associated with amiodarone treatment

scientific article

Is a Normal TSH Synonymous With "Euthyroidism" in Levothyroxine Monotherapy?

scientific article

LXRs regulate the balance between fat storage and oxidation.

scientific article published in April 2005

Lack of reduction in body fat after treatment with insulin-like growth factor-I in two children with growth hormone gene deletions

scientific article published on 01 April 2000

Lipopolysaccharide induces type 2 iodothyronine deiodinase in the mediobasal hypothalamus: implications for the nonthyroidal illness syndrome

scientific article

Loss of Mpzl3 function causes various skin abnormalities and greatly reduced adipose depots

scientific article

METAL COORDINATED POLY-ZINC-LIOTHYRONINE PROVIDES STABLE CIRCULATING T3 LEVELS IN HYPOTHYROID RATS

scientific article published on 01 November 2018

Maternal inheritance of an inactive type III deiodinase gene allele affects mouse pancreatic β-cells and disrupts glucose homeostasis

scientific article

Metabolic effects of thyroid hormones-beyond traditional prospects

scientific article published on 01 February 2008

Metabolic instability of type 2 deiodinase is transferable to stable proteins independently of subcellular localization

scientific article published on 23 August 2006

Mice lacking Pctp /StarD2 exhibit increased adaptive thermogenesis and enlarged mitochondria in brown adipose tissue

scientific article

Mice lacking brain-type creatine kinase activity show defective thermoregulation

scientific article

Mice with impaired extrathyroidal thyroxine to 3,5,3'-triiodothyronine conversion maintain normal serum 3,5,3'-triiodothyronine concentrations

scientific article published on 30 November 2006

Mice with targeted disruption of the Dio2 gene have cold-induced overexpression of the uncoupling protein 1 gene but fail to increase brown adipose tissue lipogenesis and adaptive thermogenesis.

scientific article published in March 2004

Minireview: Cracking the Metabolic Code for Thyroid Hormone Signaling ⬇️

scientific article published on June 28, 2011

Morphometric dual-energy X-ray absorptiometry of the spine: report of a large series and correlation with axial bone mineral density

scientific article published on 01 September 1999

Myocardial Inactivation of Thyroid Hormones in Patients with Aortic Stenosis

scientific article published on 17 January 2017

Neonatal thyroxine activation modifies epigenetic programming of the liver

scientific article published on 21 July 2021

Neuronal hypoxia induces Hsp40-mediated nuclear import of type 3 deiodinase as an adaptive mechanism to reduce cellular metabolism.

scientific article

Neuropeptide Y1 and Y5 receptors mediate the effects of neuropeptide Y on the hypothalamic-pituitary-thyroid axis

scientific journal article

New insights into the variable effectiveness of levothyroxine monotherapy for hypothyroidism.

scientific article published on 8 September 2015

New insights into thyroid hormone replacement therapy

scientific article

Nuclear 3,5,3'-triiodothyronine (T3) in brown adipose tissue: receptor occupancy and sources of T3 as determined by in vivo techniques

Of rats and men: thyroid homeostasis in rodents and human beings – Authors' reply

scientific article published on 01 December 2015

Paracrine signaling by glial cell-derived triiodothyronine activates neuronal gene expression in the rodent brain and human cells.

scientific article

Paradigms of Dynamic Control of Thyroid Hormone Signaling

scientific article published on 01 August 2019

Pathophysiological relevance of deiodinase polymorphism

scientific article

Patient Context and Thyrotropin Levels Are Important When Considering Treatment of Subclinical Hypothyroidism

scientific article published on 03 October 2019

Perilipin promotes hormone-sensitive lipase-mediated adipocyte lipolysis via phosphorylation-dependent and -independent mechanisms.

scientific article published on 4 April 2006

Perinatal deiodinase 2 expression in hepatocytes defines epigenetic susceptibility to liver steatosis and obesity.

scientific article

Possible mechanism of action of cholesterol enriched diet on the thyroid.

scientific article published in December 1981

Prevalent polymorphism in thyroid hormone-activating enzyme leaves a genetic fingerprint that underlies associated clinical syndromes

scientific article

Quantitation of brown adipose tissue perfusion in transgenic mice using near-infrared fluorescence imaging

scientific article published on 01 January 2003

Reawakened interest in type III iodothyronine deiodinase in critical illness and injury

scientific article

Regulation of thyroid hormone activation via the liver X-receptor/retinoid X-receptor pathway.

scientific article

Responsiveness to thyroid hormone and to ambient temperature underlies differences between brown adipose tissue and skeletal muscle thermogenesis in a mouse model of diet-induced obesity

scientific article

S-nitrosoglutathione reductase-dependent PPARγ denitrosylation participates in MSC-derived adipogenesis and osteogenesis

scientific article

Scope and limitations of iodothyronine deiodinases in hypothyroidism

scientific article

Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

scientific article

Sociodemographic Disparities in the Treatment of Hypothyroidism: NHANES 2007-2012

scientific article published on 15 March 2021

Sonic hedgehog-induced type 3 deiodinase blocks thyroid hormone action enhancing proliferation of normal and malignant keratinocytes.

scholarly article

Substrate-induced down-regulation of human type 2 deiodinase (hD2) is mediated through proteasomal degradation and requires interaction with the enzyme's active center

scientific article published on 01 March 2000

Sustained Release T3 Therapy: Animal Models and Translational Applications

scientific article published on 13 August 2019

Systemic Thyroid Hormone Status During Levothyroxine Therapy In Hypothyroidism: A Systematic Review and Meta-Analysis

scholarly article by Elizabeth A. McAninch et al published 15 August 2018 in The Journal of Clinical Endocrinology and Metabolism

Temporal Pole Responds to Subtle Changes in Local Thyroid Hormone Signaling

scientific article published on 22 September 2020

The Deiodinase Trio and Thyroid Hormone Signaling

scientific article published on 01 January 2018

The E3 ubiquitin ligase TEB4 mediates degradation of type 2 iodothyronine deiodinase

scientific article

The Foxo1-Inducible Transcriptional Repressor Zfp125 Causes Hepatic Steatosis and Hypercholesterolemia.

scientific article published in January 2018

The Hedgehog-inducible ubiquitin ligase subunit WSB-1 modulates thyroid hormone activation and PTHrP secretion in the developing growth plate

scientific article

The History and Future of Treatment of Hypothyroidism

scientific article

The Relationship Between Work Relative Value Unit Awareness and Work Relative Value Unit Accumulation Among Physicians

The Swinging Pendulum in Treatment for Hypothyroidism: From (and Toward?) Combination Therapy

scientific article published on 09 July 2019

The chemical chaperones tauroursodeoxycholic and 4-phenylbutyric acid accelerate thyroid hormone activation and energy expenditure

scientific article

The iodothyronine selenodeiodinases are thioredoxin-fold family proteins containing a glycoside hydrolase clan GH-A-like structure

scientific article

The role of thyroid hormone and brown adipose tissue in energy homoeostasis

scientific article published on 18 October 2013

The small polyphenolic molecule kaempferol increases cellular energy expenditure and thyroid hormone activation

scientific article published on March 2007

The thyroid hormone-inactivating deiodinase functions as a homodimer

scientific article

The thyroid hormone-inactivating type III deiodinase is expressed in mouse and human beta-cells and its targeted inactivation impairs insulin secretion

scientific article (publication date: October 2011)

The type 2 deiodinase A/G (Thr92Ala) polymorphism is associated with decreased enzyme velocity and increased insulin resistance in patients with type 2 diabetes mellitus

scientific article published on 29 March 2005

The type 2 iodothyronine deiodinase is essential for adaptive thermogenesis in brown adipose tissue

scientific article

The type II deiodinase is retrotranslocated to the cytoplasm and proteasomes via p97/Atx3 complex.

scientific article

The use of recombinant human thyrotropin produced by Chinese hamster ovary cells for the preparation of immunoassay reagents

scientific article published in January 1996

Thyroid Hormone Signaling in Male Mouse Skeletal Muscle Is Largely Independent of D2 in Myocytes.

scientific article

Thyroid Hormone and the Neuroglia: Both Source and Target ⬇️

scientific article published on August 23, 2011

Thyroid function disturbance and type 3 iodothyronine deiodinase induction after myocardial infarction in rats a time course study.

scientific article

Thyroid function in critically ill patients

scientific article published on 10 June 2015

Thyroid hormone activation by type 2 deiodinase mediates exercise-induced peroxisome proliferator-activated receptor-γ coactivator-1α expression in skeletal muscle

scientific article published on 15 June 2016

Thyroid hormone deiodinases and cancer

scientific article

Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.

scientific article

Thyroid hormone receptor beta-specific agonist GC-1 increases energy expenditure and prevents fat-mass accumulation in rats.

scientific article published in April 2007

Thyroid hormone replacement therapy: three 'simple' questions, complex answers

scientific article published on 27 June 2012

Thyroid hormone signaling in energy homeostasis and energy metabolism

scientific article published on 20 February 2014

Thyroid hormone--sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform--specific

scientific article

Thyroid hormone-related regulation of gene expression in human fatty liver

scientific article published on 23 June 2009

Thyroxine 5'-deiodination mediates norepinephrine-induced lipogenesis in dispersed brown adipocytes

scientific article published on 01 February 1998

Thyroxine induced transformation in sarcoplasmic reticulum of rabbit soleus and psoas muscles

scientific article

Tissue-Specific Inactivation of Type 2 Deiodinase Reveals Multilevel Control of Fatty Acid Oxidation by Thyroid Hormone in the Mouse. Diabetes 2014;63:1594–1604.

scientific article published on 17 July 2014

Tissue-specific inactivation of type 2 deiodinase reveals multilevel control of fatty acid oxidation by thyroid hormone in the mouse.

scientific article published on 31 January 2014

Transcriptional and posttranscriptional mechanisms in uncoupling protein mRNA response to cold

scientific article published on 01 January 1992

Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage.

scientific article published on October 2013

Triiodothyronine amplifies norepinephrine stimulation of uncoupling protein gene transcription by a mechanism not requiring protein synthesis

scientific article published on 01 December 1988

Triumphs of the thyroid despite lesser conversion

scientific article

Type 1 iodothyronine deiodinase is a sensitive marker of peripheral thyroid status in the mouse.

scientific article published on 9 December 2004

Type 2 Deiodinase Disruption in Astrocytes Results in Anxiety-Depressive-Like Behavior in Male Mice

scientific article published on 8 August 2016

Type 2 deiodinase at the crossroads of thyroid hormone action

scientific article published on 12 June 2011

Type 2 deiodinase polymorphism causes ER stress and hypothyroidism in the brain

scientific article published on 03 December 2018

Type 2 iodothyronine deiodinase is highly expressed in germ cells of adult rat testis.

scientific article

Type 2 iodothyronine selenodeiodinase is expressed throughout the mouse skeleton and in the MC3T3-E1 mouse osteoblastic cell line during differentiation.

scientific article

Ubc6p and ubc7p are required for normal and substrate-induced endoplasmic reticulum-associated degradation of the human selenoprotein type 2 iodothyronine monodeiodinase

scientific article

Ubiquitination-induced conformational change within the deiodinase dimer is a switch regulating enzyme activity.

scientific article published on 23 April 2007

Urgent need for further research in subclinical hypothyroidism

scientific article published on 01 September 2019

Use of Statins Among Patients Taking Levothyroxine: an Observational Drug Utilization Study Across Sites

scientific article published on 06 March 2021

Wnt signaling regulates mitochondrial physiology and insulin sensitivity

scientific journal article

[Basedow-Graves' disease: analysis of various parameters in the prognosis of remission after clinical treatment]

scientific article published on 01 March 1989

[Bone mineral density: correlation with body weight, height, bone age and insulin-like growth factor]

scientific article published on 01 July 1997

[Changes in serum and hepatic lipids after extensive intestinal resection in the rat]

scientific article published on 01 July 1985

[Characterization of the binding of 125I-TSH to its receptor in low-uptake thyroid hyperplasias]

scientific article published on 01 July 1985

[Histologic and histochemical evaluation of the exocrine pancreas in rats subjected to resection or extensive jejunoileal bypass]

scientific article published on 01 July 1988

[Impact factor. The editor's report?]

scientific article published on 01 June 2004

[Thyroxine (T4) to 3,5,3'-triiodothyronine (T3) and 3,3',5'-triiodothyronine (reverse T3) conversion in human leukocyte suspensions. Study in hyper and hypothyroidism states]

scientific article published on 01 March 1984

[Vertebral and femoral bone mineral density of 724 caucasian Brazilian women: influence of age and body weight]

scientific article published on 01 April 1997

betaAR signaling required for diet-induced thermogenesis and obesity resistance

scientific article

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