List of works - Gabriel R. Fries

A promising era for epigenetic research: revealing the molecular signature of neuropsychiatric disorders

scientific article published on 01 November 2019

Accelerated aging in bipolar disorder: A comprehensive review of molecular findings and their clinical implications

scientific article published on 01 February 2020

Accelerated epigenetic aging and mitochondrial DNA copy number in bipolar disorder

scientific article published on 11 December 2017

Accelerated hippocampal biological aging in bipolar disorder

scientific article published on 19 November 2019

Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus

scientific article published on 8 August 2007

Administration of cannabidiol and imipramine induces antidepressant-like effects in the forced swimming test and increases brain-derived neurotrophic factor levels in the rat amygdala

scientific article

Alterations in Plasma Kynurenine Pathway Metabolites in Children and Adolescents with Bipolar Disorder and Unaffected Offspring of Bipolar Parents: A preliminary study

scientific article published on 24 October 2020

Analyzing leukocyte telomere length in bipolar disorder: Authors' reply

scientific article published in July 2017

Angiogenic gene networks are dysregulated in opioid use disorder: evidence from multi-omics and imaging of postmortem human brain

scientific article published on 12 August 2021

Anhedonia in cocaine use disorder is associated with inflammatory gene expression

scientific article published in PLoS ONE

Are lithium effects dependent on genetic/epigenetic architecture?

scientific article published on 01 January 2019

Biomarkers for bipolar disorder: current status and challenges ahead

scientific article published on 28 November 2018

Biomarkers in first-degree relatives of patients with bipolar disorder: what can they tell us?

scientific article published in July 2017

Brain Gene Expression Pattern of Subjects with Completed Suicide and Comorbid Substance Use Disorder

scientific article published on 12 November 2018

Brain-derived neurotrophic factor and inflammatory markers in school-aged children with early trauma

scientific article published on 17 November 2014

Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis

scientific article published on 06 May 2011

Brain-derived neurotrophic factor gene val66met polymorphism and executive functioning in patients with bipolar disorder

scientific article published in June 2009

Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine

scientific article published on 24 November 2015

Childhood trauma, family history, and their association with mood disorders in early adulthood

scientific article published on 30 January 2016

Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels

scientific article

Cognition and functioning in bipolar depression

scientific article

Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients

scientific article published on 07 December 2020

Damage-associated molecular patterns and immune activation in bipolar disorder

scientific article published on 16 April 2015

Decreased brain-derived neurotrophic factor in medicated and drug-free bipolar patients

scientific article

Decreased serum neurotrophin 3 in chronically medicated schizophrenic males

scientific article published on 15 April 2008

Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder

scientific article published in February 2018

Distinct lithium-induced gene expression effects in lymphoblastoid cell lines from patients with bipolar disorder

scientific article published on 19 September 2017

Early life stress decreases hippocampal BDNF content and exacerbates recognition memory deficits induced by repeated D-amphetamine exposure

scientific article published on 27 May 2011

Early life stress exacerbates cognitive dysfunction induced by d-amphetamine: amelioration by valproic acid

scientific article

Effects of beta-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: further evidence of antidepressant properties

scientific article published on 20 September 2009

Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice

scientific article published on 27 June 2012

Effects of moderate exercise on cigarette smoke exposure-induced hippocampal oxidative stress values and neurological behaviors in mice

scientific article published on 18 March 2010

Effects of mood stabilizers on hippocampus and amygdala BDNF levels in an animal model of mania induced by ouabain

scientific article published in December 2009

Elevated Plasma S100B, Psychotic Symptoms, and Cognition in Schizophrenia

scientific article published on 24 April 2017

Essential genes from genome-wide screenings as a resource for neuropsychiatric disorders gene discovery

scientific article published on 25 May 2021

Ethanol during adolescence decreased the BDNF levels in the hippocampus in adult male Wistar rats, but did not alter aggressive and anxiety-like behaviors

scientific article

Exosomal MicroRNAs as Potential Biomarkers in Neuropsychiatric Disorders

scientific article published in January 2018

Expression of dopamine signaling genes in the post-mortem brain of individuals with mental illnesses is moderated by body mass index and mediated by insulin signaling genes

article

Expression of matrix metalloproteinases in patients with bipolar disorder

scientific article published in October 2013

Genetics and epigenetics as tools to inform the pathophysiology of neuropsychiatric disorders

scientific article published on 01 January 2019

Genome-Wide Correlation of DNA Methylation and Gene Expression in Postmortem Brain Tissues of Opioid Use Disorder Patients

scientific article published on 01 November 2021

Genome-wide expression in veterans with schizophrenia further validates the immune hypothesis for schizophrenia

scientific article published on 19 June 2017

High Exploratory Phenotype Rats Exposed to Environmental Stressors Present Memory Deficits Accompanied by Immune-Inflammatory/Oxidative Alterations: Relevance to the Relationship Between Temperament and Mood Disorders

scientific article published on 05 August 2019

Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania

scientific article published on 10 December 2013

Hypothalamic-pituitary-adrenal axis dysfunction and illness progression in bipolar disorder.

scientific article

IL-6, TNF-α, IL-10, and nutritional status in pediatric patients with biliary atresia.

scientific article published on 19 March 2017

Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression

scientific article

Improvement of schizophrenia with electroconvulsive therapy and serum brain-derived neurotrophic factor levels: Lack of association in a pilot study

scientific article published on 01 December 2010

Increased neurotrophin-3 in drug-free subjects with bipolar disorder during manic and depressive episodes

scientific article published on 08 January 2010

Increased serum levels of eotaxin/CCL11 in late-stage patients with bipolar disorder: An accelerated aging biomarker?

scientific article published on 14 April 2015

Increased serum neurotrophin-4/5 levels in bipolar disorder

scientific article

Integrated transcriptome and methylome analysis in youth at high risk for bipolar disorder: a preliminary analysis

scientific article published on 14 March 2017

Lack of association between serum brain-derived neurotrophic factor levels and improvement of schizophrenia symptoms in a double-blind, randomized, placebo-controlled trial of memantine as adjunctive therapy to clozapine

scientific article published in January 2010

Memantine treatment reverses anhedonia, normalizes corticosterone levels and increases BDNF levels in the prefrontal cortex induced by chronic mild stress in rats

scientific article published on 11 February 2012

Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania

scientific article

Modeling mania in preclinical settings: A comprehensive review.

scientific article

Molecular Psychiatry: Trends and Study Examples

scientific article published on 10 January 2020

Moving pharmacoepigenetics tools for depression toward clinical use

scientific article published on 06 February 2019

N-acetylcysteine as a mitochondrial enhancer: a new class of psychoactive drugs?

scientific article published in December 2011

Neuroanatomical Profile of Antimaniac Effects of Histone Deacetylases Inhibitors

scientific article published on 22 March 2011

Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings

scientific article published on 03 April 2020

Neurochemical and behavioural effects of acute and chronic memantine administration in rats: Further support for NMDA as a new pharmacological target for the treatment of depression?

scientific article published on 30 November 2009

Neurotrophins, inflammation and oxidative stress as illness activity biomarkers in bipolar disorder

scientific article published on July 2013

Newer insights into the role of miRNA a tiny genetic tool in psychiatric disorders: focus on post-traumatic stress disorder.

scientific article

Non-genetic transgenerational transmission of bipolar disorder: targeting DNA methyltransferases

scientific article published on 4 October 2016

Peripheral biomarkers and illness activity in bipolar disorder

scientific article

Peripheral blood microRNA levels in females with cocaine use disorder

scientific article published on 02 April 2019

Peripheral insulin-like growth factor 1 in bipolar disorder

scientific article published on 23 January 2017

Peripheral toxicity in crack cocaine use disorders

scientific article published on 15 April 2013

Perturbations in the apoptotic pathway and mitochondrial network dynamics in peripheral blood mononuclear cells from bipolar disorder patients.

scientific article published on 2 May 2017

Plasma soluble L-selectin in medicated patients with schizophrenia and healthy controls

scientific article

Polygenic risk scores and their potential clinical use in psychiatry: are we there yet?

scientific article published on 16 March 2020

Prefrontal Cortex Corticotropin-Releasing Factor Receptor 1 Conveys Acute Stress-Induced Executive Dysfunction

scientific article published on 8 April 2016

Preliminary investigation of peripheral extracellular vesicles' microRNAs in bipolar disorder

scientific article published on 14 May 2019

Revisiting inflammation in bipolar disorder

scientific article published on 24 December 2018

Role of P2X7 Receptor in an Animal Model of Mania Induced by D-Amphetamine.

scientific article published on 11 December 2014

Serum levels of IL-6, IL-10 and TNF-α in patients with bipolar disorder and schizophrenia: differences in pro- and anti-inflammatory balance

scientific article published on 01 September 2011

Shortened telomere length in bipolar disorder: a comparison of the early and late stages of disease

scientific article published on 17 October 2016

Similarities in serum oxidative stress markers and inflammatory cytokines in patients with overt schizophrenia at early and late stages of chronicity

scientific article published on 20 April 2012

Staging and neuroprogression in bipolar disorder

scientific article published on December 2012

TSPO upregulation in bipolar disorder and concomitant downregulation of mitophagic proteins and NLRP3 inflammasome activation

scientific article published on 11 December 2018

Telomere Length, Oxidative Stress, Inflammation and BDNF Levels in Siblings of Patients with Bipolar Disorder: Implications for Accelerated Cellular Aging

scientific article

The FKBP5 polymorphism rs1360780 is associated with lower weight loss after bariatric surgery: 26 months of follow-up.

scientific article

The FKBP51 Glucocorticoid Receptor Co-Chaperone: Regulation, Function, and Implications in Health and Disease

scientific article published on 5 December 2017

The FKBP51-Glucocorticoid Receptor Balance in Stress-Related Mental Disorders.

scientific article published on 19 May 2015

The Role of BDNF as a Mediator of Neuroplasticity in Bipolar Disorder ⬇️

scientific article published on December 15, 2010

The effect of body mass index on glucagon-like peptide receptor gene expression in the post mortem brain from individuals with mood and psychotic disorders

article

The impact of body mass index in gene expression of reelin pathway mediators in individuals with schizophrenia and mood disorders: A post-mortem study

scientific article

The miRNome of bipolar disorder

scientific article

The role of DNA methylation in the pathophysiology and treatment of bipolar disorder.

scientific article published on 18 June 2016

Therapeutic use of omega-3 fatty acids in bipolar disorder.

scientific article published on July 2011

Total and mitochondrial nitrosative stress, decreased brain-derived neurotrophic factor (BDNF) levels and glutamate uptake, and evidence of endoplasmic reticulum stress in the hippocampus of vitamin A-treated rats

scientific journal article

Val66Met polymorphism and serum brain-derived neurotrophic factor in bipolar disorder: an open-label trial.

scientific article published on 20 August 2013

Vulnerability to dietary n-3 polyunsaturated fatty acid deficiency after exposure to early stress in rats

scientific article published on 26 March 2013

White matter deficits in cocaine use disorder: convergent evidence from in vivo diffusion tensor imaging and ex vivo proteomic analysis

scientific article published on 29 April 2021

List of works by Gabriel R. Fries

A promising era for epigenetic research: revealing the molecular signature of neuropsychiatric disorders

Accelerated aging in bipolar disorder: A comprehensive review of molecular findings and their clinical implications

Accelerated epigenetic aging and mitochondrial DNA copy number in bipolar disorder

Accelerated hippocampal biological aging in bipolar disorder

Acute administration of ketamine induces antidepressant-like effects in the forced swimming test and increases BDNF levels in the rat hippocampus

Administration of cannabidiol and imipramine induces antidepressant-like effects in the forced swimming test and increases brain-derived neurotrophic factor levels in the rat amygdala

Alterations in Plasma Kynurenine Pathway Metabolites in Children and Adolescents with Bipolar Disorder and Unaffected Offspring of Bipolar Parents: A preliminary study

Analyzing leukocyte telomere length in bipolar disorder: Authors' reply

Angiogenic gene networks are dysregulated in opioid use disorder: evidence from multi-omics and imaging of postmortem human brain

Anhedonia in cocaine use disorder is associated with inflammatory gene expression

Are lithium effects dependent on genetic/epigenetic architecture?

Biomarkers for bipolar disorder: current status and challenges ahead

Biomarkers in first-degree relatives of patients with bipolar disorder: what can they tell us?

Brain Gene Expression Pattern of Subjects with Completed Suicide and Comorbid Substance Use Disorder

Brain-derived neurotrophic factor and inflammatory markers in school-aged children with early trauma

Brain-derived neurotrophic factor as a state-marker of mood episodes in bipolar disorders: a systematic review and meta-regression analysis

Brain-derived neurotrophic factor gene val66met polymorphism and executive functioning in patients with bipolar disorder

Chaperoning epigenetics: FKBP51 decreases the activity of DNMT1 and mediates epigenetic effects of the antidepressant paroxetine

Childhood trauma, family history, and their association with mood disorders in early adulthood

Chronic administration of ketamine elicits antidepressant-like effects in rats without affecting hippocampal brain-derived neurotrophic factor protein levels

Cognition and functioning in bipolar depression

Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients

Damage-associated molecular patterns and immune activation in bipolar disorder

Decreased brain-derived neurotrophic factor in medicated and drug-free bipolar patients

Decreased serum neurotrophin 3 in chronically medicated schizophrenic males

Depression and Mania Induce Pro-inflammatory Activation of Macrophages Following Application of Serum from Individuals with Bipolar Disorder

Distinct lithium-induced gene expression effects in lymphoblastoid cell lines from patients with bipolar disorder

Early life stress decreases hippocampal BDNF content and exacerbates recognition memory deficits induced by repeated D-amphetamine exposure

Early life stress exacerbates cognitive dysfunction induced by d-amphetamine: amelioration by valproic acid

Effects of beta-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: further evidence of antidepressant properties

Effects of experimental cerebral malaria in memory, brain-derived neurotrophic factor and acetylcholinesterase activity [correction for acitivity] in the hippocampus of survivor mice

Effects of moderate exercise on cigarette smoke exposure-induced hippocampal oxidative stress values and neurological behaviors in mice

Effects of mood stabilizers on hippocampus and amygdala BDNF levels in an animal model of mania induced by ouabain

Elevated Plasma S100B, Psychotic Symptoms, and Cognition in Schizophrenia

Essential genes from genome-wide screenings as a resource for neuropsychiatric disorders gene discovery

Ethanol during adolescence decreased the BDNF levels in the hippocampus in adult male Wistar rats, but did not alter aggressive and anxiety-like behaviors

Exosomal MicroRNAs as Potential Biomarkers in Neuropsychiatric Disorders

Expression of dopamine signaling genes in the post-mortem brain of individuals with mental illnesses is moderated by body mass index and mediated by insulin signaling genes

Expression of matrix metalloproteinases in patients with bipolar disorder

Genetics and epigenetics as tools to inform the pathophysiology of neuropsychiatric disorders

Genome-Wide Correlation of DNA Methylation and Gene Expression in Postmortem Brain Tissues of Opioid Use Disorder Patients

Genome-wide expression in veterans with schizophrenia further validates the immune hypothesis for schizophrenia

High Exploratory Phenotype Rats Exposed to Environmental Stressors Present Memory Deficits Accompanied by Immune-Inflammatory/Oxidative Alterations: Relevance to the Relationship Between Temperament and Mood Disorders

Histone deacetylase activity and brain-derived neurotrophic factor (BDNF) levels in a pharmacological model of mania

Hypothalamic-pituitary-adrenal axis dysfunction and illness progression in bipolar disorder.

IL-6, TNF-α, IL-10, and nutritional status in pediatric patients with biliary atresia.

Impaired endoplasmic reticulum stress response in bipolar disorder: cellular evidence of illness progression

Improvement of schizophrenia with electroconvulsive therapy and serum brain-derived neurotrophic factor levels: Lack of association in a pilot study

Increased neurotrophin-3 in drug-free subjects with bipolar disorder during manic and depressive episodes

Increased serum levels of eotaxin/CCL11 in late-stage patients with bipolar disorder: An accelerated aging biomarker?

Increased serum neurotrophin-4/5 levels in bipolar disorder

Integrated transcriptome and methylome analysis in youth at high risk for bipolar disorder: a preliminary analysis

Lack of association between serum brain-derived neurotrophic factor levels and improvement of schizophrenia symptoms in a double-blind, randomized, placebo-controlled trial of memantine as adjunctive therapy to clozapine

Memantine treatment reverses anhedonia, normalizes corticosterone levels and increases BDNF levels in the prefrontal cortex induced by chronic mild stress in rats

Memory and brain-derived neurotrophic factor after subchronic or chronic amphetamine treatment in an animal model of mania

Modeling mania in preclinical settings: A comprehensive review.

Molecular Psychiatry: Trends and Study Examples

Moving pharmacoepigenetics tools for depression toward clinical use

N-acetylcysteine as a mitochondrial enhancer: a new class of psychoactive drugs?

Neuroanatomical Profile of Antimaniac Effects of Histone Deacetylases Inhibitors

Neurobiology of bipolar disorders: a review of genetic components, signaling pathways, biochemical changes, and neuroimaging findings

Neurochemical and behavioural effects of acute and chronic memantine administration in rats: Further support for NMDA as a new pharmacological target for the treatment of depression?

Neurotrophins, inflammation and oxidative stress as illness activity biomarkers in bipolar disorder

Newer insights into the role of miRNA a tiny genetic tool in psychiatric disorders: focus on post-traumatic stress disorder.

Non-genetic transgenerational transmission of bipolar disorder: targeting DNA methyltransferases

Peripheral biomarkers and illness activity in bipolar disorder

Peripheral blood microRNA levels in females with cocaine use disorder

Peripheral insulin-like growth factor 1 in bipolar disorder

Peripheral toxicity in crack cocaine use disorders

Perturbations in the apoptotic pathway and mitochondrial network dynamics in peripheral blood mononuclear cells from bipolar disorder patients.

Plasma soluble L-selectin in medicated patients with schizophrenia and healthy controls

Polygenic risk scores and their potential clinical use in psychiatry: are we there yet?

Prefrontal Cortex Corticotropin-Releasing Factor Receptor 1 Conveys Acute Stress-Induced Executive Dysfunction

Preliminary investigation of peripheral extracellular vesicles' microRNAs in bipolar disorder

Revisiting inflammation in bipolar disorder

Role of P2X7 Receptor in an Animal Model of Mania Induced by D-Amphetamine.

Serum levels of IL-6, IL-10 and TNF-α in patients with bipolar disorder and schizophrenia: differences in pro- and anti-inflammatory balance

Shortened telomere length in bipolar disorder: a comparison of the early and late stages of disease

Similarities in serum oxidative stress markers and inflammatory cytokines in patients with overt schizophrenia at early and late stages of chronicity