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List of works by Teresa Lambe

A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA

scientific article

A Multi-Filovirus Vaccine Candidate: Co-Expression of Ebola, Sudan, and Marburg Antigens in a Single Vector

scientific article published on 21 May 2020

A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

scientific journal article

A T cell-inducing influenza vaccine for the elderly: safety and immunogenicity of MVA-NP+M1 in adults aged over 50 years

scientific article

A naturally protective epitope of limited variability as an influenza vaccine target

scientific article published in Nature Communications

A potent neutralizing epitope of limited variability in the head domain of haemagglutinin as a novel influenza vaccine target

A review of Phase I trials of Ebola virus vaccines: what can we learn from the race to develop novel vaccines?

scientific article (publication date: 26 May 2017)

A single dose of ChAdOx1 MERS provides broad protective immunity against a variety of MERS-CoV strains

scientific article published on 14 April 2020

A single dose of ChAdOx1 MERS provides protective immunity in rhesus macaques

scientific article published on 01 May 2020

A single-dose ChAdOx1-vectored vaccine provides complete protection against Nipah Bangladesh and Malaysia in Syrian golden hamsters.

scientific article published on 6 June 2019

Activation of cross-reactive mucosal T and B cell responses in human nasopharynx-associated lymphoid tissue in vitro by Modified Vaccinia Ankara-vectored influenza vaccines.

scientific article

Antibody evasion by the P.1 strain of SARS-CoV-2

scientific article

B-cell Tolerance

scientific article published on 01 February 2006

CD4 T cell-dependent autoimmunity against a melanocyte neoantigen induces spontaneous vitiligo and depends upon Fas-Fas ligand interactions

scientific article published in September 2006

CD4+ T Follicular Helper Cells in Human Tonsils and Blood Are Clonally Convergent but Divergent from Non-Tfh CD4+ Cells

scientific article published on 01 January 2020

CITED1 homozygous null mice display aberrant pubertal mammary ductal morphogenesis

scientific article published on 01 March 2006

ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in mice ⬇️

scientific article published on June 2017

ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7

scientific article

ChAdOx1 nCoV-19 (AZD1222) protects Syrian hamsters against SARS-CoV-2 B.1.351 and B.1.1.7.

scientific article published on 07 October 2021

ChAdOx1 nCoV-19 vaccination prevents SARS-CoV-2 pneumonia in rhesus macaques

scientific article published on 14 May 2020

ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques

scientific article published on 30 July 2020

Chimpanzee adenoviral vectors as vaccines for outbreak pathogens

scientific article published on 30 October 2017

Clinical Advances in Viral-Vectored Influenza Vaccines

Clinical assessment of a novel recombinant simian adenovirus ChAdOx1 as a vectored vaccine expressing conserved Influenza A antigens

scientific article published on 30 December 2013

Commmentary 7

Corrections. Emergency Ebola response: a new approach to the rapid design and development of vaccines against emerging diseases

scientific article published on 20 January 2015

Corrigendum to "Heterologous Two-dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-lasting Cellular Immunity to Influenza Virus A in Healthy Adults" [EBioMedicine 29 (2018) 146-154].

scientific article published on 5 May 2018

DNA repair is limiting for haematopoietic stem cells during ageing

scientific journal article

DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice

scientific article

DOCK8 is critical for the survival and function of NKT cells

scientific article published on 08 August 2013

DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory

scientific journal article

Detection of Vaccine-Induced Antibodies to Ebola Virus in Oral Fluid

scientific article published on January 2016

Differential expression of connexin 43 in mouse mammary cells

scientific article published on 06 March 2006

Divergent trajectories of antiviral memory after SARS-CoV-2 infection

scientific article published on 10 March 2022

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

scientific article

Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B.1.1.7): an exploratory analysis of a randomised controlled trial

scientific article

Efficacy of the ChAdOx1 nCoV-19 Covid-19 Vaccine against the B.1.351 Variant

scholarly article by Andrew Pollard published in 2021

Emergency Ebola response: a new approach to the rapid design and development of vaccines against emerging diseases

scientific article

Enhancing cellular immunogenicity of MVA-vectored vaccines by utilizing the F11L endogenous promoter

scientific article published on 23 November 2015

Erratum: Corrigendum: Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

article

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

scientific article published on 27 July 2020

Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine induced sera

scientific article published in February 2021

Expression and cellular immunogenicity of a transgenic antigen driven by endogenous poxviral early promoters at their authentic loci in MVA

scientific article (publication date: 2012)

Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses

scientific article published in 2022

HLA-E: exploiting pathogen-host interactions for vaccine development

article

Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults.

scientific article

High glucose-altered gene expression in mesangial cells. Actin-regulatory protein gene expression is triggered by oxidative stress and cytoskeletal disassembly.

scientific article

Humoral Immunogenicity and Efficacy of a Single Dose of ChAdOx1 MERS Vaccine Candidate in Dromedary Camels

scientific article published on 08 November 2019

Hyper IgE in New Zealand black mice due to a dominant-negative CD23 mutation.

scientific article published on 19 October 2004

Identification of a Steap3 endosomal targeting motif essential for normal iron metabolism

scientific journal article

Immune privilege or privileged immunity?

scientific article published on 02 July 2008

Immunity against heterosubtypic influenza virus induced by adenovirus and MVA expressing nucleoprotein and matrix protein-1.

scientific article published on January 2013

Immunodeficiency and Abnormal B Cell Synapse Formation due to DOCK8 Mutations in Mice

scholarly article by Katrina Randall et al published January 2010 in Clinical Immunology

Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques

scientific article published on 10 September 2021

Improved adjuvanting of seasonal influenza vaccines: preclinical studies of MVA-NP+M1 coadministration with inactivated influenza vaccine

scientific article

Infection- or AZD1222 vaccine-mediated immunity reduces SARS-CoV-2 transmission but increases Omicron competitiveness in hamsters

scientific article published on 18 October 2023

Intranasal ChAdOx1 nCoV-19/AZD1222 vaccination reduces viral shedding after SARS-CoV-2 D614G challenge in preclinical models

scientific article published on 18 August 2021

Limited peripheral T cell anergy predisposes to retinal autoimmunity

scientific article

MVA-NP+M1 vaccine activates mucosal M1-specific T cell immunity and tissue-resident memory T cells in human nasopharynx-associated lymphoid tissue

scientific article published on 19 November 2019

Measuring Cellular Immunity to Influenza: Methods of Detection, Applications and Challenges

scientific article

MyD88-dependent autoimmune disease in Lyn-deficient mice

scientific article published on 01 October 2007

Novel Bivalent Viral-Vectored Vaccines Induce Potent Humoral and Cellular Immune Responses Conferring Protection against Stringent Influenza A Virus Challenge.

scientific article

Novel Viral Vectored Vaccines for the Prevention of Influenza ⬇️

scientific article published on October 24, 2012

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

scientific article

Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens

scientific article

Potent CD8+ T-cell immunogenicity in humans of a novel heterosubtypic influenza A vaccine, MVA-NP+M1.

scientific article

Preliminary assessment of the efficacy of a T-cell-based influenza vaccine, MVA-NP+M1, in humans

scientific article

Protection from liver-stage malaria is dependent on a fine balance between the number of infected hepatocytes and effector CD8+ T cells.

scientific article published on 22 September 2014

Protective efficacy of a novel simian adenovirus vaccine against lethal MERS-CoV challenge in a transgenic human DPP4 mouse model

scientific article published on 16 October 2017

Reduced Ebola vaccine responses in CMV+ young adults is associated with expansion of CD57+KLRG1+ T cells

scientific article published on 01 July 2020

Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera

scientific article

Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum

Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK

scientific article published on 08 December 2020

Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial

scientific article published on 18 November 2020

Safety and immunogenicity of a candidate Middle East respiratory syndrome coronavirus viral-vectored vaccine: a dose-escalation, open-label, non-randomised, uncontrolled, phase 1 trial

scientific article published on 20 April 2020

Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial

scientific article published on 20 July 2020

Seroprevalence of anti-SARS-CoV-2 IgG antibodies in Kenyan blood donors

scientific article

Single-dose administration and the influence of the timing of the booster dose on immunogenicity and efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine: a pooled analysis of four randomised trials

scientific article published in February 2021

Spontaneous B cell hyperactivity in autoimmune-prone MRL mice

scientific article published on 30 May 2006

T-cell responses in children to internal influenza antigens, 1 year after immunization with pandemic H1N1 influenza vaccine, and response to revaccination with seasonal trivalent-inactivated influenza vaccine

scientific article

The Threshold of Protection from Liver-Stage Malaria Relies on a Fine Balance between the Number of Infected Hepatocytes and Effector CD8+ T Cells Present in the Liver

scientific article published on 13 January 2017

The early landscape of COVID-19 vaccine development in the UK and rest of the world

scientific article published on 27 May 2020

The essential role of DOCK8 in humoral immunity

scientific article published on January 2010

Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

scientific article

Vaccination With Viral Vectors Expressing Chimeric Hemagglutinin, NP and M1 Antigens Protects Ferrets Against Influenza Virus Challenge

scientific article published on 21 August 2019

Vaccination with viral vectors expressing NP, M1 and chimeric hemagglutinin induces broad protection against influenza virus challenge in mice

scientific article published on 06 August 2019

Vaccine platforms for the prevention of Lassa fever

scientific article published on 23 April 2019

Viewpoint 1

scientific article published on 01 February 2008

Viral vectors as vaccine platforms: from immunogenicity to impact

scientific article

Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?

Vitiligo pathogenesis: autoimmune disease, genetic defect, excessive reactive oxygen species, calcium imbalance, or what else?

scholarly article by Lübeck Ralf Paus et al published February 2008 in Experimental Dermatology

What Lies Beneath: Antibody Dependent Natural Killer Cell Activation by Antibodies to Internal Influenza Virus Proteins

scientific article published on 28 April 2016

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