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List of works by Robert Hettich

(15)N- and (2)H proteomic stable isotope probing links nitrogen flow to archaeal heterotrophic activity.

scientific article published on 20 May 2014

53rd American Society for Mass Spectrometry Conference. 5-9 June, 2005, Henry B Gonzalez Conference Center, San Antonio, TX, USA

scientific article published on 01 August 2005

A comparative multidimensional LC-MS proteomic analysis reveals mechanisms for furan aldehyde detoxification in Thermoanaerobacter pseudethanolicus 39E

scientific article

A computational method for assessing peptide- identification reliability in tandem mass spectrometry analysis with SEQUEST.

scientific article published in April 2004

A graph-theoretic approach for the separation of b and y ions in tandem mass spectra

scientific article published on 28 September 2004

A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry.

scientific article

A nitrogenase-like enzyme system catalyzes methionine, ethylene, and methane biogenesis

scientific article published on 01 August 2020

A roadmap for research on crassulacean acid metabolism (CAM) to enhance sustainable food and bioenergy production in a hotter, drier world

scientific article

An active atmospheric methane sink in high Arctic mineral cryosols

scientific article published on 14 April 2015

Analysis of biostimulated microbial communities from two field experiments reveals temporal and spatial differences in proteome profiles

scientific article

Analysis of protein solvent accessible surfaces by photochemical oxidation and mass spectrometry

scientific article published in February 2004

Applications of mass spectrometry to DNA sequencing ⬇️

scientific article published on December 1, 1991

Attachment of two electrons to C60F48: Coulomb barriers in doubly charged anions

scientific article published on 01 November 1994

Biostimulation induces syntrophic interactions that impact C, S and N cycling in a sediment microbial community

scientific article published on 29 November 2012

Caldicellulosiruptor core and pangenomes reveal determinants for noncellulosomal thermophilic deconstruction of plant biomass

scientific article

Carbon-negative production of acetone and isopropanol by gas fermentation at industrial pilot scale

scientific article published in 2022

Characterization of Fatty Acids in Crenarchaeota by GC-MS and NMR.

scientific article published on 31 December 2015

Characterization of anaerobic catabolism of p-coumarate in Rhodopseudomonas palustris by integrating transcriptomics and quantitative proteomics

scientific article published on 20 December 2007

Characterization of cytochrome 579, an unusual cytochrome isolated from an iron-oxidizing microbial community

scientific article published on 9 May 2008

Characterization of monomeric and dimeric forms of recombinant Sml1p-histag protein by electrospray mass spectrometry

scientific article published on 01 February 2002

Characterization of pII family (GlnK1, GlnK2, and GlnB) protein uridylylation in response to nitrogen availability for Rhodopseudomonas palustris

scientific article published on 21 June 2006

Characterization of the 70S Ribosome from Rhodopseudomonas palustris using an integrated "top-down" and "bottom-up" mass spectrometric approach

scientific article published in September 2004

Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla

scholarly article

Characterizing the range of extracellular protein post-translational modifications in a cellulose-degrading bacteria using a multiple proteolyic digestion/peptide fragmentation approach

scientific article

Clostridium thermocellum ATCC27405 transcriptomic, metabolomic and proteomic profiles after ethanol stress

scientific article

Community genomic and proteomic analyses of chemoautotrophic iron-oxidizing "Leptospirillum rubarum" (Group II) and "Leptospirillum ferrodiazotrophum" (Group III) bacteria in acid mine drainage biofilms

scientific article

Community proteogenomics highlights microbial strain-variant protein expression within activated sludge performing enhanced biological phosphorus removal

scientific article

Community proteomics of a natural microbial biofilm

scientific article published on 5 May 2005

Comparative c-type cytochrome expression analysis in Shewanella oneidensis strain MR-1 and Anaeromyxobacter dehalogenans strain 2CP-C grown with soluble and insoluble oxidized metal electron acceptors

scientific article published on 01 December 2012

Comparative informatics analysis to evaluate site-specific protein oxidation in multidimensional LC-MS/MS data

scientific article

Comparative shotgun proteomic analysis of Clostridium acetobutylicum from butanol fermentation using glucose and xylose

scientific article (publication date: 18 October 2011)

Comparative temporal proteomics of a response regulator (SO2426)-deficient strain and wild-type Shewanella oneidensis MR-1 during chromate transformation

scientific article published in January 2009

Comparison of sustained off-resonance irradiation collisionally activated dissociation and multipole storage-assisted dissociation for top-down protein analysis

scientific article

Computational prediction and experimental validation of signal peptide cleavages in the extracellular proteome of a natural microbial community

scientific article

Contribution to the isolation and characterization of buckminsterfullerenes

scientific article published on 01 September 1992

Coupling a detergent lysis/cleanup methodology with intact protein fractionation for enhanced proteome characterization.

scientific article published on 19 November 2012

Critical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows

scientific article published on 15 December 2021

Critical biogeochemical functions in the subsurface are associated with bacteria from new phyla and little studied lineages

scientific article

Cultivation and quantitative proteomic analyses of acidophilic microbial communities

scientific article

Cytochrome 572 is a conspicuous membrane protein with iron oxidation activity purified directly from a natural acidophilic microbial community

scientific article published on 28 February 2008

DBDigger: reorganized proteomic database identification that improves flexibility and speed

scientific article published in April 2005

Defining the boundaries and characterizing the landscape of functional genome expression in vascular tissues of Populus using shotgun proteomics.

scientific article published on 9 November 2011

Deletion of the Cel48S cellulase from Clostridium thermocellum.

scientific article

Detecting differential and correlated protein expression in label-free shotgun proteomics

scientific article

Determination and comparison of the baseline proteomes of the versatile microbe Rhodopseudomonas palustris under its major metabolic states

scientific article published in February 2006

Determination of peptide and protein ion charge states by Fourier transformation of isotope-resolved mass spectra

scientific article published on 19 May 2006

Development of a multipoint quantitation method to simultaneously measure enzymatic and structural components of the Clostridium thermocellum cellulosome protein complex.

scientific article

Development of an electrochemical oxidation method for probing higher order protein structure with mass spectrometry.

scientific article

Development of an enhanced metaproteomic approach for deepening the microbiome characterization of the human infant gut.

scientific article

Differential accumulation of form I RubisCO in Rhodopseudomonas palustris CGA010 under Photoheterotrophic growth conditions with reduced carbon sources.

scientific article published on 17 April 2009

Direct cellular lysis/protein extraction protocol for soil metaproteomics

scientific article published on 15 November 2010

Discovery and annotation of small proteins using genomics, proteomics, and computational approaches

scientific article

Discrete and structurally unique proteins (tāpirins) mediate attachment of extremely thermophilic Caldicellulosiruptor species to cellulose.

scientific article

Diverse and divergent protein post-translational modifications in two growth stages of a natural microbial community

scientific article

Dosage-dependent proteome response of Shewanella oneidensis MR-1 to acute chromate challenge

scientific article published on 27 March 2007

Doubly charged negative ions of carbon-60

scientific article published on 01 September 1991

Dramatic performance of Clostridium thermocellum explained by its wide range of cellulase modalities.

scientific article published on 5 February 2016

Ecological distribution and population physiology defined by proteomics in a natural microbial community.

scientific article

Effects of diet on resource utilization by a model human gut microbiota containing Bacteroides cellulosilyticus WH2, a symbiont with an extensive glycobiome

scientific article

Effects of microbiota-directed foods in gnotobiotic animals and undernourished children

scientific article published on 01 July 2019

Elevated temperature alters proteomic responses of individual organisms within a biofilm community.

scientific article

Enhancing metaproteomics--The value of models and defined environmental microbial systems

scientific article published in December 2015

Enigmatic, ultrasmall, uncultivated Archaea.

scientific article

Environmental proteomics reveals early microbial community responses to biostimulation at a uranium- and nitrate-contaminated site.

scientific article

Environmental proteomics: a paradigm shift in characterizing microbial activities at the molecular level.

scientific article published on March 2009

Evaluation of an untargeted nano-liquid chromatography-mass spectrometry approach to expand coverage of low molecular weight dissolved organic matter in Arctic soil

scientific article published on 09 April 2019

Experimental approach for deep proteome measurements from small-scale microbial biomass samples.

scientific article

Experimental approach to controllably vary protein oxidation while minimizing electrode adsorption for boron-doped diamond electrochemical surface mapping applications

scientific article published on 17 December 2012

Exploiting the Dynamic Relationship between Peptide Separation Quality and Peptide Coisolation in a Multiple-Peptide Matches-per-Spectrum Approach Offers a Strategy To Optimize Bottom-Up Proteomics Throughput and Depth

scientific article published on 22 May 2019

Fermentation, hydrogen, and sulfur metabolism in multiple uncultivated bacterial phyla

scientific article published in September 2012

Formation and characterization of iron-oligonucleotide complexes with matrix-assisted laser desorption/ionization fourier transform ion cyclotron resonance mass spectrometry.

scientific article

Fullerenes from the geological environment.

scientific article

Fungi Contribute Critical but Spatially Varying Roles in Nitrogen and Carbon Cycling in Acid Mine Drainage

scientific article published on 3 March 2016

Genome-resolved metaproteomic characterization of preterm infant gut microbiota development reveals species-specific metabolic shifts and variabilities during early life.

scientific article published on 10 July 2017

Genomics-informed isolation and characterization of a symbiotic Nanoarchaeota system from a terrestrial geothermal environment

scientific article published on 05 July 2016

Geochemical, metagenomic and metaproteomic insights into trace metal utilization by methane-oxidizing microbial consortia in sulphidic marine sediments.

scientific article

Global molecular and morphological effects of 24-hour chromium(VI) exposure on Shewanella oneidensis MR-1.

scientific article

Heterotrophic archaea contribute to carbon cycling in low-pH, suboxic biofilm communities

scientific article

Identification and characterization of proteins of unknown function (PUFs) in Clostridium thermocellum DSM 1313 strains as potential genetic engineering targets

scientific article published on 10 May 2021

Identification and environmental distribution of dcpA, which encodes the reductive dehalogenase catalyzing the dichloroelimination of 1,2-dichloropropane to propene in organohalide-respiring chloroflexi

scientific article

Identification of biofilm matrix-associated proteins from an acid mine drainage microbial community.

scientific article

Identification of peptide-binding sites within BSA using rapid, laser-induced covalent cross-linking combined with high-performance mass spectrometry

scientific article published on 10 October 2017

Identification of phosphorylation sites on the yeast ribonucleotide reductase inhibitor Sml1.

scientific article

Impact of Fixed Nitrogen Availability on Dehalococcoides mccartyi Reductive Dechlorination Activity

scientific article published on 25 November 2019

Implications of strain- and species-level sequence divergence for community and isolate shotgun proteomic analysis.

scientific article published on 28 June 2007

Insights into plant biomass conversion from the genome of the anaerobic thermophilic bacterium Caldicellulosiruptor bescii DSM 6725

scientific article

Insights into the structure and metabolic function of microbes that shape pelagic iron-rich aggregates ("iron snow").

scientific article

Intact protein analysis for site-directed mutagenesis overexpression products: plasmid-encoded R67 dihydrofolate reductase

scientific article

Integrated metagenomics/metaproteomics reveals human host-microbiota signatures of Crohn's disease

scientific article

Integrating 'top-down" and "bottom-up" mass spectrometric approaches for proteomic analysis of Shewanella oneidensis

scientific article

Integrating experimental and computational approaches for the proteogenomic characterizations of microbial communities

scientific article

Investigation of UV matrix-assisted laser desorption fourier transform mass spectrometry for peptides

scientific article

Isolation and chemical analysis of nanoparticles from English ivy (Hedera helix L.).

scientific article published on 24 July 2013

Life on the edge: functional genomic response of Ignicoccus hospitalis to the presence of Nanoarchaeum equitans

scientific article

MASPIC: intensity-based tandem mass spectrometry scoring scheme that improves peptide identification at high confidence

scientific article published in December 2005

Mass spectrometric approaches for characterizing bacterial proteomes.

scientific article

Matrix-assisted laser desorption/ionization Fourier-transform mass spectrometry of oligodeoxyribonucleotides.

scientific article published on September 1993

Metabolome-proteome differentiation coupled to microbial divergence

scientific article

Metal affinity enrichment increases the range and depth of proteome identification for extracellular microbial proteins

scientific article published on 25 January 2012

Metaproteomics reveals functional shifts in microbial and human proteins during a preterm infant gut colonization case

scientific article published on 16 June 2015

Metaproteomics reveals persistent and phylum-redundant metabolic functional stability in adult human gut microbiomes of Crohn's remission patients despite temporal variations in microbial taxa, genomes, and proteomes

scientific article published on 11 February 2019

Metaproteomics: harnessing the power of high performance mass spectrometry to identify the suite of proteins that control metabolic activities in microbial communities

scientific article published on 21 March 2013

Methyl guanine isomer distinction by hydrogen / deuterium exchange using a fourier transform mass spectrometer

scientific article published on 01 April 1993

Microbes in thawing permafrost: the unknown variable in the climate change equation

scientific article

Microbial metaproteomics for characterizing the range of metabolic functions and activities of human gut microbiota

scientific article

Microbial metaproteomics: identifying the repertoire of proteins that microorganisms use to compete and cooperate in complex environmental communities.

scientific article

Microbial proteomics: the quiet revolution ⬇️

scientific article published on May 23, 2012

Molecular dynamics of the Shewanella oneidensis response to chromate stress

scientific article published on 8 March 2006

Moving away from the reference genome: evaluating a peptide sequencing tagging approach for single amino acid polymorphism identifications in the genus Populus

scientific article published on 23 July 2013

Multipole-storage-assisted dissociation for the characterization of large proteins and simple protein mixtures by ESI-FTICR-MS

scientific article published on 01 May 2005

New group in the Leptospirillum clade: cultivation-independent community genomics, proteomics, and transcriptomics of the new species "Leptospirillum group IV UBA BS".

scientific article

Nitrogen cycling. The environmental controls that govern the end product of bacterial nitrate respiration.

scientific article published in August 2014

Optimized Extraction Method To Remove Humic Acid Interferences from Soil Samples Prior to Microbial Proteome Measurements

scientific article

PTMSearchPlus: software tool for automated protein identification and post-translational modification characterization by integrating accurate intact protein mass and bottom-up mass spectrometric data searches

scientific article published in October 2009

Phage-induced expression of CRISPR-associated proteins is revealed by shotgun proteomics in Streptococcus thermophilus

scientific article (publication date: 2012)

Phenotype fingerprinting suggests the involvement of single-genotype consortia in degradation of aromatic compounds by Rhodopseudomonas palustris

scientific article (publication date: 2009)

Photochemical surface mapping of C14S-Sml1p for constrained computational modeling of protein structure.

scientific article

Phytoplankton exudates and lysates support distinct microbial consortia with specialized metabolic and ecophysiological traits

scientific article published in 2021

Posttranslational modification and sequence variation of redox-active proteins correlate with biofilm life cycle in natural microbial communities.

scientific article published on 20 May 2010

ProRata: A quantitative proteomics program for accurate protein abundance ratio estimation with confidence interval evaluation.

scientific article published in October 2006

Profile of secreted hydrolases, associated proteins, and SlpA in Thermoanaerobacterium saccharolyticum during the degradation of hemicellulose.

scientific article

Progress and Challenges in Ocean Metaproteomics and Proposed Best Practices for Data Sharing

article

Protein surface mapping by chemical oxidation: structural analysis by mass spectrometry

scientific article published in February 2003

Proteogenomic approaches for the molecular characterization of natural microbial communities

scientific article

Proteogenomic basis for ecological divergence of closely related bacteria in natural acidophilic microbial communities.

scientific article

Proteogenomic monitoring of Geobacter physiology during stimulated uranium bioremediation

scientific article published on 28 August 2009

Proteome changes in the initial bacterial colonist during ecological succession in an acid mine drainage biofilm community

scientific article published on 25 April 2011

Proteomic Stable Isotope Probing Reveals Biosynthesis Dynamics of Slow Growing Methane Based Microbial Communities

scientific article published on 29 April 2016

Proteomic characterization of cellular and molecular processes that enable the Nanoarchaeum equitans--Ignicoccus hospitalis relationship.

scientific article

Proteomics reveals a core molecular response of Pseudomonas putida F1 to acute chromate challenge

scientific article

Proteomics-inferred genome typing (PIGT) demonstrates inter-population recombination as a strategy for environmental adaptation.

scientific article published on 23 September 2008

Putting the pieces together: high-performance LC-MS/MS provides network-, pathway-, and protein-level perspectives in Populus.

scientific article published on 16 October 2012

Quantitative proteomic analyses of the response of acidophilic microbial communities to different pH conditions

scientific article

Quantitative tracking of isotope flows in proteomes of microbial communities

scientific article

Recoding of the stop codon UGA to glycine by a BD1-5/SN-2 bacterium and niche partitioning between Alpha- and Gammaproteobacteria in a tidal sediment microbial community naturally selected in a laboratory chemostat

scientific article

Rescuing Those Left Behind: Recovering and Characterizing Underdigested Membrane and Hydrophobic Proteins To Enhance Proteome Measurement Depth

scientific article

Robust estimation of peptide abundance ratios and rigorous scoring of their variability and bias in quantitative shotgun proteomics.

scientific article published in October 2006

Role of the CipA scaffoldin protein in cellulose solubilization, as determined by targeted gene deletion and complementation in Clostridium thermocellum

scientific article published on 30 November 2012

Shotgun metaproteomics of the human distal gut microbiota

article

Shotgun proteomic monitoring of Clostridium acetobutylicum during stationary phase of butanol fermentation using xylose and comparison with the exponential phase

scientific article published on 07 March 2012

Simultaneous achievement of high ethanol yield and titer in Clostridium thermocellum.

scientific article published on 02 June 2016

Sml1p is a dimer in solution: characterization of denaturation and renaturation of recombinant Sml1p

scientific article

Strain-resolved community proteomics reveals recombining genomes of acidophilic bacteria.

scientific article published on 7 March 2007

Strain-resolved microbial community proteomics reveals simultaneous aerobic and anaerobic function during gastrointestinal tract colonization of a preterm infant ⬇️

scientific article published on July 2015

Strategies for metagenomic-guided whole-community proteomics of complex microbial environments

scientific article

Structural Characterization of Normal and Modified Oligonucleotides by Matrix-assisted Laser Desorption Fourier Transform Mass Spectrometry

scientific article

Structural characterization of polycyclic aromatic hydrocarbon dihydrodiol epoxide DNA adducts using matrix-assisted laser desorption/ionization Fourier transform mass spectrometry

scientific article published on 01 April 1994

Synthesis and Characterization of Molybdenum Carbide Clusters MonC4n, (n = 1 to 4).

scientific article

Systematic assessment of the benefits and caveats in mining microbial post-translational modifications from shotgun proteomic data: the response of Shewanella oneidensis to chromate exposure

scientific article

Systematic comparison of label-free, metabolic labeling, and isobaric chemical labeling for quantitative proteomics on LTQ Orbitrap Velos

scientific article published on 16 February 2012

Systems biology: Functional analysis of natural microbial consortia using community proteomics

scientific article published on March 2009

Targeted Growth Medium Dropouts Promote Aromatic Compound Synthesis in Crude E. coli Cell-Free Systems

scientific article published on 12 October 2020

The differentiation of methyl guanosine isomers by laser ionization Fourier transform mass spectrometry.

scientific article

The diversity and specificity of the extracellular proteome in the cellulolytic bacterium Caldicellulosiruptor bescii is driven by the nature of the cellulosic growth substrate

scientific article published on 23 March 2018

The effects of micronutrient deficiencies on bacterial species from the human gut microbiota.

scientific article

The temporal analysis of yeast exponential phase using shotgun proteomics as a fermentation monitoring technique

scientific article published on 15 June 2012

Transcriptomic and proteomic characterization of the Fur modulon in the metal-reducing bacterium Shewanella oneidensis

scientific article

Untargeted metabolomics studies employing NMR and LC-MS reveal metabolic coupling between Nanoarcheum equitans and its archaeal host Ignicoccus hospitalis.

scientific article published in August 2015

Use of label-free quantitative proteomics to distinguish the secreted cellulolytic systems of Caldicellulosiruptor bescii and Caldicellulosiruptor obsidiansis

scientific article

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